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14-night Panama Canal cruise: Miami, Florida to Panama City on Seven Seas Grandeur

The Exotic Coasts & Casco Viejo - Miami to Panama City is a 14-night Panama Canal cruise aboard Seven Seas Grandeur, operated by Regent Seven Seas Cruises. Departing Miami, Florida on February 23, 2027 and arriving in Panama City on March 9, 2027, the voyage visits 11 ports including Puerto Costa Maya, Harvest Caye, Roatan, Bay Islands. Fares start from $10,249 per person.

Length
14 nights
Departs
Feb 23, 2027
Returns
Mar 9, 2027
Ports of call
11
Days at sea
4

Voyage code GRA270223

Miami, Florida

14 nights · Panama Canal

from $10,249 pp

via CruiseDirect

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Why this route stands out

A closer look at the journey

Miami, Florida

Miami is called the gateway to the Americas, and it’s indeed a very glamourous global city to explore at the start or end of an MSC Caribbean and Antilles cruise. Home to many cultures, the city of Miami sizzles with flavours from the Americas, beginning with Cuba and the Little Havana neighbourhood - one of the most historically significant places, while Wynwood is famous for its wall art and Puerto Rican history. Across Biscayne Bay lies the city of Miami Beach, home to the world-famous South Beach. An MSC-arranged guided private tour opens up a world of possibilities for you: enjoy the beach, take in the city’s Art Deco architecture and enjoy a drink on legendary Ocean Drive, where you can people watch, and perhaps spot a celebrity. If time permits, take a stroll on artsy Lincoln Road packed with street side cafes and shops. Facing the MSC Cruises port in downtown Miami is Bayside Marketplace - a lively commercial centre that is a staging area for boat tours of Miami. Seeing the city from the water, with its impressive skyline and waterfront mansions, is an experience in itself. The downtown area also boasts the dazzling Performing Arts Centre, the Museum of Science, the Pérez Art Museum Miami (known as the PAMM), scenic Bayfront Park and the arena where the 3-time NBA champion Miami Heat basketball team plays. Miami is renowned for its shopping. Hop on a tour to see the major city sights followed by retail therapy at one of Miami's largest and newest shopping malls: Dolphin Mall. With more than 240 retail outlets, you’re bound to need a bit of room in your luggage for your purchases. Luckily, there are several luggage stores at the mall to fill that need. Head west past the city into untamed wilderness on an MSC excursion into the Everglades. At this national park where water is the central feature, unlike any other in North America, nature enthusiasts can hop on an airboat tour through the swampland and waterways to spot alligators and a variety of birds.

Puerto Costa Maya

Puerto Costa Maya, where the Caribbean and Antilles MSC cruise ships dock, is out of sight north of Mahahual, but its influence is felt on cruise-ship days, when the village springs to life with souvenir stands and jet-ski rentals along the slick seafront promenade, an extremely miniature version of Playa del Carmen. The two towns in the area, Mahahual and the smaller Xcalak, were hit hard by Hurricane Dean in 2007. Mahahual was rebuilt, but Xcalak is still quite battered. On an MSC Caribbean and Antilles cruise you will typically stay around Mahahual, while divers and anglers head south to Xcalak. If you stop for only one ancient site in the Río Bec area, Kohunlich is your best excursion choice. The ruins, seldom visited by anyone other than enormous butterflies and wild parrots, are beautifully situated, peering out above the treetops. The buildings date from the late pre-Classic to the Classic periods (100–900 AD) and the majority are in the Río Bec architectural style. Foliage has reclaimed most of them, except for the Templo de los Mascarones, which is named after the five 2m-high stucco masks that decorate its facade. Disturbing enough now, these wide-eyed, open-mouthed images of the sun god, Kinich Ahau, once stared out from a background of smooth, bright-red-painted stucco. Also look for an elite residential area called the 27 Escalones, worth the detour to see the great views over the jungle canopy from the cliff edge on which it is built. Set in a drier area with sparse trees, these two neighbouring ruins are an interesting contrast to Kohunlich. Kinichná’s hulking pyramid, built in metre-high stones, layer upon layer by successive leaders, barely clears the trees, but you can look over the surrounding terrain (and spot a glimpse of the Dzibanché ancient Maya archaeological site), now broken into farmland.

