12 nights Western Mediterranean from Genoa (Portofino)

The 12 nights Western Mediterranean from Genoa (Portofino) is a 12-night Mediterranean cruise aboard MSC Sinfonia, operated by MSC Cruises. Departing Genoa, Italy on April 6, 2027, the voyage visits 6 ports. Fares start from $1,332 per person.

Length: 12 nights
Departs: Apr 6, 2027
Returns: Apr 18, 2027
Ports of call: 6
Days at sea: 3

from $1,332

$111 / night per person, incl. taxes & fees

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Itinerary

Day 1 Apr 6, 2027 Genoa, Italy Departs 19:00 Genoa is marvellously eclectic, vibrant and full of rough-edged style; it’s a great cruise excursion. Indeed “La Superba” (The Superb), as it was known at the height of its authority as a Mediterranean superpower, boasts more zest and intrigue than all the surrounding coastal resorts put together. During a holiday to Genoa you can explore its old town: a dense and fascinating warren of medieval alleyways home to large palazzi built in the sixteenth and seventeenth centuries by Genoa’s wealthy mercantile families and now transformed into museums and art galleries. You should seek out the Cattedrale di San Lorenzo, the Palazzo Ducale, and the Renaissance palaces of Via Garibaldi which contain the cream of Genoa’s art collections, as well as furniture and decor from the grandest days of the city’s past, when its ships sailed to all corners of the Mediterranean Sea. The Acquario di Genova is the city’s pride and joy, parked like a giant ocean liner on the waterfront, with seventy tanks housing sea creatures from all the world’s major habitats, including the world’s biggest reconstruction of a Caribbean coral reef. It’s a great aquarium by any standards, the second largest in Europe by capacity, and boasts a fashionably ecology-conscious slant and excellent background information in Italian and English. Just 35 km south of Genoa, there’s no denying the appeal of Portofino, tucked into a protected inlet surrounded by lush cypress- and olive-clad slopes. It’s an A-list resort that has been attracting high-flying bankers, celebs and their hangers-on for years, as evidenced by the flotillas of giant yachts usually anchored just outside. It’s a tiny place that is attractive yet somehow off-putting at the same time, with a quota of fancy shops, bars and restaurants for a place twice its size. Genoa, Italy port guide Search cruises visiting Genoa, Italy

Genoa, Italy photo — Day 1 Apr 6, 2027 Genoa, Italy Departs 19:00 Genoa is marvellously eclectic, vibrant and full of rough-edged style; it’s a great cruise excursion. Indeed “La Superba” (The Superb), as it was known at the height of its authority as a Mediterranean superpower, boasts more zest and intrigue than all the surrounding coastal resorts put together. During a holiday to Genoa you can explore its old town: a dense and fascinating warren of medieval alleyways home to large palazzi built in the sixteenth and seventeenth centuries by Genoa’s wealthy mercantile families and now transformed into museums and art galleries. You should seek out the Cattedrale di San Lorenzo, the Palazzo Ducale, and the Renaissance palaces of Via Garibaldi which contain the cream of Genoa’s art collections, as well as furniture and decor from the grandest days of the city’s past, when its ships sailed to all corners of the Mediterranean Sea. The Acquario di Genova is the city’s pride and joy, parked like a giant ocean liner on the waterfront, with seventy tanks housing sea creatures from all the world’s major habitats, including the world’s biggest reconstruction of a Caribbean coral reef. It’s a great aquarium by any standards, the second largest in Europe by capacity, and boasts a fashionably ecology-conscious slant and excellent background information in Italian and English. Just 35 km south of Genoa, there’s no denying the appeal of Portofino, tucked into a protected inlet surrounded by lush cypress- and olive-clad slopes. It’s an A-list resort that has been attracting high-flying bankers, celebs and their hangers-on for years, as evidenced by the flotillas of giant yachts usually anchored just outside. It’s a tiny place that is attractive yet somehow off-putting at the same time, with a quota of fancy shops, bars and restaurants for a place twice its size. Genoa, Italy port guide Search cruises visiting Genoa, Italy

