4 nights South America from Santos (Sao Paulo)

4 nights Apr 3, 2027

The 4 nights South America from Santos (Sao Paulo) is a 4-night Brazil cruise aboard MSC Virtuosa, operated by MSC Cruises. Departing Sao Paulo on April 3, 2027, the voyage visits 4 ports. Fares start from $1,909 per person.

from $1,909

$477 / night per person, incl. taxes & fees

See prices

You'll continue on MSC Cruises's official site. Affiliate disclosure

from $1,909 pp

Continues on MSC Cruises's site

See prices

Itinerary

Day 1 Apr 3, 2027 Sao Paulo Departs 18:00 São Paulo, Brazil’s vibrant financial center, is among the world's most populous cities, with numerous cultural institutions and a rich architectural tradition. Its iconic buildings range from its neo-Gothic cathedral and the 1929 Martinelli skyscraper to modernist architect Oscar Niemeyer’s curvy Edifício Copan. The colonial-style Pátio do Colégio church marks where Jesuit priests founded the city in 1554. Go to Sao Paulo Cruises visiting Sao Paulo

Sao Paulo photo — Day 1 Apr 3, 2027 Sao Paulo Departs 18:00 São Paulo, Brazil’s vibrant financial center, is among the world's most populous cities, with numerous cultural institutions and a rich architectural tradition. Its iconic buildings range from its neo-Gothic cathedral and the 1929 Martinelli skyscraper to modernist architect Oscar Niemeyer’s curvy Edifício Copan. The colonial-style Pátio do Colégio church marks where Jesuit priests founded the city in 1554. Go to Sao Paulo Cruises visiting Sao Paulo

Day 2 Apr 4, 2027 Rio de Janeiro 09:00 – 19:00 10.0 hrs ashore As you’ll be able to appreciate when you cruise the Atlantic Ocean with MSC Cruises, in its position on the southern shore of the magnificent Guanabara Bay, Rio de Janeiro has, without a shadow of a doubt, one of the most stunning settings in the world. Extending for 20km along an alluvial strip, between an azure sea and forest-clad mountains, the city’s streets and buildings have been moulded around the foothills of the mountain range that provides its backdrop, while out in the bay there are many rocky islands fringed with white sand. The aerial views over Rio are breathtaking, and even the concrete skyscrapers that dominate the city’s skyline add to the attraction. As the former capital of Brazil and now its second-largest city, Rio has a remarkable architectural heritage, some of the country’s best museums and galleries, superb restaurants and a vibrant nightlife – in addition to its legendary beaches. A shore excursion on your MSC South America cruise can be the opportunity to visit the Pão de Açúcar. The Sugar Loaf Mountain rises where Guanabara Bay meets the Atlantic Ocean. Its name may simply reflect a resemblance to the moulded loaves in which sugar was once commonly sold. Alternatively, it may be a corruption of the indigenous Tamoya word Pau-nh-Açuquá, meaning “high, pointed or isolated hill”. On the top of Corcoavado Mountain instead the Art Deco statue of Cristo Redentor (Christ the Redeemer), arms outstretched in welcome, stands 30m high and weighs over 1000 tonnes. It was supposed to be completed for Brazil’s centenary independence celebrations in 1922, but wasn’t actually finished until 1931. In clear weather, fear no anticlimax: climbing to the statue is a stunning experience, with the whole of Rio and Guanabara Bay laid out before you. Go to Rio de Janeiro Cruises visiting Rio de Janeiro

Rio de Janeiro photo — Day 2 Apr 4, 2027 Rio de Janeiro 09:00 – 19:00 10.0 hrs ashore As you’ll be able to appreciate when you cruise the Atlantic Ocean with MSC Cruises, in its position on the southern shore of the magnificent Guanabara Bay, Rio de Janeiro has, without a shadow of a doubt, one of the most stunning settings in the world. Extending for 20km along an alluvial strip, between an azure sea and forest-clad mountains, the city’s streets and buildings have been moulded around the foothills of the mountain range that provides its backdrop, while out in the bay there are many rocky islands fringed with white sand. The aerial views over Rio are breathtaking, and even the concrete skyscrapers that dominate the city’s skyline add to the attraction. As the former capital of Brazil and now its second-largest city, Rio has a remarkable architectural heritage, some of the country’s best museums and galleries, superb restaurants and a vibrant nightlife – in addition to its legendary beaches. A shore excursion on your MSC South America cruise can be the opportunity to visit the Pão de Açúcar. The Sugar Loaf Mountain rises where Guanabara Bay meets the Atlantic Ocean. Its name may simply reflect a resemblance to the moulded loaves in which sugar was once commonly sold. Alternatively, it may be a corruption of the indigenous Tamoya word Pau-nh-Açuquá, meaning “high, pointed or isolated hill”. On the top of Corcoavado Mountain instead the Art Deco statue of Cristo Redentor (Christ the Redeemer), arms outstretched in welcome, stands 30m high and weighs over 1000 tonnes. It was supposed to be completed for Brazil’s centenary independence celebrations in 1922, but wasn’t actually finished until 1931. In clear weather, fear no anticlimax: climbing to the statue is a stunning experience, with the whole of Rio and Guanabara Bay laid out before you. Go to Rio de Janeiro Cruises visiting Rio de Janeiro

