Rome to Valletta

The Rome to Valletta is a 10-night Mediterranean cruise aboard Sirena, operated by Oceania Cruises. Departing Civitavecchia, Rome on September 10, 2026, the voyage visits 10 ports. Fares start from $3,399 per person.

Length: 10 nights
Departs: Sep 10, 2026
Returns: Sep 20, 2026
Ports of call: 10
Days at sea: 1

from $3,399

$339 / night per person, incl. taxes & fees

Book with CruiseDirect Book direct with Oceania Cruises

We may earn a commission

from $3,399 pp

via CruiseDirect

Book

Book direct with Oceania Cruises we may earn a commission

Itinerary

Day 1 Sep 10, 2026 Civitavecchia, Rome Departs 17:00 All roads lead to Rome, and with good reason - this city is one of the world’s most thrilling, offering unmatched history along every street. An evocative, inspiring and utterly artistic capital of unrivalled cultural impact, Rome is a city of back-to-back landmarks, which will take you on an exhilarating journey through the ages. This may be one of the world’s oldest cities, but it’s well and truly lived in. The ruins are punctuated with murmuring cafes, and the outdoor seating of restaurants sprawls out across piazzas, enticing you to sample tangles of creamy pasta and crispy pizzas. Rome’s incredible Roman Forum is littered with the ruins of its ancient administrations, which have stood firm for 2,000 years, since the times when the area was the centre of the Western world. Few sites are more simultaneously beautiful and haunting than that of the storied Colosseum, which looms deep into Rome’s rich blue sky. Take a tour to learn details of the grisly goings-on within. The best way to experience Rome is to wander its streets, gelato in hand. There is a lot to see here - whether it’s the domed spectacle of the Pantheon, or the elaborate flowing waters and artistry of the Trevi Fountain. Vatican City is an astonishing, colossal display of Catholic grandeur, while the Spanish Steps – crowned by the Trinità dei Monti church – offer a beautiful spot to gather and soak up the lively atmosphere of this humming city. With so much on the to-do list, you’ll relish the breaks you take, enjoying simple pleasures like a strong espresso, or fresh pasta with tomato sauce and ripped basil. Civitavecchia, Rome port guide Search cruises visiting Civitavecchia, Rome

Day 2 Sep 11, 2026 Livorno 08:00 – 23:00 15.0 hrs ashore There are few more elegant places to salute the sunset than Terrazza Mascagni, Livorno’s refined chessboard piazza. A historic port, and a beachy gateway to Tuscany, Livorno welcomes you ashore to explore this enchanted Italian region's sun-soaked beauty, rich flavours and world-renowned fine art. Stay in Livorno to explore 'Piccolo Venezia', or ‘Little Venice’ - a quarter of the town that's laced with canals, little marble bridges and plenty of tempting eateries. View less With its bustling market, fortresses and iconic waterfront, there’s plenty to keep you busy here, but most will be tempted to venture inland to explore more of Tuscany’s many charms and artistic wonders. Test your nose, as you breathe in the subtleties of Tuscany’s vineyard-draped scenery, and visit wineries showcasing the best of the renowned flavours of the Bolgheri wine-growing area. Or head out to Prato, where you’ll find tightly-woven textile history. Pisa’s showpiece tower is within reach, as is Florence’s city of immense and imaginative renaissance beauty. Admire the delicate carving of Michelangelo's masterpiece, the David statue, and note the provocative stance as he casts a dismissive glance towards Rome. Stand before the city’s majestic black and white cathedral - the Cathedral of Santa Maria del Fiore - with its colossal brick dome. The view down over Florence's river and grand dome from Piazzale Michelangelo, meanwhile, is one of Italy's finest. However you choose to spend your time in Tuscany, you’ll discover an artistic region, filled with beauty designed to appeal to every sense. Livorno port guide Search cruises visiting Livorno

