16 nights South America from Genoa (Portofino)

The 16 nights South America from Genoa (Portofino) is a 16-night Western Mediterranean cruise aboard MSC Divina, operated by MSC Cruises. Departing Genoa, Italy on October 31, 2026, the voyage visits 6 ports. Fares start from $1,138 per person.

Length: 16 nights
Departs: Oct 31, 2026
Returns: Nov 16, 2026
Ports of call: 6
Days at sea: 11

from $1,138

$71 / night per person, incl. taxes & fees

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Itinerary

Day 1 Oct 31, 2026 Genoa, Italy Departs 18:00 Genoa is marvellously eclectic, vibrant and full of rough-edged style; it’s a great cruise excursion. Indeed “La Superba” (The Superb), as it was known at the height of its authority as a Mediterranean superpower, boasts more zest and intrigue than all the surrounding coastal resorts put together. During a holiday to Genoa you can explore its old town: a dense and fascinating warren of medieval alleyways home to large palazzi built in the sixteenth and seventeenth centuries by Genoa’s wealthy mercantile families and now transformed into museums and art galleries. You should seek out the Cattedrale di San Lorenzo, the Palazzo Ducale, and the Renaissance palaces of Via Garibaldi which contain the cream of Genoa’s art collections, as well as furniture and decor from the grandest days of the city’s past, when its ships sailed to all corners of the Mediterranean Sea. The Acquario di Genova is the city’s pride and joy, parked like a giant ocean liner on the waterfront, with seventy tanks housing sea creatures from all the world’s major habitats, including the world’s biggest reconstruction of a Caribbean coral reef. It’s a great aquarium by any standards, the second largest in Europe by capacity, and boasts a fashionably ecology-conscious slant and excellent background information in Italian and English. Just 35 km south of Genoa, there’s no denying the appeal of Portofino, tucked into a protected inlet surrounded by lush cypress- and olive-clad slopes. It’s an A-list resort that has been attracting high-flying bankers, celebs and their hangers-on for years, as evidenced by the flotillas of giant yachts usually anchored just outside. It’s a tiny place that is attractive yet somehow off-putting at the same time, with a quota of fancy shops, bars and restaurants for a place twice its size. Genoa, Italy port guide Search cruises visiting Genoa, Italy

Genoa, Italy photo — Day 1 Oct 31, 2026 Genoa, Italy Departs 18:00 Genoa is marvellously eclectic, vibrant and full of rough-edged style; it’s a great cruise excursion. Indeed “La Superba” (The Superb), as it was known at the height of its authority as a Mediterranean superpower, boasts more zest and intrigue than all the surrounding coastal resorts put together. During a holiday to Genoa you can explore its old town: a dense and fascinating warren of medieval alleyways home to large palazzi built in the sixteenth and seventeenth centuries by Genoa’s wealthy mercantile families and now transformed into museums and art galleries. You should seek out the Cattedrale di San Lorenzo, the Palazzo Ducale, and the Renaissance palaces of Via Garibaldi which contain the cream of Genoa’s art collections, as well as furniture and decor from the grandest days of the city’s past, when its ships sailed to all corners of the Mediterranean Sea. The Acquario di Genova is the city’s pride and joy, parked like a giant ocean liner on the waterfront, with seventy tanks housing sea creatures from all the world’s major habitats, including the world’s biggest reconstruction of a Caribbean coral reef. It’s a great aquarium by any standards, the second largest in Europe by capacity, and boasts a fashionably ecology-conscious slant and excellent background information in Italian and English. Just 35 km south of Genoa, there’s no denying the appeal of Portofino, tucked into a protected inlet surrounded by lush cypress- and olive-clad slopes. It’s an A-list resort that has been attracting high-flying bankers, celebs and their hangers-on for years, as evidenced by the flotillas of giant yachts usually anchored just outside. It’s a tiny place that is attractive yet somehow off-putting at the same time, with a quota of fancy shops, bars and restaurants for a place twice its size. Genoa, Italy port guide Search cruises visiting Genoa, Italy

Day 3 Nov 2, 2026 Tarragona 08:00 – 18:00 10.0 hrs ashore Tarragona, port city of Spain, is located less than 100 km from Barcelona from the top of its walls, here you can admire one of the most important Gothic cathedrals in Catalonia and the immense amphitheatre, stage for gladiatorial combat in Roman times. During your Mediterranean cruise, you will visit the Port of Tarragona; a true gem, with Roman ruins that are the pride of its residents and historical traditions that are part of the local folklore. The Roman heritage is still part of the urban context in Tarragona. Here, you can watch the reenactments of the centurion parades and gladiatorial combat. During the stop in the port of Tarragona, proceed to the Praetorian Tower. On the first floor there is a model of the medieval town and its glory that was lost during a war that is still commemorated with solemn candles on the steps of the cathedral. If you have the time, watch the races of human pyramids that are organised in various districts of the city. Tarragona port guide Search cruises visiting Tarragona

