21-Day Panama Canal & Eastern Caribbean: U.s. Virgin Islands
The 21-Day Panama Canal & Eastern Caribbean: U.s. Virgin Islands is a 21-night South America cruise aboard Nieuw Amsterdam, operated by Holland America Line. Departing Fort Lauderdale on February 28, 2027, the voyage visits 12 ports. Fares start from $4,379 per person.
- Length
- 21 nights
- Departs
- Feb 28, 2027
- Returns
- Mar 21, 2027
- Ports of call
- 12
- Days at sea
- 9
from $4,379 pp
via CruiseDirect
Book direct with Holland America Line we may earn a commission
Itinerary
Round-trip from Fort Lauderdale · approximate route
Pricing
Lowest fare we've tracked over the observed 86-day span: $4,029 · range $4,029–$4,379
Current prices
Per person · 2 guests · incl. taxes & fees
Inside
from $4,379
$208 / night
Fare rows
Standard Interior Stateroom
Cabin grade
from $4,379
$208 / night
per person · incl. taxes
Standard Interior Stateroom
Cabin grade
from $4,479
$213 / night
per person · incl. taxes
Standard Interior Stateroom
Cabin grade
from $4,539
$216 / night
per person · incl. taxes
Standard Interior Stateroom
Cabin grade
from $4,599
$219 / night
per person · incl. taxes
Large/Standard Inside Stateroom
Cabin grade
from $4,659
$221 / night
per person · incl. taxes
Large/Standard Inside Stateroom
Cabin grade
from $4,719
$224 / night
per person · incl. taxes
Large Interior Stateroom
Cabin grade
from $4,779
$227 / night
per person · incl. taxes
Interior Spa Stateroom
Cabin grade
from $4,839
$230 / night
per person · incl. taxes
Oceanview
from $5,009
$238 / night
Fare rows
Large Ocean view Stateroom (Fully Obstructed View)
Cabin grade
from $5,009
$238 / night
per person · incl. taxes
Large Ocean view Stateroom (Fully Obstructed View)
Cabin grade
from $5,139
$244 / night
per person · incl. taxes
Large Ocean view Stateroom
Cabin grade
from $5,189
$247 / night
per person · incl. taxes
Large Ocean view Stateroom (Partial Sea View)
Cabin grade
from $5,239
$249 / night
per person · incl. taxes
Large Ocean view Stateroom
Cabin grade
from $5,289
$251 / night
per person · incl. taxes
Large Ocean view Stateroom
Cabin grade
from $5,389
$256 / night
per person · incl. taxes
Large Ocean view Stateroom
Cabin grade
from $5,489
$261 / night
per person · incl. taxes
Large Ocean view Stateroom
Cabin grade
from $5,589
$266 / night
per person · incl. taxes
Large Ocean view Spa Stateroom
Cabin grade
from $5,689
$270 / night
per person · incl. taxes
Balcony
from $5,769
$274 / night
Fare rows
Verandah Stateroom
Cabin grade
from $5,769
$274 / night
per person · incl. taxes
Verandah Stateroom
Cabin grade
from $5,949
$283 / night
per person · incl. taxes
Verandah Stateroom
Cabin grade
from $6,089
$289 / night
per person · incl. taxes
Verandah Stateroom
Cabin grade
from $6,229
$296 / night
per person · incl. taxes
Verandah Stateroom
Cabin grade
from $6,369
$303 / night
per person · incl. taxes
Verandah Stateroom
Cabin grade
from $6,509
$309 / night
per person · incl. taxes
Verandah Stateroom
Cabin grade
from $6,649
$316 / night
per person · incl. taxes
Verandah Stateroom
Cabin grade
from $6,789
$323 / night
per person · incl. taxes
Verandah Spa Stateroom
Cabin grade
from $6,929
$329 / night
per person · incl. taxes
Suite
from $9,009
$429 / night
Fare rows
Signature Suite
Cabin grade
from $9,009
$429 / night
per person · incl. taxes
Signature Suite
Cabin grade
from $9,409
$448 / night
per person · incl. taxes
Neptune Suite
Cabin grade
from $11,259
$536 / night
per person · incl. taxes
Neptune Suite
Cabin grade
from $12,069
$574 / night
per person · incl. taxes
Neptune Suite
Cabin grade
from $12,879
$613 / night
per person · incl. taxes
Prices verified Jun 22, 2026
Prices come from third-party data feeds via Holland America Line and may differ from the cruise line's current fare. Confirm the final price before booking. How our pricing works
Price history
30 days
○ = last available date (sold out, or no longer listed).
Show all 34 cabin grades
Ship
Similar cruises
Other sailing dates
Same itinerary, different dates. Prices per person · incl. taxes & fees.
Compare similar cruises
7 Night Southern Caribbean Cruise
Grandeur of the Seas · South America · 7 nights
from $1,136
$162 / night
per person · incl. taxes
7 Night Southern Caribbean Cruise
Grandeur of the Seas · South America · 7 nights
Call for price
per person · incl. taxes
Eastern/western Caribbean Adventurer
Regal Princess · North America · 14 nights
from $2,303
$164 / night
per person · incl. taxes
Eastern/western Caribbean Adventurer
Regal Princess · Central America · 14 nights
Call for price
per person · incl. taxes
Galápagos Islands - Nine of the Best Isles plus Machu Picchu
MS Santa Cruz II · South America · 15 nights
Call for price
per person · incl. taxes
Galápagos Islands - Nine of the Best Isles plus Machu Picchu
MS Santa Cruz II · South America · 15 nights
Call for price
per person · incl. taxes
from $4,379 pp
via CruiseDirect
Book direct with Holland America Line we may earn a commission