Guayaquil to San Juan

The Guayaquil to San Juan is a 9-night North America cruise aboard Crystal Symphony, operated by Crystal Cruises. Departing Guayaquil on September 5, 2026, the voyage visits 6 ports. Fares start from $3,883 per person.

Length: 9 nights
Departs: Sep 5, 2026
Returns: Sep 14, 2026
Ports of call: 6
Days at sea: 2

from $3,883

$431 / night per person, incl. taxes & fees

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Itinerary

Day 1 Sep 5, 2026 Guayaquil Departs 19:00 The second major jumping off point for the Galapagos Islands after Quito, this is a little city with a big heart. A sea port first and foremost, the city’s personality has been founded on that, and all the better it is for it too. Almost Caribbean in feeling, the clement climate coupled with the intermingling rhythms floating from the windows and abundance of fresh seafood make this a very tropical destination. View less Once not even considered by the travel books as a potential destination in its own right, the city has undergone something of a resurgence in the past few years. Proud Guayaquileños will not hestitate to point out the Malecón or the exciting new riverfront promenade, once a no-go area after dark, now happily (and hippily) lined with museums, restaurants, shops, and ongoing entertainment. The new airport and urban transportation network are also lauded to the happy tourists who find themselves here. As the largest and most populous city in Ecuador as well as being the commercial centre, it would only be natural that the city would have some kind of modern architecture, but it is the colourful favelas, or to use their real name guasmos, that cling to the side of the hillside like limpets that really catch your eye. A blend of old and new, the first inhabitants can be traced back to 1948 when the government cleared the area for affordable housing, these shanty towns are witness to the social and political particularities that Guayaquil has faced in the past. Guayaquil port guide Search cruises visiting Guayaquil

Day 5 Sep 9, 2026 Panama Canal Panama is synonymous with the Panama Canal. While Panama connects Central America to South America, the Panama Canal, which opened in 1914, connects the Caribbean Sea with the Pacific Ocean. The channel reduces shipping time and currently connects 160 countries and 1,700 ports around the world. Hailed as an engineering marvel, the artificial waterway with its elaborate lock system is one of the greatest achievements of the 20th century. Arriving on an MSC Caribbean and Antilles cruise into Colón, Panama’s gateway city, you’ll encounter the irresistible juxtaposition of the ancient and modern, the artificial and natural, as enormous computerized container ships transiting the canal slice through primeval rainforests teeming with fluorescent frogs and elusive wild cats. Book an MSC excursion to hop on a ferry that will take you along the length of the Panama Canal, through lakes and locks and past the Centennial and Americas bridges. Finally, you will arrive at Pacific port at the entrance to the Panama Canal, and then enjoy a 90-minute bus ride back to your ship. Panama Canal port guide Search cruises visiting Panama Canal

Day 6 Sep 10, 2026 Cartagena, Colombia 10:00 – 19:00 9.0 hrs ashore Cobbled streets, balconies overflowing with blooming bougainvillea and pastel-coloured buildings lining elegant plazas make Cartagena in Colombia one of the Caribbean's most photogenic cities, and a memorable stop on an MSC Caribbean and Antilles cruise. Founded in 1533, this Spanish colonial city, a UNESCO World Heritage Site, is steeped in history. Its location made it a popular target for plunderers and English pirates, and arguably features the most impressive collection of forts in the Caribbean. Today the city is eager to share its treasures with modern visitors. Magnificent colonial structures such as the 16th-century Santa Catalina Cathedral, with its striking stuccoes and dome tower, and the three-arch clock gate, the Torre del Reloj, are just two of the many landmarks of this enchanting city dotted with many squares and sidewalk cafés. A wonderful photo stop on our Cartagena City MSC excursion is the San Felipe de Barajas fortress, a marvel of colonial Spanish military engineering. Its construction began in 1536. Slaves la-boured for more than 120 years to erect this fortress - built on high ground with dominating ap-proaches to the city by land and sea to fend off pirates - and its network of tunnels. On yet another MSC excursion, enrich your palate as you learn about the rich aromas and flavours of Colombian coffee. Introduced by the Jesuits in 1723, coffee quickly became a key crop in Colombia, which is now one of the top producers of Arabica coffee in the world. Colombia is also the world’s top producer of emeralds. If jewellery and gems fascinate you, learn all about these green precious stones and make your own emerald-studded jewellery in sterling silver during a hands-on MSC excursion that guides you step-by-step. And you don’t need to go far to explore nature. An MSC excursion takes you by canoe through mangrove tunnels to Ciénaga de la Virgen, where you can witness a diversity of birds from king-fishers and white herons to pelicans and pink-feathered roseate spoonbills. Cartagena, Colombia port guide Search cruises visiting Cartagena, Colombia

