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Miami, Florida

16 nights · Central America

16-night Central America cruise: Miami, Florida to Los Angeles, CA on Brilliant Lady

The Panama Canal: Miami to Los Angeles is a 16-night Central America cruise aboard Brilliant Lady, operated by Virgin Voyages. Departing Miami, Florida on February 21, 2028 and arriving in Los Angeles, CA on March 8, 2028, the voyage visits 8 ports including Cartagena, Colombia, Colon, Panama, Panama Canal. Fares start from $2,065 per person.

Length
16 nights
Departs
Feb 21, 2028
Returns
Mar 8, 2028
Ports of call
8
Days at sea
9

Voyage code BR28022116NMLAX

from $2,065 pp

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Why this route stands out

A closer look at the journey

Fixed editorial images from the places on this itinerary. They stay stable each time you return to this sailing.

Miami, Florida

Miami is called the gateway to the Americas, and it’s indeed a very glamourous global city to explore at the start or end of an MSC Caribbean and Antilles cruise. Home to many cultures, the city of Miami sizzles with flavours from the Americas, beginning with Cuba and the Little Havana neighbourhood - one of the most historically significant places, while Wynwood is famous for its wall art and Puerto Rican history. Across Biscayne Bay lies the city of Miami Beach, home to the world-famous South Beach. An MSC-arranged guided private tour opens up a world of possibilities for you: enjoy the beach, take in the city’s Art Deco architecture and enjoy a drink on legendary Ocean Drive, where you can people watch, and perhaps spot a celebrity. If time permits, take a stroll on artsy Lincoln Road packed with street side cafes and shops. Facing the MSC Cruises port in downtown Miami is Bayside Marketplace - a lively commercial centre that is a staging area for boat tours of Miami. Seeing the city from the water, with its impressive skyline and waterfront mansions, is an experience in itself. The downtown area also boasts the dazzling Performing Arts Centre, the Museum of Science, the Pérez Art Museum Miami (known as the PAMM), scenic Bayfront Park and the arena where the 3-time NBA champion Miami Heat basketball team plays. Miami is renowned for its shopping. Hop on a tour to see the major city sights followed by retail therapy at one of Miami's largest and newest shopping malls: Dolphin Mall. With more than 240 retail outlets, you’re bound to need a bit of room in your luggage for your purchases. Luckily, there are several luggage stores at the mall to fill that need. Head west past the city into untamed wilderness on an MSC excursion into the Everglades. At this national park where water is the central feature, unlike any other in North America, nature enthusiasts can hop on an airboat tour through the swampland and waterways to spot alligators and a variety of birds.

Cartagena, Colombia

Cobbled streets, balconies overflowing with blooming bougainvillea and pastel-coloured buildings lining elegant plazas make Cartagena in Colombia one of the Caribbean's most photogenic cities, and a memorable stop on an MSC Caribbean and Antilles cruise. Founded in 1533, this Spanish colonial city, a UNESCO World Heritage Site, is steeped in history. Its location made it a popular target for plunderers and English pirates, and arguably features the most impressive collection of forts in the Caribbean. Today the city is eager to share its treasures with modern visitors. Magnificent colonial structures such as the 16th-century Santa Catalina Cathedral, with its striking stuccoes and dome tower, and the three-arch clock gate, the Torre del Reloj, are just two of the many landmarks of this enchanting city dotted with many squares and sidewalk cafés. A wonderful photo stop on our Cartagena City MSC excursion is the San Felipe de Barajas fortress, a marvel of colonial Spanish military engineering. Its construction began in 1536. Slaves la-boured for more than 120 years to erect this fortress - built on high ground with dominating ap-proaches to the city by land and sea to fend off pirates - and its network of tunnels. On yet another MSC excursion, enrich your palate as you learn about the rich aromas and flavours of Colombian coffee. Introduced by the Jesuits in 1723, coffee quickly became a key crop in Colombia, which is now one of the top producers of Arabica coffee in the world. Colombia is also the world’s top producer of emeralds. If jewellery and gems fascinate you, learn all about these green precious stones and make your own emerald-studded jewellery in sterling silver during a hands-on MSC excursion that guides you step-by-step. And you don’t need to go far to explore nature. An MSC excursion takes you by canoe through mangrove tunnels to Ciénaga de la Virgen, where you can witness a diversity of birds from king-fishers and white herons to pelicans and pink-feathered roseate spoonbills.

Panama Canal

Panama is synonymous with the Panama Canal. While Panama connects Central America to South America, the Panama Canal, which opened in 1914, connects the Caribbean Sea with the Pacific Ocean. The channel reduces shipping time and currently connects 160 countries and 1,700 ports around the world. Hailed as an engineering marvel, the artificial waterway with its elaborate lock system is one of the greatest achievements of the 20th century. Arriving on an MSC Caribbean and Antilles cruise into Colón, Panama’s gateway city, you’ll encounter the irresistible juxtaposition of the ancient and modern, the artificial and natural, as enormous computerized container ships transiting the canal slice through primeval rainforests teeming with fluorescent frogs and elusive wild cats. Book an MSC excursion to hop on a ferry that will take you along the length of the Panama Canal, through lakes and locks and past the Centennial and Americas bridges. Finally, you will arrive at Pacific port at the entrance to the Panama Canal, and then enjoy a 90-minute bus ride back to your ship.

