16 nights South America from Santos (Sao Paulo)

The 16 nights South America from Santos (Sao Paulo) is a 16-night Brazil cruise aboard MSC Musica, operated by MSC Cruises. Departing Sao Paulo on April 1, 2027, the voyage visits 7 ports. Fares start from $1,023 per person.

Length: 16 nights
Departs: Apr 1, 2027
Returns: Apr 17, 2027
Ports of call: 7
Days at sea: 10

from $1,023

$63 / night per person, incl. taxes & fees

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Itinerary

Day 1 Apr 1, 2027 Sao Paulo Departs 18:00 São Paulo, Brazil’s vibrant financial center, is among the world's most populous cities, with numerous cultural institutions and a rich architectural tradition. Its iconic buildings range from its neo-Gothic cathedral and the 1929 Martinelli skyscraper to modernist architect Oscar Niemeyer’s curvy Edifício Copan. The colonial-style Pátio do Colégio church marks where Jesuit priests founded the city in 1554. Sao Paulo port guide Search cruises visiting Sao Paulo

Sao Paulo photo — Day 1 Apr 1, 2027 Sao Paulo Departs 18:00 São Paulo, Brazil’s vibrant financial center, is among the world's most populous cities, with numerous cultural institutions and a rich architectural tradition. Its iconic buildings range from its neo-Gothic cathedral and the 1929 Martinelli skyscraper to modernist architect Oscar Niemeyer’s curvy Edifício Copan. The colonial-style Pátio do Colégio church marks where Jesuit priests founded the city in 1554. Sao Paulo port guide Search cruises visiting Sao Paulo

Day 2 Apr 2, 2027 Rio de Janeiro 07:00 – 18:00 11.0 hrs ashore As you’ll be able to appreciate when you cruise the Atlantic Ocean with MSC Cruises, in its position on the southern shore of the magnificent Guanabara Bay, Rio de Janeiro has, without a shadow of a doubt, one of the most stunning settings in the world. Extending for 20km along an alluvial strip, between an azure sea and forest-clad mountains, the city’s streets and buildings have been moulded around the foothills of the mountain range that provides its backdrop, while out in the bay there are many rocky islands fringed with white sand. The aerial views over Rio are breathtaking, and even the concrete skyscrapers that dominate the city’s skyline add to the attraction. As the former capital of Brazil and now its second-largest city, Rio has a remarkable architectural heritage, some of the country’s best museums and galleries, superb restaurants and a vibrant nightlife – in addition to its legendary beaches. A shore excursion on your MSC South America cruise can be the opportunity to visit the Pão de Açúcar. The Sugar Loaf Mountain rises where Guanabara Bay meets the Atlantic Ocean. Its name may simply reflect a resemblance to the moulded loaves in which sugar was once commonly sold. Alternatively, it may be a corruption of the indigenous Tamoya word Pau-nh-Açuquá, meaning “high, pointed or isolated hill”. On the top of Corcoavado Mountain instead the Art Deco statue of Cristo Redentor (Christ the Redeemer), arms outstretched in welcome, stands 30m high and weighs over 1000 tonnes. It was supposed to be completed for Brazil’s centenary independence celebrations in 1922, but wasn’t actually finished until 1931. In clear weather, fear no anticlimax: climbing to the statue is a stunning experience, with the whole of Rio and Guanabara Bay laid out before you. Rio de Janeiro port guide Search cruises visiting Rio de Janeiro

