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12-night Caribbean cruise: Los Angeles, CA to Panama City on Seven Seas Prestige

The Los Angeles, CA to Panama City is a 12-night Caribbean cruise aboard Seven Seas Prestige, operated by Regent Seven Seas Cruises. Departing Los Angeles, CA on February 10, 2027 and arriving in Panama City on February 22, 2027, the voyage visits 7 ports including Cabo San Lucas, Mazatlan, Mexico, Acapulco. Fares start from $9,049 per person.

Length
12 nights
Departs
Feb 10, 2027
Returns
Feb 22, 2027
Ports of call
7
Days at sea
6

Voyage code PRT270210

Los Angeles, CA

12 nights · Caribbean

from $9,049 pp

via CruiseDirect

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Why this route stands out

A closer look at the journey

Los Angeles, CA

Los Angeles is a huge city with a thousand facets and attractions, one of the most stimulating urban centers that can be visited ever. Your MSC World Cruise will take you on the discovery of a place that has no equal, with its golden Pacific beaches, theme parks from the film world and walks down Sunset Boulevard with the Walk of Fame and its various museums. Los Angeles is perfect for those who enjoy shopping, entertainment and relaxation for a truly unforgettable vacation. What will the main stops on your MSC Cruises excursion be? No doubt a visit to Beverly Hills, the exclusive center of fashion and beauty where you can admire a multitude of homes in full California style. This residential area is famous for its proximity to Hollywood and for being home to many movie stars, as well as for hosting some of the most beautiful restaurants, shops and hotels in the world. And how could you not visit impressive Malibu, the seaside town in the west of the coast of Los Angeles. The beaches here are the best for swimming and sunbathing, thanks to the beautiful landscape that accompanies them, the jagged mountains of the Santa Monica Mountains National Recreation Area. Not far from Malibu is Santa Monica, another glittering attraction known for its famous Luna Park that was built on the pier in 1909. This bustling city is also popular for its climate, the beauty of the coast, the efficiency of its services, its clubs, shops and lively pedestrian streets that are full of street artists who have made Santa Monica one of the main destinations of Los Angeles. With MSC Cruises, you will have the chance to see one of the most beautiful cities in the world with your own eyes.

Cabo San Lucas

Found at the tip of Baja California, Cabo San Lucas is where the desert meets the ocean. Although it has received a makeover of modern Americana in recent years, this place is still a world away from everywhere else in Mexico. A trip to Cabo (the San Lucas is optional) will not leave you disappointed. With swaying palm trees, turquoise seas and long ribbons of white sand, this is a resort that ticks every box: great food, great nightlight which equal great times – for some. Others may prefer to scratch the surface just a bit deeper and travel along the peninsula that is known for its dramatic scenery of desert terrain and rugged coastline marked by many unusual formations. The sweeping views of the bay are simply sensational. A quick turn inward takes you to San Jose del Cabo, Cabo San Lucas’ older and more grown up sister. Offering a very much calmer and much more authentic atmosphere, just half an hour along the coast leaves you in its desert terrain, and leaves a very different impression from the lively beachfront bars and cafes of San Lucas. Perhaps one of the most stunning ways to see Cabo though is from the water. With the Arco de Cabo San Lucas featuring highly on many must-see lists, a trip around the bay is a must. The braver among you might also like to indulge their inner adrenalin junkie and swim with whale sharks – a memorable and totally risk-free experience if there ever was one. End your day of sightseeing with a fabulous sunset, a (tequila) sunrise in hand, watching the fishermen come home from their adventures.

Acapulco

Acapulco, nicknamed "Pearl of the Pacific," is Mexico's most glamorous pacific resort. Located on a deep, semi-circular bay, Acapulco is located southwest of Mexico City. Few destinations can match its superb weather with an average of 360 days of sunshine per year and with temperatures comfortably in the 80s. Acapulco was important as a port city for Spanish galleons sailing between Spain and the Orient long before it was "discovered" as a vacation playground.

