Miami to Panama City

14 nights Jan 12, 2027

The Miami to Panama City is a 14-night Worldwide cruise aboard Seven Seas Splendor, operated by Regent Seven Seas Cruises. Departing Miami, Florida on January 12, 2027, the voyage visits 10 ports. Fares start from $14,099 per person.

Itinerary

Day 1 Jan 12, 2027 Miami, Florida Departs 18:00 Miami is called the gateway to the Americas, and it’s indeed a very glamourous global city to explore at the start or end of an MSC Caribbean and Antilles cruise. Home to many cultures, the city of Miami sizzles with flavours from the Americas, beginning with Cuba and the Little Havana neighbourhood - one of the most historically significant places, while Wynwood is famous for its wall art and Puerto Rican history. Across Biscayne Bay lies the city of Miami Beach, home to the world-famous South Beach. An MSC-arranged guided private tour opens up a world of possibilities for you: enjoy the beach, take in the city’s Art Deco architecture and enjoy a drink on legendary Ocean Drive, where you can people watch, and perhaps spot a celebrity. If time permits, take a stroll on artsy Lincoln Road packed with street side cafes and shops. Facing the MSC Cruises port in downtown Miami is Bayside Marketplace - a lively commercial centre that is a staging area for boat tours of Miami. Seeing the city from the water, with its impressive skyline and waterfront mansions, is an experience in itself. The downtown area also boasts the dazzling Performing Arts Centre, the Museum of Science, the Pérez Art Museum Miami (known as the PAMM), scenic Bayfront Park and the arena where the 3-time NBA champion Miami Heat basketball team plays. Miami is renowned for its shopping. Hop on a tour to see the major city sights followed by retail therapy at one of Miami's largest and newest shopping malls: Dolphin Mall. With more than 240 retail outlets, you’re bound to need a bit of room in your luggage for your purchases. Luckily, there are several luggage stores at the mall to fill that need. Head west past the city into untamed wilderness on an MSC excursion into the Everglades. At this national park where water is the central feature, unlike any other in North America, nature enthusiasts can hop on an airboat tour through the swampland and waterways to spot alligators and a variety of birds. Go to Miami, Florida Cruises visiting Miami, Florida

Miami, Florida photo — Day 1 Jan 12, 2027 Miami, Florida Departs 18:00 Miami is called the gateway to the Americas, and it’s indeed a very glamourous global city to explore at the start or end of an MSC Caribbean and Antilles cruise. Home to many cultures, the city of Miami sizzles with flavours from the Americas, beginning with Cuba and the Little Havana neighbourhood - one of the most historically significant places, while Wynwood is famous for its wall art and Puerto Rican history. Across Biscayne Bay lies the city of Miami Beach, home to the world-famous South Beach. An MSC-arranged guided private tour opens up a world of possibilities for you: enjoy the beach, take in the city’s Art Deco architecture and enjoy a drink on legendary Ocean Drive, where you can people watch, and perhaps spot a celebrity. If time permits, take a stroll on artsy Lincoln Road packed with street side cafes and shops. Facing the MSC Cruises port in downtown Miami is Bayside Marketplace - a lively commercial centre that is a staging area for boat tours of Miami. Seeing the city from the water, with its impressive skyline and waterfront mansions, is an experience in itself. The downtown area also boasts the dazzling Performing Arts Centre, the Museum of Science, the Pérez Art Museum Miami (known as the PAMM), scenic Bayfront Park and the arena where the 3-time NBA champion Miami Heat basketball team plays. Miami is renowned for its shopping. Hop on a tour to see the major city sights followed by retail therapy at one of Miami's largest and newest shopping malls: Dolphin Mall. With more than 240 retail outlets, you’re bound to need a bit of room in your luggage for your purchases. Luckily, there are several luggage stores at the mall to fill that need. Head west past the city into untamed wilderness on an MSC excursion into the Everglades. At this national park where water is the central feature, unlike any other in North America, nature enthusiasts can hop on an airboat tour through the swampland and waterways to spot alligators and a variety of birds. Go to Miami, Florida Cruises visiting Miami, Florida

