Miami to Panama City

The Miami to Panama City is a 10-night Caribbean cruise aboard Marina, operated by Oceania Cruises. Departing Miami, Florida on March 5, 2027, the voyage visits 8 ports. Fares start from $2,790 per person.

Length: 10 nights
Departs: Mar 5, 2027
Returns: Mar 15, 2027
Ports of call: 8
Days at sea: 3

from $2,790

$279 / night per person, incl. taxes & fees

Book with CruiseDirect

We may earn a commission

from $2,790 pp

via CruiseDirect

Book

we may earn a commission

Itinerary

Day 1 Mar 5, 2027 Miami, Florida Departs 17:00 Miami is called the gateway to the Americas, and it’s indeed a very glamourous global city to explore at the start or end of an MSC Caribbean and Antilles cruise. Home to many cultures, the city of Miami sizzles with flavours from the Americas, beginning with Cuba and the Little Havana neighbourhood - one of the most historically significant places, while Wynwood is famous for its wall art and Puerto Rican history. Across Biscayne Bay lies the city of Miami Beach, home to the world-famous South Beach. An MSC-arranged guided private tour opens up a world of possibilities for you: enjoy the beach, take in the city’s Art Deco architecture and enjoy a drink on legendary Ocean Drive, where you can people watch, and perhaps spot a celebrity. If time permits, take a stroll on artsy Lincoln Road packed with street side cafes and shops. Facing the MSC Cruises port in downtown Miami is Bayside Marketplace - a lively commercial centre that is a staging area for boat tours of Miami. Seeing the city from the water, with its impressive skyline and waterfront mansions, is an experience in itself. The downtown area also boasts the dazzling Performing Arts Centre, the Museum of Science, the Pérez Art Museum Miami (known as the PAMM), scenic Bayfront Park and the arena where the 3-time NBA champion Miami Heat basketball team plays. Miami is renowned for its shopping. Hop on a tour to see the major city sights followed by retail therapy at one of Miami's largest and newest shopping malls: Dolphin Mall. With more than 240 retail outlets, you’re bound to need a bit of room in your luggage for your purchases. Luckily, there are several luggage stores at the mall to fill that need. Head west past the city into untamed wilderness on an MSC excursion into the Everglades. At this national park where water is the central feature, unlike any other in North America, nature enthusiasts can hop on an airboat tour through the swampland and waterways to spot alligators and a variety of birds. Miami, Florida port guide Search cruises visiting Miami, Florida

Miami, Florida photo — Day 1 Mar 5, 2027 Miami, Florida Departs 17:00 Miami is called the gateway to the Americas, and it’s indeed a very glamourous global city to explore at the start or end of an MSC Caribbean and Antilles cruise. Home to many cultures, the city of Miami sizzles with flavours from the Americas, beginning with Cuba and the Little Havana neighbourhood - one of the most historically significant places, while Wynwood is famous for its wall art and Puerto Rican history. Across Biscayne Bay lies the city of Miami Beach, home to the world-famous South Beach. An MSC-arranged guided private tour opens up a world of possibilities for you: enjoy the beach, take in the city’s Art Deco architecture and enjoy a drink on legendary Ocean Drive, where you can people watch, and perhaps spot a celebrity. If time permits, take a stroll on artsy Lincoln Road packed with street side cafes and shops. Facing the MSC Cruises port in downtown Miami is Bayside Marketplace - a lively commercial centre that is a staging area for boat tours of Miami. Seeing the city from the water, with its impressive skyline and waterfront mansions, is an experience in itself. The downtown area also boasts the dazzling Performing Arts Centre, the Museum of Science, the Pérez Art Museum Miami (known as the PAMM), scenic Bayfront Park and the arena where the 3-time NBA champion Miami Heat basketball team plays. Miami is renowned for its shopping. Hop on a tour to see the major city sights followed by retail therapy at one of Miami's largest and newest shopping malls: Dolphin Mall. With more than 240 retail outlets, you’re bound to need a bit of room in your luggage for your purchases. Luckily, there are several luggage stores at the mall to fill that need. Head west past the city into untamed wilderness on an MSC excursion into the Everglades. At this national park where water is the central feature, unlike any other in North America, nature enthusiasts can hop on an airboat tour through the swampland and waterways to spot alligators and a variety of birds. Miami, Florida port guide Search cruises visiting Miami, Florida