Rio de Janeiro photo — Day 2 Apr 2, 2027 Rio de Janeiro 07:00 – 18:00 11.0 hrs ashore As you’ll be able to appreciate when you cruise the Atlantic Ocean with MSC Cruises, in its position on the southern shore of the magnificent Guanabara Bay, Rio de Janeiro has, without a shadow of a doubt, one of the most stunning settings in the world. Extending for 20km along an alluvial strip, between an azure sea and forest-clad mountains, the city’s streets and buildings have been moulded around the foothills of the mountain range that provides its backdrop, while out in the bay there are many rocky islands fringed with white sand. The aerial views over Rio are breathtaking, and even the concrete skyscrapers that dominate the city’s skyline add to the attraction. As the former capital of Brazil and now its second-largest city, Rio has a remarkable architectural heritage, some of the country’s best museums and galleries, superb restaurants and a vibrant nightlife – in addition to its legendary beaches. A shore excursion on your MSC South America cruise can be the opportunity to visit the Pão de Açúcar. The Sugar Loaf Mountain rises where Guanabara Bay meets the Atlantic Ocean. Its name may simply reflect a resemblance to the moulded loaves in which sugar was once commonly sold. Alternatively, it may be a corruption of the indigenous Tamoya word Pau-nh-Açuquá, meaning “high, pointed or isolated hill”. On the top of Corcoavado Mountain instead the Art Deco statue of Cristo Redentor (Christ the Redeemer), arms outstretched in welcome, stands 30m high and weighs over 1000 tonnes. It was supposed to be completed for Brazil’s centenary independence celebrations in 1922, but wasn’t actually finished until 1931. In clear weather, fear no anticlimax: climbing to the statue is a stunning experience, with the whole of Rio and Guanabara Bay laid out before you. Rio de Janeiro port guide Search cruises visiting Rio de Janeiro

Day 5 Apr 5, 2027 Maceio 07:00 – 16:00 9.0 hrs ashore On your South America cruise to Brazil, you’ll come across the big and burgeoning beach resort of Maceió, its striking beaches and clear, turquoise waters attracting cruisers from all over the world. It’s also smack in the middle of a far longer strip of some of the best beaches in the country, all easily accessible on day trips. When you arrive with your MSC cruise in Maceió, you’ll start off in the affluent and lively resort area that starts at Pajuçara, a few kilometres to the east of downtown, built along a spectacular beach. While the city centre itself, the commercial and administrative heart of the city just inland from a more polluted (and generally deserted) stretch of sand and the grubby port district, is somewhat down-at-heel it does have a smattering of belle époque buildings and enticing museums. However, what you’ll want to discover on your MSC South America cruise excursion is the amazing beaches. Sixteen kilometres south of Maceió, the coast road loops around Praia do Francês, which even by Alagoan standards is something special. An enormous expanse of white sand, surf and thick palm forest, it even boasts several pousadas or inns, and a burgeoning restaurant scene. Most folks end up at the northern end, a protected lagoon formed by a large reef offshore; surfers take in the pounding waves at the less busy and unsheltered end. Beach bars line the northern section, while Avenida Dos Corais and Rua da Algas run parallel to the sand and are lined with shops and restaurants. Given its proximity to Maceió, it’s no surprise Francês has effectively become a city beach – so expect a lively atmosphere. Maceio port guide Search cruises visiting Maceio

Maceio photo — Day 5 Apr 5, 2027 Maceio 07:00 – 16:00 9.0 hrs ashore On your South America cruise to Brazil, you’ll come across the big and burgeoning beach resort of Maceió, its striking beaches and clear, turquoise waters attracting cruisers from all over the world. It’s also smack in the middle of a far longer strip of some of the best beaches in the country, all easily accessible on day trips. When you arrive with your MSC cruise in Maceió, you’ll start off in the affluent and lively resort area that starts at Pajuçara, a few kilometres to the east of downtown, built along a spectacular beach. While the city centre itself, the commercial and administrative heart of the city just inland from a more polluted (and generally deserted) stretch of sand and the grubby port district, is somewhat down-at-heel it does have a smattering of belle époque buildings and enticing museums. However, what you’ll want to discover on your MSC South America cruise excursion is the amazing beaches. Sixteen kilometres south of Maceió, the coast road loops around Praia do Francês, which even by Alagoan standards is something special. An enormous expanse of white sand, surf and thick palm forest, it even boasts several pousadas or inns, and a burgeoning restaurant scene. Most folks end up at the northern end, a protected lagoon formed by a large reef offshore; surfers take in the pounding waves at the less busy and unsheltered end. Beach bars line the northern section, while Avenida Dos Corais and Rua da Algas run parallel to the sand and are lined with shops and restaurants. Given its proximity to Maceió, it’s no surprise Francês has effectively become a city beach – so expect a lively atmosphere. Maceio port guide Search cruises visiting Maceio