Tarragona photo — Day 3 Nov 2, 2026 Tarragona 08:00 – 18:00 10.0 hrs ashore Tarragona, port city of Spain, is located less than 100 km from Barcelona from the top of its walls, here you can admire one of the most important Gothic cathedrals in Catalonia and the immense amphitheatre, stage for gladiatorial combat in Roman times. During your Mediterranean cruise, you will visit the Port of Tarragona; a true gem, with Roman ruins that are the pride of its residents and historical traditions that are part of the local folklore. The Roman heritage is still part of the urban context in Tarragona. Here, you can watch the reenactments of the centurion parades and gladiatorial combat. During the stop in the port of Tarragona, proceed to the Praetorian Tower. On the first floor there is a model of the medieval town and its glory that was lost during a war that is still commemorated with solemn candles on the steps of the cathedral. If you have the time, watch the races of human pyramids that are organised in various districts of the city. Tarragona port guide Search cruises visiting Tarragona

Day 6 Nov 5, 2026 Santa Cruz de Tenerife 08:00 – 18:00 10.0 hrs ashore The old town is a treasury of 16th and 17th century buildings, and not just churches. Do go inside the fortified-looking Iglesia del Salvador, however, to see its ornate, Islamic-style Mudejar ceiling, one of the best in the islands. A short way outside town is the Sanctuary of the Virgin of the Snows, one of the most important sites on the island. The waterfront is a good place to find ancient houses with elaborate iron balconies, many now converted to restaurants and shops. Many visitors tour the island’s dormant volcanoes, or the odd, erosion caldera called La Cumbrecita, a UNESCO Biosphere Site. An excursion to the village of Mazo rewards with a fine island museum containing examples of local handicrafts and especially the fabulous indigenous embroidery. Just beyond the museum is a handicrafts school, an excellent place to acquire a handcrafted souvenir of your Canary Islands adventure. Santa Cruz de Tenerife port guide Search cruises visiting Santa Cruz de Tenerife

Santa Cruz de Tenerife photo — Day 6 Nov 5, 2026 Santa Cruz de Tenerife 08:00 – 18:00 10.0 hrs ashore The old town is a treasury of 16th and 17th century buildings, and not just churches. Do go inside the fortified-looking Iglesia del Salvador, however, to see its ornate, Islamic-style Mudejar ceiling, one of the best in the islands. A short way outside town is the Sanctuary of the Virgin of the Snows, one of the most important sites on the island. The waterfront is a good place to find ancient houses with elaborate iron balconies, many now converted to restaurants and shops. Many visitors tour the island’s dormant volcanoes, or the odd, erosion caldera called La Cumbrecita, a UNESCO Biosphere Site. An excursion to the village of Mazo rewards with a fine island museum containing examples of local handicrafts and especially the fabulous indigenous embroidery. Just beyond the museum is a handicrafts school, an excellent place to acquire a handcrafted souvenir of your Canary Islands adventure. Santa Cruz de Tenerife port guide Search cruises visiting Santa Cruz de Tenerife

Day 13 Nov 12, 2026 Salvador 08:00 – 18:00 10.0 hrs ashore High above the enormous bay of Todos os Santos (All Saints), where your MSC cruise ship awaits your return, Salvador de Bahia has an electric feel from the moment you arrive. This is the great cultural and historical centre of Brazil, where Afro-Brazilian heritage is strongest and where capoeira, candomblé and samba de roda were created. MSC South America cruises offer excursions to the centro histórico of this magical place, a melange of narrow cobbled streets, peeling purple walls, grand Baroque churches, kids kicking footballs, rastas, locals sipping bottled beer on plastic chairs, the wafting aroma of herbs and the almost constant beating of drums, especially as the sun sets. Beyond the old town Salvador is a vast, sprawling city, with a vibrant beach life, modern skyscrapers and plenty of favelas. The centro histórico is the traditional heart of Salvador; it’s built around the craggy, 70m-high bluff that dominates the eastern side of the bay, and is split into upper and lower sections. Cidade Alta (or simply “Centro”) is strung along its top, linked to the less interesting Cidade Baixa (the old commercial centre, aka “Comércio”) by precipitous streets and the towering Art Deco lift-shaft of the Elevador Lacerda. Cidade Alta is the cultural centre of the city, and the section known as the Pelourinho is the groovy old district with colourful and hilly winding streets, its most vibrant and beguiling neighbourhood. The best spot to begin a walking tour of the city is at the Praça Municipal, the square dominated by the impressive Palácio do Rio Branco, the old governor’s palace which was in use until 1979. The fine interior is a blend of Rococo plasterwork, polished wooden floors and painted walls and ceilings. Salvador port guide Search cruises visiting Salvador

