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21-night Mediterranean cruise: Trieste to Civitavecchia, Rome on Oosterdam

The 21-Day Ancient Seas: Adriatic, Greek Isles & Istanbul is a 21-night Mediterranean cruise aboard Oosterdam, operated by Holland America Line. Departing Trieste on September 21, 2027 and arriving in Civitavecchia, Rome on October 12, 2027, the voyage visits 12 ports including Split, Dubrovnik, Santorini. Fares start from $5,964 per person.

Length
21 nights
Departs
Sep 21, 2027
Returns
Oct 12, 2027
Ports of call
12
Days at sea
6

Voyage code O758A

Trieste

21 nights · Mediterranean

from $5,964 pp

via CruiseDirect

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Why this route stands out

A closer look at the journey

Trieste

If you are looking for elegance and culture, the ideal destination is Trieste. An MSC Mediterranean Cruise will take you to the old cafés where you can relive the same atmosphere that inspired many writers, among the Art Nouveau and Neoclassical palaces, or along the Grand Canal. Your MSC Cruise will take you to the "little Vienna on the sea" which is now one of the largest ports in Italy for freight traffic, one of the most cosmopolitan cities on the peninsula. A meeting of peoples, languages and religions that magnify the city's Central European, Slav and Mediterranean soul. One of the MSC Excursions will guide you to visit The Castle of Miramare, residence of Maximilian of Hapsburg and Charlotte of Belgium. A desirable palace for its view of the Gulf of Trieste and unique elegance of the furnishings still visible of the apartments, on the spouses' ground floor and the guests' first floor. Built between 1856 and 1860, it contains a small castle used by the married couple during the construction works in the magnificent richly scented park that surrounds it. Another MSC Excursion will take you to visit the Roman amphitheatre at the foot of the Colle di San Giusto, set among the modern buildings of Trieste, a city with an ancient history. Constructed around the end of the 1st century, it was only brought to light in 1938. Interestingly, it once overlooked the sea. Everything in Trieste faces the sea including Piazza Unità d'Italia, the Piazza Grande, the destination of an MSC Excursion. Strolling along this large rectangle framed on three sides by the city's most famous buildings and the renowned Caffè degli Specchi, stopping under the column of the Statue of Charles VI and idling in front of the Fountain of the Four Continents, are experiences crowned by the view of the sea on the fourth side.

Split

With its seafront cafés and ancient alleyways, shouting stallholders and travellers on the move, bustling, exuberant Split is one of Croatia’s and the Mediterranean’s most compelling cities, it’s easy to see this feeling when you step aground from your MSC cruise. It has a unique historical heritage too, having grown out of the palace built here by the Roman Emperor Diocletian in 295AD. The palace remains Split’s central ingredient, having been gradually transformed into a warren of houses, tenements, churches and chapels by the various peoples who came to live here after Diocletian’s successors had departed. Adapted long ago to serve as Split’s town centre, Diocletian’s Palace is certainly not an archaeological “site”. Although set-piece buildings such as Diocletian’s mausoleum (now the cathedral) and the Temple of Jupiter (now a baptistery) still remain, other aspects of the palace have been tinkered with so much by successive generations that it is no longer recognizable as an ancient Roman structure. Best place to start exploring with an MSC excursion the seaward side of the palace is Split’s broad and lively Riva. Running along the palace’s southern facade, into which shops, cafés and a warren of tiny flats have been built, the Riva is where a large part of the city’s population congregates day and night to meet friends, catch up on gossip or idle away an hour or two in a café. Nearly everything worth seeing in Split is concentrated in the compact Old Town behind the waterfront Riva, made up in part of the various remains and conversions of Diocletian’s Palace itself, and the medieval additions to the west of it. You can walk across this area in about ten minutes, although it would take a lifetime to explore all its nooks and crannies.

Dubrovnik

Croatia’s crowning glory rears up vertically from the tranquil waters of the Adriatic, and Dubrovnik’s daunting fortresses town is a truly imposing sight to behold. Encircled by chunky stone walls so thick and dramatic they could have been purpose-built as a film set, this city’s unmatched old town is the setting for countless films and shows - from Star Wars to Robin Hood, Game of Thrones and every production in-between seeking a truly authentic medieval flavour. This fantasy fortress’s walls - which are no less than 12-metres thick at places - are certainly not just for show, however. They kept Dubrovnik safe when it was a maritime republic and they were besieged as recently as 1991, when Serbian and Montenegrin forces attacked, as Yugoslavia broke apart. Fully restored now, the stone streets of the city take you through a beautiful mosaic of architectural splendour, baroque churches and splashing fountains. Tapering alleys rocket up from the central boulevard of Stradun, offering spectacular views down, but you’ll need to walk the city walls to appreciate the fortress city’s full scale. Banking up sharply to the rear, you can gaze across an ocean of terracotta roofs and church spires, clamouring together before the sparkling Adriatic. Visit the neighbouring fort of Lovrijenac, for another perspective, or swing up to Srd fortress’s glorious panorama on a cable car. Dubrovnik’s streets are crammed with eateries and candlelit tables, where couples splash wine into glasses and enjoy gnocchi mixed with creamy truffle sauces. Nearby beaches like Banje are also close by, and hidden bays reward the intrepid who venture out beyond the old town. Take sunset drinks to sit back and watch as flotillas of sea kayaks roll by, or sail on the pristine waters to explore island gems like Lokrum - where peacocks are the only permanent residents.

