Panama Canal - Ocean to Ocean

The Panama Canal - Ocean to Ocean is a 16-night Central America cruise aboard Star Princess, operated by Princess Cruises. Departing Los Angeles, CA on October 10, 2027, the voyage visits 6 ports. Fares start from $1,998 per person.

Length: 16 nights
Departs: Oct 10, 2027
Returns: Oct 26, 2027
Ports of call: 6
Days at sea: 11

from $1,998

$124 / night per person, incl. taxes & fees

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Itinerary

Day 1 Oct 10, 2027 Los Angeles, CA Departs 15:00 Los Angeles is a huge city with a thousand facets and attractions, one of the most stimulating urban centers that can be visited ever. Your MSC World Cruise will take you on the discovery of a place that has no equal, with its golden Pacific beaches, theme parks from the film world and walks down Sunset Boulevard with the Walk of Fame and its various museums. Los Angeles is perfect for those who enjoy shopping, entertainment and relaxation for a truly unforgettable vacation. What will the main stops on your MSC Cruises excursion be? No doubt a visit to Beverly Hills, the exclusive center of fashion and beauty where you can admire a multitude of homes in full California style. This residential area is famous for its proximity to Hollywood and for being home to many movie stars, as well as for hosting some of the most beautiful restaurants, shops and hotels in the world. And how could you not visit impressive Malibu, the seaside town in the west of the coast of Los Angeles. The beaches here are the best for swimming and sunbathing, thanks to the beautiful landscape that accompanies them, the jagged mountains of the Santa Monica Mountains National Recreation Area. Not far from Malibu is Santa Monica, another glittering attraction known for its famous Luna Park that was built on the pier in 1909. This bustling city is also popular for its climate, the beauty of the coast, the efficiency of its services, its clubs, shops and lively pedestrian streets that are full of street artists who have made Santa Monica one of the main destinations of Los Angeles. With MSC Cruises, you will have the chance to see one of the most beautiful cities in the world with your own eyes. Los Angeles, CA port guide Search cruises visiting Los Angeles, CA

Los Angeles, CA photo — Day 1 Oct 10, 2027 Los Angeles, CA Departs 15:00 Los Angeles is a huge city with a thousand facets and attractions, one of the most stimulating urban centers that can be visited ever. Your MSC World Cruise will take you on the discovery of a place that has no equal, with its golden Pacific beaches, theme parks from the film world and walks down Sunset Boulevard with the Walk of Fame and its various museums. Los Angeles is perfect for those who enjoy shopping, entertainment and relaxation for a truly unforgettable vacation. What will the main stops on your MSC Cruises excursion be? No doubt a visit to Beverly Hills, the exclusive center of fashion and beauty where you can admire a multitude of homes in full California style. This residential area is famous for its proximity to Hollywood and for being home to many movie stars, as well as for hosting some of the most beautiful restaurants, shops and hotels in the world. And how could you not visit impressive Malibu, the seaside town in the west of the coast of Los Angeles. The beaches here are the best for swimming and sunbathing, thanks to the beautiful landscape that accompanies them, the jagged mountains of the Santa Monica Mountains National Recreation Area. Not far from Malibu is Santa Monica, another glittering attraction known for its famous Luna Park that was built on the pier in 1909. This bustling city is also popular for its climate, the beauty of the coast, the efficiency of its services, its clubs, shops and lively pedestrian streets that are full of street artists who have made Santa Monica one of the main destinations of Los Angeles. With MSC Cruises, you will have the chance to see one of the most beautiful cities in the world with your own eyes. Los Angeles, CA port guide Search cruises visiting Los Angeles, CA