Salvador photo — Day 13 Nov 12, 2026 Salvador 08:00 – 18:00 10.0 hrs ashore High above the enormous bay of Todos os Santos (All Saints), where your MSC cruise ship awaits your return, Salvador de Bahia has an electric feel from the moment you arrive. This is the great cultural and historical centre of Brazil, where Afro-Brazilian heritage is strongest and where capoeira, candomblé and samba de roda were created. MSC South America cruises offer excursions to the centro histórico of this magical place, a melange of narrow cobbled streets, peeling purple walls, grand Baroque churches, kids kicking footballs, rastas, locals sipping bottled beer on plastic chairs, the wafting aroma of herbs and the almost constant beating of drums, especially as the sun sets. Beyond the old town Salvador is a vast, sprawling city, with a vibrant beach life, modern skyscrapers and plenty of favelas. The centro histórico is the traditional heart of Salvador; it’s built around the craggy, 70m-high bluff that dominates the eastern side of the bay, and is split into upper and lower sections. Cidade Alta (or simply “Centro”) is strung along its top, linked to the less interesting Cidade Baixa (the old commercial centre, aka “Comércio”) by precipitous streets and the towering Art Deco lift-shaft of the Elevador Lacerda. Cidade Alta is the cultural centre of the city, and the section known as the Pelourinho is the groovy old district with colourful and hilly winding streets, its most vibrant and beguiling neighbourhood. The best spot to begin a walking tour of the city is at the Praça Municipal, the square dominated by the impressive Palácio do Rio Branco, the old governor’s palace which was in use until 1979. The fine interior is a blend of Rococo plasterwork, polished wooden floors and painted walls and ceilings. Salvador port guide Search cruises visiting Salvador

Day 16 Nov 15, 2026 Rio de Janeiro 08:00 – 18:00 10.0 hrs ashore As you’ll be able to appreciate when you cruise the Atlantic Ocean with MSC Cruises, in its position on the southern shore of the magnificent Guanabara Bay, Rio de Janeiro has, without a shadow of a doubt, one of the most stunning settings in the world. Extending for 20km along an alluvial strip, between an azure sea and forest-clad mountains, the city’s streets and buildings have been moulded around the foothills of the mountain range that provides its backdrop, while out in the bay there are many rocky islands fringed with white sand. The aerial views over Rio are breathtaking, and even the concrete skyscrapers that dominate the city’s skyline add to the attraction. As the former capital of Brazil and now its second-largest city, Rio has a remarkable architectural heritage, some of the country’s best museums and galleries, superb restaurants and a vibrant nightlife – in addition to its legendary beaches. A shore excursion on your MSC South America cruise can be the opportunity to visit the Pão de Açúcar. The Sugar Loaf Mountain rises where Guanabara Bay meets the Atlantic Ocean. Its name may simply reflect a resemblance to the moulded loaves in which sugar was once commonly sold. Alternatively, it may be a corruption of the indigenous Tamoya word Pau-nh-Açuquá, meaning “high, pointed or isolated hill”. On the top of Corcoavado Mountain instead the Art Deco statue of Cristo Redentor (Christ the Redeemer), arms outstretched in welcome, stands 30m high and weighs over 1000 tonnes. It was supposed to be completed for Brazil’s centenary independence celebrations in 1922, but wasn’t actually finished until 1931. In clear weather, fear no anticlimax: climbing to the statue is a stunning experience, with the whole of Rio and Guanabara Bay laid out before you. Rio de Janeiro port guide Search cruises visiting Rio de Janeiro