Day 12 Apr 12, 2027 Las Palmas,Gran Canaria 07:00 – 17:00 10.0 hrs ashore With its feel of mainland-Spain, spiced up with an eclectic mix of Asian and African cultures, Las Palmas is one of the Canary Island's most popular destinations, attracting sun-seekers who come to relax on its golden-sand beaches and soak up the gorgeous, year-round climate of Gran Canaria. Founded over 500 years ago, Las Palmas is the largest city in the Canary Islands, and has three gorgeous beaches, including Playa de las Canteras, regarded as one of the world's best beaches, to enjoy. Vegueta, the oldest quarter, is both atmospheric and fashionable, with extensive historical architecture plus a fine selection of boutiques and smart bars. At its centre stand the twin towers of Santa Ana Cathedral; started in 1500 but still unfinished, the cathedral has a unique mix of Renaissance, Gothic and Neoclassical styles in its construction. In Plaza Santa Ana, bronze statues of dogs – the Romans named the islands after legendary canines – stand guard over the 17th-century Palacio Regental, the Town Hall and the Bishop's Palace. The sweet arc of Playa de las Canteras at the town’s other end offers the tantalising possibility of taking a dip between sightseeing and shopping. The bewildering maze of streets behind the beach hides many fine restaurants serving an array of wonderful Canarian cuisine. Las Palmas,Gran Canaria port guide Search cruises visiting Las Palmas,Gran Canaria

Las Palmas,Gran Canaria photo — Day 12 Apr 12, 2027 Las Palmas,Gran Canaria 07:00 – 17:00 10.0 hrs ashore With its feel of mainland-Spain, spiced up with an eclectic mix of Asian and African cultures, Las Palmas is one of the Canary Island's most popular destinations, attracting sun-seekers who come to relax on its golden-sand beaches and soak up the gorgeous, year-round climate of Gran Canaria. Founded over 500 years ago, Las Palmas is the largest city in the Canary Islands, and has three gorgeous beaches, including Playa de las Canteras, regarded as one of the world's best beaches, to enjoy. Vegueta, the oldest quarter, is both atmospheric and fashionable, with extensive historical architecture plus a fine selection of boutiques and smart bars. At its centre stand the twin towers of Santa Ana Cathedral; started in 1500 but still unfinished, the cathedral has a unique mix of Renaissance, Gothic and Neoclassical styles in its construction. In Plaza Santa Ana, bronze statues of dogs – the Romans named the islands after legendary canines – stand guard over the 17th-century Palacio Regental, the Town Hall and the Bishop's Palace. The sweet arc of Playa de las Canteras at the town’s other end offers the tantalising possibility of taking a dip between sightseeing and shopping. The bewildering maze of streets behind the beach hides many fine restaurants serving an array of wonderful Canarian cuisine. Las Palmas,Gran Canaria port guide Search cruises visiting Las Palmas,Gran Canaria

Day 15 Apr 15, 2027 Tarragona 09:00 – 18:00 9.0 hrs ashore Tarragona, port city of Spain, is located less than 100 km from Barcelona from the top of its walls, here you can admire one of the most important Gothic cathedrals in Catalonia and the immense amphitheatre, stage for gladiatorial combat in Roman times. During your Mediterranean cruise, you will visit the Port of Tarragona; a true gem, with Roman ruins that are the pride of its residents and historical traditions that are part of the local folklore. The Roman heritage is still part of the urban context in Tarragona. Here, you can watch the reenactments of the centurion parades and gladiatorial combat. During the stop in the port of Tarragona, proceed to the Praetorian Tower. On the first floor there is a model of the medieval town and its glory that was lost during a war that is still commemorated with solemn candles on the steps of the cathedral. If you have the time, watch the races of human pyramids that are organised in various districts of the city. Tarragona port guide Search cruises visiting Tarragona

Tarragona photo — Day 15 Apr 15, 2027 Tarragona 09:00 – 18:00 9.0 hrs ashore Tarragona, port city of Spain, is located less than 100 km from Barcelona from the top of its walls, here you can admire one of the most important Gothic cathedrals in Catalonia and the immense amphitheatre, stage for gladiatorial combat in Roman times. During your Mediterranean cruise, you will visit the Port of Tarragona; a true gem, with Roman ruins that are the pride of its residents and historical traditions that are part of the local folklore. The Roman heritage is still part of the urban context in Tarragona. Here, you can watch the reenactments of the centurion parades and gladiatorial combat. During the stop in the port of Tarragona, proceed to the Praetorian Tower. On the first floor there is a model of the medieval town and its glory that was lost during a war that is still commemorated with solemn candles on the steps of the cathedral. If you have the time, watch the races of human pyramids that are organised in various districts of the city. Tarragona port guide Search cruises visiting Tarragona