Day 4 Oct 13, 2027 Cabo San Lucas 07:00 – 18:00 11.0 hrs ashore Found at the tip of Baja California, Cabo San Lucas is where the desert meets the ocean. Although it has received a makeover of modern Americana in recent years, this place is still a world away from everywhere else in Mexico. A trip to Cabo (the San Lucas is optional) will not leave you disappointed. With swaying palm trees, turquoise seas and long ribbons of white sand, this is a resort that ticks every box: great food, great nightlight which equal great times – for some. Others may prefer to scratch the surface just a bit deeper and travel along the peninsula that is known for its dramatic scenery of desert terrain and rugged coastline marked by many unusual formations. The sweeping views of the bay are simply sensational. A quick turn inward takes you to San Jose del Cabo, Cabo San Lucas’ older and more grown up sister. Offering a very much calmer and much more authentic atmosphere, just half an hour along the coast leaves you in its desert terrain, and leaves a very different impression from the lively beachfront bars and cafes of San Lucas. Perhaps one of the most stunning ways to see Cabo though is from the water. With the Arco de Cabo San Lucas featuring highly on many must-see lists, a trip around the bay is a must. The braver among you might also like to indulge their inner adrenalin junkie and swim with whale sharks – a memorable and totally risk-free experience if there ever was one. End your day of sightseeing with a fabulous sunset, a (tequila) sunrise in hand, watching the fishermen come home from their adventures. Cabo San Lucas port guide Search cruises visiting Cabo San Lucas

Cabo San Lucas photo — Day 4 Oct 13, 2027 Cabo San Lucas 07:00 – 18:00 11.0 hrs ashore Found at the tip of Baja California, Cabo San Lucas is where the desert meets the ocean. Although it has received a makeover of modern Americana in recent years, this place is still a world away from everywhere else in Mexico. A trip to Cabo (the San Lucas is optional) will not leave you disappointed. With swaying palm trees, turquoise seas and long ribbons of white sand, this is a resort that ticks every box: great food, great nightlight which equal great times – for some. Others may prefer to scratch the surface just a bit deeper and travel along the peninsula that is known for its dramatic scenery of desert terrain and rugged coastline marked by many unusual formations. The sweeping views of the bay are simply sensational. A quick turn inward takes you to San Jose del Cabo, Cabo San Lucas’ older and more grown up sister. Offering a very much calmer and much more authentic atmosphere, just half an hour along the coast leaves you in its desert terrain, and leaves a very different impression from the lively beachfront bars and cafes of San Lucas. Perhaps one of the most stunning ways to see Cabo though is from the water. With the Arco de Cabo San Lucas featuring highly on many must-see lists, a trip around the bay is a must. The braver among you might also like to indulge their inner adrenalin junkie and swim with whale sharks – a memorable and totally risk-free experience if there ever was one. End your day of sightseeing with a fabulous sunset, a (tequila) sunrise in hand, watching the fishermen come home from their adventures. Cabo San Lucas port guide Search cruises visiting Cabo San Lucas

Day 5 Oct 14, 2027 Mazatlan, Mexico 08:00 – 18:00 10.0 hrs ashore Book a Mexico Cruise with Holland America Line and sail to the port city of Mazatlán, where the best of traditional Mexican architecture, food and culture is found alongside contemporary conveniences, amenities and attractions. There's a reason why Americans and Canadians flock here, particularly in winter: It's a warm and welcoming place with plenty to keep visitors entertained for a vacation getaway. Cruise to Mazatlán and explore an array of activities on a Mazatlán shore excursion. There really is something for everyone here, from golfing, fishing and zip lining to sampling agave-based spirits on a distillery tour or learning more about local history at the archaeological museum. There are plenty of cultural opportunities, too, from performances at the Teatro Ángela Peralta to witnessing death-defying cliff dives that will make you hold your breath until divers resurface from the churning surf. On a cruise to Mazatlán don’t forgot to taste some local cuisine. Mazatlán keeps visitors' appetites sated; thanks to the city's coastal location, seafood is freshly caught, and shrimp-based dishes are a particular specialty in local restaurants. And if you can't head home without a souvenir, there's locally made liquor or handmade crafts that can fit neatly into your luggage.