Day 3 Jan 14, 2027 Cozumel 07:00 – 17:00 10.0 hrs ashore A forty-kilometre-long island directly off the coast from Playa del Carmen, Isla Cozumel is a renowned cruise-ship call: nearly every day, up to ten cruise ships dock at one of the island’s three dedicated piers, all just south of the only town, San Miguel. A holiday to Mexico with MSC Cruises will present you with restaurants, souvenir shops and jewellery stores, all along the malecón(Av Rafael Melgar) in downtown San Miguel. If you fancy a museum, the attractive Museo de la Isla de Cozumel has small displays of the flora, fauna and marine life of the island, as well as a good collection of Maya artefacts and old photos. If you’re not a diver, there’s a certain appeal in wandering the relaxed inland blocks of San Miguel, away from the piers, spotting Maya ruins and birds (the Maya called the island cuzamil – “land of the swallows”) in the dense forests and being the only person on the windswept eastern beaches. Midway across the island, San Gervasio is the only excavated Maya site on Cozumel. With several small temples connected by sacbeob, or long white roads, it was one of the many independent city-states that survived the fall of Chichén Itzá, flourishing between 1200 AD and 1650 AD. As part of a larger nature reserve the site is worth a visit for the numerous birds and butterflies you can spot early in the morning or late in the day. Another place to visit is Xcaret, a surprisingly pleasant theme park: it offers all the Yucatán’s attractions in one handy place, with a museum, a tropical aquarium, a “Maya village”, a beach, some small authentic ruins, pools and more than a kilometre of subterranean rivers down which you can swim, snorkel or float. On the other hand, neighbouring Xplor is dedicated to ziplines and other outdoor adventure. Go to Cozumel Cruises visiting Cozumel

Cozumel photo — Day 3 Jan 14, 2027 Cozumel 07:00 – 17:00 10.0 hrs ashore A forty-kilometre-long island directly off the coast from Playa del Carmen, Isla Cozumel is a renowned cruise-ship call: nearly every day, up to ten cruise ships dock at one of the island’s three dedicated piers, all just south of the only town, San Miguel. A holiday to Mexico with MSC Cruises will present you with restaurants, souvenir shops and jewellery stores, all along the malecón(Av Rafael Melgar) in downtown San Miguel. If you fancy a museum, the attractive Museo de la Isla de Cozumel has small displays of the flora, fauna and marine life of the island, as well as a good collection of Maya artefacts and old photos. If you’re not a diver, there’s a certain appeal in wandering the relaxed inland blocks of San Miguel, away from the piers, spotting Maya ruins and birds (the Maya called the island cuzamil – “land of the swallows”) in the dense forests and being the only person on the windswept eastern beaches. Midway across the island, San Gervasio is the only excavated Maya site on Cozumel. With several small temples connected by sacbeob, or long white roads, it was one of the many independent city-states that survived the fall of Chichén Itzá, flourishing between 1200 AD and 1650 AD. As part of a larger nature reserve the site is worth a visit for the numerous birds and butterflies you can spot early in the morning or late in the day. Another place to visit is Xcaret, a surprisingly pleasant theme park: it offers all the Yucatán’s attractions in one handy place, with a museum, a tropical aquarium, a “Maya village”, a beach, some small authentic ruins, pools and more than a kilometre of subterranean rivers down which you can swim, snorkel or float. On the other hand, neighbouring Xplor is dedicated to ziplines and other outdoor adventure. Go to Cozumel Cruises visiting Cozumel

Day 4 Jan 15, 2027 Puerto Costa Maya 07:00 – 17:00 10.0 hrs ashore Puerto Costa Maya, where the Caribbean and Antilles MSC cruise ships dock, is out of sight north of Mahahual, but its influence is felt on cruise-ship days, when the village springs to life with souvenir stands and jet-ski rentals along the slick seafront promenade, an extremely miniature version of Playa del Carmen. The two towns in the area, Mahahual and the smaller Xcalak, were hit hard by Hurricane Dean in 2007. Mahahual was rebuilt, but Xcalak is still quite battered. On an MSC Caribbean and Antilles cruise you will typically stay around Mahahual, while divers and anglers head south to Xcalak. If you stop for only one ancient site in the Río Bec area, Kohunlich is your best excursion choice. The ruins, seldom visited by anyone other than enormous butterflies and wild parrots, are beautifully situated, peering out above the treetops. The buildings date from the late pre-Classic to the Classic periods (100–900 AD) and the majority are in the Río Bec architectural style. Foliage has reclaimed most of them, except for the Templo de los Mascarones, which is named after the five 2m-high stucco masks that decorate its facade. Disturbing enough now, these wide-eyed, open-mouthed images of the sun god, Kinich Ahau, once stared out from a background of smooth, bright-red-painted stucco. Also look for an elite residential area called the 27 Escalones, worth the detour to see the great views over the jungle canopy from the cliff edge on which it is built. Set in a drier area with sparse trees, these two neighbouring ruins are an interesting contrast to Kohunlich. Kinichná’s hulking pyramid, built in metre-high stones, layer upon layer by successive leaders, barely clears the trees, but you can look over the surrounding terrain (and spot a glimpse of the Dzibanché ancient Maya archaeological site), now broken into farmland. Go to Puerto Costa Maya Cruises visiting Puerto Costa Maya