Day 2 Apr 7, 2027 Livorno 07:00 – 20:00 13.0 hrs ashore There are few more elegant places to salute the sunset than Terrazza Mascagni, Livorno’s refined chessboard piazza. A historic port, and a beachy gateway to Tuscany, Livorno welcomes you ashore to explore this enchanted Italian region's sun-soaked beauty, rich flavours and world-renowned fine art. Stay in Livorno to explore 'Piccolo Venezia', or ‘Little Venice’ - a quarter of the town that's laced with canals, little marble bridges and plenty of tempting eateries. View less With its bustling market, fortresses and iconic waterfront, there’s plenty to keep you busy here, but most will be tempted to venture inland to explore more of Tuscany’s many charms and artistic wonders. Test your nose, as you breathe in the subtleties of Tuscany’s vineyard-draped scenery, and visit wineries showcasing the best of the renowned flavours of the Bolgheri wine-growing area. Or head out to Prato, where you’ll find tightly-woven textile history. Pisa’s showpiece tower is within reach, as is Florence’s city of immense and imaginative renaissance beauty. Admire the delicate carving of Michelangelo's masterpiece, the David statue, and note the provocative stance as he casts a dismissive glance towards Rome. Stand before the city’s majestic black and white cathedral - the Cathedral of Santa Maria del Fiore - with its colossal brick dome. The view down over Florence's river and grand dome from Piazzale Michelangelo, meanwhile, is one of Italy's finest. However you choose to spend your time in Tuscany, you’ll discover an artistic region, filled with beauty designed to appeal to every sense. Livorno port guide Search cruises visiting Livorno

Livorno photo — Day 2 Apr 7, 2027 Livorno 07:00 – 20:00 13.0 hrs ashore There are few more elegant places to salute the sunset than Terrazza Mascagni, Livorno’s refined chessboard piazza. A historic port, and a beachy gateway to Tuscany, Livorno welcomes you ashore to explore this enchanted Italian region's sun-soaked beauty, rich flavours and world-renowned fine art. Stay in Livorno to explore 'Piccolo Venezia', or ‘Little Venice’ - a quarter of the town that's laced with canals, little marble bridges and plenty of tempting eateries. View less With its bustling market, fortresses and iconic waterfront, there’s plenty to keep you busy here, but most will be tempted to venture inland to explore more of Tuscany’s many charms and artistic wonders. Test your nose, as you breathe in the subtleties of Tuscany’s vineyard-draped scenery, and visit wineries showcasing the best of the renowned flavours of the Bolgheri wine-growing area. Or head out to Prato, where you’ll find tightly-woven textile history. Pisa’s showpiece tower is within reach, as is Florence’s city of immense and imaginative renaissance beauty. Admire the delicate carving of Michelangelo's masterpiece, the David statue, and note the provocative stance as he casts a dismissive glance towards Rome. Stand before the city’s majestic black and white cathedral - the Cathedral of Santa Maria del Fiore - with its colossal brick dome. The view down over Florence's river and grand dome from Piazzale Michelangelo, meanwhile, is one of Italy's finest. However you choose to spend your time in Tuscany, you’ll discover an artistic region, filled with beauty designed to appeal to every sense. Livorno port guide Search cruises visiting Livorno

Day 3 Apr 8, 2027 Civitavecchia, Rome 07:00 – 19:00 12.0 hrs ashore All roads lead to Rome, and with good reason - this city is one of the world’s most thrilling, offering unmatched history along every street. An evocative, inspiring and utterly artistic capital of unrivalled cultural impact, Rome is a city of back-to-back landmarks, which will take you on an exhilarating journey through the ages. This may be one of the world’s oldest cities, but it’s well and truly lived in. The ruins are punctuated with murmuring cafes, and the outdoor seating of restaurants sprawls out across piazzas, enticing you to sample tangles of creamy pasta and crispy pizzas. Rome’s incredible Roman Forum is littered with the ruins of its ancient administrations, which have stood firm for 2,000 years, since the times when the area was the centre of the Western world. Few sites are more simultaneously beautiful and haunting than that of the storied Colosseum, which looms deep into Rome’s rich blue sky. Take a tour to learn details of the grisly goings-on within. The best way to experience Rome is to wander its streets, gelato in hand. There is a lot to see here - whether it’s the domed spectacle of the Pantheon, or the elaborate flowing waters and artistry of the Trevi Fountain. Vatican City is an astonishing, colossal display of Catholic grandeur, while the Spanish Steps – crowned by the Trinità dei Monti church – offer a beautiful spot to gather and soak up the lively atmosphere of this humming city. With so much on the to-do list, you’ll relish the breaks you take, enjoying simple pleasures like a strong espresso, or fresh pasta with tomato sauce and ripped basil. Civitavecchia, Rome port guide Search cruises visiting Civitavecchia, Rome