Cartagena, Colombia photo — Day 6 Sep 10, 2026 Cartagena, Colombia 10:00 – 19:00 9.0 hrs ashore Cobbled streets, balconies overflowing with blooming bougainvillea and pastel-coloured buildings lining elegant plazas make Cartagena in Colombia one of the Caribbean's most photogenic cities, and a memorable stop on an MSC Caribbean and Antilles cruise. Founded in 1533, this Spanish colonial city, a UNESCO World Heritage Site, is steeped in history. Its location made it a popular target for plunderers and English pirates, and arguably features the most impressive collection of forts in the Caribbean. Today the city is eager to share its treasures with modern visitors. Magnificent colonial structures such as the 16th-century Santa Catalina Cathedral, with its striking stuccoes and dome tower, and the three-arch clock gate, the Torre del Reloj, are just two of the many landmarks of this enchanting city dotted with many squares and sidewalk cafés. A wonderful photo stop on our Cartagena City MSC excursion is the San Felipe de Barajas fortress, a marvel of colonial Spanish military engineering. Its construction began in 1536. Slaves la-boured for more than 120 years to erect this fortress - built on high ground with dominating ap-proaches to the city by land and sea to fend off pirates - and its network of tunnels. On yet another MSC excursion, enrich your palate as you learn about the rich aromas and flavours of Colombian coffee. Introduced by the Jesuits in 1723, coffee quickly became a key crop in Colombia, which is now one of the top producers of Arabica coffee in the world. Colombia is also the world’s top producer of emeralds. If jewellery and gems fascinate you, learn all about these green precious stones and make your own emerald-studded jewellery in sterling silver during a hands-on MSC excursion that guides you step-by-step. And you don’t need to go far to explore nature. An MSC excursion takes you by canoe through mangrove tunnels to Ciénaga de la Virgen, where you can witness a diversity of birds from king-fishers and white herons to pelicans and pink-feathered roseate spoonbills. Cartagena, Colombia port guide Search cruises visiting Cartagena, Colombia

Day 8 Sep 12, 2026 Santo Domingo, Dominican Republic 08:00 – 19:00 11.0 hrs ashore The Dominican Republic’s capital is the largest city by population in the Caribbean region. It is also the oldest continuously occupied European city in the Americas. It was founded in 1496 by Bartolomeo Columbus, and named La Nueva Isabel after his royal Spanish patron. The settlement became the gateway to the Americas for the Spanish conquest, and most of the expeditions that delineated the rest of the New World originated there, taking advantage of the deepwater delta of the Ozama River. Today the city’s Colonial Zone is a UNESCO World Heritage Site and contains a remarkable legacy of 16th Century buildings, including the first cathedral in America, Catedral de Santa Maria la Menor; the first monastery, Monasterio de San Francisco, the first castle, Alacazar Colón and the first fortress: Fortaleza Ozama. The Museo de Casas Reales is another treasury of significant buildings. The Dominican dictator Trujillo renamed the city after himself between 1936 and 1961, but it regained its previous name following his assassination. The city is a fascinating and colorful place, revealing a vibrant hybrid culture with recognizable influences from native Taino, African and European ancestry. Many visitors purchase souvenir jewelry created out of the fossil amber mined on the island of Hispaniola, which the Dominican Republic shares with the nation of Haiti. Santo Domingo, Dominican Republic port guide Search cruises visiting Santo Domingo, Dominican Republic