Puerto Costa Maya photo — Day 4 Jan 15, 2027 Puerto Costa Maya 07:00 – 17:00 10.0 hrs ashore Puerto Costa Maya, where the Caribbean and Antilles MSC cruise ships dock, is out of sight north of Mahahual, but its influence is felt on cruise-ship days, when the village springs to life with souvenir stands and jet-ski rentals along the slick seafront promenade, an extremely miniature version of Playa del Carmen. The two towns in the area, Mahahual and the smaller Xcalak, were hit hard by Hurricane Dean in 2007. Mahahual was rebuilt, but Xcalak is still quite battered. On an MSC Caribbean and Antilles cruise you will typically stay around Mahahual, while divers and anglers head south to Xcalak. If you stop for only one ancient site in the Río Bec area, Kohunlich is your best excursion choice. The ruins, seldom visited by anyone other than enormous butterflies and wild parrots, are beautifully situated, peering out above the treetops. The buildings date from the late pre-Classic to the Classic periods (100–900 AD) and the majority are in the Río Bec architectural style. Foliage has reclaimed most of them, except for the Templo de los Mascarones, which is named after the five 2m-high stucco masks that decorate its facade. Disturbing enough now, these wide-eyed, open-mouthed images of the sun god, Kinich Ahau, once stared out from a background of smooth, bright-red-painted stucco. Also look for an elite residential area called the 27 Escalones, worth the detour to see the great views over the jungle canopy from the cliff edge on which it is built. Set in a drier area with sparse trees, these two neighbouring ruins are an interesting contrast to Kohunlich. Kinichná’s hulking pyramid, built in metre-high stones, layer upon layer by successive leaders, barely clears the trees, but you can look over the surrounding terrain (and spot a glimpse of the Dzibanché ancient Maya archaeological site), now broken into farmland. Go to Puerto Costa Maya Cruises visiting Puerto Costa Maya

Day 5 Jan 16, 2027 Harvest Caye 07:00 – 17:00 10.0 hrs ashore Featuring an enchanting range of environments such as tropical rainforests, marshes and coral reefs, Harvest Caye offers both relaxation and adventure amid lush landscapes. This 75-acre paradise invites you to explore its incredibly biodiverse surroundings, witnessing exotic wildlife or perhaps discovering the world’s second largest coral reef. Gain insight into the region’s Mayan and Garifuna roots, discover traditional arts and traditions at the local artisans’ village or simply soak up the abundant Belizean sunshine and relax. Go to Harvest Caye Cruises visiting Harvest Caye

Harvest Caye photo — Day 5 Jan 16, 2027 Harvest Caye 07:00 – 17:00 10.0 hrs ashore Featuring an enchanting range of environments such as tropical rainforests, marshes and coral reefs, Harvest Caye offers both relaxation and adventure amid lush landscapes. This 75-acre paradise invites you to explore its incredibly biodiverse surroundings, witnessing exotic wildlife or perhaps discovering the world’s second largest coral reef. Gain insight into the region’s Mayan and Garifuna roots, discover traditional arts and traditions at the local artisans’ village or simply soak up the abundant Belizean sunshine and relax. Go to Harvest Caye Cruises visiting Harvest Caye

Day 6 Jan 17, 2027 Roatan, Bay Islands 07:00 – 17:00 10.0 hrs ashore Setting foot on Isla de Roatán, off the coast of Honduras, is like entering an incredible work of art where the mountainous lush green junglescape meets the glorious blue sea, and deep coves hide pirates of the past. Roatán, after all, was at one point home to more than 5,000 pirates. Largely untouched, Roatán is known for its barrier reef, fishing and diving cultures. The island offers easy access to beautiful beaches and its coral reef, a sanctuary for snorkelers and divers exploring the bounty of its marine life. You’ll arrive on an MSC Caribbean and Antilles cruise into Coxen Hole, the capital of the island, aptly named after the pirate who anchored his ship here at the end of the 17th century. Head off the beaten track to explore the picturesque fishing villages of Punta Gorda, with its Garifuna people, descendants of island Caribs and African slaves, and Oak Ridge, a village on stilts only accessible by boat. Here in an exclusive Martha Stewart excursion curated for MSC, you’ll learn about the local fishing culture, taste local delicacies and explore the island’s waterways and mangroves. For something more adventurous, book one of several MSC excursions that will have you darting across suspension bridges, zip lining through jungle canopy and mingling with monkeys, toucans, parrots and many other birds that inhabit the local forests. Seeking more vibes? Head to popular West Bay for excellent cocktails, beautiful beaches, shopping and entertainment that livens the atmosphere in the rhythm of Caribbean music. Go to Roatan, Bay Islands Cruises visiting Roatan, Bay Islands

