14-night Caribbean cruise: Panama City to Miami, Florida on Seven Seas Grandeur
The Panama City to Miami, FL is a 14-night Caribbean cruise aboard Seven Seas Grandeur, operated by Regent Seven Seas Cruises. Departing Panama City on March 31, 2027 and arriving in Miami, Florida on April 14, 2027, the voyage visits 12 ports including Panama Canal, Cartagena, Colombia, Santa Marta. Fares start from $9,749 per person.
You probably can’t think of Panama City without conjuring images of the Panama Canal. But nearly 400 years before the Panama Canal opened its locks, Panama City was making its mark. From the vestiges of the original settlement to the modern skyscrapers, experience the history and culture of one of the Pacific Coast’s oldest continuously inhabited European settlements. After exploring the bustling local markets in search of fresh fish or artisan handicrafts, admire the restored Spanish Colonial architecture in Casco Viejo. Or you can head to the Miraflores Locks and watch one of the modern world’s most heroic feats of engineering in action.
Panama Canal
Panama is synonymous with the Panama Canal. While Panama connects Central America to South America, the Panama Canal, which opened in 1914, connects the Caribbean Sea with the Pacific Ocean. The channel reduces shipping time and currently connects 160 countries and 1,700 ports around the world. Hailed as an engineering marvel, the artificial waterway with its elaborate lock system is one of the greatest achievements of the 20th century.
Arriving on an MSC Caribbean and Antilles cruise into Colón, Panama’s gateway city, you’ll encounter the irresistible juxtaposition of the ancient and modern, the artificial and natural, as enormous computerized container ships transiting the canal slice through primeval rainforests teeming with fluorescent frogs and elusive wild cats.
Book an MSC excursion to hop on a ferry that will take you along the length of the Panama Canal, through lakes and locks and past the Centennial and Americas bridges. Finally, you will arrive at Pacific port at the entrance to the Panama Canal, and then enjoy a 90-minute bus ride back to your ship.
Cartagena, Colombia
Cobbled streets, balconies overflowing with blooming bougainvillea and pastel-coloured buildings lining elegant plazas make Cartagena in Colombia one of the Caribbean's most photogenic cities, and a memorable stop on an MSC Caribbean and Antilles cruise.
Founded in 1533, this Spanish colonial city, a UNESCO World Heritage Site, is steeped in history. Its location made it a popular target for plunderers and English pirates, and arguably features the most impressive collection of forts in the Caribbean. Today the city is eager to share its treasures with modern visitors. Magnificent colonial structures such as the 16th-century Santa Catalina Cathedral, with its striking stuccoes and dome tower, and the three-arch clock gate, the Torre del Reloj, are just two of the many landmarks of this enchanting city dotted with many squares and sidewalk cafés.
A wonderful photo stop on our Cartagena City MSC excursion is the San Felipe de Barajas fortress, a marvel of colonial Spanish military engineering. Its construction began in 1536. Slaves la-boured for more than 120 years to erect this fortress - built on high ground with dominating ap-proaches to the city by land and sea to fend off pirates - and its network of tunnels.
On yet another MSC excursion, enrich your palate as you learn about the rich aromas and flavours of Colombian coffee. Introduced by the Jesuits in 1723, coffee quickly became a key crop in Colombia, which is now one of the top producers of Arabica coffee in the world.
Colombia is also the world’s top producer of emeralds. If jewellery and gems fascinate you, learn all about these green precious stones and make your own emerald-studded jewellery in sterling silver during a hands-on MSC excursion that guides you step-by-step.
And you don’t need to go far to explore nature. An MSC excursion takes you by canoe through mangrove tunnels to Ciénaga de la Virgen, where you can witness a diversity of birds from king-fishers and white herons to pelicans and pink-feathered roseate spoonbills.
For more than thirty years, we have delivered unrivaled experiences throughout the world. All the while, we have been listening to our guests, evolving our services and continually refining each element of the Regent experience. Embrace the freedom enjoyed through the most all-inclusive luxury experience on the Seven Seas aboard a ship that elevates the pinnacle of ocean cruising to new heights.
Inspired by the past and stunningly reimagined for the future, Seven Seas Grandeur™ will exemplify our heritage of perfection with unrivaled space, unparalleled service, exceptional cuisine and transformative experiences that will begin the moment you step aboard.
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