Day 16 Apr 16, 2027 Marseille, France 08:00 – 17:00 9.0 hrs ashore Marseille is the second largest city in France after Paris. It is also one of the oldest continuously inhabited cities in the Mediterranean. Cave paintings in the nearby Calanques are estimated to be 30,000 years old, and remains of brick habitations date from 6,000 BCE. The more recent history begins with a Hellenic port in about 600 BCE, some remains of which are on view at the city’s History Museum. It has been one of the world’s major seaports almost from its founding, and served as the main European terminus of the French colonial empire in Africa and the Far East. It is located in the Provence-Alpes-Cote d’Azur region and is the capital of the Bouches-du-Rhone department. On an island in the expansive bay of Marseille stands the prison of Chateau d’If made famous by the Alexandre Dumas novel “The Count of Monte Cristo.” The Vieux-Port with its atmospheric buildings and wharves is the area where visitors can search for the perfect example of the local specialty bouillabaisse, a rich fish stew containing at least three, and often more varieties of local fishes. Marseille’s newly renovated port at the venerable Joliette Docks is situated very close to the striking Cathédrale de la Major and the fascinating collections at the Museum of African, Oceanic and American Indian Arts. Marseille, France port guide Search cruises visiting Marseille, France

Marseille, France photo — Day 16 Apr 16, 2027 Marseille, France 08:00 – 17:00 9.0 hrs ashore Marseille is the second largest city in France after Paris. It is also one of the oldest continuously inhabited cities in the Mediterranean. Cave paintings in the nearby Calanques are estimated to be 30,000 years old, and remains of brick habitations date from 6,000 BCE. The more recent history begins with a Hellenic port in about 600 BCE, some remains of which are on view at the city’s History Museum. It has been one of the world’s major seaports almost from its founding, and served as the main European terminus of the French colonial empire in Africa and the Far East. It is located in the Provence-Alpes-Cote d’Azur region and is the capital of the Bouches-du-Rhone department. On an island in the expansive bay of Marseille stands the prison of Chateau d’If made famous by the Alexandre Dumas novel “The Count of Monte Cristo.” The Vieux-Port with its atmospheric buildings and wharves is the area where visitors can search for the perfect example of the local specialty bouillabaisse, a rich fish stew containing at least three, and often more varieties of local fishes. Marseille’s newly renovated port at the venerable Joliette Docks is situated very close to the striking Cathédrale de la Major and the fascinating collections at the Museum of African, Oceanic and American Indian Arts. Marseille, France port guide Search cruises visiting Marseille, France

Day 17 Apr 17, 2027 Genoa, Italy Arrives 08:00 Genoa is marvellously eclectic, vibrant and full of rough-edged style; it’s a great cruise excursion. Indeed “La Superba” (The Superb), as it was known at the height of its authority as a Mediterranean superpower, boasts more zest and intrigue than all the surrounding coastal resorts put together. During a holiday to Genoa you can explore its old town: a dense and fascinating warren of medieval alleyways home to large palazzi built in the sixteenth and seventeenth centuries by Genoa’s wealthy mercantile families and now transformed into museums and art galleries. You should seek out the Cattedrale di San Lorenzo, the Palazzo Ducale, and the Renaissance palaces of Via Garibaldi which contain the cream of Genoa’s art collections, as well as furniture and decor from the grandest days of the city’s past, when its ships sailed to all corners of the Mediterranean Sea. The Acquario di Genova is the city’s pride and joy, parked like a giant ocean liner on the waterfront, with seventy tanks housing sea creatures from all the world’s major habitats, including the world’s biggest reconstruction of a Caribbean coral reef. It’s a great aquarium by any standards, the second largest in Europe by capacity, and boasts a fashionably ecology-conscious slant and excellent background information in Italian and English. Just 35 km south of Genoa, there’s no denying the appeal of Portofino, tucked into a protected inlet surrounded by lush cypress- and olive-clad slopes. It’s an A-list resort that has been attracting high-flying bankers, celebs and their hangers-on for years, as evidenced by the flotillas of giant yachts usually anchored just outside. It’s a tiny place that is attractive yet somehow off-putting at the same time, with a quota of fancy shops, bars and restaurants for a place twice its size. Genoa, Italy port guide Search cruises visiting Genoa, Italy

