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San Juan, Puerto Rico

5 nights · Caribbean

5-night Caribbean cruise: San Juan, Puerto Rico to Cartagena, Colombia on Crystal Serenity

The San Juan to Cartagena is a 5-night Caribbean cruise aboard Crystal Serenity, operated by Crystal Cruises. Departing San Juan, Puerto Rico on November 27, 2026 and arriving in Cartagena, Colombia on December 2, 2026, the voyage visits 4 ports including Jost Van Dyke, Oranjestad, Aruba. Fares start from $3,000 per person.

Length
5 nights
Departs
Nov 27, 2026
Returns
Dec 2, 2026
Ports of call
4
Days at sea
1

Voyage code CSE-S05-261127

from $3,000 pp

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Why this route stands out

A closer look at the journey

Fixed editorial images from the places on this itinerary. They stay stable each time you return to this sailing.

San Juan, Puerto Rico

Blessed with some of the oldest buildings in the Western Hemisphere, San Juan, Puerto Rico’s cap-ital, is romantically charming with its bright pastel Spanish colonial facades, wrought-iron balconies abloom with flowers, narrow cobblestone streets and beloved park squares. Once you arrive on an MSC Caribbean and Antilles cruise at the port, explore Old San Juan (Viejo San Juan), a UNESCO World Heritage district, widely renowned for the fortresses of Castillo San Felipe del Morro and the Castillo San Cristóbal. The old town occupies the headland of a 2.5-mile-long island (connected by bridge to the mainland) that shelters San Juan Bay, for centuries a key port in the New World. It was originally known as Puerto Rico, or “rich port,” because its location made it the perfect stop for shipping. Several MSC excursions offer walking tours that let you soak up amazing views of San Juan, while making cultural discoveries of a lifetime. Wander through the old town along the Paseo de la Princesa, San Juan’s oldest tree-lined avenue; head up its southern city wall, La Muralla, which until the late 19th century encircled all of Old San Juan with sandstone; and tour the 16th-century fortress of El Morro, with its six different lines of defence. Take a coffee-tasting walking tour to explore Puerto Rico’s rich coffee culture, and learn how the island’s rich volcanic soil and climate have contributed to the rise of coffee as one of its main crops. Taste a delicious cup of freshly brewed Puerto Rican café con leche, learn about the island's historical ties with the caffeine-rich beverage, and explore how coffee and the church are connected on this MSC excursion through the streets of Old San Juan. Or savour San Juan’s culinary delights, in a Martha Stewart excursion curated exclusively for MSC that will have you tasting local cuisine and drinks at five destinations along the route through the fortified colonial city. From Puerto Rican fritters at historic El Convento Hotel, to chocolate tasting at a fourth-generation chocolatier, you won’t want to miss this tour, which ends at La Casita de Rones for a rum lesson and a piña colada, the national drink of Puerto Rico. With more than 80% of the world's rum coming from Puerto Rico, delve deeper into the spirit on an MSC excursion to Casa Bacardí in the town of Cataño. Discover the story behind Bacardí’s legendary cocktails, sniff the products on display and learn about the rum-making process including wood barrelling, ageing and finishing. For the grand finale, enjoy a fascinating mixology show. Nature lovers will not want to miss a visit to El Yunque, the only tropical rainforest in the U.S. territory and one of Puerto Rico's finest spots of natural beauty. Marvel at its small horsetail waterfalls, giant ferns and tropical hardwoods. For an enchanting experience, kayak into the enchanting bioluminescent bay at Laguna Grande of Fajardo on another MSC excursion. Under the blanket of the night sky and the lighthouse of Fajardo, paddle through the water and watch it glow with the bioluminescence of millions and millions of tiny organisms.