Day 5 Apr 10, 2027 Valencia 07:00 – 21:00 14.0 hrs ashore Valencia is Spain's third largest city and capital of the region. It was originally founded by the Romans on the banks of the river Turia in 138 BC. In 711 AD the Moors arrived and converted the area into a rich agricultural and industrial center, establishing ceramics, paper, silk and leather industries. Muslim rule was briefly interrupted in 1094 by the legendary Castillian knight, El Cid. Valencia boomed in the 15th and 16th centuries, becoming one of the strongest Mediterranean trading centers. Valencia is a vibrant, friendly and chaotic city that boasts an outstanding fine arts museum and one of the most exciting nightlife scenes in Spain. The city center is about 3 miles inland from the coast. Plaza del Ayuntamiento marks the center of Valencia. Surrounded by flower stalls, it is also home to the town hall and the main post office. The cathedral was begun in the 13th century and finished in 1482. It has many architectural styles, including Gothic, Baroque and Romanesque. The octagonal bell-tower, called Miguelete, is one of the city's landmarks. The small cathedral museum boasts a tabernacle made from 550 pounds of gold, silver, platinum, emeralds and sapphires. It also purports to be the home of the Holy Grail, the cup used by Christ at the Last Supper. West of the cathedral is the oldest part of the city, known as El Carme. Situated across the river in the Jardines del Real is the Museo de Bellas Artes, the Fine Arts Museum. Works include those by El Greco, Goya and Velázquez. Valencia port guide Search cruises visiting Valencia

Valencia photo — Day 5 Apr 10, 2027 Valencia 07:00 – 21:00 14.0 hrs ashore Valencia is Spain's third largest city and capital of the region. It was originally founded by the Romans on the banks of the river Turia in 138 BC. In 711 AD the Moors arrived and converted the area into a rich agricultural and industrial center, establishing ceramics, paper, silk and leather industries. Muslim rule was briefly interrupted in 1094 by the legendary Castillian knight, El Cid. Valencia boomed in the 15th and 16th centuries, becoming one of the strongest Mediterranean trading centers. Valencia is a vibrant, friendly and chaotic city that boasts an outstanding fine arts museum and one of the most exciting nightlife scenes in Spain. The city center is about 3 miles inland from the coast. Plaza del Ayuntamiento marks the center of Valencia. Surrounded by flower stalls, it is also home to the town hall and the main post office. The cathedral was begun in the 13th century and finished in 1482. It has many architectural styles, including Gothic, Baroque and Romanesque. The octagonal bell-tower, called Miguelete, is one of the city's landmarks. The small cathedral museum boasts a tabernacle made from 550 pounds of gold, silver, platinum, emeralds and sapphires. It also purports to be the home of the Holy Grail, the cup used by Christ at the Last Supper. West of the cathedral is the oldest part of the city, known as El Carme. Situated across the river in the Jardines del Real is the Museo de Bellas Artes, the Fine Arts Museum. Works include those by El Greco, Goya and Velázquez. Valencia port guide Search cruises visiting Valencia

Day 6 Apr 11, 2027 Barcelona 09:00 – 18:00 9.0 hrs ashore On the northeast coast of Spain, overlooking the Mediterranean, Barcelona is a vibrant port city, packed with centuries of iconic art and architecture—Gaudí and Picasso both called it home—and lined with sunny white-sand beaches. Explore the Catalan capital's tourist attractions and historic neighborhoods, Modernisme and world-renowned art museums, galleries and local crafts shops—some of which are centuries old and stock traditional Catalan wares. After you see the sights, there are lively tapas bars around every corner where you can stop for a drink, a café amb llet (Catalan for espresso with steamed milk) or a snack, no matter the hour. Green spaces for picnics, long walks and respite from the hustle and bustle are scattered throughout Barcelona's attractions: There's Gaudí's mosaic-decorated park, a neoclassical maze at the Laberint d'Horta, as well as plenty of high places (mountains, monuments and edifices) where sightseeing visitors can take in the view. A short trip from Barcelona by car or train, luxury outlets, cava wineries, a mountaintop abbey and the sandy beaches of the Mediterranean coast await. Barcelona port guide Search cruises visiting Barcelona