Day 11 Oct 20, 2027 Panama City 07:00 – 21:00 14.0 hrs ashore You probably can’t think of Panama City without conjuring images of the Panama Canal. But nearly 400 years before the Panama Canal opened its locks, Panama City was making its mark. From the vestiges of the original settlement to the modern skyscrapers, experience the history and culture of one of the Pacific Coast’s oldest continuously inhabited European settlements. After exploring the bustling local markets in search of fresh fish or artisan handicrafts, admire the restored Spanish Colonial architecture in Casco Viejo. Or you can head to the Miraflores Locks and watch one of the modern world’s most heroic feats of engineering in action. Panama City port guide Search cruises visiting Panama City

Panama City photo — Day 11 Oct 20, 2027 Panama City 07:00 – 21:00 14.0 hrs ashore You probably can’t think of Panama City without conjuring images of the Panama Canal. But nearly 400 years before the Panama Canal opened its locks, Panama City was making its mark. From the vestiges of the original settlement to the modern skyscrapers, experience the history and culture of one of the Pacific Coast’s oldest continuously inhabited European settlements. After exploring the bustling local markets in search of fresh fish or artisan handicrafts, admire the restored Spanish Colonial architecture in Casco Viejo. Or you can head to the Miraflores Locks and watch one of the modern world’s most heroic feats of engineering in action. Panama City port guide Search cruises visiting Panama City

Day 14 Oct 23, 2027 Oranjestad, Aruba 07:00 – 16:00 9.0 hrs ashore Located in the southern Caribbean, Aruba stands out with its desert-like vistas, wind-shaped trees, natural rock formations and breath-taking beaches. Its terrain offers plenty of opportunity for exploration and off-road trekking. As you arrive on an MSC Caribbean and Antilles cruise in Oranjestad, the tax-free capital named after William I (the Prince of Orange and the first King of the Netherlands), admire the city’s charming Dutch Colonial architecture with its antique buildings and houses that blend in with today’s modern architecture. Not much grows on Aruba. However, its hot dry climate is ideal for aloe farming. Book an MSC excursion to the Aruba Aloe Museum & Factory, and learn about the 160-year history of aloe farming on the island. If adventure is on your agenda, get on a UTV on an MSC excursion that will take you through Aruba's outback, skirting along the coastline with visits to the Alto Vista Chapel, the Bushiribana Gold Mill ruins that remind us of Aruba's 19th-century gold rush, and to the early 20th-century California Lighthouse, which bears the name of an unfortunate ship that sank nearby in 1891. An on-road driving MSC excursion will visit those sites as well, along with the amazing Casibari Rock Formation, or huge diorite boulders found in the centre of the island. Take a “Natural Aruba” MSC excursion to tour the Butterfly Farm, then pass countless divi divi trees and cacti before arriving at Aruba’s Natural Bridge, a wonder carved out of solid coral by the relentlessly pounding surf. Or relax in the calm waters lapping Arashi Beach and Palm Beach, while snorkelers will enjoy our catamaran sailing excursion that explores Boca Cathalina and the “Antilla” World War II shipwreck, considered to be one of the top dive and snorkel sites of the Caribbean. Oranjestad, Aruba port guide Search cruises visiting Oranjestad, Aruba

Day 17 Oct 26, 2027 Port Canaveral, Florida Arrives 07:00 The beach is just the beginning of the adventures that await guests visiting Port Canaveral, located on the Atlantic coast of Central Florida. The white sands along the beach are made for long days in the sun, while the waters are ideal for sports, including some of the best surfing on the East Coast. Waterfront restaurants serve local seafood and festive drinks on patios overlooking the cruise ships’ arrivals and departures. Nearby, Cocoa Village offers tree-lined streets to stroll while shopping. Port Canaveral, on Florida’s Space Coast, is an ideal launching spot to get to the nearby Kennedy Space Center and to Orlando’s famous theme parks, which are between 60 and 90 minutes away by car. Guests get to see NASA treasures and experience a space-shuttle-launch simulator and even have the chance to meet a veteran astronaut among the adventures at the Kennedy Space Center. Walt Disney World, SeaWorld Orlando and Universal Orlando Resort offer thrill rides, shows and attractions, and invite guests into their themed worlds of fun. Port Canaveral, Florida port guide Search cruises visiting Port Canaveral, Florida