Harvest Caye

Featuring an enchanting range of environments such as tropical rainforests, marshes and coral reefs, Harvest Caye offers both relaxation and adventure amid lush landscapes. This 75-acre paradise invites you to explore its incredibly biodiverse surroundings, witnessing exotic wildlife or perhaps discovering the world’s second largest coral reef. Gain insight into the region’s Mayan and Garifuna roots, discover traditional arts and traditions at the local artisans’ village or simply soak up the abundant Belizean sunshine and relax.

Price tracking

Today’s fare, in context

Price history

Cheaper than 78%
30 days
Fare details

Fare details

Per person · taxes & fees included
Current fares
Verified 5 hours ago
Suite
$10,249
Tracked range
157 days
Price history by cabin type
CabinCurrentLowestHighest
Suite $10,249 $9,099 on Jul 8 $10,849 on Apr 24
Cabin grades
15 total
Penthouse SuiteSuite · A
Penthouse SuiteSuite · B
Penthouse SuiteSuite · C
Concierge SuiteSuite · D
Concierge SuiteSuite · E
Serenity SuiteSuite · F1
Serenity SuiteSuite · F2
Deluxe Veranda SuiteSuite · G1
Deluxe Veranda SuiteSuite · G2
Grandeur SuiteSuite · GN
Grand SuiteSuite · GS
Veranda SuiteSuite · H
Regent SuiteSuite · RS
Signature SuiteSuite · SG
Seven Seas SuiteSuite · SS

○ = last seen (sold out or delisted). · Verified 5 hours ago.

Lowest fares with no residency, age, or service requirement — verify eligibility at booking. How our pricing works

Current prices

Per person · 2 guests · incl. taxes & fees

Inside

Not available

Oceanview

Not available

Balcony

Not available

Suite

from $10,249

$732 / night

Fare rows

Deluxe Veranda Suite

Cabin grade

Available

from $10,249

$732 / night

per person · incl. taxes & fees

Deluxe Veranda Suite

Cabin grade

Available

from $10,299

$735 / night

per person · incl. taxes & fees

Serenity Suite

Cabin grade

Available

from $11,049

$789 / night

per person · incl. taxes & fees

Deluxe Veranda Suite

Cabin grade

Available

from $13,349

$953 / night

per person · incl. taxes & fees

Deluxe Veranda Suite

Cabin grade

Available

from $13,349

$953 / night

per person · incl. taxes & fees

Deluxe Veranda Suite

Cabin grade

Available

from $13,399

$957 / night

per person · incl. taxes & fees

Deluxe Veranda Suite

Cabin grade

Available

from $13,399

$957 / night

per person · incl. taxes & fees

Serenity Suite

Cabin grade

Available

from $14,149

$1,010 / night

per person · incl. taxes & fees

Penthouse Suite

Cabin grade

Available

from $16,809

$1,200 / night

per person · incl. taxes & fees

Penthouse Suite

Cabin grade

Available

from $17,009

$1,214 / night

per person · incl. taxes & fees

Penthouse Suite

Cabin grade

Available

from $17,159

$1,225 / night

per person · incl. taxes & fees

Penthouse Suite

Cabin grade

Available

from $20,099

$1,435 / night

per person · incl. taxes & fees

Penthouse Suite

Cabin grade

Available

from $20,299

$1,449 / night

per person · incl. taxes & fees

Penthouse Suite

Cabin grade

Available

from $20,449

$1,460 / night

per person · incl. taxes & fees

Grandeur Suite

Cabin grade

Available

from $22,609

$1,614 / night

per person · incl. taxes & fees

Grandeur Suite

Cabin grade

Available

from $25,899

$1,849 / night

per person · incl. taxes & fees

Prices verified Sep 1, 2026

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The journey

14 nights, in order

Miami, Florida

Day 1 Feb 23, 2027

Miami, Florida

Miami is called the gateway to the Americas, and it’s indeed a very glamourous global city to explore at the start or end of an MSC Caribbean and Antilles cruise.

Explore Miami, Florida

Day by day

The full itinerary

16 scheduled calls
Seven Seas Grandeur

Your ship

Seven Seas Grandeur

For more than thirty years, we have delivered unrivaled experiences throughout the world. All the while, we have been listening to our guests, evolving our services and continually refining each element of the Regent experience. Embrace the freedom enjoyed through the most all-inclusive luxury experience on the Seven Seas aboard a ship that elevates the pinnacle of ocean cruising to new heights. Inspired by the past and stunningly reimagined for the future, Seven Seas Grandeur™ will exemplify our heritage of perfection with unrivaled space, unparalleled service, exceptional cuisine and transformative experiences that will begin the moment you step aboard.

