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21-night Western Mediterranean cruise: Naples to Santos, Brazil on MSC Virtuosa

The 21 nights South America from Naples (Pompeii) is a 21-night Western Mediterranean cruise aboard MSC Virtuosa, operated by MSC Cruises. Departing Naples on November 13, 2027 and arriving in Sao Paulo on December 4, 2027, the voyage visits 11 ports including Livorno, Marseille, France, Barcelona. Fares start from $1,850 per person.

Length
21 nights
Departs
Nov 13, 2027
Returns
Dec 4, 2027
Ports of call
11
Days at sea
11

Voyage code VI20271113NAPSSZ

Naples

21 nights · Western Mediterranean

from $1,850 pp

via CruiseDirect

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Why this route stands out

A closer look at the journey

Naples

Rising behind the wide curve of its bay with brooding Mount Vesuvius and the deep blue sea as a backdrop, Naples, Italy enjoys a magnificent natural setting. It is the third-largest city in Italy after Rome and Milan, and arguably the most colorful and seductive of them all: Splendor and squalor live side by side in 21st-century Naples, and the mix is intoxicating. Cruise to Naples, home to world-class museums and attractions. Naples has something for everyone - superb restaurants, eclectic shopping, a thriving contemporary art scene and an edgy and vibrant street life. But once you’ve had enough of the pounding traffic and jostling crowds while sightseeing in Naples, there are endless opportunities for exploration further afield. The celebrated Roman ruins of Pompeii and Herculaneum, both victims of Vesuvius’ devastating 79 C.E. eruption, lie just south of the city. Explore Naples' history or take a short ride over to the island of Capri on a Naples shore excursion. The delightful town of Sorrento and the magnificent scenery of the Amalfi Coast are also within easy reach, and the dolce vita glamour of Capri—not to mention the healing thermal waters of Ischia—are a short hydrofoil hop from the mainland. Naples cruises offer a perfect mix of cultural and natural attractions.

Livorno

There are few more elegant places to salute the sunset than Terrazza Mascagni, Livorno’s refined chessboard piazza. A historic port, and a beachy gateway to Tuscany, Livorno welcomes you ashore to explore this enchanted Italian region's sun-soaked beauty, rich flavours and world-renowned fine art. Stay in Livorno to explore 'Piccolo Venezia', or ‘Little Venice’ - a quarter of the town that's laced with canals, little marble bridges and plenty of tempting eateries. View less With its bustling market, fortresses and iconic waterfront, there’s plenty to keep you busy here, but most will be tempted to venture inland to explore more of Tuscany’s many charms and artistic wonders. Test your nose, as you breathe in the subtleties of Tuscany’s vineyard-draped scenery, and visit wineries showcasing the best of the renowned flavours of the Bolgheri wine-growing area. Or head out to Prato, where you’ll find tightly-woven textile history. Pisa’s showpiece tower is within reach, as is Florence’s city of immense and imaginative renaissance beauty. Admire the delicate carving of Michelangelo's masterpiece, the David statue, and note the provocative stance as he casts a dismissive glance towards Rome. Stand before the city’s majestic black and white cathedral - the Cathedral of Santa Maria del Fiore - with its colossal brick dome. The view down over Florence's river and grand dome from Piazzale Michelangelo, meanwhile, is one of Italy's finest. However you choose to spend your time in Tuscany, you’ll discover an artistic region, filled with beauty designed to appeal to every sense.

Marseille, France

Marseille is the second largest city in France after Paris. It is also one of the oldest continuously inhabited cities in the Mediterranean. Cave paintings in the nearby Calanques are estimated to be 30,000 years old, and remains of brick habitations date from 6,000 BCE. The more recent history begins with a Hellenic port in about 600 BCE, some remains of which are on view at the city’s History Museum. It has been one of the world’s major seaports almost from its founding, and served as the main European terminus of the French colonial empire in Africa and the Far East. It is located in the Provence-Alpes-Cote d’Azur region and is the capital of the Bouches-du-Rhone department. On an island in the expansive bay of Marseille stands the prison of Chateau d’If made famous by the Alexandre Dumas novel “The Count of Monte Cristo.” The Vieux-Port with its atmospheric buildings and wharves is the area where visitors can search for the perfect example of the local specialty bouillabaisse, a rich fish stew containing at least three, and often more varieties of local fishes. Marseille’s newly renovated port at the venerable Joliette Docks is situated very close to the striking Cathédrale de la Major and the fascinating collections at the Museum of African, Oceanic and American Indian Arts.

Price tracking

Today’s fare, in context

Price history

All
Fare details

Fare details

Per person · taxes & fees included
Current fares
Verified 2 days ago
Inside
$1,850
Balcony
$2,750
Suite
$8,440
Tracked range
161 days
Price history by cabin type
CabinCurrentLowestHighest
Inside $1,851 $1,851 on Aug 7 $1,881 on Jul 29
Balcony $2,751 $2,751 on Aug 12 $2,781 on Aug 7
Suite $8,441 $5,023 on Apr 22 $10,551 on Aug 21
Cabin grades
23 total
Balcony AureaBalcony · BA
Balcony BellaBalcony · BB
Deluxe Balcony With Partial View FANTASTICABalcony · BP
Deluxe Balcony FANTASTICABalcony · BR1
Deluxe Balcony FANTASTICABalcony · BR2
Deluxe Balcony FANTASTICABalcony · BR3
Studio Balcony FANTASTICABalcony · BS
Interior BellaInside · IB
Deluxe Interior FANTASTICAInside · IR1
Deluxe Interior FANTASTICAInside · IR2
Studio Interior FANTASTICAInside · IS
Ocean View BellaOceanview · OB
Premium Ocean View FANTASTICAOceanview · OL2
Junior Ocean View FANTASTICAOceanview · OM2
Junior Ocean View with obstructed view FANTASTICAOceanview · OO
Deluxe Ocean View FANTASTICAOceanview · OR1
Premium Suite AureaSuite · SL1
Premium Suite Aurea with Terrace and WhirlpoolSuite · SLJ
Grand Suite Aurea with Terrace and WhirlpoolSuite · SXJ
MSC Yacht Club Deluxe SuiteSuite · YC1
MSC Yacht Club Royal Suite with Whirlpool BathSuite · YC3
Yacht Club Interior SuiteSuite · YIN
MSC Yacht Club Duplex Suite with JacuzziSuite · YJD