Genoa, Italy photo — Day 17 Apr 17, 2027 Genoa, Italy Arrives 08:00 Genoa is marvellously eclectic, vibrant and full of rough-edged style; it’s a great cruise excursion. Indeed “La Superba” (The Superb), as it was known at the height of its authority as a Mediterranean superpower, boasts more zest and intrigue than all the surrounding coastal resorts put together. During a holiday to Genoa you can explore its old town: a dense and fascinating warren of medieval alleyways home to large palazzi built in the sixteenth and seventeenth centuries by Genoa’s wealthy mercantile families and now transformed into museums and art galleries. You should seek out the Cattedrale di San Lorenzo, the Palazzo Ducale, and the Renaissance palaces of Via Garibaldi which contain the cream of Genoa’s art collections, as well as furniture and decor from the grandest days of the city’s past, when its ships sailed to all corners of the Mediterranean Sea. The Acquario di Genova is the city’s pride and joy, parked like a giant ocean liner on the waterfront, with seventy tanks housing sea creatures from all the world’s major habitats, including the world’s biggest reconstruction of a Caribbean coral reef. It’s a great aquarium by any standards, the second largest in Europe by capacity, and boasts a fashionably ecology-conscious slant and excellent background information in Italian and English. Just 35 km south of Genoa, there’s no denying the appeal of Portofino, tucked into a protected inlet surrounded by lush cypress- and olive-clad slopes. It’s an A-list resort that has been attracting high-flying bankers, celebs and their hangers-on for years, as evidenced by the flotillas of giant yachts usually anchored just outside. It’s a tiny place that is attractive yet somehow off-putting at the same time, with a quota of fancy shops, bars and restaurants for a place twice its size. Genoa, Italy port guide Search cruises visiting Genoa, Italy

Pricing

Lowest fare we've tracked over the observed 79-day span: $913 · range $913–$1,023

Lower than 83% of peers This extended sailing's from-price per night is lower than 83% of comparable sailings.

same cruise line and duration · from-price per night · as of Jun 23, 2026 · Broader cohort: same cruise line and duration, compared by from-price per night.