Livorno photo — Day 2 Sep 11, 2026 Livorno 08:00 – 23:00 15.0 hrs ashore There are few more elegant places to salute the sunset than Terrazza Mascagni, Livorno’s refined chessboard piazza. A historic port, and a beachy gateway to Tuscany, Livorno welcomes you ashore to explore this enchanted Italian region's sun-soaked beauty, rich flavours and world-renowned fine art. Stay in Livorno to explore 'Piccolo Venezia', or ‘Little Venice’ - a quarter of the town that's laced with canals, little marble bridges and plenty of tempting eateries. View less With its bustling market, fortresses and iconic waterfront, there’s plenty to keep you busy here, but most will be tempted to venture inland to explore more of Tuscany’s many charms and artistic wonders. Test your nose, as you breathe in the subtleties of Tuscany’s vineyard-draped scenery, and visit wineries showcasing the best of the renowned flavours of the Bolgheri wine-growing area. Or head out to Prato, where you’ll find tightly-woven textile history. Pisa’s showpiece tower is within reach, as is Florence’s city of immense and imaginative renaissance beauty. Admire the delicate carving of Michelangelo's masterpiece, the David statue, and note the provocative stance as he casts a dismissive glance towards Rome. Stand before the city’s majestic black and white cathedral - the Cathedral of Santa Maria del Fiore - with its colossal brick dome. The view down over Florence's river and grand dome from Piazzale Michelangelo, meanwhile, is one of Italy's finest. However you choose to spend your time in Tuscany, you’ll discover an artistic region, filled with beauty designed to appeal to every sense. Livorno port guide Search cruises visiting Livorno

Day 5 Sep 14, 2026 Marseille, France 08:00 – 18:00 10.0 hrs ashore Marseille is the second largest city in France after Paris. It is also one of the oldest continuously inhabited cities in the Mediterranean. Cave paintings in the nearby Calanques are estimated to be 30,000 years old, and remains of brick habitations date from 6,000 BCE. The more recent history begins with a Hellenic port in about 600 BCE, some remains of which are on view at the city’s History Museum. It has been one of the world’s major seaports almost from its founding, and served as the main European terminus of the French colonial empire in Africa and the Far East. It is located in the Provence-Alpes-Cote d’Azur region and is the capital of the Bouches-du-Rhone department. On an island in the expansive bay of Marseille stands the prison of Chateau d’If made famous by the Alexandre Dumas novel “The Count of Monte Cristo.” The Vieux-Port with its atmospheric buildings and wharves is the area where visitors can search for the perfect example of the local specialty bouillabaisse, a rich fish stew containing at least three, and often more varieties of local fishes. Marseille’s newly renovated port at the venerable Joliette Docks is situated very close to the striking Cathédrale de la Major and the fascinating collections at the Museum of African, Oceanic and American Indian Arts. Marseille, France port guide Search cruises visiting Marseille, France

Marseille, France photo — Day 5 Sep 14, 2026 Marseille, France 08:00 – 18:00 10.0 hrs ashore Marseille is the second largest city in France after Paris. It is also one of the oldest continuously inhabited cities in the Mediterranean. Cave paintings in the nearby Calanques are estimated to be 30,000 years old, and remains of brick habitations date from 6,000 BCE. The more recent history begins with a Hellenic port in about 600 BCE, some remains of which are on view at the city’s History Museum. It has been one of the world’s major seaports almost from its founding, and served as the main European terminus of the French colonial empire in Africa and the Far East. It is located in the Provence-Alpes-Cote d’Azur region and is the capital of the Bouches-du-Rhone department. On an island in the expansive bay of Marseille stands the prison of Chateau d’If made famous by the Alexandre Dumas novel “The Count of Monte Cristo.” The Vieux-Port with its atmospheric buildings and wharves is the area where visitors can search for the perfect example of the local specialty bouillabaisse, a rich fish stew containing at least three, and often more varieties of local fishes. Marseille’s newly renovated port at the venerable Joliette Docks is situated very close to the striking Cathédrale de la Major and the fascinating collections at the Museum of African, Oceanic and American Indian Arts. Marseille, France port guide Search cruises visiting Marseille, France

