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16-night South America cruise: Fort Lauderdale (Port Everglades) to San Antonio, Chile on Oosterdam

The 16-Day Inca & Panama Canal Discovery: Lima Overnight is a 16-night South America cruise aboard Oosterdam, operated by Holland America Line. Departing Fort Lauderdale on November 18, 2026 and arriving in San Antonio, Chile on December 4, 2026, the voyage visits 9 ports including George Town, Cayman Islands, Fuerte Amador, Panama City, Manta. Fares start from $1,804 per person.

Length
16 nights
Departs
Nov 18, 2026
Returns
Dec 4, 2026
Ports of call
9
Days at sea
7

Voyage code O670

Fort Lauderdale (Port Everglades)

16 nights · South America

from $1,804 pp

via CruiseDirect

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Why this route stands out

A closer look at the journey

Fort Lauderdale (Port Everglades)

With its heady mix of Creole culture and French sophistication, there is more than a pinch of je ne sais quoi in Fort de France. The capital of Martinique, and by far the biggest city in the whole of the French West Indies, if you are looking for Paris in the Caribbean, you’ll find it in Fort de France. The island has been under French govern since 1638 when the first governor of Martinique Jacques Dyel du Parquet commissioned a fort (from which the city takes its name) to keep out invaders. Not even an unsuccessful attack by the British in 1720, nor the French Revolution in 1789, has been able to shake the French govern of the island and today the city’s French and Creole heritage are impossible to untangle. The colonial past is everywhere, take a stroll down the narrow streets and enjoy the remarkable architecture of the Schœlcher Library, St. Louis Cathedral and the Old Town Hall. Among the many legacies Dyel du Parquet left on the island is sugarcane. A drive through the tropical forests will not only reward you with trees bending under the weight of papayas, mangoes and bananas, but will also afford superb vistas of the elegant plant swaying in the breeze. The arrival and subsequent export of sugar brought the French bourgeoisie in their droves and many of their mansions are still standing. Josephine de Beauharnais, the Napoleonic Empress of “not tonight” fame, hails from the island and those interested will find her childhood home, La Pagerie in nearby Trois Ilets.

George Town, Cayman Islands

Christopher Columbus called the Cayman Islands, with their tranquil blue waters, "Las Tortugas" for its abundance of turtles. Located between Cuba and Jamaica, the Cayman Islands are comprised of three Caribbean islands: Grand Cayman, Little Cayman and Cayman Brac. Beautiful landscapes, bountiful wildlife and colourful streets embody this British Overseas Territory, with George Town, its capital, located on Grand Cayman, the largest and most populous island. When you arrive in George Town on an MSC Caribbean and Antilles cruise, you’ll discover that wildlife conservation is at the core of Grand Cayman’s offerings. For the chance of a lifetime to swim, feed and interact with stingrays, book an MSC excursion to Stingray City, where you’ll get an up-close experience with Cayman’s most graceful marine creatures. On yet another MSC excursion to the Cayman Turtle Centre, encounter the green turtles that return each and every year to lay their eggs on one of the beaches, visit the turtle hatchery, snorkel alongside yearlings in the Turtle Lagoon and meet the island’s endangered blue iguanas. For a special experience, ride horses bareback into the Caribbean Sea at Barker’s National Park on an exclusive Martha Stewart excursion curated just for MSC Cruises, followed by lunch at Vivo café, a spot beloved for its mostly vegan cuisine, with organic ingredients sourced straight from local farms. To learn about Cayman’s past and culture, explore Cayman Heritage House and visit the sumptuous Government House, the governor's residence built in 1964 located in front of Seven Mile Beach, one of the most prestigious beaches of Grand Cayman, in the heart of West Bay. Shopaholics will also delight in this destination. The Cayman Islands are entirely duty free. You just have to choose what catches your fancy among the myriad of watches, liqueurs, jewellery and porcelain on offer.

