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20-night Mediterranean cruise: Istanbul to Civitavecchia, Rome on Sirena

The Istanbul to Rome is a 20-night Mediterranean cruise aboard Sirena, operated by Oceania Cruises. Departing Istanbul on November 12, 2026 and arriving in Civitavecchia, Rome on December 2, 2026, the voyage visits 21 ports including Bozcaada Island, Turkey, Mykonos, Athens (Piraeus), Greece. CruiseCaptain has fare history for this sailing.

Length
20 nights
Departs
Nov 12, 2026
Returns
Dec 2, 2026
Ports of call
21

Voyage code SIR261112A

Istanbul

20 nights · Mediterranean

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Why this route stands out

A closer look at the journey

Istanbul

A shore excursion on your MSC Mediterranean cruise can be the opportunity to discover İstanbul which stands astride two continents, Europe and Asia. As if its spectacular geographical location were not enough, it can also boast of being the only city to have played capital to consecutive Christian and Islamic empires, a role that has shaped the region’s history for more than 2500 years and bequeathed to İstanbul a staggering wealth of attractions. Most cruise visitors spend all their holiday time in Sultanahmet, home to İstanbul’s main sightseeing attractions: the church of Aya Sofya, the greatest legacy of the Byzantine Empire; the Topkapı Palace, heart of the Ottoman Empire; and the massive Sultanahmet Camii (Blue Mosque). Here also are the ancient Hippodrome, the Museum of Turkish and Islamic Art (housed in the former Palace of İbrahim Paşa), the eerily lit Yerebatan Sarnıcı, a fascinating Byzantine underground cistern, and the Grand Bazaar (Kapalı Çarşı), the largest covered bazaar in the world. The monumental architecture, attractive parks and gardens, street-side cafés, and the benefits of a relatively traffic-free main road combine to make this area pleasant for both sightseeing and staying on an MSC Mediterranean cruise excursion. İstanbul’s Ottoman-era Grand Bazaar gets more than its fair share of souvenir-hungry visitors. The area around it, however, is relatively little explored, which is a shame as it holds some very worthwhile attractions, from the historic Cembirlitaş Hamamı, one of the best Turkish baths in the country, to the city’s very best mosque, the hilltop Süleymaniye Camii. The best single reason to head across to the Asian shore of the city is to experience a Bosphorus cruise. The views from the Bosphorus are superb, with domes and minarets dominating the skyline of the Old City, and skyscrapers the business districts beyond Beyoğlu.

Mykonos

Think of a trip to Greece and you will imagine Mykonos. The port of Mykonos, or perhaps it would be more correct to say of Chora, is located on the west coast of the island. The Cyclades islands in the Aegean are wonderful and the beaches are no less marvellous, with the pleasant distinction of being among the most festive in the archipelago. After docking at the port of Mykonos, enjoy the numerous natural coves, beaches and cliffs of this beautiful island. You can enjoy the clean, azure sea of Paradise Beach, while in the evening let yourself be carried away by the rhythm of this cosmopolitan and youthful island. The harbour district, the Kastro, is known as the 'little Venice'. In its alleys, the shops and restaurants alternate with white houses with blue doors and windows. On a trip to Mykonos, take advantage of the stop to go on shore excursions, stroll through the maze of streets and alleys where you can discover the beauty of the architecture and the design of the city. The small white houses with shutters as blue as the sky, the pigeon houses and the numerous small churches of Mykonos will simply enchant you.

Athens (Piraeus), Greece

A city of legend, civilisation and enduring culture, Athens is a majestic and magical urban sprawl. Extraordinary elegance and grace combine with grit and graft in Greece's capital, where highways encase ruins from antiquity, and gleaming museums and galleries stand beside concrete sprayed with edgy street art. These contrasts enhance and elevate the wonders of this 2,500-year-old city, however, which can count notable contributions to philosophy, drama and democracy, among its global legacy. Piraeus' giant port and naval base welcome you to the edge of the Athens' urban area. From there it's a simple jaunt to the centre. The majestic ancient citadel of the Acropolis dominates an elevated platform and is a constant presence as you explore the city. The wonderful remains of the columned temple of the Parthenon - which date back to the 5th century BC - stand here, representing the pinnacle of classical architecture. The nearby Acropolis Museum adds context to your visit and frames the broad views from its giant glass windows. Or rise up Mount Lycabettus, to be rewarded with perhaps Athens' best panorama of the Acropolis sitting high over the city on its grand stage. See the marble horseshoe of the Old Olympic Stadium, where the first modern Olympics were held in 1896, for more of the city's enduring legacy. Elsewhere, golden beaches and temples stretch out along the coastline, should you wish to explore a little further afield. Coffee is an art form to the Greeks, and it's an unwritten rule that coffee time must never be rushed. So prepare to settle down for a couple of hours and lose yourself in a good chat. Feeling hungry - try traditional souvlaki made with sauces handed from generation to generation.

Price tracking

Today’s fare, in context

Price history

Cheaper than 87%
30 days
Fare details

Fare details

Per person · taxes & fees included
Current fares

No live fare right now.

Tracked range
161 days
Price history by cabin type
CabinCurrentLowestHighest
Inside $5,699 $5,599 on May 1 $5,699 on Mar 25
Oceanview $6,099 $6,099 on Mar 25 $6,099 on Mar 25
Balcony $10,099 $9,199 on Mar 25 $10,099 on Aug 5
Suite $24,899 $12,999 on Apr 26 $24,899 on Jul 28
Cabin grades
16 total
Concierge VerandaBalcony · A1
Concierge VerandaBalcony · A2
Concierge VerandaBalcony · A3
Veranda StateroomBalcony · B1
Veranda StateroomBalcony · B2
Inside StateroomInside · F
Inside StateroomInside · G
Deluxe Ocean View StateroomOceanview · C1
Deluxe Ocean View StateroomOceanview · C2
Ocean View StateroomOceanview · D
Solo Oceanview StateroomOceanview · S
Owner's SuiteSuite · OS
Penthouse SuiteSuite · PH1
Penthouse SuiteSuite · PH2
Penthouse SuiteSuite · PH3
Vista SuiteSuite · VS

○ = last seen (sold out or delisted).

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Current prices

Per person · 2 guests · incl. taxes & fees

Price information is not available.

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The journey

20 nights, in order

Istanbul

Day 1 Nov 12, 2026

Istanbul

A shore excursion on your MSC Mediterranean cruise can be the opportunity to discover İstanbul which stands astride two continents, Europe and Asia.

Explore Istanbul

Day by day

The full itinerary

21 scheduled calls
Sirena

Your ship

Sirena

Elegant sister ship to charming Regatta, Insignia and Nautica, Oceania Cruises’ newest addition, Sirena embodies the most treasured elements of our celebrated fleet, and features a few highlights all her own. With the introduction of two culinary experiences, Sirena offers even more ways to savor The Finest Cuisine at Sea. Tuscan Steak, a new specialty restaurant, serves Italian favorites, succulent steaks and fresh seafood inspired by Toscana and Polo Grill. The Grand Dining Room offers a surprise transformation into The Bistro during lunch, which serves classic French fare as well as regional specialties and lunchtime favorites. Also featuring the beloved restaurant Red Ginger, Sirena invites you to enjoy bold Asian cuisine in a fresh new way.

5★ 30,277 GT 670 Passengers Adults Only
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Deck plans

Deck plan for Deck 3

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