Port Canaveral, Florida photo — Day 17 Oct 26, 2027 Port Canaveral, Florida Arrives 07:00 The beach is just the beginning of the adventures that await guests visiting Port Canaveral, located on the Atlantic coast of Central Florida. The white sands along the beach are made for long days in the sun, while the waters are ideal for sports, including some of the best surfing on the East Coast. Waterfront restaurants serve local seafood and festive drinks on patios overlooking the cruise ships’ arrivals and departures. Nearby, Cocoa Village offers tree-lined streets to stroll while shopping. Port Canaveral, on Florida’s Space Coast, is an ideal launching spot to get to the nearby Kennedy Space Center and to Orlando’s famous theme parks, which are between 60 and 90 minutes away by car. Guests get to see NASA treasures and experience a space-shuttle-launch simulator and even have the chance to meet a veteran astronaut among the adventures at the Kennedy Space Center. Walt Disney World, SeaWorld Orlando and Universal Orlando Resort offer thrill rides, shows and attractions, and invite guests into their themed worlds of fun. Port Canaveral, Florida port guide Search cruises visiting Port Canaveral, Florida

Pricing

Lowest fare we've tracked over the observed 92-day span: $1,398 · range $1,398–$1,998

Current prices

Per person · 2 guests · incl. taxes & fees

Inside

from $1,998

$124 / night

Fare rows

Interior

Cabin grade

Available

from $1,998

$124 / night

per person · incl. taxes

Oceanview

from $2,298

$143 / night

Fare rows

Premium Oceanview

Cabin grade

Available

from $2,298

$143 / night

per person · incl. taxes

Balcony

from $2,598

$162 / night

Fare rows

Cove Balcony

Cabin grade

Available

from $2,598

$162 / night

per person · incl. taxes

Suite

from $3,848

$240 / night

Fare rows

Mini-Suite

Cabin grade

Available

from $3,848

$240 / night

per person · incl. taxes

Prices verified Jun 23, 2026

Prices come from third-party data feeds via Princess Cruises and may differ from the cruise line's current fare. Confirm the final price before booking. How our pricing works

Show all 35 cabin grades

Name	Supplier code	Type
Not listed
Sanctuary Balcony	D0	Balcony
Premium Deluxe Balcony	D1	Balcony
Premium Deluxe Balcony	D2	Balcony
Deluxe Balcony	DA	Balcony
Deluxe Balcony	DB	Balcony
Deluxe Balcony	DC	Balcony
Deluxe Balcony	DD	Balcony
Deluxe Balcony	DE	Balcony
Deluxe Balcony	DF	Balcony
Cove Balcony	DG	Balcony
Cove Balcony	DH	Balcony
Interior	IA	Inside
Interior	IB	Inside
Interior	IC	Inside
Interior	ID	Inside
Interior	IE	Inside
Interior	IF	Inside
Interior	IS	Inside
Premium Oceanview	O2	Oceanview
Premium Oceanview	O3	Oceanview
Premium Oceanview	O5	Oceanview
Cabana Mini-Suite	C1	Suite
Cabana Mini-Suite	C2	Suite
Cabana Mini-Suite	CA	Suite
Cabana Mini-Suite	CB	Suite
Sanctuary Mini-Suite	M1	Suite
Sanctuary Mini-Suite	M2	Suite
Mini-Suite	MA	Suite
Mini-Suite	MD	Suite
Mini-Suite	ME	Suite
Sky Suite	S0	Suite
Owner's Suite	S2	Suite
Penthouse Suite	S4	Suite
Signature Suite	S9	Suite