Santo Domingo, Dominican Republic photo — Day 8 Sep 12, 2026 Santo Domingo, Dominican Republic 08:00 – 19:00 11.0 hrs ashore The Dominican Republic’s capital is the largest city by population in the Caribbean region. It is also the oldest continuously occupied European city in the Americas. It was founded in 1496 by Bartolomeo Columbus, and named La Nueva Isabel after his royal Spanish patron. The settlement became the gateway to the Americas for the Spanish conquest, and most of the expeditions that delineated the rest of the New World originated there, taking advantage of the deepwater delta of the Ozama River. Today the city’s Colonial Zone is a UNESCO World Heritage Site and contains a remarkable legacy of 16th Century buildings, including the first cathedral in America, Catedral de Santa Maria la Menor; the first monastery, Monasterio de San Francisco, the first castle, Alacazar Colón and the first fortress: Fortaleza Ozama. The Museo de Casas Reales is another treasury of significant buildings. The Dominican dictator Trujillo renamed the city after himself between 1936 and 1961, but it regained its previous name following his assassination. The city is a fascinating and colorful place, revealing a vibrant hybrid culture with recognizable influences from native Taino, African and European ancestry. Many visitors purchase souvenir jewelry created out of the fossil amber mined on the island of Hispaniola, which the Dominican Republic shares with the nation of Haiti. Santo Domingo, Dominican Republic port guide Search cruises visiting Santo Domingo, Dominican Republic

Day 9 Sep 13, 2026 Punta Cana, Domnican Republic 08:00 – 18:00 10.0 hrs ashore Let yourself relax and experience the best of Punta Cana, where sugar-fine sands, sapphire surf, verdant green palms and the warm kiss of the tropical sun are sure to leave you in a tranquil state of mind. Ready for more action? Discover the Parque Nacional Los Haitises, which translates to "land of the mountains." It's the perfect place to kayak amid verdant mangroves, hike along beautiful waterfalls, and drink in the lush beauty of subtropical ferns, bromeliads and bamboo. Or, learn about the region's wildlife on a leisurely horseback ride through the gorgeous countryside. You may also want to explore a fascinating limestone cave, perhaps even spot ancient petroglyphs. Whatever you choose to do, Punta Cana offers something unforgettable for everyone.

Day 10 Sep 14, 2026 San Juan, Puerto Rico Arrives 07:00 Blessed with some of the oldest buildings in the Western Hemisphere, San Juan, Puerto Rico’s cap-ital, is romantically charming with its bright pastel Spanish colonial facades, wrought-iron balconies abloom with flowers, narrow cobblestone streets and beloved park squares. Once you arrive on an MSC Caribbean and Antilles cruise at the port, explore Old San Juan (Viejo San Juan), a UNESCO World Heritage district, widely renowned for the fortresses of Castillo San Felipe del Morro and the Castillo San Cristóbal. The old town occupies the headland of a 2.5-mile-long island (connected by bridge to the mainland) that shelters San Juan Bay, for centuries a key port in the New World. It was originally known as Puerto Rico, or “rich port,” because its location made it the perfect stop for shipping. Several MSC excursions offer walking tours that let you soak up amazing views of San Juan, while making cultural discoveries of a lifetime. Wander through the old town along the Paseo de la Princesa, San Juan’s oldest tree-lined avenue; head up its southern city wall, La Muralla, which until the late 19th century encircled all of Old San Juan with sandstone; and tour the 16th-century fortress of El Morro, with its six different lines of defence. Take a coffee-tasting walking tour to explore Puerto Rico’s rich coffee culture, and learn how the island’s rich volcanic soil and climate have contributed to the rise of coffee as one of its main crops. Taste a delicious cup of freshly brewed Puerto Rican café con leche, learn about the island's historical ties with the caffeine-rich beverage, and explore how coffee and the church are connected on this MSC excursion through the streets of Old San Juan. Or savour San Juan’s culinary delights, in a Martha Stewart excursion curated exclusively for MSC that will have you tasting local cuisine and drinks at five destinations along the route through the fortified colonial city. From Puerto Rican fritters at historic El Convento Hotel, to chocolate tasting at a fourth-generation chocolatier, you won’t want to miss this tour, which ends at La Casita de Rones for a rum lesson and a piña colada, the national drink of Puerto Rico. With more than 80% of the world's rum coming from Puerto Rico, delve deeper into the spirit on an MSC excursion to Casa Bacardí in the town of Cataño. Discover the story behind Bacardí’s legendary cocktails, sniff the products on display and learn about the rum-making process including wood barrelling, ageing and finishing. For the grand finale, enjoy a fascinating mixology show. Nature lovers will not want to miss a visit to El Yunque, the only tropical rainforest in the U.S. territory and one of Puerto Rico's finest spots of natural beauty. Marvel at its small horsetail waterfalls, giant ferns and tropical hardwoods. For an enchanting experience, kayak into the enchanting bioluminescent bay at Laguna Grande of Fajardo on another MSC excursion. Under the blanket of the night sky and the lighthouse of Fajardo, paddle through the water and watch it glow with the bioluminescence of millions and millions of tiny organisms. San Juan, Puerto Rico port guide Search cruises visiting San Juan, Puerto Rico