Day 6 Sep 15, 2026 Barcelona 08:00 – 20:00 12.0 hrs ashore On the northeast coast of Spain, overlooking the Mediterranean, Barcelona is a vibrant port city, packed with centuries of iconic art and architecture—Gaudí and Picasso both called it home—and lined with sunny white-sand beaches. Explore the Catalan capital's tourist attractions and historic neighborhoods, Modernisme and world-renowned art museums, galleries and local crafts shops—some of which are centuries old and stock traditional Catalan wares. After you see the sights, there are lively tapas bars around every corner where you can stop for a drink, a café amb llet (Catalan for espresso with steamed milk) or a snack, no matter the hour. Green spaces for picnics, long walks and respite from the hustle and bustle are scattered throughout Barcelona's attractions: There's Gaudí's mosaic-decorated park, a neoclassical maze at the Laberint d'Horta, as well as plenty of high places (mountains, monuments and edifices) where sightseeing visitors can take in the view. A short trip from Barcelona by car or train, luxury outlets, cava wineries, a mountaintop abbey and the sandy beaches of the Mediterranean coast await. Barcelona port guide Search cruises visiting Barcelona

Barcelona photo — Day 6 Sep 15, 2026 Barcelona 08:00 – 20:00 12.0 hrs ashore On the northeast coast of Spain, overlooking the Mediterranean, Barcelona is a vibrant port city, packed with centuries of iconic art and architecture—Gaudí and Picasso both called it home—and lined with sunny white-sand beaches. Explore the Catalan capital's tourist attractions and historic neighborhoods, Modernisme and world-renowned art museums, galleries and local crafts shops—some of which are centuries old and stock traditional Catalan wares. After you see the sights, there are lively tapas bars around every corner where you can stop for a drink, a café amb llet (Catalan for espresso with steamed milk) or a snack, no matter the hour. Green spaces for picnics, long walks and respite from the hustle and bustle are scattered throughout Barcelona's attractions: There's Gaudí's mosaic-decorated park, a neoclassical maze at the Laberint d'Horta, as well as plenty of high places (mountains, monuments and edifices) where sightseeing visitors can take in the view. A short trip from Barcelona by car or train, luxury outlets, cava wineries, a mountaintop abbey and the sandy beaches of the Mediterranean coast await. Barcelona port guide Search cruises visiting Barcelona

Day 7 Sep 16, 2026 Valencia 08:00 – 17:00 9.0 hrs ashore Valencia is Spain's third largest city and capital of the region. It was originally founded by the Romans on the banks of the river Turia in 138 BC. In 711 AD the Moors arrived and converted the area into a rich agricultural and industrial center, establishing ceramics, paper, silk and leather industries. Muslim rule was briefly interrupted in 1094 by the legendary Castillian knight, El Cid. Valencia boomed in the 15th and 16th centuries, becoming one of the strongest Mediterranean trading centers. Valencia is a vibrant, friendly and chaotic city that boasts an outstanding fine arts museum and one of the most exciting nightlife scenes in Spain. The city center is about 3 miles inland from the coast. Plaza del Ayuntamiento marks the center of Valencia. Surrounded by flower stalls, it is also home to the town hall and the main post office. The cathedral was begun in the 13th century and finished in 1482. It has many architectural styles, including Gothic, Baroque and Romanesque. The octagonal bell-tower, called Miguelete, is one of the city's landmarks. The small cathedral museum boasts a tabernacle made from 550 pounds of gold, silver, platinum, emeralds and sapphires. It also purports to be the home of the Holy Grail, the cup used by Christ at the Last Supper. West of the cathedral is the oldest part of the city, known as El Carme. Situated across the river in the Jardines del Real is the Museo de Bellas Artes, the Fine Arts Museum. Works include those by El Greco, Goya and Velázquez. Valencia port guide Search cruises visiting Valencia