Day 3 Mar 7, 2027 Cozumel 08:00 – 20:00 12.0 hrs ashore A forty-kilometre-long island directly off the coast from Playa del Carmen, Isla Cozumel is a renowned cruise-ship call: nearly every day, up to ten cruise ships dock at one of the island’s three dedicated piers, all just south of the only town, San Miguel. A holiday to Mexico with MSC Cruises will present you with restaurants, souvenir shops and jewellery stores, all along the malecón(Av Rafael Melgar) in downtown San Miguel. If you fancy a museum, the attractive Museo de la Isla de Cozumel has small displays of the flora, fauna and marine life of the island, as well as a good collection of Maya artefacts and old photos. If you’re not a diver, there’s a certain appeal in wandering the relaxed inland blocks of San Miguel, away from the piers, spotting Maya ruins and birds (the Maya called the island cuzamil – “land of the swallows”) in the dense forests and being the only person on the windswept eastern beaches. Midway across the island, San Gervasio is the only excavated Maya site on Cozumel. With several small temples connected by sacbeob, or long white roads, it was one of the many independent city-states that survived the fall of Chichén Itzá, flourishing between 1200 AD and 1650 AD. As part of a larger nature reserve the site is worth a visit for the numerous birds and butterflies you can spot early in the morning or late in the day. Another place to visit is Xcaret, a surprisingly pleasant theme park: it offers all the Yucatán’s attractions in one handy place, with a museum, a tropical aquarium, a “Maya village”, a beach, some small authentic ruins, pools and more than a kilometre of subterranean rivers down which you can swim, snorkel or float. On the other hand, neighbouring Xplor is dedicated to ziplines and other outdoor adventure. Cozumel port guide Search cruises visiting Cozumel

Cozumel photo — Day 3 Mar 7, 2027 Cozumel 08:00 – 20:00 12.0 hrs ashore A forty-kilometre-long island directly off the coast from Playa del Carmen, Isla Cozumel is a renowned cruise-ship call: nearly every day, up to ten cruise ships dock at one of the island’s three dedicated piers, all just south of the only town, San Miguel. A holiday to Mexico with MSC Cruises will present you with restaurants, souvenir shops and jewellery stores, all along the malecón(Av Rafael Melgar) in downtown San Miguel. If you fancy a museum, the attractive Museo de la Isla de Cozumel has small displays of the flora, fauna and marine life of the island, as well as a good collection of Maya artefacts and old photos. If you’re not a diver, there’s a certain appeal in wandering the relaxed inland blocks of San Miguel, away from the piers, spotting Maya ruins and birds (the Maya called the island cuzamil – “land of the swallows”) in the dense forests and being the only person on the windswept eastern beaches. Midway across the island, San Gervasio is the only excavated Maya site on Cozumel. With several small temples connected by sacbeob, or long white roads, it was one of the many independent city-states that survived the fall of Chichén Itzá, flourishing between 1200 AD and 1650 AD. As part of a larger nature reserve the site is worth a visit for the numerous birds and butterflies you can spot early in the morning or late in the day. Another place to visit is Xcaret, a surprisingly pleasant theme park: it offers all the Yucatán’s attractions in one handy place, with a museum, a tropical aquarium, a “Maya village”, a beach, some small authentic ruins, pools and more than a kilometre of subterranean rivers down which you can swim, snorkel or float. On the other hand, neighbouring Xplor is dedicated to ziplines and other outdoor adventure. Cozumel port guide Search cruises visiting Cozumel