Price tracking

Today’s fare, in context

Price history

Cheaper than 78%
30 days
Fare details

Fare details

Per person · taxes & fees included
Current fares
Verified 2 hours ago
Inside
$5,964
Oceanview
$6,284
Balcony
$8,114
Suite
$10,924
Tracked range
164 days
Price history by cabin type
CabinCurrentLowestHighest
Inside $5,964 $5,809 on Mar 25 $5,964 on Aug 2
Oceanview $6,284 $6,029 on Mar 25 $6,284 on Aug 8
Balcony $8,114 $7,629 on Mar 25 $8,114 on Aug 8
Suite $10,924 $10,019 on Jul 28 $10,924 on Aug 24
Cabin grades
29 total
Verandah StateroomBalcony · VA
Verandah StateroomBalcony · VB
Verandah StateroomBalcony · VC
Verandah StateroomBalcony · VD
Verandah StateroomBalcony · VE
Verandah StateroomBalcony · VF
Verandah StateroomBalcony · VH
Large/Standard Inside StateroomInside · I
Large Interior StateroomInside · J
Large/Standard Inside StateroomInside · K
Standard Interior StateroomInside · L
Standard Interior StateroomInside · M
Large/Standard Inside StateroomInside · MM
Standard Interior StateroomInside · N
Large Ocean view StateroomOceanview · C
Large Ocean view StateroomOceanview · D
Large Ocean view StateroomOceanview · DD
Large Ocean view StateroomOceanview · E
Large Ocean view StateroomOceanview · F
Large Ocean view Stateroom (Partial Sea View)Oceanview · G
Large Ocean view Stateroom (Fully Obstructed View)Oceanview · H
Large Ocean view Stateroom (Fully Obstructed View)Oceanview · HH
Pinnacle SuiteSuite · PS
Neptune SuiteSuite · SA
Neptune SuiteSuite · SB
Neptune SuiteSuite · SC
Signature SuiteSuite · SS
Signature SuiteSuite · SY
Signature SuiteSuite · SZ

○ = last seen (sold out or delisted). · Verified 2 hours ago.

Lowest fares with no residency, age, or service requirement — verify eligibility at booking. How our pricing works

Current prices

Per person · 2 guests · incl. taxes & fees

Inside

from $5,964

$284 / night

Fare rows

Standard Interior Stateroom

Cabin grade

Available

from $5,964

$284 / night

per person · incl. taxes & fees

Large/Standard Inside Stateroom

Cabin grade

Available

from $6,024

$286 / night

per person · incl. taxes & fees

Standard Interior Stateroom

Cabin grade

Available

from $6,054

$288 / night

per person · incl. taxes & fees

Standard Interior Stateroom

Cabin grade

Available

from $6,084

$289 / night

per person · incl. taxes & fees

Large/Standard Inside Stateroom

Cabin grade

Available

from $6,114

$291 / night

per person · incl. taxes & fees

Large Interior Stateroom

Cabin grade

Available

from $6,144

$292 / night

per person · incl. taxes & fees

Large/Standard Inside Stateroom

Cabin grade

Available

from $6,174

$294 / night

per person · incl. taxes & fees

Oceanview

from $6,284

$299 / night

Fare rows

Large Ocean view Stateroom (Fully Obstructed View)

Cabin grade

Available

from $6,284

$299 / night

per person · incl. taxes & fees

Large Ocean view Stateroom (Fully Obstructed View)

Cabin grade

Available

from $6,374

$303 / night

per person · incl. taxes & fees

Large Ocean view Stateroom (Partial Sea View)

Cabin grade

Available

from $6,444

$306 / night

per person · incl. taxes & fees

Large Ocean view Stateroom

Cabin grade

Available

from $6,484

$308 / night

per person · incl. taxes & fees

Large Ocean view Stateroom

Cabin grade

Available

from $6,554

$312 / night

per person · incl. taxes & fees

Large Ocean view Stateroom

Cabin grade

Available

from $6,624

$315 / night

per person · incl. taxes & fees

Large Ocean view Stateroom

Cabin grade

Available

from $6,694

$318 / night

per person · incl. taxes & fees

Large Ocean view Stateroom

Cabin grade

Available

from $6,764

$322 / night

per person · incl. taxes & fees

Balcony

from $8,114

$386 / night

Fare rows

Verandah Stateroom

Cabin grade

Available

from $8,114

$386 / night

per person · incl. taxes & fees

Verandah Stateroom

Cabin grade

Available

from $8,264

$393 / night

per person · incl. taxes & fees

Verandah Stateroom

Cabin grade

Available

from $8,384

$399 / night

per person · incl. taxes & fees

Verandah Stateroom

Cabin grade

Available

from $8,504

$404 / night

per person · incl. taxes & fees

Verandah Stateroom

Cabin grade

Available

from $8,624

$410 / night

per person · incl. taxes & fees

Verandah Stateroom

Cabin grade

Available

from $8,744

$416 / night

per person · incl. taxes & fees

Verandah Stateroom

Cabin grade

Available

from $8,864

$422 / night

per person · incl. taxes & fees

Suite

from $10,924

$520 / night

Fare rows

Signature Suite

Cabin grade

Available

from $10,924

$520 / night

per person · incl. taxes & fees

Prices verified Sep 4, 2026

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The journey

21 nights, in order

Trieste

Day 1 Sep 21, 2027

Trieste

If you are looking for elegance and culture, the ideal destination is Trieste.

Explore Trieste

Day by day

The full itinerary

23 scheduled calls
Oosterdam

Your ship

Oosterdam

Oosterdam, a Vista-class ship, recently emerged from dry dock with exciting updates—including completely refreshed suites and new lounge, dining and entertainment venues, such as Music Walk, with Lincoln Center Stage, B.B. King’s Blues Club and Billboard Onboard. Guests can choose from among delectable specialty restaurants, hone culinary skills with EXC Port to Table and thrill to BBC Earth Experiences.

5★ 82,305 GT 1,916 Passengers Built 2003
Oosterdam ship guide Search cruises on Oosterdam

Deck plans

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from $5,964 pp

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