Cape Girardeau, MO cruise port guide
See a well-preserved fort and uncover this riverside city’s importance during the Civil War.
About Cape Girardeau, MO
Cape Girardeau is a city on the Mississippi River in southeast Missouri, a port of call for river cruise ships navigating the Mississippi system. American Cruise Lines operates paddlewheel cruise ships on much of the Mississippi system.
Quick facts
Cruises visiting Cape Girardeau, MO
Prices per person · incl. taxes & fees.
Sailing soonest
Memphis to Nashville
Viking Mississippi · Worldwide · 7 nights
from $5,799
$828 / night
Memphis to Nashville
Viking Mississippi · Worldwide · 7 nights
from $5,299
$757 / night
Nashville to Memphis
Viking Mississippi · Worldwide · 7 nights
from $4,799
$685 / night
Showing the 14 least-expensive of 14 sailings.
Showing 14 Cape Girardeau, MO cruises
Open in full search| View | Ship image | Cruise line | Line / Ship | Departs | Nights | From |
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Viking | Viking Viking Mississippi | Oct 27, 2026 | 7 |
from $5,799 $828 / night |
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Viking | Viking Viking Mississippi | Nov 10, 2026 | 7 |
from $5,299 $757 / night |
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Viking | Viking Viking Mississippi | Nov 3, 2026 | 7 |
from $5,499 $785 / night |
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Viking | Viking Viking Mississippi | Nov 17, 2026 | 7 |
from $4,799 $685 / night |
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Viking | Viking Viking Mississippi | Jun 22, 2027 | 21 |
Call for price |
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Viking | Viking Viking Mississippi | Jul 6, 2027 | 14 |
from $8,899 $635 / night |
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Viking | Viking Viking Mississippi | Jul 27, 2027 | 21 |
Call for price |
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Viking | Viking Viking Mississippi | Aug 10, 2027 | 14 |
from $8,899 $635 / night |
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Viking | Viking Viking Mississippi | Jul 6, 2027 | 21 |
from $15,498 $738 / night |
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Viking | Viking Viking Mississippi | Aug 10, 2027 | 21 |
from $15,998 $761 / night |
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Viking | Viking Viking Mississippi | Aug 15, 2028 | 21 |
from $15,998 $761 / night |
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Viking | Viking Viking Mississippi | Jul 11, 2028 | 21 |
from $15,998 $761 / night |
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Viking | Viking Viking Mississippi | Jul 11, 2028 | 14 |
from $9,499 $678 / night |
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Viking | Viking Viking Mississippi | Aug 15, 2028 | 14 |
from $9,499 $678 / night |
