San Antonio, Chile cruise port guide
Nestled between the Andes and the Pacific Ocean, energetic Santiago de Chile offers surprising discoveries with its renovated arts scene, expansive museums and noteworthy restaurants you won’t want to miss. Take in the outstanding views of this cosmopolitan capital by biking or hiking up one of its many gorgeous hills. Visit the Plaza de Armas – Santiago’s Original City Center – where you’ll be able to see a wealth of historical buildings and grand architecture. Or get a glimpse into the private and professional life of the poet and Nobel Prize winner Pablo Neruda by visiting one of his homes, all three of which have been converted into museums.
About San Antonio, Chile
San Antonio is a port city in Chile's Valparaíso Region, located approximately 100 km west of Santiago along the Pacific coast. It serves as a major commercial port and a gateway port for cruise passengers accessing Santiago and the wine regions of central Chile. The port offers access to world-class vineyards and the cosmopolitan capital, as well as the nearby beach resort of Cartagena.
Santiago excursions are the most popular option, covering the Plaza de Armas, La Moneda palace, and Bellavista neighborhood. Wine tours to Casablanca Valley wineries are another draw. Valparaíso and Viña del Mar offer colorful street art, cable car funiculars, and beach promenades.
Quick facts
Cruises visiting San Antonio, Chile
Prices per person · incl. taxes & fees.
Sailing soonest
Exploring Galápagos
National Geographic Endeavour II · South America · 9 nights
from $16,116
$1,790 / night
Exploring Galápagos
National Geographic Gemini · South America · 9 nights
from $20,013
$2,223 / night
Exploring Galápagos
National Geographic Endeavour II · South America · 9 nights
from $12,926
$1,436 / night
Exploring Galápagos
National Geographic Gemini · South America · 9 nights
from $18,424
$2,047 / night
Exploring Galápagos
National Geographic Endeavour II · South America · 9 nights
from $14,218
$1,579 / night
Exploring Galápagos
National Geographic Gemini · South America · 9 nights
from $17,551
$1,950 / night
Showing the 20 least-expensive of 260 sailings.
Showing 260 San Antonio, Chile cruises
Open in full search| View | Ship image | Cruise line | Line / Ship | Departs | Nights | From |
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Jan 4, 2027 | 15 |
from $1,000 $66 / night |
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Jan 19, 2027 | 14 |
from $1,241 $88 / night |
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Mar 10, 2027 | 8 |
from $1,659 $207 / night |
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Dec 7, 2026 | 15 |
from $1,935 $129 / night |
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Dec 8, 2026 | 14 |
from $2,149 $153 / night |
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Dec 22, 2026 | 15 |
from $2,215 $147 / night |
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Feb 28, 2027 | 19 |
from $2,779 $146 / night |
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Dec 6, 2027 | 15 |
from $2,982 $198 / night |
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Feb 16, 2028 | 15 |
from $3,009 $200 / night |
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Nov 17, 2027 | 15 |
from $3,034 $202 / night |
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Jan 2, 2028 | 15 |
from $3,069 $204 / night |
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Feb 1, 2028 | 15 |
from $3,189 $212 / night |
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Jan 17, 2028 | 15 |
from $3,209 $213 / night |
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Dec 2, 2027 | 15 |
from $3,244 $216 / night |
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Nov 2, 2027 | 15 |
from $3,249 $216 / night |
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Nov 21, 2027 | 15 |
from $3,307 $220 / night |
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Mar 2, 2028 | 15 |
from $3,389 $225 / night |
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Nov 18, 2026 | 16 |
from $3,404 $212 / night |
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Feb 21, 2028 | 14 |
from $3,494 $249 / night |
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Mar 24, 2027 | 16 |
from $3,569 $223 / night |