Cartagena, Colombia

Cobbled streets, balconies overflowing with blooming bougainvillea and pastel-coloured buildings lining elegant plazas make Cartagena in Colombia one of the Caribbean's most photogenic cities, and a memorable stop on an MSC Caribbean and Antilles cruise. Founded in 1533, this Spanish colonial city, a UNESCO World Heritage Site, is steeped in history. Its location made it a popular target for plunderers and English pirates, and arguably features the most impressive collection of forts in the Caribbean. Today the city is eager to share its treasures with modern visitors. Magnificent colonial structures such as the 16th-century Santa Catalina Cathedral, with its striking stuccoes and dome tower, and the three-arch clock gate, the Torre del Reloj, are just two of the many landmarks of this enchanting city dotted with many squares and sidewalk cafés. A wonderful photo stop on our Cartagena City MSC excursion is the San Felipe de Barajas fortress, a marvel of colonial Spanish military engineering. Its construction began in 1536. Slaves la-boured for more than 120 years to erect this fortress - built on high ground with dominating ap-proaches to the city by land and sea to fend off pirates - and its network of tunnels. On yet another MSC excursion, enrich your palate as you learn about the rich aromas and flavours of Colombian coffee. Introduced by the Jesuits in 1723, coffee quickly became a key crop in Colombia, which is now one of the top producers of Arabica coffee in the world. Colombia is also the world’s top producer of emeralds. If jewellery and gems fascinate you, learn all about these green precious stones and make your own emerald-studded jewellery in sterling silver during a hands-on MSC excursion that guides you step-by-step. And you don’t need to go far to explore nature. An MSC excursion takes you by canoe through mangrove tunnels to Ciénaga de la Virgen, where you can witness a diversity of birds from king-fishers and white herons to pelicans and pink-feathered roseate spoonbills.

Price tracking

Today’s fare, in context

Price history

Cheaper than 66%
90 days
Fare details

Fare details

Per person · taxes & fees included
Current fares
Verified 2 days ago
Oceanview
$3,000
Balcony
$3,700
Suite
$3,900
Tracked range
150 days
Price history by cabin type
CabinCurrentLowestHighest
Oceanview $3,000 $2,480 on Apr 1 $3,000 on Aug 5
Balcony $3,700 $2,960 on Apr 1 $3,700 on Aug 5
Suite $3,900 $3,120 on Apr 1 $3,900 on Aug 5
Cabin grades
11 total
Double Guest Room with VerandaBalcony · CSVF
Double Guest Room with VerandaBalcony · CSVM
Double Guest Room with Ocean ViewOceanview · CSWM
Single Guest Room with Ocean ViewOceanview · SGWF
Crystal Penthouse SuiteSuite · CHV5
Sapphire Veranda SuiteSuite · GSVF
Sapphire Veranda SuiteSuite · GSVM
Junior Crystal Penthouse SuiteSuite · RYVF
Aquamarine Veranda SuiteSuite · SSVF
Aquamarine Veranda SuiteSuite · SSVM
Aquamarine Ocean View SuiteSuite · SSWM

○ = last seen (sold out or delisted). · Verified 2 days ago.

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Current prices

Per person · 2 guests · incl. taxes & fees

Inside

Not available

Oceanview

from $3,000

$600 / night

Fare rows

Double Guest Room with Ocean View

Cabin grade

Available

from $3,000

$600 / night

per person · incl. taxes & fees

Single Guest Room with Ocean View

Cabin grade

Available

from $3,900

$780 / night

per person · incl. taxes & fees

Balcony

from $3,700

$740 / night

Fare rows

Double Guest Room with Veranda

Cabin grade

Available

from $3,700

$740 / night

per person · incl. taxes & fees

Suite

from $3,900

$780 / night

Fare rows

Aquamarine Veranda Suite

Cabin grade

Available

from $3,900

$780 / night

per person · incl. taxes & fees

Sapphire Veranda Suite

Cabin grade

Available

from $4,200

$840 / night

per person · incl. taxes & fees

Prices verified Aug 25, 2026

Prices come from third-party data feeds via Crystal Cruises and may differ from the cruise line's current fare. Confirm the final price before booking. How our pricing works

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The journey

5 nights, in order

Follow the entire sailing from its first day to its last, with the route and schedule in one view.

San Juan, Puerto Rico

Day 1 Nov 27, 2026

San Juan, Puerto Rico

Blessed with some of the oldest buildings in the Western Hemisphere, San Juan, Puerto Rico’s cap-ital, is romantically charming with its bright pastel Spanish colonial facades,…

Explore San Juan, Puerto Rico

Day by day

The full itinerary

6 scheduled calls
Crystal Serenity

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Crystal Serenity

6★ 68,870 GT 740 Passengers
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