3-night Mediterranean cruise: Malta to Civitavecchia, Rome on Crystal Serenity
The Valletta to Civitavecchia Rome is a 3-night Mediterranean cruise aboard Crystal Serenity, operated by Crystal Cruises. Departing Malta on September 19, 2026 and arriving in Civitavecchia, Rome on September 22, 2026, the voyage visits 3 ports including Trapani (Sicily), Cagliari. Fares start from $2,600 per person.
Fixed editorial images from the places on this itinerary. They stay stable each time you return to this sailing.
Malta
The UNESCO-protected port of Valletta, the capital of the island of Malta, is one of the must-see stops for every Mediterranean cruise of merit.
You can admire this port, constructed in the second half of the 16th century by the Frenchman Jean de la Valette and moulded by the religious and military Order of Saint John of Jerusalem, from your MSC ship even before disembarking. The over 300 monuments rising in little more than half a square kilometre make this a place with one of the greatest density of historical attractions to visit during a cruise, not mentioning other attractions such as its beaches, seaside locales and restaurants.
An excursion to the island can start right from its capital, Valletta, which enchants the cruise-goer with its famous Maltese balconies, which decorate the facades of houses in its old quarter. Surrounded by a multitude of churches, which the islanders assure are as many as the days of the year, the St. John’s Co-Cathedral is one of Malta’s biggest tourist attractions.
The National Museum of Archaeology, on the other hand, hosts prehistoric artefacts found on the island. By the Grand Harbour, one can visit the underground passages of Auberge de Castille and the beautiful Baracca Gardens, which overlook the harbour; at night, when the city gates would close, its porticoes served as shelter for travellers. To get a taste of the life of Malta’s ancient nobility, visit Casa Rocca Piccola.
A 16th century Palazzo now the residence of the 9th Marquis De Piro, it has period furnishings and has a bomb shelter built for protection against bombings during the Second World War. The set of the film Popeye can still be seen from Malta’s largest beach, as well as the Sanctuary of Our Lady of Mellieha with a fresco of the Blessed Virgin Mary with Christ; according to tradition, Saint Luke, who was shipwrecked on the island with Saint Paul, is the author of this Byzantine-style fresco.
Trapani (Sicily)
Surrounded by glowing turquoise waters and rugged coastline, Trapani invites you to explore western Sicily's ruins, intense flavours, and sun-soaked leisure pursuits. Built on salt and tuna exports, Trapani is experiencing a renaissance, having been lovingly spruced up as a sailing capital, and an international airport bringing in visitors from far and wide. The town looks out over the Egadi Islands, gazing west to witness some of Siciliy's most evocative sunset displays. View less
Start exploring Trapani from its historic core, a dense network of alleys hosting a collection of small shops, restaurants and wine bars. You’ll encounter the Cathedral of San Lorenzo – where colourful artworks are spread below sweeping arches and a beautiful domed roof. Sicily feels like an island on the cusp of continents, and Trapani practically has one foot in Africa, as you soak in its pretty whitewash houses and fusion of foods and arts. Discover the Ancient Greek influence by venturing to rich archaeological sites nearby, like Selinus and Segesta, where the treasures from the past have been unearthed and displayed. Pyramids of white salt rise up at the Riserva Naturale Saline di Trapani e Paceco. These salt marshes and windmills are a symbol of Trapani, and although sea salt production is much less important today, the small white hills remain a Trapani landmark. Look out for the pink flamingos wading in the salt pans below. For beach days, the Egadi Islands can be easily reached from Trapani - Favignana is the largest and most popular.
Cagliari
The serene sea approach to Cagliari is an exquisitely beautiful way to first lay eyes on the city’s mesmerising interplay of colour, spires and domed churches. Sat on Sardinia’s south coast, Cagliari is the island’s largest city, and a sun-blessed escape of beaches, architecture and Mediterranean food – where stress evaporates on contact. That first sight of Cagliari’s mosaic of architecture reveals much about the island’s history, and is a living document of the civilisations and influences that have passed through.
Combining Byzantine churches with crumbling Roman ruins and Pisan towers, it’s an elegant, beguiling place to explore. Usher in the morning with a short, sharp espresso hit, before wandering along to San Benedetto market’s bustle, crammed full of overflowing heaps of local produce. Taste crisp, freshly-baked bread, thin shavings of sheep’s cheese, and ripe red strawberries, as you wander amid the market’s melody of good-natured bartering. The Castello quarter’s tight, flower-draped streets and salmon-hued brick buildings incline up above the Med’s softly lapping waves. Climb Bastione di Saint Remy staircase to Terrazza Umberto’s views of the turquoise Gulf of Angels. Next, Cathedral of Santa Maria awaits, with its marbled interiors, elaborate side chapels and intricately decorated crypt. Once you’ve unravelled Cagliari’s historical tapestry, Poetto Beach invites you to find a spot on almost five miles of uninterrupted sand, met by a dazzling expanse of turquoise water. On a hot summer’s day, soak up some sun before saluting the sunset with an ice cold Spritz at a beachside bar. Spaghetti with salted bottarga and artichokes will keep the good times rolling, perfectly accompanied by a glass of ruby-coloured Cannonau wine.
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