Day 4 Mar 8, 2027 Puerto Costa Maya 07:00 – 19:00 12.0 hrs ashore Puerto Costa Maya, where the Caribbean and Antilles MSC cruise ships dock, is out of sight north of Mahahual, but its influence is felt on cruise-ship days, when the village springs to life with souvenir stands and jet-ski rentals along the slick seafront promenade, an extremely miniature version of Playa del Carmen. The two towns in the area, Mahahual and the smaller Xcalak, were hit hard by Hurricane Dean in 2007. Mahahual was rebuilt, but Xcalak is still quite battered. On an MSC Caribbean and Antilles cruise you will typically stay around Mahahual, while divers and anglers head south to Xcalak. If you stop for only one ancient site in the Río Bec area, Kohunlich is your best excursion choice. The ruins, seldom visited by anyone other than enormous butterflies and wild parrots, are beautifully situated, peering out above the treetops. The buildings date from the late pre-Classic to the Classic periods (100–900 AD) and the majority are in the Río Bec architectural style. Foliage has reclaimed most of them, except for the Templo de los Mascarones, which is named after the five 2m-high stucco masks that decorate its facade. Disturbing enough now, these wide-eyed, open-mouthed images of the sun god, Kinich Ahau, once stared out from a background of smooth, bright-red-painted stucco. Also look for an elite residential area called the 27 Escalones, worth the detour to see the great views over the jungle canopy from the cliff edge on which it is built. Set in a drier area with sparse trees, these two neighbouring ruins are an interesting contrast to Kohunlich. Kinichná’s hulking pyramid, built in metre-high stones, layer upon layer by successive leaders, barely clears the trees, but you can look over the surrounding terrain (and spot a glimpse of the Dzibanché ancient Maya archaeological site), now broken into farmland. Puerto Costa Maya port guide Search cruises visiting Puerto Costa Maya

Puerto Costa Maya photo — Day 4 Mar 8, 2027 Puerto Costa Maya 07:00 – 19:00 12.0 hrs ashore Puerto Costa Maya, where the Caribbean and Antilles MSC cruise ships dock, is out of sight north of Mahahual, but its influence is felt on cruise-ship days, when the village springs to life with souvenir stands and jet-ski rentals along the slick seafront promenade, an extremely miniature version of Playa del Carmen. The two towns in the area, Mahahual and the smaller Xcalak, were hit hard by Hurricane Dean in 2007. Mahahual was rebuilt, but Xcalak is still quite battered. On an MSC Caribbean and Antilles cruise you will typically stay around Mahahual, while divers and anglers head south to Xcalak. If you stop for only one ancient site in the Río Bec area, Kohunlich is your best excursion choice. The ruins, seldom visited by anyone other than enormous butterflies and wild parrots, are beautifully situated, peering out above the treetops. The buildings date from the late pre-Classic to the Classic periods (100–900 AD) and the majority are in the Río Bec architectural style. Foliage has reclaimed most of them, except for the Templo de los Mascarones, which is named after the five 2m-high stucco masks that decorate its facade. Disturbing enough now, these wide-eyed, open-mouthed images of the sun god, Kinich Ahau, once stared out from a background of smooth, bright-red-painted stucco. Also look for an elite residential area called the 27 Escalones, worth the detour to see the great views over the jungle canopy from the cliff edge on which it is built. Set in a drier area with sparse trees, these two neighbouring ruins are an interesting contrast to Kohunlich. Kinichná’s hulking pyramid, built in metre-high stones, layer upon layer by successive leaders, barely clears the trees, but you can look over the surrounding terrain (and spot a glimpse of the Dzibanché ancient Maya archaeological site), now broken into farmland. Puerto Costa Maya port guide Search cruises visiting Puerto Costa Maya

Day 5 Mar 9, 2027 Harvest Caye 08:00 – 17:00 9.0 hrs ashore Featuring an enchanting range of environments such as tropical rainforests, marshes and coral reefs, Harvest Caye offers both relaxation and adventure amid lush landscapes. This 75-acre paradise invites you to explore its incredibly biodiverse surroundings, witnessing exotic wildlife or perhaps discovering the world’s second largest coral reef. Gain insight into the region’s Mayan and Garifuna roots, discover traditional arts and traditions at the local artisans’ village or simply soak up the abundant Belizean sunshine and relax. Harvest Caye port guide Search cruises visiting Harvest Caye