Current prices

Per person · 2 guests · incl. taxes & fees

Inside

from $1,023

$63 / night

Fare rows

DELUXE INTERIOR FANTASTICA

Cabin grade

Available

from $1,023

$63 / night

per person · incl. taxes

DELUXE INTERIOR FANTASTICA

Cabin grade

Available

from $1,887

$117 / night

per person · incl. taxes

DELUXE INTERIOR FANTASTICA

Cabin grade

Available

from $1,932

$120 / night

per person · incl. taxes

Oceanview

from $1,153

$72 / night

Fare rows

OCEAN VIEW BELLA GUARANTEED

Cabin grade

Available

from $1,153

$72 / night

per person · incl. taxes

DELUXE OCEAN VIEW WITH OBSTRUCTED VIEW FANTASTICA

Cabin grade

Available

from $1,183

$73 / night

per person · incl. taxes

DELUXE OCEAN VIEW FANTASTICA

Cabin grade

Available

from $1,263

$78 / night

per person · incl. taxes

DELUXE OCEAN VIEW FANTASTICA

Cabin grade

Available

from $1,283

$80 / night

per person · incl. taxes

OCEAN VIEW BELLA GUARANTEED

Cabin grade

Available

from $2,017

$126 / night

per person · incl. taxes

DELUXE OCEAN VIEW WITH OBSTRUCTED VIEW FANTASTICA

Cabin grade

Available

from $2,047

$127 / night

per person · incl. taxes

DELUXE OCEAN VIEW FANTASTICA

Cabin grade

Available

from $2,127

$132 / night

per person · incl. taxes

DELUXE OCEAN VIEW FANTASTICA

Cabin grade

Available

from $2,147

$134 / night

per person · incl. taxes

OCEAN VIEW BELLA GUARANTEED

Cabin grade

Available

from $2,192

$137 / night

per person · incl. taxes

DELUXE OCEAN VIEW WITH OBSTRUCTED VIEW FANTASTICA

Cabin grade

Available

from $2,252

$140 / night

per person · incl. taxes

DELUXE OCEAN VIEW FANTASTICA

Cabin grade

Available

from $2,412

$150 / night

per person · incl. taxes

DELUXE OCEAN VIEW FANTASTICA

Cabin grade

Available

from $2,452

$153 / night

per person · incl. taxes

Balcony

from $1,413

$88 / night

Fare rows

BALCONY BELLA GUARANTEED

Cabin grade

Available

from $1,413

$88 / night

per person · incl. taxes

DELUXE BALCONY FANTASTICA

Cabin grade

Available

from $1,583

$98 / night

per person · incl. taxes

DELUXE BALCONY FANTASTICA

Cabin grade

Available

from $1,603

$100 / night

per person · incl. taxes

PREMIUM BALCONY FANTASTICA

Cabin grade

Available

from $1,663

$103 / night

per person · incl. taxes

PREMIUM BALCONY FANTASTICA

Cabin grade

Available

from $1,693

$105 / night

per person · incl. taxes

BALCONY AUREA

Cabin grade

Available

from $1,993

$124 / night

per person · incl. taxes

BALCONY BELLA GUARANTEED

Cabin grade

Available

from $2,277

$142 / night

per person · incl. taxes

DELUXE BALCONY FANTASTICA

Cabin grade

Available

from $2,447

$152 / night

per person · incl. taxes

DELUXE BALCONY FANTASTICA

Cabin grade

Available

from $2,467

$154 / night

per person · incl. taxes

PREMIUM BALCONY FANTASTICA

Cabin grade

Available

from $2,527

$157 / night

per person · incl. taxes

PREMIUM BALCONY FANTASTICA

Cabin grade

Available

from $2,557

$159 / night

per person · incl. taxes

BALCONY BELLA GUARANTEED

Cabin grade

Available

from $2,712

$169 / night

per person · incl. taxes

BALCONY AUREA

Cabin grade

Available

from $2,857

$178 / night

per person · incl. taxes

DELUXE BALCONY FANTASTICA

Cabin grade

Available

from $3,052

$190 / night

per person · incl. taxes

DELUXE BALCONY FANTASTICA

Cabin grade

Available

from $3,092

$193 / night

per person · incl. taxes

PREMIUM BALCONY FANTASTICA

Cabin grade

Available

from $3,212

$200 / night

per person · incl. taxes

PREMIUM BALCONY FANTASTICA

Cabin grade

Available

from $3,272

$204 / night

per person · incl. taxes

BALCONY AUREA

Cabin grade

Available

from $3,872

$242 / night

per person · incl. taxes

Suite

Not available

Prices verified Jun 23, 2026

Prices come from third-party data feeds via MSC Cruises and may differ from the cruise line's current fare. Confirm the final price before booking. How our pricing works

Show all 16 cabin grades

Name	Supplier code	Type
BALCONY AUREA	BA	Balcony
BALCONY BELLA GUARANTEED	BB	Balcony
PREMIUM BALCONY FANTASTICA	BL1	Balcony
PREMIUM BALCONY FANTASTICA	BL2	Balcony
DELUXE BALCONY WITH PARTIAL VIEW FANTASTICA	BP	Balcony
DELUXE BALCONY FANTASTICA	BR1	Balcony
DELUXE BALCONY FANTASTICA	BR2	Balcony
INTERIOR BELLA GUARANTEED	IB	Inside
DELUXE INTERIOR FANTASTICA	IR1	Inside
DELUXE INTERIOR FANTASTICA	IR2	Inside
Inside Cabin	SPL	Inside
OCEAN VIEW BELLA GUARANTEED	OB	Oceanview
DELUXE OCEAN VIEW WITH OBSTRUCTED VIEW FANTASTICA	OO	Oceanview
DELUXE OCEAN VIEW FANTASTICA	OR1	Oceanview
DELUXE OCEAN VIEW FANTASTICA	OR2	Oceanview
PREMIUM SUITE AUREA	SL1	Suite