Valencia photo — Day 7 Sep 16, 2026 Valencia 08:00 – 17:00 9.0 hrs ashore Valencia is Spain's third largest city and capital of the region. It was originally founded by the Romans on the banks of the river Turia in 138 BC. In 711 AD the Moors arrived and converted the area into a rich agricultural and industrial center, establishing ceramics, paper, silk and leather industries. Muslim rule was briefly interrupted in 1094 by the legendary Castillian knight, El Cid. Valencia boomed in the 15th and 16th centuries, becoming one of the strongest Mediterranean trading centers. Valencia is a vibrant, friendly and chaotic city that boasts an outstanding fine arts museum and one of the most exciting nightlife scenes in Spain. The city center is about 3 miles inland from the coast. Plaza del Ayuntamiento marks the center of Valencia. Surrounded by flower stalls, it is also home to the town hall and the main post office. The cathedral was begun in the 13th century and finished in 1482. It has many architectural styles, including Gothic, Baroque and Romanesque. The octagonal bell-tower, called Miguelete, is one of the city's landmarks. The small cathedral museum boasts a tabernacle made from 550 pounds of gold, silver, platinum, emeralds and sapphires. It also purports to be the home of the Holy Grail, the cup used by Christ at the Last Supper. West of the cathedral is the oldest part of the city, known as El Carme. Situated across the river in the Jardines del Real is the Museo de Bellas Artes, the Fine Arts Museum. Works include those by El Greco, Goya and Velázquez. Valencia port guide Search cruises visiting Valencia

Day 8 Sep 17, 2026 Alicante 08:00 – 18:00 10.0 hrs ashore Fresh sea breezes, mountain backdrops and vibrant locals have made this magical city a must-see for both international tourists and residents of Spain alike. It's easy to slip into the local rhythm. Spend your day exploring everything from the Old Town and Santa Bárbara Castle to the trendiest of Spanish stores. Promenade down the marble Explanada de España, an iconic and bustling boulevard dotted with palm trees. Enjoy a proper Spanish lunch that spans several courses and hours, prepared by some of the best chefs in the country. Take advantage of the proximity to the sea to dine on the freshest seafood, or try one of Alicante's many traditional rice dishes. And don’t forget to sample the outstanding regional wines, which are also very tasty souvenirs. Even just a day here will open your eyes to the natural beauty and subtle charms that make proud and elegant Alicante a gem of the Costa Blanca. Alicante port guide Search cruises visiting Alicante

Alicante photo — Day 8 Sep 17, 2026 Alicante 08:00 – 18:00 10.0 hrs ashore Fresh sea breezes, mountain backdrops and vibrant locals have made this magical city a must-see for both international tourists and residents of Spain alike. It's easy to slip into the local rhythm. Spend your day exploring everything from the Old Town and Santa Bárbara Castle to the trendiest of Spanish stores. Promenade down the marble Explanada de España, an iconic and bustling boulevard dotted with palm trees. Enjoy a proper Spanish lunch that spans several courses and hours, prepared by some of the best chefs in the country. Take advantage of the proximity to the sea to dine on the freshest seafood, or try one of Alicante's many traditional rice dishes. And don’t forget to sample the outstanding regional wines, which are also very tasty souvenirs. Even just a day here will open your eyes to the natural beauty and subtle charms that make proud and elegant Alicante a gem of the Costa Blanca. Alicante port guide Search cruises visiting Alicante

Day 9 Sep 18, 2026 Palma de Mallorca 07:00 – 15:00 8.0 hrs ashore The Balearics are comprised of 16 islands; the three principal ones are Mallorca, Ibiza and Minorca. Carthaginians, Romans, Vandals and Arabs have invaded these islands over the centuries. Ruins show evidence of the prehistoric Talayot civilization, a megalithic culture that flourished here between 1500 BC and the Roman conquest. Today the islands are besieged by invaders of a different sort - hordes of tourists. Lying 60 miles (97 km) off the Spanish mainland, the islands' lush and rugged landscape combined with an extremely mild, sunny climate proves irresistible, especially to northern Europeans. As a result, the Balearics boast cosmopolitan resorts with lively nightlife and plenty of sports activities. Mallorca (also spelled Majorca) is the largest of the islands, with an area of more than 1,400 square miles (3626 sq.km). The scenery is magnificent, with cliffs along indented shorelines jutting out of the sea and mountain ranges sheltering the plains from harsh sea breezes. The fertile plain in the centre is covered with almond and fig trees plus olive groves with some trees more than 1,000 years old. Tall pines, junipers and oaks line the mountain slopes. Palma de Mallorca is the capital of the archipelago. A cosmopolitan city with sophisticated shops and restaurants, it also offers buildings of spectacular Moorish and Gothic architecture. In the western part of Mallorca, nestled into the mountains, lies the village of Valldemosa. It is known for its Carthusian Monastery where Frédéric Chopin and George Sand spent the winter of 1838-39. Palma de Mallorca port guide Search cruises visiting Palma de Mallorca