San Juan, Puerto Rico photo — Day 10 Sep 14, 2026 San Juan, Puerto Rico Arrives 07:00 Blessed with some of the oldest buildings in the Western Hemisphere, San Juan, Puerto Rico’s cap-ital, is romantically charming with its bright pastel Spanish colonial facades, wrought-iron balconies abloom with flowers, narrow cobblestone streets and beloved park squares. Once you arrive on an MSC Caribbean and Antilles cruise at the port, explore Old San Juan (Viejo San Juan), a UNESCO World Heritage district, widely renowned for the fortresses of Castillo San Felipe del Morro and the Castillo San Cristóbal. The old town occupies the headland of a 2.5-mile-long island (connected by bridge to the mainland) that shelters San Juan Bay, for centuries a key port in the New World. It was originally known as Puerto Rico, or “rich port,” because its location made it the perfect stop for shipping. Several MSC excursions offer walking tours that let you soak up amazing views of San Juan, while making cultural discoveries of a lifetime. Wander through the old town along the Paseo de la Princesa, San Juan’s oldest tree-lined avenue; head up its southern city wall, La Muralla, which until the late 19th century encircled all of Old San Juan with sandstone; and tour the 16th-century fortress of El Morro, with its six different lines of defence. Take a coffee-tasting walking tour to explore Puerto Rico’s rich coffee culture, and learn how the island’s rich volcanic soil and climate have contributed to the rise of coffee as one of its main crops. Taste a delicious cup of freshly brewed Puerto Rican café con leche, learn about the island's historical ties with the caffeine-rich beverage, and explore how coffee and the church are connected on this MSC excursion through the streets of Old San Juan. Or savour San Juan’s culinary delights, in a Martha Stewart excursion curated exclusively for MSC that will have you tasting local cuisine and drinks at five destinations along the route through the fortified colonial city. From Puerto Rican fritters at historic El Convento Hotel, to chocolate tasting at a fourth-generation chocolatier, you won’t want to miss this tour, which ends at La Casita de Rones for a rum lesson and a piña colada, the national drink of Puerto Rico. With more than 80% of the world's rum coming from Puerto Rico, delve deeper into the spirit on an MSC excursion to Casa Bacardí in the town of Cataño. Discover the story behind Bacardí’s legendary cocktails, sniff the products on display and learn about the rum-making process including wood barrelling, ageing and finishing. For the grand finale, enjoy a fascinating mixology show. Nature lovers will not want to miss a visit to El Yunque, the only tropical rainforest in the U.S. territory and one of Puerto Rico's finest spots of natural beauty. Marvel at its small horsetail waterfalls, giant ferns and tropical hardwoods. For an enchanting experience, kayak into the enchanting bioluminescent bay at Laguna Grande of Fajardo on another MSC excursion. Under the blanket of the night sky and the lighthouse of Fajardo, paddle through the water and watch it glow with the bioluminescence of millions and millions of tiny organisms. San Juan, Puerto Rico port guide Search cruises visiting San Juan, Puerto Rico

Pricing

Lowest fare we've tracked over the observed 92-day span: $3,883 · range $3,883–$3,960

Lower than 71% of peers This longer-duration sailing's from-price per night is lower than 71% of comparable sailings.

same cruise line and duration · from-price per night · as of Jun 24, 2026 · Broader cohort: same cruise line and duration, compared by from-price per night.

