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Journey to the Amazon - Panama City to Panama City

The Journey to the Amazon - Panama City to Panama City is a 22-night Central America cruise aboard Seven Seas Grandeur, operated by Regent Seven Seas Cruises. Departing Panama City on March 9, 2027, the voyage visits 10 ports. Fares start from $20,949 per person.

Length
22 nights
Departs
Mar 9, 2027
Returns
Mar 31, 2027
Ports of call
10
Days at sea
10

Itinerary

Panama City
Panama City photo
Panama City photo
Panama City photo
Day 1 Mar 9, 2027 Panama City Departs 17:00 You probably can’t think of Panama City without conjuring images of the Panama Canal. But nearly 400 years before the Panama Canal opened its locks, Panama City was making its mark. From the vestiges of the original settlement to the modern skyscrapers, experience the history and culture of one of the Pacific Coast’s oldest continuously inhabited European settlements. After exploring the bustling local markets in search of fresh fish or artisan handicrafts, admire the restored Spanish Colonial architecture in Casco Viejo. Or you can head to the Miraflores Locks and watch one of the modern world’s most heroic feats of engineering in action. Panama City port guide Search cruises visiting Panama City

Round-trip from Panama City · approximate route

Pricing

Lowest fare we've tracked over the observed 90-day span: $17,299 · range $17,299–$20,949

Current prices

Per person · 2 guests · incl. taxes & fees

Inside

Not available

Oceanview

Not available

Balcony

Not available

Suite

from $20,949

$952 / night

Fare rows

Deluxe Veranda Suite

Cabin grade

Available

from $20,949

$952 / night

per person · incl. taxes

Deluxe Veranda Suite

Cabin grade

Available

from $20,999

$954 / night

per person · incl. taxes

Concierge Suite

Cabin grade

Available

from $22,399

$1,018 / night

per person · incl. taxes

Serenity Suite

Cabin grade

Available

from $22,399

$1,018 / night

per person · incl. taxes

Concierge Suite

Cabin grade

Available

from $23,049

$1,047 / night

per person · incl. taxes

Deluxe Veranda Suite

Cabin grade

Available

from $24,049

$1,093 / night

per person · incl. taxes

Deluxe Veranda Suite

Cabin grade

Available

from $24,099

$1,095 / night

per person · incl. taxes

Serenity Suite

Cabin grade

Available

from $25,499

$1,159 / night

per person · incl. taxes

Concierge Suite

Cabin grade

Available

from $25,699

$1,168 / night

per person · incl. taxes

Concierge Suite

Cabin grade

Available

from $26,349

$1,197 / night

per person · incl. taxes

Penthouse Suite

Cabin grade

Available

from $31,299

$1,422 / night

per person · incl. taxes

Penthouse Suite

Cabin grade

Available

from $33,049

$1,502 / night

per person · incl. taxes

Penthouse Suite

Cabin grade

Available

from $34,599

$1,572 / night

per person · incl. taxes

Penthouse Suite

Cabin grade

Available

from $36,349

$1,652 / night

per person · incl. taxes

Signature Suite

Cabin grade

Available

from $64,449

$2,929 / night

per person · incl. taxes

Signature Suite

Cabin grade

Available

from $67,749

$3,079 / night

per person · incl. taxes

Prices verified Jun 22, 2026

Prices come from third-party data feeds via Regent Seven Seas Cruises and may differ from the cruise line's current fare. Confirm the final price before booking. How our pricing works

Price history

30 days
Show all 15 cabin grades
Name Supplier code Type
Penthouse Suite A Suite
Penthouse Suite B Suite
Penthouse Suite C Suite
Concierge Suite D Suite
Concierge Suite E Suite
Serenity Suite F1 Suite
Serenity Suite F2 Suite
Deluxe Veranda Suite G1 Suite
Deluxe Veranda Suite G2 Suite
Grandeur Suite GN Suite
Grand Suite GS Suite
Veranda Suite H Suite
Regent Suite RS Suite
Signature Suite SG Suite
Seven Seas Suite SS Suite