6★ 55,498 GT 746 Passengers Built 2021
Seven Seas Grandeur ship guide Search cruises on Seven Seas Grandeur

Deck plans

Deck plan for Deck 4

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More ways to take this journey

Fly-cruise options

Fly-cruise package options
Airport Price pp Included
ABQ $15,279.00 Extra
ALB $15,249.00 Extra
ATL $15,189.00 Extra
AUS $15,239.00 Extra
AVL $15,229.00 Extra
BDL $15,249.00 Extra
BFL $15,249.00 Extra
BHM $15,249.00 Extra
BIL $15,259.00 Extra
BNA $15,249.00 Extra
BOI $15,279.00 Extra
BOS $15,149.00 Extra
BUF $15,249.00 Extra
BWI $15,159.00 Extra
CHA $15,239.00 Extra
CHS $15,229.00 Extra
CID $15,239.00 Extra
CLE $15,249.00 Extra
CLT $15,249.00 Extra
CMH $15,249.00 Extra
COS $15,259.00 Extra
CVG $15,249.00 Extra
DCA $15,149.00 Extra
DEN $15,199.00 Extra
DFW $15,109.00 Extra
DSM $15,239.00 Extra
DTW $15,189.00 Extra
ELP $15,279.00 Extra
EUG $15,249.00 Extra
EWR $15,049.00 Extra
FAR $15,239.00 Extra
FAT $15,269.00 Extra
FSD $15,239.00 Extra
GEG $15,249.00 Extra
GRR $15,249.00 Extra
GSO $15,269.00 Extra
GSP $15,229.00 Extra
GTF $15,279.00 Extra
HNL $15,269.00 Extra
HSV $15,249.00 Extra
IAD $15,149.00 Extra
IAH $15,169.00 Extra
ICT $15,239.00 Extra
ILM $15,229.00 Extra
IND $15,249.00 Extra
JAN $15,249.00 Extra
JAX $15,289.00 Extra
JFK $15,049.00 Extra
LAS $15,279.00 Extra
LAX $15,249.00 Extra
LBB $15,239.00 Extra
LEX $15,239.00 Extra
LGA $15,049.00 Extra
LIT $15,239.00 Extra
MAF $15,239.00 Extra
MCI $15,239.00 Extra
MCO $15,139.00 Extra
MDW $15,149.00 Extra
MEM $15,249.00 Extra
MKE $15,239.00 Extra
MOB $15,249.00 Extra
MSN $15,239.00 Extra
MSP $15,219.00 Extra
MSY $15,239.00 Extra
MYR $15,229.00 Extra
OKC $15,239.00 Extra
OMA $15,239.00 Extra
ORD $15,149.00 Extra
ORF $15,229.00 Extra
PDX $15,269.00 Extra
PHL $15,249.00 Extra
PHX $15,209.00 Extra
PIA $15,239.00 Extra
PIT $15,249.00 Extra
PSP $15,269.00 Extra
PVD $15,249.00 Extra
PWM $15,249.00 Extra
RDU $15,229.00 Extra
RIC $15,229.00 Extra
RNO $15,279.00 Extra
ROC $15,249.00 Extra
SAN $15,239.00 Extra
SAT $15,269.00 Extra
SAV $15,259.00 Extra
SBA $15,269.00 Extra
SDF $15,249.00 Extra
SEA $15,209.00 Extra
SFO $15,229.00 Extra
SGF $15,239.00 Extra
SHV $15,239.00 Extra
SLC $15,279.00 Extra
SMF $15,269.00 Extra
SNA $15,259.00 Extra
STL $15,239.00 Extra
SYR $15,249.00 Extra
TPA $15,149.00 Extra
TUL $15,239.00 Extra
TUS $15,279.00 Extra
TYS $15,249.00 Extra
XNA $15,239.00 Extra
YEG $15,279.00 Extra
YOW $15,249.00 Extra
YUL $15,219.00 Extra
YVR $15,259.00 Extra
YYC $15,279.00 Extra
YYJ $15,249.00 Extra
YYZ $15,179.00 Extra

from $10,249 pp

via CruiseDirect

Book with CruiseDirect

Book direct with Regent Seven Seas Cruises we may earn a commission