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21-night US West Coast cruise: Vancouver, Canada to Fort Lauderdale (Port Everglades) on Nieuw Amsterdam

The 21-Day Panama Canal is a 21-night US West Coast cruise aboard Nieuw Amsterdam, operated by Holland America Line. Departing Vancouver, Canada on September 27, 2026 and arriving in Fort Lauderdale on October 18, 2026, the voyage visits 11 ports including San Francisco, California, San Diego, California, Puerto Vallarta, Mexico. Fares start from $2,904 per person.

Length
21 nights
Departs
Sep 27, 2026
Returns
Oct 18, 2026
Ports of call
11
Days at sea
11

Voyage code I671

Vancouver, Canada

21 nights · US West Coast

from $2,904 pp

via CruiseDirect

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Why this route stands out

A closer look at the journey

Vancouver, Canada

Boasting mountains, sea, culture, art and so much more, many cities claim to have it all, but few can back it up like Vancouver. Famously livable, just visiting this highrise city - surrounded by staggering natural beauty - is a thrill. Offering all of the creature comforts of an ultra-modern, worldly metropolis - even downtown has a hint of mountain-freshness to its air - and part of Vancouver's appeal is how easily you can swap the skyscrapers for whale-filled oceans and mountain-punctured skies. View less Head up to the Vancouver Lookout Tower for the ultimate 360-degree views of the city glistening, amid the beautiful embrace of the beckoning wilderness beyond. But what to see first? Art lovers might choose the Vancouver Art Gallery or the Contemporary Art Gallery. Nature lovers might rush for the ferry to visit Vancouver Island - where they can encounter grizzly bears, whales and orcas. Culture vultures, on the other hand, will probably head for the sights and sounds of Canada's biggest Chinatown. From steaming dim sum for lunch to Chinese apothecaries offering herbs to soothe any illness, it’s all here thanks to the migrant workers of the 19th century. The one-of-a-kind treasure of Stanley Park brings wild wonder and natural beauty to this cosmopolitan city's doorstep, and the pine-tree clad park offers isolated trails and amazing views. Wander the Seawall that encircles it - a 20-mile coastal path, full of joggers, whizzing skaters and wandering couples. Grab a bike and cycle between Coal Harbour and Kitsilano Beach. You can top up your tan on the shore, as you soak in the glorious views of the mountains and cityscape from the sands.

San Francisco, California

And if your MSC World Cruise could take you to one of the most fascinating cities in the United States? Making your dream into reality is San Francisco, the next stop on your vacation. In addition to its many tourist attractions, its fame is linked to the high cultural and architectural value it offers, making it the most European of any overseas city. San Francisco is also unique for its particular geographical location, which sees it stand out against green hills while at the same time spreading out directly into the sea, an enchanted view from which you can observe landscapes full of colors and harmony. As soon as you disembark, you will start on one of the signature excursions of MSC. You can admire the symbol of San Francisco: Golden Gate Bridge, the infamous red bridge linking the city to the county of Marin. The structure is one of the wonders of the world, the boldest of its kind ever created by American architecture: its 2700-meter length is supported by two gigantic pylons made to withstand the strong winds and raging currents of the bay. One of the best ways to see this bridge is to cross it on your way to Sausalito, a charming seaside resort also known as the Portofino of America, another stop on your unforgettable trip to this area. Sausalito has a different climate than San Francisco, with beautiful sunshine and weather that is a few degrees warmer creating a pleasant atmosphere, perfect for a trip out of town with a view of the San Francisco skyline and the island of Alcatraz. With MSC Cruises, your vacation becomes an adventure, thanks to a visit to the legendary site of the former maximum security prison. Its name, Alcatraz (which is Spanish for "pelican"), comes from the many pelicans on the spot. It is an attraction that takes you back in time and will introduce you to a piece of San Francisco's history.