Barcelona photo — Day 6 Apr 11, 2027 Barcelona 09:00 – 18:00 9.0 hrs ashore On the northeast coast of Spain, overlooking the Mediterranean, Barcelona is a vibrant port city, packed with centuries of iconic art and architecture—Gaudí and Picasso both called it home—and lined with sunny white-sand beaches. Explore the Catalan capital's tourist attractions and historic neighborhoods, Modernisme and world-renowned art museums, galleries and local crafts shops—some of which are centuries old and stock traditional Catalan wares. After you see the sights, there are lively tapas bars around every corner where you can stop for a drink, a café amb llet (Catalan for espresso with steamed milk) or a snack, no matter the hour. Green spaces for picnics, long walks and respite from the hustle and bustle are scattered throughout Barcelona's attractions: There's Gaudí's mosaic-decorated park, a neoclassical maze at the Laberint d'Horta, as well as plenty of high places (mountains, monuments and edifices) where sightseeing visitors can take in the view. A short trip from Barcelona by car or train, luxury outlets, cava wineries, a mountaintop abbey and the sandy beaches of the Mediterranean coast await. Barcelona port guide Search cruises visiting Barcelona

Day 7 Apr 12, 2027 Marseille, France 08:00 – 16:00 8.0 hrs ashore Marseille is the second largest city in France after Paris. It is also one of the oldest continuously inhabited cities in the Mediterranean. Cave paintings in the nearby Calanques are estimated to be 30,000 years old, and remains of brick habitations date from 6,000 BCE. The more recent history begins with a Hellenic port in about 600 BCE, some remains of which are on view at the city’s History Museum. It has been one of the world’s major seaports almost from its founding, and served as the main European terminus of the French colonial empire in Africa and the Far East. It is located in the Provence-Alpes-Cote d’Azur region and is the capital of the Bouches-du-Rhone department. On an island in the expansive bay of Marseille stands the prison of Chateau d’If made famous by the Alexandre Dumas novel “The Count of Monte Cristo.” The Vieux-Port with its atmospheric buildings and wharves is the area where visitors can search for the perfect example of the local specialty bouillabaisse, a rich fish stew containing at least three, and often more varieties of local fishes. Marseille’s newly renovated port at the venerable Joliette Docks is situated very close to the striking Cathédrale de la Major and the fascinating collections at the Museum of African, Oceanic and American Indian Arts. Marseille, France port guide Search cruises visiting Marseille, France

Marseille, France photo — Day 7 Apr 12, 2027 Marseille, France 08:00 – 16:00 8.0 hrs ashore Marseille is the second largest city in France after Paris. It is also one of the oldest continuously inhabited cities in the Mediterranean. Cave paintings in the nearby Calanques are estimated to be 30,000 years old, and remains of brick habitations date from 6,000 BCE. The more recent history begins with a Hellenic port in about 600 BCE, some remains of which are on view at the city’s History Museum. It has been one of the world’s major seaports almost from its founding, and served as the main European terminus of the French colonial empire in Africa and the Far East. It is located in the Provence-Alpes-Cote d’Azur region and is the capital of the Bouches-du-Rhone department. On an island in the expansive bay of Marseille stands the prison of Chateau d’If made famous by the Alexandre Dumas novel “The Count of Monte Cristo.” The Vieux-Port with its atmospheric buildings and wharves is the area where visitors can search for the perfect example of the local specialty bouillabaisse, a rich fish stew containing at least three, and often more varieties of local fishes. Marseille’s newly renovated port at the venerable Joliette Docks is situated very close to the striking Cathédrale de la Major and the fascinating collections at the Museum of African, Oceanic and American Indian Arts. Marseille, France port guide Search cruises visiting Marseille, France

Pricing

Lowest fare we've tracked over the observed 91-day span: $1,332 · range $1,332–$1,437

Lower than 64% of peers This longer-duration sailing's from-price per night is lower than 64% of comparable sailings.

same cruise line and duration · from-price per night · as of Jun 23, 2026 · Broader cohort: same cruise line and duration, compared by from-price per night.

