Skip to main content

All 52 sailings from Panama City

Ordered soonest first. Prices per person, including taxes and fees. Want to filter by price, date, or ship?

Open these cruises in search →
All 52 sailings from Panama City
View SailingDeparts NightsShip From
Wellness Retreat - Panama City to Valparaiso Oct 26, 20269 Scenic Eclipse

Call for price

Panama and Colombia: Exploring the Caribbean Coast - Eastbound Oct 31, 20267 National Geographic Quest

from $3,500

$500 / night

Panama and Colombia: Exploring the Caribbean Coast - Eastbound Nov 7, 20267 National Geographic Quest

from $10,600

$1,514 / night

The Panama Canal, Pearl Islands and Darién Jungle - Southbound Dec 6, 20267 National Geographic Quest

from $12,500

$1,785 / night

The Panama Canal, Pearl Islands and Darién Jungle - Northbound Dec 13, 20267 National Geographic Quest

from $6,000

$857 / night

Costa Rica and the Panama Canal - Westbound Dec 20, 20267 National Geographic Quest

from $7,630

$1,090 / night

Costa Rica and the Panama Canal - Westbound Jan 3, 20277 National Geographic Quest

from $9,000

$1,285 / night

Panama City To Miami Jan 15, 202710 Marina

Call for price

Panama City to Papeete (Tahiti) Jan 26, 202728 Seven Seas Splendor

from $22,399

$799 / night

The Panama Canal, Pearl Islands and Darién Jungle - Southbound Jan 29, 20277 National Geographic Quest

from $16,000

$2,285 / night

Costa Rica and the Panama Canal - Westbound Feb 6, 20277 National Geographic Quest

from $18,500

$2,642 / night

Costa Rica and the Panama Canal - Westbound Feb 20, 20277 National Geographic Quest

from $18,500

$2,642 / night

Panama City to Miami, FL Feb 22, 202711 Seven Seas Prestige

from $11,899

$1,081 / night

Costa Rica and the Panama Canal - Westbound Mar 6, 20277 National Geographic Quest

from $18,500

$2,642 / night

Journey to the Amazon - Panama City to Panama City Mar 9, 202722 Seven Seas Grandeur

from $25,449

$1,156 / night

Panama City To Miami Mar 15, 202710 Marina

from $3,899

$389 / night

Costa Rica and the Panama Canal - Westbound Mar 20, 20277 National Geographic Quest

from $16,000

$2,285 / night

Panama City to Miami, FL Mar 31, 202714 Seven Seas Grandeur

from $9,749

$696 / night

Pristine islands of the Caribbean & the Panama Canal Apr 3, 202711 Scenic Eclipse II

from $10,089

$917 / night

Panama and Costa Rica: Crossing the Canal Oct 4, 20279 Douglas Mawson

from $9,196

$1,021 / night

Ancient Kingdoms and Natural Treasures: Panama to Chile Oct 31, 202713 Scenic Eclipse

from $13,869

$1,066 / night

Ultimate Ancient Treasures, Fjords & Wonders of South America Oct 31, 202725 Scenic Eclipse

from $34,867

$1,394 / night

The Panama Canal, Pearl Islands and Darién Jungle - Northbound Nov 5, 20277 National Geographic Quest

Call for price

Panama and Colombia: Exploring the Caribbean Coast - Eastbound Nov 12, 20277 National Geographic Quest

Call for price

Panama and Colombia: Exploring the Caribbean Coast - Eastbound Nov 19, 20277 National Geographic Quest

Call for price

Costa Rica and the Panama Canal - Westbound Dec 4, 20277 National Geographic Quest

from $15,000

$2,142 / night

Panama City to Miami Dec 12, 202711 Nautica

Call for price

Costa Rica and the Panama Canal - Westbound Dec 23, 20277 National Geographic Quest

from $14,500

$2,071 / night

Costa Rica and the Panama Canal - Westbound Jan 6, 20287 National Geographic Quest

from $13,600

$1,942 / night

Pura vida – Costa Rica up close - Panama City to Panama City Jan 7, 202813 MS EUROPA 2

from $10,914

$839 / night

Grenadines, Colombia & Panama Canal transit Jan 13, 202811 Emerald Azzurra

from $10,296

$936 / night

Panama City To Miami Jan 16, 202810 Marina

from $3,099

$309 / night

The great diversity of the Caribbean Sea - Panama City to Miami Jan 20, 202819 MS EUROPA 2

from $14,651

$771 / night

Coastal Adventures Panama City to San Jose Jan 24, 20287 Emerald Azzurra

from $5,460

$780 / night

The Panama Canal, Pearl Islands and Darién Jungle - Northbound Jan 29, 20287 National Geographic Quest

from $12,300

$1,757 / night

Panama City to Miami Feb 4, 202810 Nautica

Call for price

Costa Rica and the Panama Canal - Westbound Feb 5, 20287 National Geographic Quest

from $15,000

$2,142 / night

Costa Rica and the Panama Canal - Westbound Feb 19, 20287 National Geographic Quest

from $15,000

$2,142 / night

Panama Canal transit, Colombia & Grenadines Feb 29, 202811 Emerald Azzurra

from $10,296

$936 / night

The Panama Canal, Pearl Islands and Darién Jungle - Southbound Mar 9, 20287 National Geographic Quest

from $13,500

$1,928 / night

Panama City to Miami, FL Mar 14, 202812 Seven Seas Prestige

from $7,699

$641 / night

Panama City to Lisbon Mar 14, 202826 Seven Seas Prestige

from $17,499

$673 / night

Panama City To Miami Mar 15, 202810 Marina

from $3,149

$314 / night

The Panama Canal, Pearl Islands and Darién Jungle - Northbound Mar 16, 20287 National Geographic Quest

from $13,500

$1,928 / night

Costa Rica and the Panama Canal - Westbound Mar 23, 20287 National Geographic Quest

from $14,500

$2,071 / night

Ultimate Voyage: South America & Antarctica Oct 24, 202836 Scenic Eclipse

Call for price

Ancient Kingdoms & Natural Treasures: Panama to Chile Oct 24, 202814 Scenic Eclipse

Call for price

Grenadines, Colombia & Panama Canal transit Jan 13, 202911 Emerald Azzurra

from $10,647

$967 / night

Panama City (Pacific Cruise Terminal) to Miami, FL Jan 19, 202912 Vista

from $4,999

$416 / night

Coastal Adventures Panama City to San Jose Jan 24, 20297 Emerald Azzurra

from $7,677

$1,096 / night

Panama City, Panama to Miami, Florida Feb 11, 202911 Sonata

from $5,699

$518 / night

Panama Canal transit, Colombia & Grenadines Mar 1, 202911 Emerald Azzurra

from $10,647

$967 / night

The Captain's Log

Exceptional cruises. Intelligent prices.

Weekly newsletter. Cruises worth a look, with the price history to know when to book.