Panama City cruise port guide
You probably can’t think of Panama City without conjuring images of the Panama Canal. But nearly 400 years before the Panama Canal opened its locks, Panama City was making its mark. From the vestiges of the original settlement to the modern skyscrapers, experience the history and culture of one of the Pacific Coast’s oldest continuously inhabited European settlements. After exploring the bustling local markets in search of fresh fish or artisan handicrafts, admire the restored Spanish Colonial architecture in Casco Viejo. Or you can head to the Miraflores Locks and watch one of the modern world’s most heroic feats of engineering in action.
About Panama City
Panama City is the capital and largest city of Panama, situated at the Pacific Ocean entrance to the Panama Canal. Cruise ships dock at either Port Fuerte Amador (a tender port on a man-made causeway connecting four small islands) or Port Balboa. The city offers a striking juxtaposition of modern skyscrapers and UNESCO-listed historic Casco Viejo district.
The Miraflores Locks visitor center offers grandstand views of container ships and cruise liners rising and falling through the locks. Casco Viejo, the 17th-century walled city quarter, is a UNESCO World Heritage Site with beautifully restored colonial buildings, boutique hotels, and atmospheric restaurants. The Biomuseo, designed by Frank Gehry, tells the story of Panama as the land bridge that reconnected the Americas.
Quick facts
Cruises visiting Panama City
Prices per person · incl. taxes & fees.
Sailing soonest
Panama Canal - Ocean to Ocean
Island Princess · North America · 16 nights
from $2,092
$130 / night
Panama Canal & Pacific Coast
Coral Princess · Caribbean · 22 nights
from $2,652
$120 / night
Panama Canal & Pacific Coast
Star Princess · Pacific Northwest · 23 nights
from $2,639
$114 / night
Panama Canal - Ocean to Ocean
Coral Princess · Central America · 16 nights
from $2,133
$133 / night
Panama Canal - Ocean to Ocean
Star Princess · Caribbean · 16 nights
from $1,645
$102 / night
Ultimate America's Historic Journey to Panama
Scenic Eclipse · North America · 21 nights
from $52,280
$2,489 / night
Showing the 20 least-expensive of 108 sailings.
Showing 108 Panama City cruises
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Dec 3, 2026 | 16 |
from $1,206 $75 / night |
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Apr 4, 2027 | 16 |
from $1,366 $85 / night |
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Dec 13, 2027 | 16 |
from $1,432 $89 / night |
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Jan 30, 2028 | 16 |
from $1,435 $89 / night |
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Feb 15, 2028 | 16 |
from $1,435 $89 / night |
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Apr 3, 2027 | 16 |
from $1,447 $90 / night |
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Dec 12, 2026 | 16 |
from $1,518 $94 / night |
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Apr 22, 2028 | 16 |
from $1,534 $95 / night |
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Apr 3, 2027 | 16 |
from $1,560 $97 / night |
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Apr 19, 2027 | 16 |
from $1,567 $97 / night |
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Nov 6, 2026 | 16 |
from $1,576 $98 / night |
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Jan 14, 2028 | 16 |
from $1,610 $100 / night |
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Oct 24, 2027 | 16 |
from $1,634 $102 / night |
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Dec 29, 2027 | 16 |
from $1,635 $102 / night |
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Oct 4, 2026 | 16 |
from $1,645 $102 / night |
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Oct 13, 2026 | 16 |
from $1,679 $104 / night |
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Jan 6, 2027 | 15 |
from $1,704 $113 / night |
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Mar 2, 2028 | 16 |
from $1,715 $107 / night |
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Apr 3, 2028 | 16 |
from $1,715 $107 / night |
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Mar 18, 2028 | 16 |
from $1,720 $107 / night |