Day 3 Apr 5, 2027 Buzios 07:00 – 18:00 11.0 hrs ashore On a peninsula north of Cabo Frio, Armação dos Búzios, or just Búzios, is an immensely scenic resort full of high-spending beautiful people, and a very popular port of call on holidays to Brazil with MSC Cruises. Armação, the main settlement, is built in a vaguely colonial style, its streets lined with restaurants, bars and chic boutiques, and has been nicknamed “Brazil’s St Tropez”. It comes then as little surprise to find that it was “discovered” by none other than Brigitte Bardot, who stumbled upon it while touring the area in 1964. Búzios consists of three main settlements, Manguinos, Armação and Ossos, each with its own distinct character. Manguinos, on the isthmus, is the main service centre, with a tourist office, a medical centre and banks. Midway along the peninsula, linked to Manguinos by a road lined with brash hotels, is Armação, an attractive village where cars are banned from some of the cobbled roads. Most of Búzio’s best restaurants and boutiques are concentrated here, along with some of the resort’s nicest pousadas, or inns, and there’s also a helpful tourist office on the main square, Praça Santos Dumont. When you step ashore from your MSC cruise, a fifteen-minute walk along the Orla Bardot – which follows the coast from Armação, passing the lovely seventeenth-century Igreja de NossaSenhora de Sant’Ana on the way –, brings you to Ossos, the oldest settlement, comprising a pretty harbour, a quiet beach and a few bars, restaurants and pousadas. Within walking distance of all Búzios’ settlements are beautiful white-sand beaches – 27 in total – cradled between rocky cliffs and promontories, and lapped by crystal-clear waters. The beaches are varied, with the north-facing ones having the calmest and warmest seas, while those facing the south and east have the most surf. Go to Buzios Cruises visiting Buzios

Buzios photo — Day 3 Apr 5, 2027 Buzios 07:00 – 18:00 11.0 hrs ashore On a peninsula north of Cabo Frio, Armação dos Búzios, or just Búzios, is an immensely scenic resort full of high-spending beautiful people, and a very popular port of call on holidays to Brazil with MSC Cruises. Armação, the main settlement, is built in a vaguely colonial style, its streets lined with restaurants, bars and chic boutiques, and has been nicknamed “Brazil’s St Tropez”. It comes then as little surprise to find that it was “discovered” by none other than Brigitte Bardot, who stumbled upon it while touring the area in 1964. Búzios consists of three main settlements, Manguinos, Armação and Ossos, each with its own distinct character. Manguinos, on the isthmus, is the main service centre, with a tourist office, a medical centre and banks. Midway along the peninsula, linked to Manguinos by a road lined with brash hotels, is Armação, an attractive village where cars are banned from some of the cobbled roads. Most of Búzio’s best restaurants and boutiques are concentrated here, along with some of the resort’s nicest pousadas, or inns, and there’s also a helpful tourist office on the main square, Praça Santos Dumont. When you step ashore from your MSC cruise, a fifteen-minute walk along the Orla Bardot – which follows the coast from Armação, passing the lovely seventeenth-century Igreja de NossaSenhora de Sant’Ana on the way –, brings you to Ossos, the oldest settlement, comprising a pretty harbour, a quiet beach and a few bars, restaurants and pousadas. Within walking distance of all Búzios’ settlements are beautiful white-sand beaches – 27 in total – cradled between rocky cliffs and promontories, and lapped by crystal-clear waters. The beaches are varied, with the north-facing ones having the calmest and warmest seas, while those facing the south and east have the most surf. Go to Buzios Cruises visiting Buzios