Day 8 Jan 19, 2027 George Town, Cayman Islands 07:00 – 16:00 9.0 hrs ashore Christopher Columbus called the Cayman Islands, with their tranquil blue waters, "Las Tortugas" for its abundance of turtles. Located between Cuba and Jamaica, the Cayman Islands are comprised of three Caribbean islands: Grand Cayman, Little Cayman and Cayman Brac. Beautiful landscapes, bountiful wildlife and colourful streets embody this British Overseas Territory, with George Town, its capital, located on Grand Cayman, the largest and most populous island. When you arrive in George Town on an MSC Caribbean and Antilles cruise, you’ll discover that wildlife conservation is at the core of Grand Cayman’s offerings. For the chance of a lifetime to swim, feed and interact with stingrays, book an MSC excursion to Stingray City, where you’ll get an up-close experience with Cayman’s most graceful marine creatures. On yet another MSC excursion to the Cayman Turtle Centre, encounter the green turtles that return each and every year to lay their eggs on one of the beaches, visit the turtle hatchery, snorkel alongside yearlings in the Turtle Lagoon and meet the island’s endangered blue iguanas. For a special experience, ride horses bareback into the Caribbean Sea at Barker’s National Park on an exclusive Martha Stewart excursion curated just for MSC Cruises, followed by lunch at Vivo café, a spot beloved for its mostly vegan cuisine, with organic ingredients sourced straight from local farms. To learn about Cayman’s past and culture, explore Cayman Heritage House and visit the sumptuous Government House, the governor's residence built in 1964 located in front of Seven Mile Beach, one of the most prestigious beaches of Grand Cayman, in the heart of West Bay. Shopaholics will also delight in this destination. The Cayman Islands are entirely duty free. You just have to choose what catches your fancy among the myriad of watches, liqueurs, jewellery and porcelain on offer. Go to George Town, Cayman Islands Cruises visiting George Town, Cayman Islands

Day 9 Jan 20, 2027 Ocho Rios 09:00 – 17:00 8.0 hrs ashore While the name Ocho Rios means eight rivers in Spanish, a truer reflection of its name (considering the city has four rivers) may stem from its earlier Spanish name of Las Chorreras, referring to its waterfalls. In either case, it’s precisely its existing rivers, beautiful waterfalls and crystalline sea that promise to awe visitors to Jamaica who have a passion for the lush outdoors. For an unforgettable experience on an MSC Caribbean and Antilles cruise, try one of the many outdoor MSC excursions offered on the city’s rivers, such as kayaking, bamboo rafting and tubing, or try climbing one of its famous waterfalls. A must-see attraction is Dunn’s River Falls, where a guide will lead you up along an almost 600-foot stretch of naturally terraced river bed as part of a human chain. Once up on top, enjoy a breath-taking panorama worthy of photos, and explore a craft market and numerous shops. Or ascend Konoko Falls to admire the tropical gardens with sinuously shaped flowers and a mini zoo of exotic birds and reptiles, before embarking on a gastronomic farm-to-table experience and traditional Jamaican buffet lunch in the hills of Claremont at the organic Murphy Hill Farm, on an exclusive Martha Stewart excursion for MSC. Music lovers can’t help but pay tribute to reggae legend Bob Marley. Journey to Bob Marley’s Nine Mile, a nearby mountaintop village, to see the birthplace and final resting place of the star. The MSC excursion includes a visit to a small Ethiopian-style church housing the marble mausoleum in which Marley’s remains have been entombed along with his guitar. And James Bond fans can take heart in the fact that it was here in Jamaica in the 1950s and 1960s that author Ian Fleming created 007 and wrote every one of the 14 books featuring the stealth secret agent from his villa at nearby Oracabessa Bay. Scenes for the 1962 movie “Dr. No” and the 1973 film “Live and Let Die” were filmed in and around Ocho Rios. Go to Ocho Rios Cruises visiting Ocho Rios