Current prices

Per person · 2 guests · incl. taxes & fees

Inside

from $1,332

$111 / night

Fare rows

JUNIOR INTERIOR FANTASTICA

Cabin grade

Available

from $1,332

$111 / night

per person · incl. taxes

JUNIOR INTERIOR FANTASTICA

Cabin grade

Available

from $1,348

$112 / night

per person · incl. taxes

JUNIOR INTERIOR FANTASTICA

Cabin grade

Available

from $1,980

$165 / night

per person · incl. taxes

JUNIOR INTERIOR FANTASTICA

Cabin grade

Available

from $1,996

$166 / night

per person · incl. taxes

JUNIOR INTERIOR FANTASTICA

Cabin grade

Available

from $2,829

$235 / night

per person · incl. taxes

JUNIOR INTERIOR FANTASTICA

Cabin grade

Available

from $2,861

$238 / night

per person · incl. taxes

Oceanview

from $1,624

$135 / night

Fare rows

JUNIOR OCEAN VIEW FANTASTICA

Cabin grade

Available

from $1,624

$135 / night

per person · incl. taxes

JUNIOR OCEAN VIEW FANTASTICA

Cabin grade

Available

from $1,642

$136 / night

per person · incl. taxes

PREMIUM OCEAN VIEW FANTASTICA

Cabin grade

Available

from $1,710

$142 / night

per person · incl. taxes

JUNIOR OCEAN VIEW FANTASTICA

Cabin grade

Available

from $2,272

$189 / night

per person · incl. taxes

JUNIOR OCEAN VIEW FANTASTICA

Cabin grade

Available

from $2,290

$190 / night

per person · incl. taxes

PREMIUM OCEAN VIEW FANTASTICA

Cabin grade

Available

from $2,358

$196 / night

per person · incl. taxes

JUNIOR OCEAN VIEW FANTASTICA

Cabin grade

Available

from $3,413

$284 / night

per person · incl. taxes

JUNIOR OCEAN VIEW FANTASTICA

Cabin grade

Available

from $3,449

$287 / night

per person · incl. taxes

PREMIUM OCEAN VIEW FANTASTICA

Cabin grade

Available

from $3,585

$298 / night

per person · incl. taxes

Balcony

Not available

Suite

from $2,502

$208 / night

Fare rows

DELUXE SUITE AUREA

Cabin grade

Available

from $2,502

$208 / night

per person · incl. taxes

JUNIOR SUITE AUREA

Cabin grade

Available

from $2,604

$217 / night

per person · incl. taxes

DELUXE SUITE AUREA

Cabin grade

Available

from $3,150

$262 / night

per person · incl. taxes

JUNIOR SUITE AUREA

Cabin grade

Available

from $3,252

$271 / night

per person · incl. taxes

DELUXE SUITE AUREA

Cabin grade

Available

from $5,169

$430 / night

per person · incl. taxes

JUNIOR SUITE AUREA

Cabin grade

Available

from $5,373

$447 / night

per person · incl. taxes

Prices verified Jun 21, 2026

Prices come from third-party data feeds via MSC Cruises and may differ from the cruise line's current fare. Confirm the final price before booking. How our pricing works

Show all 12 cabin grades

Name	Supplier code	Type
BALCONY BELLA GUARANTEED	BB	Balcony
JUNIOR BALCONY FANTASTICA	BM1	Balcony
INTERIOR BELLA GUARANTEED	IB	Inside
JUNIOR INTERIOR FANTASTICA	IM1	Inside
JUNIOR INTERIOR FANTASTICA	IM2	Inside
OCEAN VIEW BELLA GUARANTEED	OB	Oceanview
PREMIUM OCEAN VIEW FANTASTICA	OL1	Oceanview
JUNIOR OCEAN VIEW FANTASTICA	OM1	Oceanview
JUNIOR OCEAN VIEW FANTASTICA	OM2	Oceanview
JUNIOR OCEAN VIEW WITH OBSTRUCTED VIEW FANTASTICA	OO	Oceanview
DELUXE SUITE AUREA	SR1	Suite
JUNIOR SUITE AUREA	SR2	Suite

Ship

Your ship MSC Sinfonia 5★ **65,542** GT **2,546** guests Built **2001** MSC Sinfonia pays homage to the symphonies of the great composers in a thoroughly modern reinterpretation of the classic cruise experience. Stylish designer interiors combine clean lines and every modern comfort with the warmth of traditional natural wood, brass and marble, bringing each stunning venue on this ship its own unique feel. MSC Sinfonia ship guide Search cruises on MSC Sinfonia

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Same itinerary, different dates. Prices per person · incl. taxes & fees.

View	From pp	Departs
	Call for price	Apr 6, 2027Voyage SX20270406GOAGOA

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Itinerary

Pricing

Current prices

Inside

Oceanview

Balcony

Suite

Price history

Ship

Similar cruises

Other sailing dates

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