Puerto Vallarta, Mexico

Located in the center of Mexico's Pacific coast, Puerto Vallarta is one of the country's most picturesque cities and holiday destinations. Its cobblestone streets and red-roofed, white adobe-style buildings nestle between palm-covered mountains and the vast Banderas Bay. Stretches of white sand beaches are among the best in Mexico and the climate is consistently warm and sunny. For years, vacationers who had discovered the beauty of Puerto Vallarta tried to keep the "good news" from spreading. The arrival of a major film company and two of the world's best-known stars, Elizabeth Taylor and Richard Burton, changed Puerto Vallarta from a laid-back town to a famous getaway destination almost overnight. In addition to its visual appeal, Puerto Vallarta offers a variety of cultural entertainment and a lively nightlife. Take time to see the sights of the city. Downtown spreads around the small Isla Cuale, which lies in the middle of the Cuale River; the heart of the city is a few blocks north around the Municipal Square. A crown-topped cathedral, dedicated to the Virgin of Guadalupe, rises behind the square; a wide seaside promenade, known as the Malecon, hugs the oceanfront. A seahorse statue welcomes visitors to the downtown beach area. The statue and the prominent church tower have become symbols of Puerto Vallarta, or PV as locals call their town for short. Puerto Vallarta grew from an existing fishing village with a history dating back some 100 years. Because of its veritable heritage as a Mexican pueblo, the town tends to offer more of the country's artistic and cultural tradition than other Mexican resorts. The origin of the charro (traditional costume), the national beverage tequila and the typical music of the mariachi bands are credited to Puerto Vallarta. It is considered the most Mexican of all the country's resort towns.

Price tracking

Today’s fare, in context

Price history

Cheaper than 35%
90 days
Fare details

Fare details

Per person · taxes & fees included
Current fares
Verified 14 hours ago
Inside
$2,904
Oceanview
$3,004
Balcony
$3,404
Tracked range
157 days
Price history by cabin type
CabinCurrentLowestHighest
Inside $2,904 $2,104 on Jun 2 $3,669 on Mar 30
Oceanview $3,004 $3,004 on Aug 2 $4,104 on Jun 7
Balcony $3,404 $3,004 on Jun 4 $5,104 on Jun 5
Suite $8,569 $5,204 on Jun 4 $21,964 on Aug 11
Cabin grades
34 total
Verandah StateroomBalcony · V
Verandah StateroomBalcony · VA
Verandah StateroomBalcony · VB
Verandah StateroomBalcony · VC
Verandah StateroomBalcony · VD
Verandah StateroomBalcony · VE
Verandah StateroomBalcony · VF
Verandah StateroomBalcony · VH
Verandah Spa StateroomBalcony · VQ
Large Interior StateroomInside · I
Interior Spa StateroomInside · IQ
Large/Standard Inside StateroomInside · J
Large/Standard Inside StateroomInside · K
Standard Interior StateroomInside · L
Standard Interior StateroomInside · M
Standard Interior StateroomInside · MM
Standard Interior StateroomInside · N
Large Ocean view StateroomOceanview · C
Large Ocean view Spa StateroomOceanview · CQ
Large Ocean view StateroomOceanview · D
Large Ocean view StateroomOceanview · DD
Large Ocean view StateroomOceanview · E
Large Ocean view StateroomOceanview · F
Large Ocean view Stateroom (Partial Sea View)Oceanview · G
Large Ocean view Stateroom (Fully Obstructed View)Oceanview · H
Large Ocean view Stateroom (Fully Obstructed View)Oceanview · HH
Pinnacle SuiteSuite · PS
Neptune SuiteSuite · SA
Neptune SuiteSuite · SB
Neptune SuiteSuite · SC
Neptune Spa SuiteSuite · SQ
Signature SuiteSuite · SS
Signature SuiteSuite · SY
Signature SuiteSuite · SZ

○ = last seen (sold out or delisted). · Verified 14 hours ago.