Day 5 Apr 7, 2027 Salvador Arrives 09:00 High above the enormous bay of Todos os Santos (All Saints), where your MSC cruise ship awaits your return, Salvador de Bahia has an electric feel from the moment you arrive. This is the great cultural and historical centre of Brazil, where Afro-Brazilian heritage is strongest and where capoeira, candomblé and samba de roda were created. MSC South America cruises offer excursions to the centro histórico of this magical place, a melange of narrow cobbled streets, peeling purple walls, grand Baroque churches, kids kicking footballs, rastas, locals sipping bottled beer on plastic chairs, the wafting aroma of herbs and the almost constant beating of drums, especially as the sun sets. Beyond the old town Salvador is a vast, sprawling city, with a vibrant beach life, modern skyscrapers and plenty of favelas. The centro histórico is the traditional heart of Salvador; it’s built around the craggy, 70m-high bluff that dominates the eastern side of the bay, and is split into upper and lower sections. Cidade Alta (or simply “Centro”) is strung along its top, linked to the less interesting Cidade Baixa (the old commercial centre, aka “Comércio”) by precipitous streets and the towering Art Deco lift-shaft of the Elevador Lacerda. Cidade Alta is the cultural centre of the city, and the section known as the Pelourinho is the groovy old district with colourful and hilly winding streets, its most vibrant and beguiling neighbourhood. The best spot to begin a walking tour of the city is at the Praça Municipal, the square dominated by the impressive Palácio do Rio Branco, the old governor’s palace which was in use until 1979. The fine interior is a blend of Rococo plasterwork, polished wooden floors and painted walls and ceilings. Go to Salvador Cruises visiting Salvador

Salvador photo — Day 5 Apr 7, 2027 Salvador Arrives 09:00 High above the enormous bay of Todos os Santos (All Saints), where your MSC cruise ship awaits your return, Salvador de Bahia has an electric feel from the moment you arrive. This is the great cultural and historical centre of Brazil, where Afro-Brazilian heritage is strongest and where capoeira, candomblé and samba de roda were created. MSC South America cruises offer excursions to the centro histórico of this magical place, a melange of narrow cobbled streets, peeling purple walls, grand Baroque churches, kids kicking footballs, rastas, locals sipping bottled beer on plastic chairs, the wafting aroma of herbs and the almost constant beating of drums, especially as the sun sets. Beyond the old town Salvador is a vast, sprawling city, with a vibrant beach life, modern skyscrapers and plenty of favelas. The centro histórico is the traditional heart of Salvador; it’s built around the craggy, 70m-high bluff that dominates the eastern side of the bay, and is split into upper and lower sections. Cidade Alta (or simply “Centro”) is strung along its top, linked to the less interesting Cidade Baixa (the old commercial centre, aka “Comércio”) by precipitous streets and the towering Art Deco lift-shaft of the Elevador Lacerda. Cidade Alta is the cultural centre of the city, and the section known as the Pelourinho is the groovy old district with colourful and hilly winding streets, its most vibrant and beguiling neighbourhood. The best spot to begin a walking tour of the city is at the Praça Municipal, the square dominated by the impressive Palácio do Rio Branco, the old governor’s palace which was in use until 1979. The fine interior is a blend of Rococo plasterwork, polished wooden floors and painted walls and ceilings. Go to Salvador Cruises visiting Salvador

Pricing

Lowest fare we've tracked over the observed 90-day span: $399 · range $399–$1,909

Current prices

Per person · 2 guests · incl. taxes & fees

Inside

Not available

Oceanview

Not available

Balcony

Not available

Suite

from $1,909

$477 / night

Fare rows

MSC Yacht Club Deluxe Suite

Cabin grade

Available

from $1,909

$477 / night

per person · incl. taxes

MSC Yacht Club Deluxe Suite

Cabin grade

Available

from $1,909

$477 / night

per person · incl. taxes

Prices verified Jun 21, 2026

Prices come from third-party data feeds via MSC Cruises and may differ from the cruise line's current fare. Confirm the final price before booking. How our pricing works

Show all 23 cabin grades

Name	Supplier code	Type
Balcony Aurea	BA	Balcony
Balcony Bella	BB	Balcony
Deluxe Balcony With Partial View FANTASTICA	BP	Balcony
Deluxe Balcony FANTASTICA	BR1	Balcony
Deluxe Balcony FANTASTICA	BR2	Balcony
Deluxe Balcony FANTASTICA	BR3	Balcony
Studio Balcony FANTASTICA	BS	Balcony
Interior Bella	IB	Inside
Deluxe Interior FANTASTICA	IR1	Inside
Deluxe Interior FANTASTICA	IR2	Inside
Studio Interior FANTASTICA	IS	Inside
Ocean View Bella	OB	Oceanview
Premium Ocean View FANTASTICA	OL2	Oceanview
Junior Ocean View FANTASTICA	OM2	Oceanview
Junior Ocean View with obstructed view FANTASTICA	OO	Oceanview
Deluxe Ocean View FANTASTICA	OR1	Oceanview
Premium Suite Aurea	SL1	Suite
Premium Suite Aurea with Terrace and Whirlpool	SLJ	Suite
Grand Suite Aurea with Terrace and Whirlpool	SXJ	Suite
MSC Yacht Club Deluxe Suite	YC1	Suite
MSC Yacht Club Royal Suite with Whirlpool Bath	YC3	Suite
Yacht Club Interior Suite	YIN	Suite
MSC Yacht Club Duplex Suite with Jacuzzi	YJD	Suite