Price tracking

Today’s fare, in context

Price history

Cheaper than 100%
30 days
Fare details

Fare details

Per person · taxes & fees included
Current fares
Verified 26 minutes ago
Suite
$9,049
Tracked range
162 days
Price history by cabin type
CabinCurrentLowestHighest
Suite $9,049 $7,549 on May 28 $9,049 on Sep 2
Cabin grades
20 total
Penthouse SuiteSuite · A
Penthouse SuiteSuite · B
Penthouse SuiteSuite · C
Concierge SuiteSuite · D
Concierge SuiteSuite · E
Serenity SuiteSuite · F1
Serenity SuiteSuite · F2
Deluxe Veranda SuiteSuite · G
Grand SuiteSuite · GS
Deluxe Veranda SuiteSuite · H
Horizon Penthouse SuiteSuite · HP
SuiteSuite · I
Grand Loft SuiteSuite · LS
Prestige SuiteSuite · PS
Skyview Regent SuiteSuite · RS
Signature SuiteSuite · SG
Skyview Aura SuiteSuite · SKA
Skyview Luna SuiteSuite · SKB
Skyview Sola SuiteSuite · SKC
Seven Seas SuiteSuite · SS

○ = last seen (sold out or delisted). · Verified 26 minutes ago.

Lowest fares with no residency, age, or service requirement — verify eligibility at booking. How our pricing works

Current prices

Per person · 2 guests · incl. taxes & fees

Inside

Not available

Oceanview

Not available

Balcony

Not available

Suite

from $9,049

$754 / night

Fare rows

Serenity Suite

Cabin grade

Available

from $9,049

$754 / night

per person · incl. taxes & fees

Concierge Suite

Cabin grade

Available

from $9,599

$799 / night

per person · incl. taxes & fees

Concierge Suite

Cabin grade

Available

from $9,949

$829 / night

per person · incl. taxes & fees

Penthouse Suite

Cabin grade

Available

from $10,299

$858 / night

per person · incl. taxes & fees

Penthouse Suite

Cabin grade

Available

from $10,549

$879 / night

per person · incl. taxes & fees

Penthouse Suite

Cabin grade

Available

from $10,849

$904 / night

per person · incl. taxes & fees

Serenity Suite

Cabin grade

Available

from $12,049

$1,004 / night

per person · incl. taxes & fees

Concierge Suite

Cabin grade

Available

from $12,749

$1,062 / night

per person · incl. taxes & fees

Concierge Suite

Cabin grade

Available

from $13,099

$1,091 / night

per person · incl. taxes & fees

Penthouse Suite

Cabin grade

Available

from $13,449

$1,120 / night

per person · incl. taxes & fees

Penthouse Suite

Cabin grade

Available

from $13,699

$1,141 / night

per person · incl. taxes & fees

Penthouse Suite

Cabin grade

Available

from $13,999

$1,166 / night

per person · incl. taxes & fees

Seven Seas Suite

Cabin grade

Available

from $16,349

$1,362 / night

per person · incl. taxes & fees

Prestige Suite

Cabin grade

Available

from $18,999

$1,583 / night

per person · incl. taxes & fees

Seven Seas Suite

Cabin grade

Available

from $19,499

$1,624 / night

per person · incl. taxes & fees

Grand Suite

Cabin grade

Available

from $21,699

$1,808 / night

per person · incl. taxes & fees

Grand Loft Suite

Cabin grade

Available

from $21,749

$1,812 / night

per person · incl. taxes & fees

Prestige Suite

Cabin grade

Available

from $22,149

$1,845 / night

per person · incl. taxes & fees

Grand Suite

Cabin grade

Available

from $24,849

$2,070 / night

per person · incl. taxes & fees

Grand Loft Suite

Cabin grade

Available

from $24,899

$2,074 / night

per person · incl. taxes & fees

Prices verified Sep 2, 2026

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The journey

12 nights, in order

Los Angeles, CA

Day 1 Feb 10, 2027

Los Angeles, CA

Los Angeles is a huge city with a thousand facets and attractions, one of the most stimulating urban centers that can be visited ever.

Explore Los Angeles, CA

Day by day

The full itinerary

13 scheduled calls
Seven Seas Prestige

Your ship

Seven Seas Prestige

Seven Seas Prestige will be the first of two Prestige-Class ships, the second of which will be launched in 2029. The new ship class will introduce brand new accommodation categories, including a reimagination of the palatial Regent Suite, plus new dining experiences, all of which will be revealed at a later date. These new features will further enhance The Most Inclusive Luxury Experience® that Regent is known for with inclusions such as flights and transfers, gourmet cuisine in a range of specialty restaurants and al-fresco dining venues, fine wines and spirits, entertainment, unlimited internet access, free valet laundry, gratuities, one-night, pre-cruise hotel packages for guests staying in Concierge-level suites and higher and more.