Rio de Janeiro photo — Day 16 Nov 15, 2026 Rio de Janeiro 08:00 – 18:00 10.0 hrs ashore As you’ll be able to appreciate when you cruise the Atlantic Ocean with MSC Cruises, in its position on the southern shore of the magnificent Guanabara Bay, Rio de Janeiro has, without a shadow of a doubt, one of the most stunning settings in the world. Extending for 20km along an alluvial strip, between an azure sea and forest-clad mountains, the city’s streets and buildings have been moulded around the foothills of the mountain range that provides its backdrop, while out in the bay there are many rocky islands fringed with white sand. The aerial views over Rio are breathtaking, and even the concrete skyscrapers that dominate the city’s skyline add to the attraction. As the former capital of Brazil and now its second-largest city, Rio has a remarkable architectural heritage, some of the country’s best museums and galleries, superb restaurants and a vibrant nightlife – in addition to its legendary beaches. A shore excursion on your MSC South America cruise can be the opportunity to visit the Pão de Açúcar. The Sugar Loaf Mountain rises where Guanabara Bay meets the Atlantic Ocean. Its name may simply reflect a resemblance to the moulded loaves in which sugar was once commonly sold. Alternatively, it may be a corruption of the indigenous Tamoya word Pau-nh-Açuquá, meaning “high, pointed or isolated hill”. On the top of Corcoavado Mountain instead the Art Deco statue of Cristo Redentor (Christ the Redeemer), arms outstretched in welcome, stands 30m high and weighs over 1000 tonnes. It was supposed to be completed for Brazil’s centenary independence celebrations in 1922, but wasn’t actually finished until 1931. In clear weather, fear no anticlimax: climbing to the statue is a stunning experience, with the whole of Rio and Guanabara Bay laid out before you. Rio de Janeiro port guide Search cruises visiting Rio de Janeiro

Day 17 Nov 16, 2026 Sao Paulo Arrives 08:00 São Paulo, Brazil’s vibrant financial center, is among the world's most populous cities, with numerous cultural institutions and a rich architectural tradition. Its iconic buildings range from its neo-Gothic cathedral and the 1929 Martinelli skyscraper to modernist architect Oscar Niemeyer’s curvy Edifício Copan. The colonial-style Pátio do Colégio church marks where Jesuit priests founded the city in 1554. Sao Paulo port guide Search cruises visiting Sao Paulo

Sao Paulo photo — Day 17 Nov 16, 2026 Sao Paulo Arrives 08:00 São Paulo, Brazil’s vibrant financial center, is among the world's most populous cities, with numerous cultural institutions and a rich architectural tradition. Its iconic buildings range from its neo-Gothic cathedral and the 1929 Martinelli skyscraper to modernist architect Oscar Niemeyer’s curvy Edifício Copan. The colonial-style Pátio do Colégio church marks where Jesuit priests founded the city in 1554. Sao Paulo port guide Search cruises visiting Sao Paulo

Pricing

Lowest fare we've tracked over the observed 85-day span: $1,112 · range $1,112–$1,222

Lower than 60% of peers This extended sailing's from-price per night is lower than 60% of comparable sailings.

same cruise line and duration · from-price per night · as of Jun 24, 2026 · Broader cohort: same cruise line and duration, compared by from-price per night.