Ocho Rios photo — Day 9 Jan 20, 2027 Ocho Rios 09:00 – 17:00 8.0 hrs ashore While the name Ocho Rios means eight rivers in Spanish, a truer reflection of its name (considering the city has four rivers) may stem from its earlier Spanish name of Las Chorreras, referring to its waterfalls. In either case, it’s precisely its existing rivers, beautiful waterfalls and crystalline sea that promise to awe visitors to Jamaica who have a passion for the lush outdoors. For an unforgettable experience on an MSC Caribbean and Antilles cruise, try one of the many outdoor MSC excursions offered on the city’s rivers, such as kayaking, bamboo rafting and tubing, or try climbing one of its famous waterfalls. A must-see attraction is Dunn’s River Falls, where a guide will lead you up along an almost 600-foot stretch of naturally terraced river bed as part of a human chain. Once up on top, enjoy a breath-taking panorama worthy of photos, and explore a craft market and numerous shops. Or ascend Konoko Falls to admire the tropical gardens with sinuously shaped flowers and a mini zoo of exotic birds and reptiles, before embarking on a gastronomic farm-to-table experience and traditional Jamaican buffet lunch in the hills of Claremont at the organic Murphy Hill Farm, on an exclusive Martha Stewart excursion for MSC. Music lovers can’t help but pay tribute to reggae legend Bob Marley. Journey to Bob Marley’s Nine Mile, a nearby mountaintop village, to see the birthplace and final resting place of the star. The MSC excursion includes a visit to a small Ethiopian-style church housing the marble mausoleum in which Marley’s remains have been entombed along with his guitar. And James Bond fans can take heart in the fact that it was here in Jamaica in the 1950s and 1960s that author Ian Fleming created 007 and wrote every one of the 14 books featuring the stealth secret agent from his villa at nearby Oracabessa Bay. Scenes for the 1962 movie “Dr. No” and the 1973 film “Live and Let Die” were filmed in and around Ocho Rios. Go to Ocho Rios Cruises visiting Ocho Rios

Day 11 Jan 22, 2027 Puerto Limon 10:00 – 19:00 9.0 hrs ashore From mountainous cloud forests and volcanoes to tropical rainforests, Costa Rica in Central America is renowned for its biodiversity and environmental conservation. When you arrive on an MSC Caribbean and Antilles cruisein Puerto Limón, you’ll discover the biggest city on Costa Rica’s Caribbean coast as well as the most important port in the country. From the port, Limón is a perfect starting point for adventurous explorers on one of many MSC excursions that will let you be one with nature in what is called Costa Rica’s Amazon. Enjoy a boat adventure down the jungle-fringed Tortuguero Canal, spotting orchids, water lilies, crocodiles, spider monkeys, manatees and otters along the way. Wave to the locals busy on the banks or in dugout canoes on the water as you pass. On another MSC excursion, spend half a day meeting some of Costa Rica’s cutest creatures: sloths. The Sloth Sanctuary of Costa Rica, founded as a not-for-profit rescue centre in 1997, lets you mingle with some of the coolest dudes in the jungle with their languid movements and permanently smiling faces. Your time at the sanctuary also includes a canoe ride along the freshwater of the Estrella River, a habitat for 180 bird species, monkeys, turtles and scores of butterflies. Soar through the tree canopy on an aerial tramway at Veragua Rainforest Research & Adventure Park, walk to a beautiful waterfall and rub shoulders with myriad butterflies, including the incredible blue morpho. Then, on this thrilling MSC excursion, zip line across 11 observation plat-forms and 9 traverses on an amazing course which has you gliding over the rainforest canopy, spotting monkeys, sloths and toucans in the trees. Or explore Afro-Caribbean culture, passing through Limón’s oldest neighbourhoods with houses on stilts and banana and cassava plantations, before watching local dancers perform to Caribbean rhythms and share Costa Rican traditions. Go to Puerto Limon Cruises visiting Puerto Limon