Palma de Mallorca photo — Day 9 Sep 18, 2026 Palma de Mallorca 07:00 – 15:00 8.0 hrs ashore The Balearics are comprised of 16 islands; the three principal ones are Mallorca, Ibiza and Minorca. Carthaginians, Romans, Vandals and Arabs have invaded these islands over the centuries. Ruins show evidence of the prehistoric Talayot civilization, a megalithic culture that flourished here between 1500 BC and the Roman conquest. Today the islands are besieged by invaders of a different sort - hordes of tourists. Lying 60 miles (97 km) off the Spanish mainland, the islands' lush and rugged landscape combined with an extremely mild, sunny climate proves irresistible, especially to northern Europeans. As a result, the Balearics boast cosmopolitan resorts with lively nightlife and plenty of sports activities. Mallorca (also spelled Majorca) is the largest of the islands, with an area of more than 1,400 square miles (3626 sq.km). The scenery is magnificent, with cliffs along indented shorelines jutting out of the sea and mountain ranges sheltering the plains from harsh sea breezes. The fertile plain in the centre is covered with almond and fig trees plus olive groves with some trees more than 1,000 years old. Tall pines, junipers and oaks line the mountain slopes. Palma de Mallorca is the capital of the archipelago. A cosmopolitan city with sophisticated shops and restaurants, it also offers buildings of spectacular Moorish and Gothic architecture. In the western part of Mallorca, nestled into the mountains, lies the village of Valldemosa. It is known for its Carthusian Monastery where Frédéric Chopin and George Sand spent the winter of 1838-39. Palma de Mallorca port guide Search cruises visiting Palma de Mallorca

Day 11 Sep 20, 2026 Malta Arrives 08:00 The UNESCO-protected port of Valletta, the capital of the island of Malta, is one of the must-see stops for every Mediterranean cruise of merit. You can admire this port, constructed in the second half of the 16th century by the Frenchman Jean de la Valette and moulded by the religious and military Order of Saint John of Jerusalem, from your MSC ship even before disembarking. The over 300 monuments rising in little more than half a square kilometre make this a place with one of the greatest density of historical attractions to visit during a cruise, not mentioning other attractions such as its beaches, seaside locales and restaurants. An excursion to the island can start right from its capital, Valletta, which enchants the cruise-goer with its famous Maltese balconies, which decorate the facades of houses in its old quarter. Surrounded by a multitude of churches, which the islanders assure are as many as the days of the year, the St. John’s Co-Cathedral is one of Malta’s biggest tourist attractions. The National Museum of Archaeology, on the other hand, hosts prehistoric artefacts found on the island. By the Grand Harbour, one can visit the underground passages of Auberge de Castille and the beautiful Baracca Gardens, which overlook the harbour; at night, when the city gates would close, its porticoes served as shelter for travellers. To get a taste of the life of Malta’s ancient nobility, visit Casa Rocca Piccola. A 16th century Palazzo now the residence of the 9th Marquis De Piro, it has period furnishings and has a bomb shelter built for protection against bombings during the Second World War. The set of the film Popeye can still be seen from Malta’s largest beach, as well as the Sanctuary of Our Lady of Mellieha with a fresco of the Blessed Virgin Mary with Christ; according to tradition, Saint Luke, who was shipwrecked on the island with Saint Paul, is the author of this Byzantine-style fresco. Malta port guide Search cruises visiting Malta