Harvest Caye photo — Day 5 Mar 9, 2027 Harvest Caye 08:00 – 17:00 9.0 hrs ashore Featuring an enchanting range of environments such as tropical rainforests, marshes and coral reefs, Harvest Caye offers both relaxation and adventure amid lush landscapes. This 75-acre paradise invites you to explore its incredibly biodiverse surroundings, witnessing exotic wildlife or perhaps discovering the world’s second largest coral reef. Gain insight into the region’s Mayan and Garifuna roots, discover traditional arts and traditions at the local artisans’ village or simply soak up the abundant Belizean sunshine and relax. Harvest Caye port guide Search cruises visiting Harvest Caye

Day 6 Mar 10, 2027 Santo Tomas De Castilla, Guatemala 07:00 – 18:00 11.0 hrs ashore One of two major Guatemalan ports on the Gulf coast, Santo Tomás de Castilla is a few kilometers south of Puerto Barrios on Santo Tomás Bay. It is Guatemala’s largest and most efficient port on the Caribbean Ocean. It was formerly known as Matías de Galvez, and now handles 77% of the country's exports and half the imports, as well as 20% of El Salvador's imports and 10% of its exports. It is a wonderful place to get an authentic taste of local Guatemalan culture.

Day 7 Mar 11, 2027 Roatan, Bay Islands 07:00 – 17:00 10.0 hrs ashore Setting foot on Isla de Roatán, off the coast of Honduras, is like entering an incredible work of art where the mountainous lush green junglescape meets the glorious blue sea, and deep coves hide pirates of the past. Roatán, after all, was at one point home to more than 5,000 pirates. Largely untouched, Roatán is known for its barrier reef, fishing and diving cultures. The island offers easy access to beautiful beaches and its coral reef, a sanctuary for snorkelers and divers exploring the bounty of its marine life. You’ll arrive on an MSC Caribbean and Antilles cruise into Coxen Hole, the capital of the island, aptly named after the pirate who anchored his ship here at the end of the 17th century. Head off the beaten track to explore the picturesque fishing villages of Punta Gorda, with its Garifuna people, descendants of island Caribs and African slaves, and Oak Ridge, a village on stilts only accessible by boat. Here in an exclusive Martha Stewart excursion curated for MSC, you’ll learn about the local fishing culture, taste local delicacies and explore the island’s waterways and mangroves. For something more adventurous, book one of several MSC excursions that will have you darting across suspension bridges, zip lining through jungle canopy and mingling with monkeys, toucans, parrots and many other birds that inhabit the local forests. Seeking more vibes? Head to popular West Bay for excellent cocktails, beautiful beaches, shopping and entertainment that livens the atmosphere in the rhythm of Caribbean music. Roatan, Bay Islands port guide Search cruises visiting Roatan, Bay Islands

Day 9 Mar 13, 2027 Puerto Limon 07:00 – 17:00 10.0 hrs ashore From mountainous cloud forests and volcanoes to tropical rainforests, Costa Rica in Central America is renowned for its biodiversity and environmental conservation. When you arrive on an MSC Caribbean and Antilles cruisein Puerto Limón, you’ll discover the biggest city on Costa Rica’s Caribbean coast as well as the most important port in the country. From the port, Limón is a perfect starting point for adventurous explorers on one of many MSC excursions that will let you be one with nature in what is called Costa Rica’s Amazon. Enjoy a boat adventure down the jungle-fringed Tortuguero Canal, spotting orchids, water lilies, crocodiles, spider monkeys, manatees and otters along the way. Wave to the locals busy on the banks or in dugout canoes on the water as you pass. On another MSC excursion, spend half a day meeting some of Costa Rica’s cutest creatures: sloths. The Sloth Sanctuary of Costa Rica, founded as a not-for-profit rescue centre in 1997, lets you mingle with some of the coolest dudes in the jungle with their languid movements and permanently smiling faces. Your time at the sanctuary also includes a canoe ride along the freshwater of the Estrella River, a habitat for 180 bird species, monkeys, turtles and scores of butterflies. Soar through the tree canopy on an aerial tramway at Veragua Rainforest Research & Adventure Park, walk to a beautiful waterfall and rub shoulders with myriad butterflies, including the incredible blue morpho. Then, on this thrilling MSC excursion, zip line across 11 observation plat-forms and 9 traverses on an amazing course which has you gliding over the rainforest canopy, spotting monkeys, sloths and toucans in the trees. Or explore Afro-Caribbean culture, passing through Limón’s oldest neighbourhoods with houses on stilts and banana and cassava plantations, before watching local dancers perform to Caribbean rhythms and share Costa Rican traditions. Puerto Limon port guide Search cruises visiting Puerto Limon