Manta

The breezy, seaside city of Manta is the second largest port in Ecuador and possesses one of the world's most varied terrains. To the west of Manta lie the Galapagos Islands. To the east rises the great rampart of the Andes. The Mantas were known for their traditional balsa rafts in the coastal waters and their ceramics and pottery. A huge tuna statue greets you on its shores, a whimsical nod to the tuna capital of the world. Fresh seafood is always on the menu, and a stroll along the promenade lets you take in the beach scene. The bustling center of town, an easy walk from port, displays a lively marketplace selling Panama hats, silver jewelry and apparel. There is lush green parkland; the nearby colonial town of Montecristi, the center of the Panama hat industry; and the Pacoche Wildlife Refuge, home to indigenous flora and fauna and cheeky howler monkeys. Explore the rich culture, heritage and people of Manta during scenic adventures that take in the Archaeological Museum, which highlights a small, well-curated collection of ceramics of the Manteño-Huancavilca culture that flourished here between 800 and 1550 A.D. Whether you explore its past or its vibrant city of today, a day in Manta is a rich and colorful experience. Note: Manta offers little in the way of tourist infrastructure. Transportation and tour guides are imported to the area. Despite the sometimes hot and humid conditions there is no guarantee of air-conditioned vehicles.

Price tracking

Today’s fare, in context

Price history

90 days
Fare details

Fare details

Per person · taxes & fees included
Current fares
Verified 6 hours ago
Inside
$1,804
Oceanview
$3,044
Balcony
$3,894
Suite
$3,554
Tracked range
169 days
Price history by cabin type
CabinCurrentLowestHighest
Inside $1,804 $1,804 on Sep 3 $3,454 on Jul 5
Oceanview $3,044 $2,004 on Jul 29 $3,504 on Jul 5
Balcony $3,894 $2,554 on Jul 29 $4,454 on Jun 4
Suite $3,554 $3,554 on Sep 3 $5,694 on Mar 25
Cabin grades
29 total
Verandah StateroomBalcony · VA
Verandah StateroomBalcony · VB
Verandah StateroomBalcony · VC
Verandah StateroomBalcony · VD
Verandah StateroomBalcony · VE
Verandah StateroomBalcony · VF
Verandah StateroomBalcony · VH
Large/Standard Inside StateroomInside · I
Large Interior StateroomInside · J
Large/Standard Inside StateroomInside · K
Standard Interior StateroomInside · L
Standard Interior StateroomInside · M
Large/Standard Inside StateroomInside · MM
Standard Interior StateroomInside · N
Large Ocean view StateroomOceanview · C
Large Ocean view StateroomOceanview · D
Large Ocean view StateroomOceanview · DD
Large Ocean view StateroomOceanview · E
Large Ocean view StateroomOceanview · F
Large Ocean view Stateroom (Partial Sea View)Oceanview · G
Large Ocean view Stateroom (Fully Obstructed View)Oceanview · H
Large Ocean view Stateroom (Fully Obstructed View)Oceanview · HH
Pinnacle SuiteSuite · PS
Neptune SuiteSuite · SA
Neptune SuiteSuite · SB
Neptune SuiteSuite · SC
Signature SuiteSuite · SS
Signature SuiteSuite · SY
Signature SuiteSuite · SZ

○ = last seen (sold out or delisted). · Verified 6 hours ago.

Lowest fares with no residency, age, or service requirement — verify eligibility at booking. How our pricing works

Current prices

Per person · 2 guests · incl. taxes & fees

Inside

from $1,804

$112 / night

Fare rows

Standard Interior Stateroom

Cabin grade

Available

from $1,804

$112 / night

per person · incl. taxes & fees

Standard Interior Stateroom

Cabin grade

Available

from $2,034

$127 / night

per person · incl. taxes & fees

Large/Standard Inside Stateroom

Cabin grade

Available

from $3,054

$190 / night

per person · incl. taxes & fees

Standard Interior Stateroom

Cabin grade

Available

from $3,074

$192 / night

per person · incl. taxes & fees

Standard Interior Stateroom

Cabin grade

Available

from $3,094

$193 / night

per person · incl. taxes & fees

Large/Standard Inside Stateroom

Cabin grade

Available

from $3,114

$194 / night

per person · incl. taxes & fees

Large Interior Stateroom

Cabin grade

Available

from $3,134

$195 / night

per person · incl. taxes & fees

Large/Standard Inside Stateroom

Cabin grade

Available

from $3,154

$197 / night

per person · incl. taxes & fees

Oceanview

from $3,044

$190 / night

Fare rows

Large Ocean view Stateroom (Fully Obstructed View)