Malta photo — Day 11 Sep 20, 2026 Malta Arrives 08:00 The UNESCO-protected port of Valletta, the capital of the island of Malta, is one of the must-see stops for every Mediterranean cruise of merit. You can admire this port, constructed in the second half of the 16th century by the Frenchman Jean de la Valette and moulded by the religious and military Order of Saint John of Jerusalem, from your MSC ship even before disembarking. The over 300 monuments rising in little more than half a square kilometre make this a place with one of the greatest density of historical attractions to visit during a cruise, not mentioning other attractions such as its beaches, seaside locales and restaurants. An excursion to the island can start right from its capital, Valletta, which enchants the cruise-goer with its famous Maltese balconies, which decorate the facades of houses in its old quarter. Surrounded by a multitude of churches, which the islanders assure are as many as the days of the year, the St. John’s Co-Cathedral is one of Malta’s biggest tourist attractions. The National Museum of Archaeology, on the other hand, hosts prehistoric artefacts found on the island. By the Grand Harbour, one can visit the underground passages of Auberge de Castille and the beautiful Baracca Gardens, which overlook the harbour; at night, when the city gates would close, its porticoes served as shelter for travellers. To get a taste of the life of Malta’s ancient nobility, visit Casa Rocca Piccola. A 16th century Palazzo now the residence of the 9th Marquis De Piro, it has period furnishings and has a bomb shelter built for protection against bombings during the Second World War. The set of the film Popeye can still be seen from Malta’s largest beach, as well as the Sanctuary of Our Lady of Mellieha with a fresco of the Blessed Virgin Mary with Christ; according to tradition, Saint Luke, who was shipwrecked on the island with Saint Paul, is the author of this Byzantine-style fresco. Malta port guide Search cruises visiting Malta

Pricing

Lowest fare we've tracked over the observed 99-day span: $2,560 · range $2,560–$2,890

Lower than 72% of peers This longer-duration sailing's from-price per night is lower than 72% of comparable sailings.

same cruise line, destination, and duration · from-price per night · as of Jul 1, 2026 · Broader cohort: same cruise line and duration, compared by from-price per night.

Current prices

Per person · 2 guests · incl. taxes & fees

Inside

from $3,399

$339 / night

Fare rows

Inside Stateroom

Cabin grade

Available

from $3,399

$339 / night

per person · incl. taxes

Inside Stateroom

Cabin grade

Available

from $3,449

$344 / night

per person · incl. taxes

Oceanview

from $3,899

$389 / night

Fare rows

Ocean View Stateroom

Cabin grade

Available

from $3,899

$389 / night

per person · incl. taxes

Deluxe Ocean View Stateroom

Cabin grade

Available

from $4,149

$414 / night

per person · incl. taxes

Deluxe Ocean View Stateroom

Cabin grade

Available

from $4,499

$449 / night

per person · incl. taxes

Solo Oceanview Stateroom

Cabin grade

Available

from $6,799

$679 / night

per person · incl. taxes

Balcony

from $5,549

$554 / night

Fare rows

Veranda Stateroom

Cabin grade

Available

from $5,549

$554 / night

per person · incl. taxes

Concierge Veranda

Cabin grade

Available

from $5,649

$564 / night

per person · incl. taxes

Concierge Veranda

Cabin grade

Available

from $5,749

$574 / night

per person · incl. taxes

Concierge Veranda

Cabin grade

Available

from $5,999

$599 / night

per person · incl. taxes

Suite

from $11,999

$1,199 / night

Fare rows

Owner's Suite

Cabin grade

Available

from $11,999

$1,199 / night

per person · incl. taxes

Prices verified Jul 1, 2026

Prices come from third-party data feeds via Oceania Cruises and may differ from the cruise line's current fare. Confirm the final price before booking. How our pricing works

Show all 16 cabin grades

Cabin grades and pricing
Name	Supplier code	Type
Concierge Veranda	A1	Balcony
Concierge Veranda	A2	Balcony
Concierge Veranda	A3	Balcony
Veranda Stateroom	B1	Balcony
Veranda Stateroom	B2	Balcony
Inside Stateroom	F	Inside
Inside Stateroom	G	Inside
Deluxe Ocean View Stateroom	C1	Oceanview
Deluxe Ocean View Stateroom	C2	Oceanview
Ocean View Stateroom	D	Oceanview
Solo Oceanview Stateroom	S	Oceanview
Owner's Suite	OS	Suite
Penthouse Suite	PH1	Suite
Penthouse Suite	PH2	Suite
Penthouse Suite	PH3	Suite
Vista Suite	VS	Suite