16-night Transatlantic cruise: Genoa, Italy to La Romana on MSC Opera
The Msc Grand Voyages from Genoa is a 16-night Transatlantic cruise aboard MSC Opera, operated by MSC Cruises. Departing Genoa, Italy on October 31, 2026 and arriving in La Romana on November 16, 2026, the voyage visits 8 ports including Marseille, France, Barcelona, Tangier, Morocco. Fares start from $1,729 per person.
Fixed editorial images from the places on this itinerary. They stay stable each time you return to this sailing.
Genoa, Italy
Genoa is marvellously eclectic, vibrant and full of rough-edged style; it’s a great cruise excursion.
Indeed “La Superba” (The Superb), as it was known at the height of its authority as a Mediterranean superpower, boasts more zest and intrigue than all the surrounding coastal resorts put together.
During a holiday to Genoa you can explore its old town: a dense and fascinating warren of medieval alleyways home to large palazzi built in the sixteenth and seventeenth centuries by Genoa’s wealthy mercantile families and now transformed into museums and art galleries. You should seek out the Cattedrale di San Lorenzo, the Palazzo Ducale, and the Renaissance palaces of Via Garibaldi which contain the cream of Genoa’s art collections, as well as furniture and decor from the grandest days of the city’s past, when its ships sailed to all corners of the Mediterranean Sea.
The Acquario di Genova is the city’s pride and joy, parked like a giant ocean liner on the waterfront, with seventy tanks housing sea creatures from all the world’s major habitats, including the world’s biggest reconstruction of a Caribbean coral reef. It’s a great aquarium by any standards, the second largest in Europe by capacity, and boasts a fashionably ecology-conscious slant and excellent background information in Italian and English.
Just 35 km south of Genoa, there’s no denying the appeal of Portofino, tucked into a protected inlet surrounded by lush cypress- and olive-clad slopes. It’s an A-list resort that has been attracting high-flying bankers, celebs and their hangers-on for years, as evidenced by the flotillas of giant yachts usually anchored just outside. It’s a tiny place that is attractive yet somehow off-putting at the same time, with a quota of fancy shops, bars and restaurants for a place twice its size.
Marseille, France
Marseille is the second largest city in France after Paris. It is also one of the oldest continuously inhabited cities in the Mediterranean. Cave paintings in the nearby Calanques are estimated to be 30,000 years old, and remains of brick habitations date from 6,000 BCE. The more recent history begins with a Hellenic port in about 600 BCE, some remains of which are on view at the city’s History Museum. It has been one of the world’s major seaports almost from its founding, and served as the main European terminus of the French colonial empire in Africa and the Far East. It is located in the Provence-Alpes-Cote d’Azur region and is the capital of the Bouches-du-Rhone department. On an island in the expansive bay of Marseille stands the prison of Chateau d’If made famous by the Alexandre Dumas novel “The Count of Monte Cristo.” The Vieux-Port with its atmospheric buildings and wharves is the area where visitors can search for the perfect example of the local specialty bouillabaisse, a rich fish stew containing at least three, and often more varieties of local fishes. Marseille’s newly renovated port at the venerable Joliette Docks is situated very close to the striking Cathédrale de la Major and the fascinating collections at the Museum of African, Oceanic and American Indian Arts.
Barcelona
On the northeast coast of Spain, overlooking the Mediterranean, Barcelona is a vibrant port city, packed with centuries of iconic art and architecture—Gaudí and Picasso both called it home—and lined with sunny white-sand beaches. Explore the Catalan capital's tourist attractions and historic neighborhoods, Modernisme and world-renowned art museums, galleries and local crafts shops—some of which are centuries old and stock traditional Catalan wares. After you see the sights, there are lively tapas bars around every corner where you can stop for a drink, a café amb llet (Catalan for espresso with steamed milk) or a snack, no matter the hour. Green spaces for picnics, long walks and respite from the hustle and bustle are scattered throughout Barcelona's attractions: There's Gaudí's mosaic-decorated park, a neoclassical maze at the Laberint d'Horta, as well as plenty of high places (mountains, monuments and edifices) where sightseeing visitors can take in the view. A short trip from Barcelona by car or train, luxury outlets, cava wineries, a mountaintop abbey and the sandy beaches of the Mediterranean coast await.
Prices come from third-party data feeds via MSC Cruises and may differ from the cruise line's current fare. Confirm the final price before booking. How our pricing works
Lowest fares with no residency, age, or service requirement — verify eligibility at booking. How our pricing works
Not ready to book?
Get price alerts
We’ll email you when fares drop or return.
Check your email to finish
We sent a confirmation link to your inbox. Your alert is not on yet — click that link to switch it on.
With its impressive array of new features and facilities, MSC Opera is now even better equipped to satisfy the needs of our guests.
We’ve added spacious new cabins with balconies offering superb panoramic views and we have enlarged the restaurant and buffet areas to serve up an even greater variety of culinary treats. There is even a new 330 m² music and dance area for guests to show off their moves.
We count visits anonymously without cookies. Accept cookies to let us remember you across visits and connect activity if you create an account, or decline and we'll still count you anonymously. Read our privacy policy
ESC
The Captain
I'm the Captain. Tell me what you're after — "Caribbean under $2,000" or "7 nights from Miami" — and I'll find the sailing and its price history.
