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Civitavecchia, Rome

25 nights · Western Mediterranean

25-night Western Mediterranean cruise: Civitavecchia, Rome to La Romana on MSC Opera

The 25 nights South Caribbean from Civitavecchia (Rome) is a 25-night Western Mediterranean cruise aboard MSC Opera, operated by MSC Cruises. Departing Civitavecchia, Rome on October 29, 2026 and arriving in La Romana on November 23, 2026, the voyage visits 15 ports including Genoa, Italy, Livorno, Marseille, France. Fares start from $5,145 per person.

Length
25 nights
Departs
Oct 29, 2026
Returns
Nov 23, 2026
Ports of call
15
Days at sea
10

Voyage code OX20261029CVVLR1

from $5,145 pp

via CruiseDirect

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Why this route stands out

A closer look at the journey

Fixed editorial images from the places on this itinerary. They stay stable each time you return to this sailing.

Civitavecchia, Rome

All roads lead to Rome, and with good reason - this city is one of the world’s most thrilling, offering unmatched history along every street. An evocative, inspiring and utterly artistic capital of unrivalled cultural impact, Rome is a city of back-to-back landmarks, which will take you on an exhilarating journey through the ages. This may be one of the world’s oldest cities, but it’s well and truly lived in. The ruins are punctuated with murmuring cafes, and the outdoor seating of restaurants sprawls out across piazzas, enticing you to sample tangles of creamy pasta and crispy pizzas. Rome’s incredible Roman Forum is littered with the ruins of its ancient administrations, which have stood firm for 2,000 years, since the times when the area was the centre of the Western world. Few sites are more simultaneously beautiful and haunting than that of the storied Colosseum, which looms deep into Rome’s rich blue sky. Take a tour to learn details of the grisly goings-on within. The best way to experience Rome is to wander its streets, gelato in hand. There is a lot to see here - whether it’s the domed spectacle of the Pantheon, or the elaborate flowing waters and artistry of the Trevi Fountain. Vatican City is an astonishing, colossal display of Catholic grandeur, while the Spanish Steps – crowned by the Trinità dei Monti church – offer a beautiful spot to gather and soak up the lively atmosphere of this humming city. With so much on the to-do list, you’ll relish the breaks you take, enjoying simple pleasures like a strong espresso, or fresh pasta with tomato sauce and ripped basil.

Genoa, Italy

Genoa is marvellously eclectic, vibrant and full of rough-edged style; it’s a great cruise excursion. Indeed “La Superba” (The Superb), as it was known at the height of its authority as a Mediterranean superpower, boasts more zest and intrigue than all the surrounding coastal resorts put together. During a holiday to Genoa you can explore its old town: a dense and fascinating warren of medieval alleyways home to large palazzi built in the sixteenth and seventeenth centuries by Genoa’s wealthy mercantile families and now transformed into museums and art galleries. You should seek out the Cattedrale di San Lorenzo, the Palazzo Ducale, and the Renaissance palaces of Via Garibaldi which contain the cream of Genoa’s art collections, as well as furniture and decor from the grandest days of the city’s past, when its ships sailed to all corners of the Mediterranean Sea. The Acquario di Genova is the city’s pride and joy, parked like a giant ocean liner on the waterfront, with seventy tanks housing sea creatures from all the world’s major habitats, including the world’s biggest reconstruction of a Caribbean coral reef. It’s a great aquarium by any standards, the second largest in Europe by capacity, and boasts a fashionably ecology-conscious slant and excellent background information in Italian and English. Just 35 km south of Genoa, there’s no denying the appeal of Portofino, tucked into a protected inlet surrounded by lush cypress- and olive-clad slopes. It’s an A-list resort that has been attracting high-flying bankers, celebs and their hangers-on for years, as evidenced by the flotillas of giant yachts usually anchored just outside. It’s a tiny place that is attractive yet somehow off-putting at the same time, with a quota of fancy shops, bars and restaurants for a place twice its size.