Day 10 Mar 14, 2027 Panama City Arrives 20:00 You probably can’t think of Panama City without conjuring images of the Panama Canal. But nearly 400 years before the Panama Canal opened its locks, Panama City was making its mark. From the vestiges of the original settlement to the modern skyscrapers, experience the history and culture of one of the Pacific Coast’s oldest continuously inhabited European settlements. After exploring the bustling local markets in search of fresh fish or artisan handicrafts, admire the restored Spanish Colonial architecture in Casco Viejo. Or you can head to the Miraflores Locks and watch one of the modern world’s most heroic feats of engineering in action. Panama City port guide Search cruises visiting Panama City

Panama City photo — Day 10 Mar 14, 2027 Panama City Arrives 20:00 You probably can’t think of Panama City without conjuring images of the Panama Canal. But nearly 400 years before the Panama Canal opened its locks, Panama City was making its mark. From the vestiges of the original settlement to the modern skyscrapers, experience the history and culture of one of the Pacific Coast’s oldest continuously inhabited European settlements. After exploring the bustling local markets in search of fresh fish or artisan handicrafts, admire the restored Spanish Colonial architecture in Casco Viejo. Or you can head to the Miraflores Locks and watch one of the modern world’s most heroic feats of engineering in action. Panama City port guide Search cruises visiting Panama City

Pricing

Lowest fare we've tracked over the observed 93-day span: $2,700 · range $2,700–$3,099

Lower than 100% of peers This longer-duration sailing's from-price per night is lower than 100% of comparable sailings.

same cruise line, destination, duration, and departure window · from-price per night · as of Jun 25, 2026