Ship

Seven Seas Grandeur
Your ship Seven Seas Grandeur 6★ 55,498 GT 746 guests Built 2021 For more than thirty years, we have delivered unrivaled experiences throughout the world. All the while, we have been listening to our guests, evolving our services and continually refining each element of the Regent experience. Embrace the freedom enjoyed through the most all-inclusive luxury experience on the Seven Seas aboard a ship that elevates the pinnacle of ocean cruising to new heights. Inspired by the past and stunningly reimagined for the future, Seven Seas Grandeur™ will exemplify our heritage of perfection with unrivaled space, unparalleled service, exceptional cuisine and transformative experiences that will begin the moment you step aboard. Seven Seas Grandeur ship guide Search cruises on Seven Seas Grandeur
Deck plan for Deck 4

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Fly-cruise options

Airport Price pp Included
ABQ $62,389.00 Extra
ALB $62,379.00 Extra
ATL $62,409.00 Extra
AUS $62,399.00 Extra
AVL $62,299.00 Extra
BDL $62,379.00 Extra
BFL $62,309.00 Extra
BHM $62,349.00 Extra
BIL $62,389.00 Extra
BNA $62,349.00 Extra
BOI $62,389.00 Extra
BOS $62,309.00 Extra
BUF $62,379.00 Extra
BWI $62,409.00 Extra
CHA $62,349.00 Extra
CHS $62,299.00 Extra
CID $62,399.00 Extra
CLE $62,349.00 Extra
CLT $62,349.00 Extra
CMH $62,349.00 Extra
COS $62,389.00 Extra
CVG $62,349.00 Extra
DCA $62,409.00 Extra
DEN $62,639.00 Extra
DFW $62,359.00 Extra
DSM $62,399.00 Extra
DTW $62,249.00 Extra
ELP $62,389.00 Extra
EUG $62,309.00 Extra
EWR $62,409.00 Extra
FAR $62,399.00 Extra
FAT $62,309.00 Extra
FLL $62,309.00 Extra
FSD $62,399.00 Extra
GEG $62,309.00 Extra
GRR $62,349.00 Extra
GSO $62,309.00 Extra
GSP $62,299.00 Extra
GTF $62,389.00 Extra
HNL $62,309.00 Extra
HSV $62,349.00 Extra
IAD $62,409.00 Extra
IAH $62,549.00 Extra
ICT $62,399.00 Extra
ILM $62,299.00 Extra
IND $62,349.00 Extra
JAN $62,409.00 Extra
JAX $62,319.00 Extra
JFK $62,409.00 Extra
LAS $62,389.00 Extra
LAX $62,429.00 Extra
LBB $62,399.00 Extra
LEX $62,349.00 Extra
LGA $62,409.00 Extra
LIT $62,399.00 Extra
MAF $62,399.00 Extra
MCI $62,399.00 Extra
MCO $62,369.00 Extra
MDW $62,359.00 Extra
MEM $62,349.00 Extra
MIA $62,309.00 Extra
MKE $62,399.00 Extra
MOB $62,349.00 Extra
MSN $62,399.00 Extra
MSP $62,319.00 Extra
MSY $62,399.00 Extra
MYR $62,299.00 Extra
OKC $62,399.00 Extra
OMA $62,399.00 Extra
ORD $62,359.00 Extra
ORF $62,299.00 Extra
PBI $62,309.00 Extra
PDX $62,309.00 Extra
PHL $62,409.00 Extra
PHX $62,329.00 Extra
PIA $62,399.00 Extra
PIT $62,349.00 Extra
PSP $62,309.00 Extra
PVD $62,379.00 Extra
PWM $62,379.00 Extra
RDU $62,299.00 Extra
RIC $62,299.00 Extra
RNO $62,389.00 Extra
ROC $62,379.00 Extra
RSW $62,319.00 Extra
SAN $62,409.00 Extra
SAT $62,439.00 Extra
SAV $62,259.00 Extra
SBA $62,309.00 Extra
SDF $62,349.00 Extra
SEA $62,529.00 Extra
SFO $62,449.00 Extra
SGF $62,399.00 Extra
SHV $62,399.00 Extra
SLC $62,389.00 Extra
SMF $62,309.00 Extra
SNA $62,429.00 Extra
STL $62,399.00 Extra
SYR $62,379.00 Extra
TPA $62,289.00 Extra
TUL $62,399.00 Extra
TUS $62,389.00 Extra
TYS $62,349.00 Extra
XNA $62,399.00 Extra
YEG $62,389.00 Extra
YOW $62,379.00 Extra
YUL $62,389.00 Extra
YVR $62,349.00 Extra
YYC $62,389.00 Extra
YYJ $62,309.00 Extra
YYZ $62,409.00 Extra