Lowest fares with no residency, age, or service requirement — verify eligibility at booking. How our pricing works

Current prices

Per person · 2 guests · incl. taxes & fees

Inside

from $2,904

$138 / night

Fare rows

Standard Interior Stateroom

Cabin grade

Available

from $2,904

$138 / night

per person · incl. taxes & fees

Standard Interior Stateroom

Cabin grade

Available

from $3,009

$143 / night

per person · incl. taxes & fees

Standard Interior Stateroom

Cabin grade

Available

from $4,329

$206 / night

per person · incl. taxes & fees

Standard Interior Stateroom

Cabin grade

Available

from $4,359

$207 / night

per person · incl. taxes & fees

Standard Interior Stateroom

Cabin grade

Available

from $4,389

$209 / night

per person · incl. taxes & fees

Large/Standard Inside Stateroom

Cabin grade

Available

from $4,419

$210 / night

per person · incl. taxes & fees

Large/Standard Inside Stateroom

Cabin grade

Available

from $4,449

$211 / night

per person · incl. taxes & fees

Oceanview

from $3,004

$143 / night

Fare rows

Large Ocean view Stateroom (Fully Obstructed View)

Cabin grade

Available

from $3,004

$143 / night

per person · incl. taxes & fees

Large Ocean view Stateroom

Cabin grade

Available

from $3,104

$147 / night

per person · incl. taxes & fees

Large Ocean view Stateroom (Fully Obstructed View)

Cabin grade

Available

from $3,109

$148 / night

per person · incl. taxes & fees

Large Ocean view Stateroom

Cabin grade

Available

from $3,209

$152 / night

per person · incl. taxes & fees

Large Ocean view Stateroom (Fully Obstructed View)

Cabin grade

Available

from $4,459

$212 / night

per person · incl. taxes & fees

Large Ocean view Stateroom (Partial Sea View)

Cabin grade

Available

from $4,529

$215 / night

per person · incl. taxes & fees

Large Ocean view Stateroom

Cabin grade

Available

from $4,539

$216 / night

per person · incl. taxes & fees

Large Ocean view Stateroom

Cabin grade

Available

from $4,609

$219 / night

per person · incl. taxes & fees

Large Ocean view Stateroom

Cabin grade

Available

from $4,679

$222 / night

per person · incl. taxes & fees

Large Ocean view Stateroom

Cabin grade

Available

from $4,749

$226 / night

per person · incl. taxes & fees

Large Ocean view Spa Stateroom

Cabin grade

Available

from $4,819

$229 / night

per person · incl. taxes & fees

Balcony

from $3,404

$162 / night

Fare rows

Verandah Stateroom

Cabin grade

Available

from $3,404

$162 / night

per person · incl. taxes & fees

Verandah Stateroom

Cabin grade

Available

from $3,509

$167 / night

per person · incl. taxes & fees

Verandah Stateroom

Cabin grade

Available

from $4,919

$234 / night

per person · incl. taxes & fees

Verandah Stateroom

Cabin grade

Available

from $5,039

$239 / night

per person · incl. taxes & fees

Verandah Stateroom

Cabin grade

Available

from $5,159

$245 / night

per person · incl. taxes & fees

Verandah Stateroom

Cabin grade

Available

from $5,279

$251 / night

per person · incl. taxes & fees

Verandah Stateroom

Cabin grade

Available

from $5,399

$257 / night

per person · incl. taxes & fees

Verandah Stateroom

Cabin grade

Available

from $5,519

$262 / night

per person · incl. taxes & fees

Verandah Stateroom

Cabin grade

Available

from $5,639

$268 / night

per person · incl. taxes & fees

Verandah Spa Stateroom

Cabin grade

Available

from $5,759

$274 / night

per person · incl. taxes & fees

Suite

Not available

Prices verified Sep 1, 2026

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The journey

21 nights, in order

Vancouver, Canada

Day 1 Sep 27, 2026

Vancouver, Canada

Boasting mountains, sea, culture, art and so much more, many cities claim to have it all, but few can back it up like Vancouver.

Explore Vancouver, Canada

Day by day

The full itinerary

24 scheduled calls
Nieuw Amsterdam

Your ship

Nieuw Amsterdam

The second of Holland America’s Signature Class ships, Nieuw Amsterdam, celebrates historic New York City with an inspired design and art collection. While on board, rejuvenate in the tranquil Spa & Salon, play pickleball at sea, or enjoy a tantalizing meal at fine dining restaurants. When you’re in the mood for music, Billboard Onboard fills the room with chart-topping hits.

5★ 86,700 GT 2,106 Passengers Built 2010
Nieuw Amsterdam ship guide Search cruises on Nieuw Amsterdam

Deck plans

Deck plan for DECK 1 - MAIN DECK

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from $2,904 pp

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