Livorno

There are few more elegant places to salute the sunset than Terrazza Mascagni, Livorno’s refined chessboard piazza. A historic port, and a beachy gateway to Tuscany, Livorno welcomes you ashore to explore this enchanted Italian region's sun-soaked beauty, rich flavours and world-renowned fine art. Stay in Livorno to explore 'Piccolo Venezia', or ‘Little Venice’ - a quarter of the town that's laced with canals, little marble bridges and plenty of tempting eateries. View less With its bustling market, fortresses and iconic waterfront, there’s plenty to keep you busy here, but most will be tempted to venture inland to explore more of Tuscany’s many charms and artistic wonders. Test your nose, as you breathe in the subtleties of Tuscany’s vineyard-draped scenery, and visit wineries showcasing the best of the renowned flavours of the Bolgheri wine-growing area. Or head out to Prato, where you’ll find tightly-woven textile history. Pisa’s showpiece tower is within reach, as is Florence’s city of immense and imaginative renaissance beauty. Admire the delicate carving of Michelangelo's masterpiece, the David statue, and note the provocative stance as he casts a dismissive glance towards Rome. Stand before the city’s majestic black and white cathedral - the Cathedral of Santa Maria del Fiore - with its colossal brick dome. The view down over Florence's river and grand dome from Piazzale Michelangelo, meanwhile, is one of Italy's finest. However you choose to spend your time in Tuscany, you’ll discover an artistic region, filled with beauty designed to appeal to every sense.

Price tracking

Today’s fare, in context

Price history

Cheaper than 85%
90 days
Fare details

Fare details

Per person · taxes & fees included
Current fares
Verified 7 hours ago
Balcony
$5,145
Tracked range
150 days
Price history by cabin type
CabinCurrentLowestHighest
Inside $2,000 $1,349 on Jun 20 $2,236 on Apr 19
Oceanview $2,742 $1,758 on Jun 20 $5,959 on Jul 16
Balcony $5,145 $3,781 on May 15 $10,541 on Jul 14
Suite $5,855 $5,775 on Jun 16 $11,973 on Jul 14
Cabin grades
12 total
BALCONY AUREABalcony · BA
BALCONY BELLA GUARANTEEDBalcony · BB
JUNIOR BALCONY FANTASTICABalcony · BM1
INTERIOR BELLA GUARANTEEDInside · IB
JUNIOR INTERIOR FANTASTICAInside · IM1
JUNIOR INTERIOR FANTASTICAInside · IM2
OCEAN VIEW BELLA GUARANTEEDOceanview · OB
PREMIUM OCEAN VIEW FANTASTICAOceanview · OL1
JUNIOR OCEAN VIEW FANTASTICAOceanview · OM1
JUNIOR OCEAN VIEW FANTASTICAOceanview · OM2
JUNIOR OCEAN VIEW WITH OBSTRUCTED VIEW FANTASTICAOceanview · OO
DELUXE SUITE AUREASuite · SR1

○ = last seen (sold out or delisted). · Verified 7 hours ago.

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Current prices

Per person · 2 guests · incl. taxes & fees

Inside

Not available

Oceanview

Not available

Balcony

from $5,145

$205 / night

Fare rows

BALCONY AUREA

Cabin grade

Available

from $5,145

$205 / night

per person · incl. taxes & fees

BALCONY AUREA

Cabin grade

Available

from $5,145

$205 / night

per person · incl. taxes & fees

BALCONY AUREA

Cabin grade

Available

from $6,495

$259 / night

per person · incl. taxes & fees

BALCONY AUREA

Cabin grade

Available

from $10,541

$421 / night

per person · incl. taxes & fees

Suite

Not available

Prices verified Aug 28, 2026

Prices come from third-party data feeds via MSC Cruises and may differ from the cruise line's current fare. Confirm the final price before booking. How our pricing works

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The journey

25 nights, in order

Follow the entire sailing from its first day to its last, with the route and schedule in one view.

Civitavecchia, Rome

Day 1 Oct 29, 2026

Civitavecchia, Rome

All roads lead to Rome, and with good reason - this city is one of the world’s most thrilling, offering unmatched history along every street.

Explore Civitavecchia, Rome

Day by day

The full itinerary

26 scheduled calls
MSC Opera

Your ship

MSC Opera

With its impressive array of new features and facilities, MSC Opera is now even better equipped to satisfy the needs of our guests. We’ve added spacious new cabins with balconies offering superb panoramic views and we have enlarged the restaurant and buffet areas to serve up an even greater variety of culinary treats. There is even a new 330 m² music and dance area for guests to show off their moves.

4★ 65,591 GT 2,579 Passengers Built 2004
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