Cabin grade

Available

from $3,044

$190 / night

per person · incl. taxes & fees

Large Ocean view Stateroom

Cabin grade

Available

from $3,094

$193 / night

per person · incl. taxes & fees

Large Ocean view Stateroom (Fully Obstructed View)

Cabin grade

Available

from $3,134

$195 / night

per person · incl. taxes & fees

Large Ocean view Stateroom

Cabin grade

Available

from $3,144

$196 / night

per person · incl. taxes & fees

Large Ocean view Stateroom (Partial Sea View)

Cabin grade

Available

from $3,184

$199 / night

per person · incl. taxes & fees

Large Ocean view Stateroom

Cabin grade

Available

from $3,194

$199 / night

per person · incl. taxes & fees

Large Ocean view Stateroom

Cabin grade

Available

from $3,244

$202 / night

per person · incl. taxes & fees

Large Ocean view Stateroom

Cabin grade

Available

from $3,294

$205 / night

per person · incl. taxes & fees

Balcony

from $3,894

$243 / night

Fare rows

Verandah Stateroom

Cabin grade

Available

from $3,894

$243 / night

per person · incl. taxes & fees

Verandah Stateroom

Cabin grade

Available

from $4,014

$250 / night

per person · incl. taxes & fees

Verandah Stateroom

Cabin grade

Available

from $4,104

$256 / night

per person · incl. taxes & fees

Verandah Stateroom

Cabin grade

Available

from $4,194

$262 / night

per person · incl. taxes & fees

Verandah Stateroom

Cabin grade

Available

from $4,284

$267 / night

per person · incl. taxes & fees

Verandah Stateroom

Cabin grade

Available

from $4,374

$273 / night

per person · incl. taxes & fees

Verandah Stateroom

Cabin grade

Available

from $4,464

$279 / night

per person · incl. taxes & fees

Suite

from $3,554

$222 / night

Fare rows

Signature Suite

Cabin grade

Available

from $3,554

$222 / night

per person · incl. taxes & fees

Neptune Suite

Cabin grade

Available

from $5,254

$328 / night

per person · incl. taxes & fees

Signature Suite

Cabin grade

Available

from $5,394

$337 / night

per person · incl. taxes & fees

Signature Suite

Cabin grade

Available

from $5,694

$355 / night

per person · incl. taxes & fees

Signature Suite

Cabin grade

Available

from $5,994

$374 / night

per person · incl. taxes & fees

Neptune Suite

Cabin grade

Available

from $7,094

$443 / night

per person · incl. taxes & fees

Neptune Suite

Cabin grade

Available

from $7,694

$480 / night

per person · incl. taxes & fees

Neptune Suite

Cabin grade

Available

from $8,294

$518 / night

per person · incl. taxes & fees

Prices verified Sep 9, 2026

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The journey

16 nights, in order

Fort Lauderdale (Port Everglades)

Day 1 Nov 18, 2026

Fort Lauderdale (Port Everglades)

With its heady mix of Creole culture and French sophistication, there is more than a pinch of je ne sais quoi in Fort de France.

Explore Fort Lauderdale (Port Everglades)

Day by day

The full itinerary

20 scheduled calls
Oosterdam

Your ship

Oosterdam

Oosterdam, a Vista-class ship, recently emerged from dry dock with exciting updates—including completely refreshed suites and new lounge, dining and entertainment venues, such as Music Walk, with Lincoln Center Stage, B.B. King’s Blues Club and Billboard Onboard. Guests can choose from among delectable specialty restaurants, hone culinary skills with EXC Port to Table and thrill to BBC Earth Experiences.

5★ 82,305 GT 1,916 Passengers Built 2003
Oosterdam ship guide Search cruises on Oosterdam

Deck plans

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from $1,804 pp

via CruiseDirect

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