○ = last seen (sold out or delisted). · Verified 2 days ago.

Lowest fares with no residency, age, or service requirement — verify eligibility at booking. How our pricing works

Current prices

Per person · 2 guests · incl. taxes & fees

Inside

from $1,850

$88 / night

Fare rows

Deluxe Interior FANTASTICA

Cabin grade

Available

from $1,850

$88 / night

per person · incl. taxes & fees

Deluxe Interior FANTASTICA

Cabin grade

Available

from $1,850

$88 / night

per person · incl. taxes & fees

Deluxe Interior FANTASTICA

Cabin grade

Available

from $1,880

$89 / night

per person · incl. taxes & fees

Deluxe Interior FANTASTICA

Cabin grade

Available

from $1,880

$89 / night

per person · incl. taxes & fees

Deluxe Interior FANTASTICA

Cabin grade

Available

from $2,984

$142 / night

per person · incl. taxes & fees

Deluxe Interior FANTASTICA

Cabin grade

Available

from $3,014

$143 / night

per person · incl. taxes & fees

Deluxe Interior FANTASTICA

Cabin grade

Available

from $3,567

$169 / night

per person · incl. taxes & fees

Deluxe Interior FANTASTICA

Cabin grade

Available

from $3,627

$172 / night

per person · incl. taxes & fees

Oceanview

Not available

Balcony

from $2,750

$130 / night

Fare rows

Deluxe Balcony FANTASTICA

Cabin grade

Available

from $2,750

$130 / night

per person · incl. taxes & fees

Deluxe Balcony FANTASTICA

Cabin grade

Available

from $2,750

$130 / night

per person · incl. taxes & fees

Deluxe Balcony FANTASTICA

Cabin grade

Available

from $2,780

$132 / night

per person · incl. taxes & fees

Deluxe Balcony FANTASTICA

Cabin grade

Available

from $2,780

$132 / night

per person · incl. taxes & fees

Deluxe Balcony FANTASTICA

Cabin grade

Available

from $3,884

$184 / night

per person · incl. taxes & fees

Deluxe Balcony FANTASTICA

Cabin grade

Available

from $3,914

$186 / night

per person · incl. taxes & fees

Deluxe Balcony FANTASTICA

Cabin grade

Available

from $5,367

$255 / night

per person · incl. taxes & fees

Deluxe Balcony FANTASTICA

Cabin grade

Available

from $5,427

$258 / night

per person · incl. taxes & fees

Suite

from $8,440

$401 / night

Fare rows

MSC Yacht Club Deluxe Suite

Cabin grade

Available

from $8,440

$401 / night

per person · incl. taxes & fees

MSC Yacht Club Deluxe Suite

Cabin grade

Available

from $8,440

$401 / night

per person · incl. taxes & fees

MSC Yacht Club Deluxe Suite

Cabin grade

Available

from $8,440

$401 / night

per person · incl. taxes & fees

MSC Yacht Club Duplex Suite with Jacuzzi

Cabin grade

Available

from $10,550

$502 / night

per person · incl. taxes & fees

MSC Yacht Club Duplex Suite with Jacuzzi

Cabin grade

Available

from $10,550

$502 / night

per person · incl. taxes & fees

MSC Yacht Club Duplex Suite with Jacuzzi

Cabin grade

Available

from $10,550

$502 / night

per person · incl. taxes & fees

MSC Yacht Club Deluxe Suite

Cabin grade

Available

from $16,747

$797 / night

per person · incl. taxes & fees

MSC Yacht Club Duplex Suite with Jacuzzi

Cabin grade

Available

from $20,967

$998 / night

per person · incl. taxes & fees

Prices verified Aug 30, 2026

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The journey

21 nights, in order

Naples

Day 1 Nov 13, 2027

Naples

Rising behind the wide curve of its bay with brooding Mount Vesuvius and the deep blue sea as a backdrop, Naples, Italy enjoys a magnificent natural setting.

Explore Naples

Day by day

The full itinerary

22 scheduled calls
MSC Virtuosa

Your ship

MSC Virtuosa

MSC Virtuosa’s namesake comes from the word virtuoso, meaning someone highly skilled in any field of activity, and so MSC Virtuosa was named to pay homage to the skill and expertise of the MSC Cruises architects and shipyard partners at Les Chantiers de l’Atlantique who designed and built this innovative class of ships. This new cruise ship is one of the two largest in MSC Cruises’ fleet, along with her sister ship MSC Grandiosa, boasting an impressive array of guest features all coming together in perfect harmony to deliver the ultimate cruise holiday experience.

5★ 181,541 GT 6,334 Passengers Built 2019
MSC Virtuosa ship guide Search cruises on MSC Virtuosa

Deck plans

Deck plan for Deck 6

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from $1,850 pp

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