Day 13 Jan 24, 2027 Cartagena, Colombia 07:00 – 14:00 7.0 hrs ashore Cobbled streets, balconies overflowing with blooming bougainvillea and pastel-coloured buildings lining elegant plazas make Cartagena in Colombia one of the Caribbean's most photogenic cities, and a memorable stop on an MSC Caribbean and Antilles cruise. Founded in 1533, this Spanish colonial city, a UNESCO World Heritage Site, is steeped in history. Its location made it a popular target for plunderers and English pirates, and arguably features the most impressive collection of forts in the Caribbean. Today the city is eager to share its treasures with modern visitors. Magnificent colonial structures such as the 16th-century Santa Catalina Cathedral, with its striking stuccoes and dome tower, and the three-arch clock gate, the Torre del Reloj, are just two of the many landmarks of this enchanting city dotted with many squares and sidewalk cafés. A wonderful photo stop on our Cartagena City MSC excursion is the San Felipe de Barajas fortress, a marvel of colonial Spanish military engineering. Its construction began in 1536. Slaves la-boured for more than 120 years to erect this fortress - built on high ground with dominating ap-proaches to the city by land and sea to fend off pirates - and its network of tunnels. On yet another MSC excursion, enrich your palate as you learn about the rich aromas and flavours of Colombian coffee. Introduced by the Jesuits in 1723, coffee quickly became a key crop in Colombia, which is now one of the top producers of Arabica coffee in the world. Colombia is also the world’s top producer of emeralds. If jewellery and gems fascinate you, learn all about these green precious stones and make your own emerald-studded jewellery in sterling silver during a hands-on MSC excursion that guides you step-by-step. And you don’t need to go far to explore nature. An MSC excursion takes you by canoe through mangrove tunnels to Ciénaga de la Virgen, where you can witness a diversity of birds from king-fishers and white herons to pelicans and pink-feathered roseate spoonbills. Go to Cartagena, Colombia Cruises visiting Cartagena, Colombia

Cartagena, Colombia photo — Day 13 Jan 24, 2027 Cartagena, Colombia 07:00 – 14:00 7.0 hrs ashore Cobbled streets, balconies overflowing with blooming bougainvillea and pastel-coloured buildings lining elegant plazas make Cartagena in Colombia one of the Caribbean's most photogenic cities, and a memorable stop on an MSC Caribbean and Antilles cruise. Founded in 1533, this Spanish colonial city, a UNESCO World Heritage Site, is steeped in history. Its location made it a popular target for plunderers and English pirates, and arguably features the most impressive collection of forts in the Caribbean. Today the city is eager to share its treasures with modern visitors. Magnificent colonial structures such as the 16th-century Santa Catalina Cathedral, with its striking stuccoes and dome tower, and the three-arch clock gate, the Torre del Reloj, are just two of the many landmarks of this enchanting city dotted with many squares and sidewalk cafés. A wonderful photo stop on our Cartagena City MSC excursion is the San Felipe de Barajas fortress, a marvel of colonial Spanish military engineering. Its construction began in 1536. Slaves la-boured for more than 120 years to erect this fortress - built on high ground with dominating ap-proaches to the city by land and sea to fend off pirates - and its network of tunnels. On yet another MSC excursion, enrich your palate as you learn about the rich aromas and flavours of Colombian coffee. Introduced by the Jesuits in 1723, coffee quickly became a key crop in Colombia, which is now one of the top producers of Arabica coffee in the world. Colombia is also the world’s top producer of emeralds. If jewellery and gems fascinate you, learn all about these green precious stones and make your own emerald-studded jewellery in sterling silver during a hands-on MSC excursion that guides you step-by-step. And you don’t need to go far to explore nature. An MSC excursion takes you by canoe through mangrove tunnels to Ciénaga de la Virgen, where you can witness a diversity of birds from king-fishers and white herons to pelicans and pink-feathered roseate spoonbills. Go to Cartagena, Colombia Cruises visiting Cartagena, Colombia

Day 14 Jan 25, 2027 Panama City Arrives 20:00 You probably can’t think of Panama City without conjuring images of the Panama Canal. But nearly 400 years before the Panama Canal opened its locks, Panama City was making its mark. From the vestiges of the original settlement to the modern skyscrapers, experience the history and culture of one of the Pacific Coast’s oldest continuously inhabited European settlements. After exploring the bustling local markets in search of fresh fish or artisan handicrafts, admire the restored Spanish Colonial architecture in Casco Viejo. Or you can head to the Miraflores Locks and watch one of the modern world’s most heroic feats of engineering in action. Go to Panama City Cruises visiting Panama City