Current prices

Per person · 2 guests · incl. taxes & fees

Inside

Not available

Oceanview

from $3,883

$431 / night

Fare rows

Double Guest Room with Ocean View

Cabin grade

Available

from $3,883

$431 / night

per person · incl. taxes

Double Guest Room with Ocean View

Cabin grade

Available

from $4,036

$448 / night

per person · incl. taxes

Double Guest Room with Ocean View

Cabin grade

Available

from $4,215

$468 / night

per person · incl. taxes

Double Guest Room with Ocean View

Cabin grade

Available

from $4,385

$487 / night

per person · incl. taxes

Single Guest Room with Ocean View

Cabin grade

Available

from $5,355

$595 / night

per person · incl. taxes

Single Guest Room with Ocean View

Cabin grade

Available

from $5,850

$650 / night

per person · incl. taxes

Balcony

from $5,220

$580 / night

Fare rows

Double Guest Room with Veranda

Cabin grade

Available

from $5,220

$580 / night

per person · incl. taxes

Double Guest Room with Veranda

Cabin grade

Available

from $5,400

$600 / night

per person · incl. taxes

Double Guest Room with Veranda

Cabin grade

Available

from $5,700

$633 / night

per person · incl. taxes

Double Guest Room with Veranda

Cabin grade

Available

from $5,900

$655 / night

per person · incl. taxes

Suite

from $5,112

$568 / night

Fare rows

Aquamarine Ocean View Suite

Cabin grade

Available

from $5,112

$568 / night

per person · incl. taxes

Aquamarine Veranda Suite

Cabin grade

Available

from $5,517

$613 / night

per person · incl. taxes

Sapphire Ocean View Suite

Cabin grade

Available

from $5,566

$618 / night

per person · incl. taxes

Aquamarine Ocean View Suite

Cabin grade

Available

from $5,580

$620 / night

per person · incl. taxes

Aquamarine Veranda Suite

Cabin grade

Available

from $6,003

$667 / night

per person · incl. taxes

Aquamarine Veranda Suite

Cabin grade

Available

from $6,030

$670 / night

per person · incl. taxes

Sapphire Ocean View Suite

Cabin grade

Available

from $6,085

$676 / night

per person · incl. taxes

Aquamarine Veranda Suite

Cabin grade

Available

from $6,570

$730 / night

per person · incl. taxes

Sapphire Veranda Suite

Cabin grade

Available

from $6,975

$775 / night

per person · incl. taxes

Sapphire Veranda Suite

Cabin grade

Available

from $7,218

$802 / night

per person · incl. taxes

Sapphire Veranda Suite

Cabin grade

Available

from $7,650

$850 / night

per person · incl. taxes

Sapphire Veranda Suite

Cabin grade

Available

from $7,920

$880 / night

per person · incl. taxes

Junior Crystal Penthouse Suite

Cabin grade

Available

from $12,510

$1,390 / night

per person · incl. taxes

Junior Crystal Penthouse Suite

Cabin grade

Available

from $13,590

$1,510 / night

per person · incl. taxes

Junior Crystal Penthouse Suite

Cabin grade

Available

from $13,800

$1,533 / night

per person · incl. taxes

Junior Crystal Penthouse Suite

Cabin grade

Available

from $15,000

$1,666 / night

per person · incl. taxes

Crystal Penthouse Suite

Cabin grade

Available

from $15,390

$1,710 / night

per person · incl. taxes

Crystal Penthouse Suite

Cabin grade

Available

from $17,000

$1,888 / night

per person · incl. taxes

Prices verified Jun 24, 2026

Prices come from third-party data feeds via Crystal Cruises and may differ from the cruise line's current fare. Confirm the final price before booking. How our pricing works

Show all 14 cabin grades

Name	Supplier code	Type
Double Guest Room with Veranda	CSVF	Balcony
Double Guest Room with Veranda	CSVM	Balcony
Double Guest Room with Ocean View	CSWF	Oceanview
Double Guest Room with Ocean View	CSWM	Oceanview
Single Guest Room with Ocean View	SGWF	Oceanview
Crystal Penthouse Suite	CHV4	Suite
Sapphire Veranda Suite	GSVF	Suite
Sapphire Veranda Suite	GSVM	Suite
Sapphire Ocean View Suite	GSWM	Suite
Junior Crystal Penthouse Suite	RYVF	Suite
Junior Crystal Penthouse Suite	RYVM	Suite
Aquamarine Veranda Suite	SSVF	Suite
Aquamarine Veranda Suite	SSVM	Suite
Aquamarine Ocean View Suite	SSWM	Suite