Price tracking

Today’s fare, in context

Price history

90 days
Fare details

Fare details

Per person · taxes & fees included
Current fares
Verified 6 hours ago
Inside
$2,065
Oceanview
$2,544
Balcony
$3,025
Suite
$9,280
Tracked range
156 days
Price history by cabin type
CabinCurrentLowestHighest
Inside $2,065 $1,905 on Mar 26 $2,065 on Apr 1
Oceanview $2,544 $2,385 on Mar 26 $2,544 on Apr 1
Balcony $3,025 $2,865 on Mar 26 $3,185 on May 23
Suite $9,280 $9,180 on May 2 $9,280 on Mar 26
Cabin grades
27 total
Central Sea TerraceBalcony · TC
The Sea TerraceBalcony · TR
Sea Terrace: (Slightly) Smaller BalconyBalcony · TS
XL Sea TerraceBalcony · TX
Ltd View Sea Terrace Lock It In RateBalcony · TZ
Solo InsiderInside · I1
Social InsiderInside · I4
The InsiderInside · IN
Insider Lock It In RateInside · IZ
LTD View Sea TerraceOceanview · TL
Solo Sea ViewOceanview · V1
The Sea ViewOceanview · VW
Seaview Lock It In RateOceanview · VZ
Mega RockStar Lock It In RateSuite · MZ
RockStar Lock It In RateSuite · RZ
Sweet Aft Suite – Biggest TerraceSuite · SAB
Sweet Aft Suite – Even Bigger TerraceSuite · SAE
Sweet Aft Suite – Pretty Big TerraceSuite · SAP
Brilliant SuiteSuite · SB
Cheeky Corner Suite – Biggest TerraceSuite · SCB
Cheeky Corner Suite – Even Bigger TerraceSuite · SCE
Cheeky Corner Suite – Pretty Big TerraceSuite · SCP
Fab SuiteSuite · SF
Gorgeous SuiteSuite · SG
Massive SuiteSuite · SM
Posh SuiteSuite · SP
Seriously SuiteSuite · SS

○ = last seen (sold out or delisted). · Verified 6 hours ago.

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Current prices

Per person · 2 guests · incl. taxes & fees

Inside

from $2,065

$129 / night

Fare rows

Insider Lock It In Rate

Cabin grade

Available

from $2,065

$129 / night

per person · incl. taxes & fees

The Insider

Cabin grade

Available

from $2,321

$145 / night

per person · incl. taxes & fees

Oceanview

from $2,544

$159 / night

Fare rows

Seaview Lock It In Rate

Cabin grade

Available

from $2,544

$159 / night

per person · incl. taxes & fees

The Sea View

Cabin grade

Available

from $3,120

$195 / night

per person · incl. taxes & fees

Balcony

from $3,025

$189 / night

Fare rows

Ltd View Sea Terrace Lock It In Rate

Cabin grade

Available

from $3,025

$189 / night

per person · incl. taxes & fees

Sea Terrace: (Slightly) Smaller Balcony

Cabin grade

Available

from $3,120

$195 / night

per person · incl. taxes & fees

The Sea Terrace

Cabin grade

Available

from $3,521

$220 / night

per person · incl. taxes & fees

Central Sea Terrace

Cabin grade

Available

from $3,760

$235 / night

per person · incl. taxes & fees

XL Sea Terrace

Cabin grade

Available

from $4,160

$260 / night

per person · incl. taxes & fees

Suite

from $9,280

$580 / night

Fare rows

Seriously Suite

Cabin grade

Available

from $9,280

$580 / night

per person · incl. taxes & fees

Brilliant Suite

Cabin grade

Available

from $10,800

$675 / night

per person · incl. taxes & fees

Sweet Aft Suite – Pretty Big Terrace

Cabin grade

Available

from $11,200

$700 / night

per person · incl. taxes & fees

Sweet Aft Suite – Even Bigger Terrace

Cabin grade

Available

from $11,280

$705 / night

per person · incl. taxes & fees

Sweet Aft Suite – Biggest Terrace

Cabin grade

Available

from $11,360

$710 / night

per person · incl. taxes & fees

Cheeky Corner Suite – Pretty Big Terrace

Cabin grade

Available

from $11,760

$735 / night

per person · incl. taxes & fees

Cheeky Corner Suite – Even Bigger Terrace

Cabin grade

Available

from $11,840

$740 / night

per person · incl. taxes & fees

Cheeky Corner Suite – Biggest Terrace

Cabin grade

Available

from $11,920

$745 / night

per person · incl. taxes & fees

Gorgeous Suite

Cabin grade

Available

from $15,200

$950 / night

per person · incl. taxes & fees

Fab Suite

Cabin grade

Available

from $21,600

$1,350 / night

per person · incl. taxes & fees

Prices verified Aug 28, 2026

Prices come from third-party data feeds via Virgin Voyages and may differ from the cruise line's current fare. Confirm the final price before booking. How our pricing works

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The journey

16 nights, in order

Follow the entire sailing from its first day to its last, with the route and schedule in one view.

Miami, Florida

Day 1 Feb 21, 2028

Miami, Florida

Miami is called the gateway to the Americas, and it’s indeed a very glamourous global city to explore at the start or end of an MSC Caribbean and Antilles cruise.

Explore Miami, Florida

Day by day

The full itinerary

17 scheduled calls
Brilliant Lady

Your ship

Brilliant Lady

Rocking a name that balances the duality of the iridescent glow of the seven seas with the fierce intelligence of women across the world, Brilliant Lady, our fourth ship in the fleet, is splashing onto the scene with bright and vivid intention — ready to take you across the world.

5★ 110,000 GT 2,820 Passengers Built 2022 Adults Only
Brilliant Lady ship guide Search cruises on Brilliant Lady

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Advanced options Cabins & price targets

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from $2,065 pp

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