Current prices

Per person · 2 guests · incl. taxes & fees

Inside

from $1,138

$71 / night

Fare rows

INTERIOR BELLA GUARANTEED

Cabin grade

Available

from $1,138

$71 / night

per person · incl. taxes

JUNIOR INTERIOR FANTASTICA

Cabin grade

Available

from $1,228

$76 / night

per person · incl. taxes

DELUXE INTERIOR FANTASTICA

Cabin grade

Available

from $1,248

$78 / night

per person · incl. taxes

DELUXE INTERIOR FANTASTICA

Cabin grade

Available

from $1,268

$79 / night

per person · incl. taxes

INTERIOR BELLA GUARANTEED

Cabin grade

Available

from $2,002

$125 / night

per person · incl. taxes

JUNIOR INTERIOR FANTASTICA

Cabin grade

Available

from $2,092

$130 / night

per person · incl. taxes

DELUXE INTERIOR FANTASTICA

Cabin grade

Available

from $2,112

$132 / night

per person · incl. taxes

INTERIOR BELLA GUARANTEED

Cabin grade

Available

from $2,113

$132 / night

per person · incl. taxes

DELUXE INTERIOR FANTASTICA

Cabin grade

Available

from $2,132

$133 / night

per person · incl. taxes

JUNIOR INTERIOR FANTASTICA

Cabin grade

Available

from $2,293

$143 / night

per person · incl. taxes

DELUXE INTERIOR FANTASTICA

Cabin grade

Available

from $2,333

$145 / night

per person · incl. taxes

DELUXE INTERIOR FANTASTICA

Cabin grade

Available

from $2,373

$148 / night

per person · incl. taxes

Oceanview

from $1,472

$92 / night

Fare rows

DELUXE OCEAN VIEW FANTASTICA

Cabin grade

Available

from $1,472

$92 / night

per person · incl. taxes

DELUXE OCEAN VIEW FANTASTICA

Cabin grade

Available

from $2,336

$146 / night

per person · incl. taxes

DELUXE OCEAN VIEW FANTASTICA

Cabin grade

Available

from $2,828

$176 / night

per person · incl. taxes

Balcony

from $2,008

$125 / night

Fare rows

PREMIUM BALCONY FANTASTICA

Cabin grade

Available

from $2,008

$125 / night

per person · incl. taxes

PREMIUM BALCONY FANTASTICA

Cabin grade

Available

from $2,028

$126 / night

per person · incl. taxes

BALCONY AUREA

Cabin grade

Available

from $2,318

$144 / night

per person · incl. taxes

PREMIUM BALCONY FANTASTICA

Cabin grade

Available

from $2,872

$179 / night

per person · incl. taxes

PREMIUM BALCONY FANTASTICA

Cabin grade

Available

from $2,892

$180 / night

per person · incl. taxes

BALCONY AUREA

Cabin grade

Available

from $3,182

$198 / night

per person · incl. taxes

PREMIUM BALCONY FANTASTICA

Cabin grade

Available

from $3,899

$243 / night

per person · incl. taxes

PREMIUM BALCONY FANTASTICA

Cabin grade

Available

from $3,939

$246 / night

per person · incl. taxes

BALCONY AUREA

Cabin grade

Available

from $4,519

$282 / night

per person · incl. taxes

Suite

from $3,203

$200 / night

Fare rows

PREMIUM SUITE AUREA WITH SEALED WINDOW

Cabin grade

Available

from $3,203

$200 / night

per person · incl. taxes

PREMIUM SUITE AUREA WITH SEALED WINDOW

Cabin grade

Available

from $4,067

$254 / night

per person · incl. taxes

PREMIUM SUITE AUREA WITH SEALED WINDOW

Cabin grade

Available

from $6,290

$393 / night

per person · incl. taxes

MSC YACHT CLUB DELUXE SUITE

Cabin grade

Available

from $6,316

$394 / night

per person · incl. taxes

MSC YACHT CLUB DELUXE SUITE

Cabin grade

Available

from $6,316

$394 / night

per person · incl. taxes

MSC YACHT CLUB DELUXE SUITE

Cabin grade

Available

from $12,518

$782 / night

per person · incl. taxes

Prices verified Jun 24, 2026

Prices come from third-party data feeds via MSC Cruises and may differ from the cruise line's current fare. Confirm the final price before booking. How our pricing works

Show all 26 cabin grades

Name	Supplier code	Type
BALCONY AUREA	BA	Balcony
BALCONY BELLA GUARANTEED	BB	Balcony
PREMIUM BALCONY FANTASTICA	BL1	Balcony
PREMIUM BALCONY FANTASTICA	BL2	Balcony
PREMIUM BALCONY FANTASTICA	BL3	Balcony
JUNIOR BALCONY FANTASTICA	BM1	Balcony
JUNIOR BALCONY FANTASTICA	BM2	Balcony
DELUXE BALCONY WITH PARTIAL VIEW FANTASTICA	BP	Balcony
INTERIOR BELLA GUARANTEED	IB	Inside
JUNIOR INTERIOR FANTASTICA	IM1	Inside
JUNIOR INTERIOR FANTASTICA	IM2	Inside
DELUXE INTERIOR FANTASTICA	IR1	Inside
DELUXE INTERIOR FANTASTICA	IR2	Inside
OCEAN VIEW BELLA GUARANTEED	OB	Oceanview
PREMIUM OCEAN VIEW FANTASTICA	OL1	Oceanview
JUNIOR OCEAN VIEW FANTASTICA	OM2	Oceanview
DELUXE OCEAN VIEW FANTASTICA	OR2	Oceanview
PREMIUM SUITE AUREA	SL1	Suite
PREMIUM SUITE AUREA WITH SEALED WINDOW	SLS	Suite
JUNIOR SUITE AUREA WITH SEALED WINDOW	SRS	Suite
GRAND SUITE AUREA	SX	Suite
MSC YACHT CLUB DELUXE SUITE	YC1	Suite
MSC YACHT CLUB EXECUTIVE & FAMILY SUITE	YC2	Suite
MSC YACHT CLUB ROYAL SUITE	YC3	Suite
MSC YACHT CLUB DELUXE GRAND SUITE	YCP	Suite
MSC YACHT CLUB YACHT CLUB EXECUTIVE AND FAMILY SUITE WITH BALCONY	YCT	Suite