6★ 77,000 GT 850 Passengers
Seven Seas Prestige ship guide Search cruises on Seven Seas Prestige

Deck plans

Deck plan for Deck 4

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More ways to take this journey

Fly-cruise options

Fly-cruise package options
Airport Price pp Included
ABQ $24,439.00 Extra
ALB $24,439.00 Extra
ATL $24,439.00 Extra
AUS $24,439.00 Extra
AVL $24,439.00 Extra
BDL $24,439.00 Extra
BFL $24,439.00 Extra
BHM $24,439.00 Extra
BIL $24,439.00 Extra
BNA $24,439.00 Extra
BOI $24,439.00 Extra
BOS $24,439.00 Extra
BUF $24,439.00 Extra
BWI $24,439.00 Extra
CHA $24,439.00 Extra
CHS $24,439.00 Extra
CID $24,439.00 Extra
CLE $24,439.00 Extra
CLT $24,439.00 Extra
CMH $24,439.00 Extra
COS $24,439.00 Extra
CVG $24,439.00 Extra
DCA $24,439.00 Extra
DEN $24,439.00 Extra
DFW $24,439.00 Extra
DSM $24,439.00 Extra
DTW $24,439.00 Extra
ELP $24,439.00 Extra
EUG $24,439.00 Extra
EWR $24,439.00 Extra
FAR $24,439.00 Extra
FAT $24,439.00 Extra
FLL $24,439.00 Extra
FSD $24,439.00 Extra
GEG $24,439.00 Extra
GRR $24,439.00 Extra
GSO $24,439.00 Extra
GSP $24,439.00 Extra
GTF $24,439.00 Extra
HNL $24,439.00 Extra
HSV $24,439.00 Extra
IAD $24,439.00 Extra
IAH $24,439.00 Extra
ICT $24,439.00 Extra
ILM $24,439.00 Extra
IND $24,439.00 Extra
JAN $24,439.00 Extra
JAX $24,439.00 Extra
JFK $24,439.00 Extra
LAS $24,439.00 Extra
LBB $24,439.00 Extra
LEX $24,439.00 Extra
LGA $24,439.00 Extra
LIT $24,439.00 Extra
MAF $24,439.00 Extra
MCI $24,439.00 Extra
MCO $24,439.00 Extra
MDW $24,439.00 Extra
MEM $24,439.00 Extra
MIA $24,439.00 Extra
MKE $24,439.00 Extra
MOB $24,439.00 Extra
MSN $24,439.00 Extra
MSP $24,439.00 Extra
MSY $24,439.00 Extra
MYR $24,439.00 Extra
OKC $24,439.00 Extra
OMA $24,439.00 Extra
ORD $24,439.00 Extra
ORF $24,439.00 Extra
PBI $24,439.00 Extra
PDX $24,439.00 Extra
PHL $24,439.00 Extra
PHX $24,439.00 Extra
PIA $24,439.00 Extra
PIT $24,439.00 Extra
PSP $24,439.00 Extra
PVD $24,439.00 Extra
PWM $24,439.00 Extra
RDU $24,439.00 Extra
RIC $24,439.00 Extra
RNO $24,439.00 Extra
ROC $24,439.00 Extra
RSW $24,439.00 Extra
SAN $24,439.00 Extra
SAT $24,439.00 Extra
SAV $24,439.00 Extra
SBA $24,439.00 Extra
SDF $24,439.00 Extra
SEA $24,439.00 Extra
SFO $24,439.00 Extra
SGF $24,439.00 Extra
SHV $24,439.00 Extra
SLC $24,439.00 Extra
SMF $24,439.00 Extra
STL $24,439.00 Extra
SYR $24,439.00 Extra
TPA $24,439.00 Extra
TUL $24,439.00 Extra
TUS $24,439.00 Extra
TYS $24,439.00 Extra
XNA $24,439.00 Extra
YEG $24,439.00 Extra
YOW $24,439.00 Extra
YUL $24,439.00 Extra
YVR $24,439.00 Extra
YYC $24,439.00 Extra
YYJ $24,439.00 Extra
YYZ $24,439.00 Extra

from $9,049 pp

via CruiseDirect

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