Panama City photo — Day 14 Jan 25, 2027 Panama City Arrives 20:00 You probably can’t think of Panama City without conjuring images of the Panama Canal. But nearly 400 years before the Panama Canal opened its locks, Panama City was making its mark. From the vestiges of the original settlement to the modern skyscrapers, experience the history and culture of one of the Pacific Coast’s oldest continuously inhabited European settlements. After exploring the bustling local markets in search of fresh fish or artisan handicrafts, admire the restored Spanish Colonial architecture in Casco Viejo. Or you can head to the Miraflores Locks and watch one of the modern world’s most heroic feats of engineering in action. Go to Panama City Cruises visiting Panama City

Pricing

Lowest fare we've tracked over the observed 89-day span: $14,099 · range $14,099–$14,099

Current prices

Per person · 2 guests · incl. taxes & fees

Inside

Not available

Oceanview

Not available

Balcony

Not available

Suite

from $14,099

$1,007 / night

Fare rows

Veranda Suite

Cabin grade

Available

from $14,099

$1,007 / night

per person · incl. taxes

Deluxe Veranda Suite

Cabin grade

Available

from $14,299

$1,021 / night

per person · incl. taxes

Deluxe Veranda Suite

Cabin grade

Available

from $14,499

$1,035 / night

per person · incl. taxes

Serenity Suite

Cabin grade

Available

from $14,799

$1,057 / night

per person · incl. taxes

Serenity Suite

Cabin grade

Available

from $14,999

$1,071 / night

per person · incl. taxes

Concierge Suite

Cabin grade

Available

from $15,309

$1,093 / night

per person · incl. taxes

Concierge Suite

Cabin grade

Available

from $15,709

$1,122 / night

per person · incl. taxes

Veranda Suite

Cabin grade

Available

from $17,299

$1,235 / night

per person · incl. taxes

Veranda Suite

Cabin grade

Available

from $17,299

$1,235 / night

per person · incl. taxes

Deluxe Veranda Suite

Cabin grade

Available

from $17,499

$1,249 / night

per person · incl. taxes

Deluxe Veranda Suite

Cabin grade

Available

from $17,499

$1,249 / night

per person · incl. taxes

Deluxe Veranda Suite

Cabin grade

Available

from $17,699

$1,264 / night

per person · incl. taxes

Deluxe Veranda Suite

Cabin grade

Available

from $17,699

$1,264 / night

per person · incl. taxes

Serenity Suite

Cabin grade

Available

from $17,999

$1,285 / night

per person · incl. taxes

Serenity Suite

Cabin grade

Available

from $18,199

$1,299 / night

per person · incl. taxes

Concierge Suite

Cabin grade

Available

from $18,699

$1,335 / night

per person · incl. taxes

Concierge Suite

Cabin grade

Available

from $19,099

$1,364 / night

per person · incl. taxes

Penthouse Suite

Cabin grade

Available

from $20,409

$1,457 / night

per person · incl. taxes

Penthouse Suite

Cabin grade

Available

from $20,709

$1,479 / night

per person · incl. taxes

Penthouse Suite

Cabin grade

Available

from $21,509

$1,536 / night

per person · incl. taxes

Penthouse Suite

Cabin grade

Available

from $23,799

$1,699 / night

per person · incl. taxes

Penthouse Suite

Cabin grade

Available

from $24,099

$1,721 / night

per person · incl. taxes

Seven Seas Suite

Cabin grade

Available

from $24,259

$1,732 / night

per person · incl. taxes

Penthouse Suite

Cabin grade

Available

from $24,899

$1,778 / night

per person · incl. taxes

Seven Seas Suite

Cabin grade

Available

from $27,649

$1,974 / night

per person · incl. taxes

Splendor Suite

Cabin grade

Available

from $28,159

$2,011 / night

per person · incl. taxes

Splendor Suite

Cabin grade

Available

from $31,549

$2,253 / night

per person · incl. taxes

Grand Suite

Cabin grade

Available

from $32,609

$2,329 / night

per person · incl. taxes

Grand Suite

Cabin grade

Available

from $35,999

$2,571 / night

per person · incl. taxes

Prices verified Jun 21, 2026

Prices come from third-party data feeds via Regent Seven Seas Cruises and may differ from the cruise line's current fare. Confirm the final price before booking. How our pricing works

All cabin grades (15) Detailed cabin specs available at booking.