Current prices

Per person · 2 guests · incl. taxes & fees

Inside

from $2,790

$279 / night

Fare rows

Inside Stateroom 1

Cabin grade

Available

from $2,790

$279 / night

per person · incl. taxes

Inside Stateroom 1

Cabin grade

Available

from $3,099

$309 / night

per person · incl. taxes

Inside Stateroom 1

Cabin grade

Available

from $3,099

$309 / night

per person · incl. taxes

Oceanview

from $3,510

$351 / night

Fare rows

Deluxe Ocean View

Cabin grade

Available

from $3,510

$351 / night

per person · incl. taxes

Deluxe Ocean View

Cabin grade

Available

from $3,899

$389 / night

per person · incl. taxes

Deluxe Ocean View

Cabin grade

Available

from $3,899

$389 / night

per person · incl. taxes

Balcony

from $4,275

$427 / night

Fare rows

Veranda Stateroom 4

Cabin grade

Available

from $4,275

$427 / night

per person · incl. taxes

Veranda Stateroom 3

Cabin grade

Available

from $4,410

$441 / night

per person · incl. taxes

Veranda Stateroom 2

Cabin grade

Available

from $4,455

$445 / night

per person · incl. taxes

Veranda Stateroom 1

Cabin grade

Available

from $4,500

$450 / night

per person · incl. taxes

Concierge Level 4

Cabin grade

Available

from $4,545

$454 / night

per person · incl. taxes

Concierge Level 3

Cabin grade

Available

from $4,590

$459 / night

per person · incl. taxes

Concierge Level 2

Cabin grade

Available

from $4,725

$472 / night

per person · incl. taxes

Veranda Stateroom 4

Cabin grade

Available

from $4,749

$474 / night

per person · incl. taxes

Veranda Stateroom 4

Cabin grade

Available

from $4,749

$474 / night

per person · incl. taxes

Concierge Level 1

Cabin grade

Available

from $4,770

$477 / night

per person · incl. taxes

Veranda Stateroom 3

Cabin grade

Available

from $4,899

$489 / night

per person · incl. taxes

Veranda Stateroom 3

Cabin grade

Available

from $4,899

$489 / night

per person · incl. taxes

Veranda Stateroom 2

Cabin grade

Available

from $4,949

$494 / night

per person · incl. taxes

Veranda Stateroom 2

Cabin grade

Available

from $4,949

$494 / night

per person · incl. taxes

Veranda Stateroom 1

Cabin grade

Available

from $4,999

$499 / night

per person · incl. taxes

Veranda Stateroom 1

Cabin grade

Available

from $4,999

$499 / night

per person · incl. taxes

Concierge Level 4

Cabin grade

Available

from $5,049

$504 / night

per person · incl. taxes

Concierge Level 4

Cabin grade

Available

from $5,049

$504 / night

per person · incl. taxes

Concierge Level 3

Cabin grade

Available

from $5,099

$509 / night

per person · incl. taxes

Concierge Level 3

Cabin grade

Available

from $5,099

$509 / night

per person · incl. taxes

Concierge Level 2

Cabin grade

Available

from $5,249

$524 / night

per person · incl. taxes

Concierge Level 2

Cabin grade

Available

from $5,249

$524 / night

per person · incl. taxes

Concierge Level 1

Cabin grade

Available

from $5,299

$529 / night

per person · incl. taxes

Concierge Level 1

Cabin grade

Available

from $5,299

$529 / night

per person · incl. taxes

Suite

from $6,030

$603 / night

Fare rows

Penthouse Suite 2

Cabin grade

Available

from $6,030

$603 / night

per person · incl. taxes

Penthouse Suite 1

Cabin grade

Available

from $6,165

$616 / night

per person · incl. taxes

Penthouse Suite 2

Cabin grade

Available

from $6,699

$669 / night

per person · incl. taxes

Penthouse Suite 2

Cabin grade

Available

from $6,699

$669 / night

per person · incl. taxes

Penthouse Suite 1

Cabin grade

Available

from $6,849

$684 / night

per person · incl. taxes

Penthouse Suite 1

Cabin grade

Available

from $6,849

$684 / night

per person · incl. taxes

Oceania Suite

Cabin grade

Available

from $10,149

$1,014 / night

per person · incl. taxes

Oceania Suite

Cabin grade

Available

from $10,149

$1,014 / night

per person · incl. taxes

Vista Suite

Cabin grade

Available

from $11,399

$1,139 / night

per person · incl. taxes

Vista Suite

Cabin grade

Available

from $11,399

$1,139 / night

per person · incl. taxes

Owner's Suite

Cabin grade

Available

from $13,949

$1,394 / night

per person · incl. taxes

Owner's Suite

Cabin grade

Available

from $13,949

$1,394 / night

per person · incl. taxes

Prices verified Jun 24, 2026

Prices come from third-party data feeds via Oceania Cruises and may differ from the cruise line's current fare. Confirm the final price before booking. How our pricing works

Show all 17 cabin grades

Name	Supplier code	Type
Concierge Level 1	A1	Balcony
Concierge Level 2	A2	Balcony
Concierge Level 3	A3	Balcony
Concierge Level 4	A4	Balcony
Veranda Stateroom 1	B1	Balcony
Veranda Stateroom 2	B2	Balcony
Veranda Stateroom 3	B3	Balcony
Veranda Stateroom 4	B4	Balcony
Inside Stateroom 1	F	Inside
Inside Stateroom 2	G	Inside
Deluxe Ocean View	C	Oceanview
Oceania Suite	OC	Suite
Owner's Suite	OS	Suite
Penthouse Suite 1	PH1	Suite
Penthouse Suite 2	PH2	Suite
Penthouse Suite 3	PH3	Suite
Vista Suite	VS	Suite