15-night North America cruise: Miami, Florida to Los Angeles, CA on Vista
The Miami To Los Angeles is a 15-night North America cruise aboard Vista, operated by Oceania Cruises. Departing Miami, Florida on January 6, 2027 and arriving in Los Angeles, CA on January 21, 2027, the voyage visits 9 ports including George Town, Cayman Islands, Cartagena, Colombia, Panama Canal. Fares start from $7,349 per person.
Fixed editorial images from the places on this itinerary. They stay stable each time you return to this sailing.
Miami, Florida
Miami is called the gateway to the Americas, and it’s indeed a very glamourous global city to explore at the start or end of an MSC Caribbean and Antilles cruise. Home to many cultures, the city of Miami sizzles with flavours from the Americas, beginning with Cuba and the Little Havana neighbourhood - one of the most historically significant places, while Wynwood is famous for its wall art and Puerto Rican history.
Across Biscayne Bay lies the city of Miami Beach, home to the world-famous South Beach. An MSC-arranged guided private tour opens up a world of possibilities for you: enjoy the beach, take in the city’s Art Deco architecture and enjoy a drink on legendary Ocean Drive, where you can people watch, and perhaps spot a celebrity. If time permits, take a stroll on artsy Lincoln Road packed with street side cafes and shops.
Facing the MSC Cruises port in downtown Miami is Bayside Marketplace - a lively commercial centre that is a staging area for boat tours of Miami. Seeing the city from the water, with its impressive skyline and waterfront mansions, is an experience in itself. The downtown area also boasts the dazzling Performing Arts Centre, the Museum of Science, the Pérez Art Museum Miami (known as the PAMM), scenic Bayfront Park and the arena where the 3-time NBA champion Miami Heat basketball team plays.
Miami is renowned for its shopping. Hop on a tour to see the major city sights followed by retail therapy at one of Miami's largest and newest shopping malls: Dolphin Mall. With more than 240 retail outlets, you’re bound to need a bit of room in your luggage for your purchases. Luckily, there are several luggage stores at the mall to fill that need.
Head west past the city into untamed wilderness on an MSC excursion into the Everglades. At this national park where water is the central feature, unlike any other in North America, nature enthusiasts can hop on an airboat tour through the swampland and waterways to spot alligators and a variety of birds.
George Town, Cayman Islands
Christopher Columbus called the Cayman Islands, with their tranquil blue waters, "Las Tortugas" for its abundance of turtles. Located between Cuba and Jamaica, the Cayman Islands are comprised of three Caribbean islands: Grand Cayman, Little Cayman and Cayman Brac.
Beautiful landscapes, bountiful wildlife and colourful streets embody this British Overseas Territory, with George Town, its capital, located on Grand Cayman, the largest and most populous island.
When you arrive in George Town on an MSC Caribbean and Antilles cruise, you’ll discover that wildlife conservation is at the core of Grand Cayman’s offerings. For the chance of a lifetime to swim, feed and interact with stingrays, book an MSC excursion to Stingray City, where you’ll get an up-close experience with Cayman’s most graceful marine creatures. On yet another MSC excursion to the Cayman Turtle Centre, encounter the green turtles that return each and every year to lay their eggs on one of the beaches, visit the turtle hatchery, snorkel alongside yearlings in the Turtle Lagoon and meet the island’s endangered blue iguanas.
For a special experience, ride horses bareback into the Caribbean Sea at Barker’s National Park on an exclusive Martha Stewart excursion curated just for MSC Cruises, followed by lunch at Vivo café, a spot beloved for its mostly vegan cuisine, with organic ingredients sourced straight from local farms.
To learn about Cayman’s past and culture, explore Cayman Heritage House and visit the sumptuous Government House, the governor's residence built in 1964 located in front of Seven Mile Beach, one of the most prestigious beaches of Grand Cayman, in the heart of West Bay.
Shopaholics will also delight in this destination. The Cayman Islands are entirely duty free. You just have to choose what catches your fancy among the myriad of watches, liqueurs, jewellery and porcelain on offer.
Cartagena, Colombia
Cobbled streets, balconies overflowing with blooming bougainvillea and pastel-coloured buildings lining elegant plazas make Cartagena in Colombia one of the Caribbean's most photogenic cities, and a memorable stop on an MSC Caribbean and Antilles cruise.
Founded in 1533, this Spanish colonial city, a UNESCO World Heritage Site, is steeped in history. Its location made it a popular target for plunderers and English pirates, and arguably features the most impressive collection of forts in the Caribbean. Today the city is eager to share its treasures with modern visitors. Magnificent colonial structures such as the 16th-century Santa Catalina Cathedral, with its striking stuccoes and dome tower, and the three-arch clock gate, the Torre del Reloj, are just two of the many landmarks of this enchanting city dotted with many squares and sidewalk cafés.
A wonderful photo stop on our Cartagena City MSC excursion is the San Felipe de Barajas fortress, a marvel of colonial Spanish military engineering. Its construction began in 1536. Slaves la-boured for more than 120 years to erect this fortress - built on high ground with dominating ap-proaches to the city by land and sea to fend off pirates - and its network of tunnels.
On yet another MSC excursion, enrich your palate as you learn about the rich aromas and flavours of Colombian coffee. Introduced by the Jesuits in 1723, coffee quickly became a key crop in Colombia, which is now one of the top producers of Arabica coffee in the world.
Colombia is also the world’s top producer of emeralds. If jewellery and gems fascinate you, learn all about these green precious stones and make your own emerald-studded jewellery in sterling silver during a hands-on MSC excursion that guides you step-by-step.
And you don’t need to go far to explore nature. An MSC excursion takes you by canoe through mangrove tunnels to Ciénaga de la Virgen, where you can witness a diversity of birds from king-fishers and white herons to pelicans and pink-feathered roseate spoonbills.
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Follow the entire sailing from its first day to its last, with the route and schedule in one view.
Day 1·Jan 6, 2027
Miami, Florida
Miami is called the gateway to the Americas, and it’s indeed a very glamourous global city to explore at the start or end of an MSC Caribbean and Antilles cruise.
Vista is your world from a new perspective and honors our passion for serving The Finest Cuisine at Sea with imaginative new dining concepts and the debut of new epicurean delights. Be among the first to experience Ember, the newest addition to the Oceania Cruises family of restaurants, and Aquamar, Kitchen, offering an array of indulgent, wellness-inspired dishes. Enjoy unforgettable dining experiences at treasured and iconic dining venues that have been elevated to new heights, from the refined elegance of The Grand Dining Room to the ultimate steakhouse experience at Polo Grill. Join us as we embark on the next chapter of Oceania Cruises’ culinary story.
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