Name	Supplier code	Type
Penthouse Suite	A	Suite
Penthouse Suite	B	Suite
Penthouse Suite	C	Suite
Concierge Suite	D	Suite
Concierge Suite	E	Suite
Serenity Suite	F1	Suite
Serenity Suite	F2	Suite
Deluxe Veranda Suite	G1	Suite
Deluxe Veranda Suite	G2	Suite
Grand Suite	GS	Suite
Veranda Suite	H	Suite
Regent Suite	RS	Suite
Signature Suite	SG	Suite
Splendor Suite	SP	Suite
Seven Seas Suite	SS	Suite

Ship

Your ship Seven Seas Splendor 6★ **55,498** GT **746** guests Built **2020** To perfect luxury, Seven Seas Splendor elevates every detail, combining exquisite style and comfort with exemplary service, superb cuisine and all-balcony suites. Get to know this newest ship in the Regent Seven Seas Cruises fleet. Go to Seven Seas Splendor Cruises on Seven Seas Splendor

Fly-cruise options

Airport	Price pp	Included
ABQ	$25,249.00	Extra
ALB	$25,469.00	Extra
ATL	$25,189.00	Extra
AUS	$25,329.00	Extra
BDL	$25,469.00	Extra
BHM	$25,319.00	Extra
BNA	$25,319.00	Extra
BOI	$25,249.00	Extra
BOS	$25,269.00	Extra
BUF	$25,469.00	Extra
BWI	$25,169.00	Extra
CHS	$25,219.00	Extra
CID	$25,329.00	Extra
CLE	$25,319.00	Extra
CLT	$25,249.00	Extra
CMH	$25,319.00	Extra
CVG	$25,319.00	Extra
DCA	$25,169.00	Extra
DEN	$25,449.00	Extra
DFW	$25,329.00	Extra
DSM	$25,329.00	Extra
DTW	$25,199.00	Extra
ELP	$25,249.00	Extra
EWR	$25,219.00	Extra
FAR	$25,329.00	Extra
FAT	$25,369.00	Extra
FLL	$25,259.00	Extra
GRR	$25,319.00	Extra
GSO	$25,369.00	Extra
GSP	$25,219.00	Extra
GTF	$25,249.00	Extra
HNL	$25,369.00	Extra
HSV	$25,319.00	Extra
IAD	$25,169.00	Extra
IAH	$25,559.00	Extra
ICT	$25,329.00	Extra
IND	$25,319.00	Extra
JAN	$25,319.00	Extra
JAX	$25,249.00	Extra
JFK	$25,219.00	Extra
LAS	$25,249.00	Extra
LAX	$25,249.00	Extra
LBB	$25,329.00	Extra
LGA	$25,219.00	Extra
LIT	$25,329.00	Extra
MCI	$25,329.00	Extra
MCO	$25,319.00	Extra
MDW	$25,149.00	Extra
MEM	$25,319.00	Extra
MIA	$24,779.00	Extra
MKE	$25,329.00	Extra
MOB	$25,319.00	Extra
MSN	$25,329.00	Extra
MSP	$25,349.00	Extra
MSY	$25,329.00	Extra
OKC	$25,329.00	Extra
OMA	$25,329.00	Extra
ORD	$25,149.00	Extra
ORF	$25,219.00	Extra
PBI	$25,259.00	Extra
PDX	$25,369.00	Extra
PHL	$25,289.00	Extra
PHX	$25,249.00	Extra
PIT	$25,319.00	Extra
PSP	$25,369.00	Extra
PVD	$25,469.00	Extra
PWM	$25,469.00	Extra
RDU	$25,219.00	Extra
RIC	$25,219.00	Extra
RNO	$25,249.00	Extra
ROC	$25,469.00	Extra
RSW	$25,249.00	Extra
SAN	$25,449.00	Extra
SAT	$25,329.00	Extra
SAV	$25,219.00	Extra
SBA	$25,369.00	Extra
SDF	$25,319.00	Extra
SEA	$25,629.00	Extra
SFO	$25,599.00	Extra
SHV	$25,329.00	Extra
SJU	$17,548.00	Extra
SLC	$25,249.00	Extra
SMF	$25,369.00	Extra
SNA	$25,249.00	Extra
STL	$25,329.00	Extra
SYR	$25,469.00	Extra
TPA	$25,209.00	Extra
TUL	$25,329.00	Extra
TUS	$25,249.00	Extra
TYS	$25,319.00	Extra
YEG	$25,249.00	Extra
YOW	$25,469.00	Extra
YUL	$25,229.00	Extra
YVR	$25,429.00	Extra
YYC	$25,249.00	Extra
YYZ	$25,159.00	Extra

Miami to Panama City

Itinerary

Pricing

Current prices

Inside

Oceanview

Balcony

Suite

Price history

Ship

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Fly-cruise options