Cape Girardeau, MO

Cape Girardeau, MO cruise port guide

About Cape Girardeau, MO

Cape Girardeau is a city on the Mississippi River in southeast Missouri, a port of call for river cruise ships navigating the Mississippi system. American Cruise Lines operates paddlewheel cruise ships on much of the Mississippi system.

Quick facts

Port quick facts
Coordinates	37.3059, -89.5182
Available cruises	18

Cruises visiting Cape Girardeau, MO

Prices per person · incl. taxes & fees.

Sailing soonest

Nashville, Memphis & the Cumberland from Memphis

Viking Mississippi · North America · 7 nights

from $5,799

$828 / night

Oct 27, 2026

Nashville, Memphis & the Cumberland from Nashville

Viking Mississippi · North America · 7 nights

from $5,499

$785 / night

Nov 3, 2026

Nashville, Memphis & the Cumberland from Memphis

Viking Mississippi · North America · 7 nights

from $5,299

$757 / night

Nov 10, 2026

Nashville, Memphis & the Cumberland from Nashville

Viking Mississippi · North America · 7 nights

from $4,799

$685 / night

Nov 17, 2026

Mississippi River Odyssey

Viking Mississippi · North America · 21 nights

Call for price

Jun 22, 2027

The Big Easy to the Gateway City

Viking Mississippi · North America · 14 nights

from $8,999

$642 / night

Jun 22, 2027

Showing the 18 least-expensive of 18 sailings.

Showing 18 Cape Girardeau, MO cruises

Open in full search

Cruises departing from this port
Cruise line	Line / Ship	Departs	Nights	From
Viking Viking line guide Search Cape Girardeau, MO cruises on Viking	Viking Viking line guide Search Cape Girardeau, MO cruises on Viking Viking Mississippi Viking Mississippi ship guide Search cruises on Viking Mississippi	Oct 27, 2026	7	from $5,799 $828 / night
Viking Viking line guide Search Cape Girardeau, MO cruises on Viking	Viking Viking line guide Search Cape Girardeau, MO cruises on Viking Viking Mississippi Viking Mississippi ship guide Search cruises on Viking Mississippi	Nov 10, 2026	7	from $5,299 $757 / night
Viking Viking line guide Search Cape Girardeau, MO cruises on Viking	Viking Viking line guide Search Cape Girardeau, MO cruises on Viking Viking Mississippi Viking Mississippi ship guide Search cruises on Viking Mississippi	Nov 3, 2026	7	from $5,499 $785 / night
Viking Viking line guide Search Cape Girardeau, MO cruises on Viking	Viking Viking line guide Search Cape Girardeau, MO cruises on Viking Viking Mississippi Viking Mississippi ship guide Search cruises on Viking Mississippi	Nov 17, 2026	7	from $4,799 $685 / night
Viking Viking line guide Search Cape Girardeau, MO cruises on Viking	Viking Viking line guide Search Cape Girardeau, MO cruises on Viking Viking Mississippi Viking Mississippi ship guide Search cruises on Viking Mississippi	Jun 22, 2027	21	Call for price
Viking Viking line guide Search Cape Girardeau, MO cruises on Viking	Viking Viking line guide Search Cape Girardeau, MO cruises on Viking Viking Mississippi Viking Mississippi ship guide Search cruises on Viking Mississippi	Jun 22, 2027	14	from $8,999 $642 / night
Viking Viking line guide Search Cape Girardeau, MO cruises on Viking	Viking Viking line guide Search Cape Girardeau, MO cruises on Viking Viking Mississippi Viking Mississippi ship guide Search cruises on Viking Mississippi	Jul 27, 2027	21	Call for price
Viking Viking line guide Search Cape Girardeau, MO cruises on Viking	Viking Viking line guide Search Cape Girardeau, MO cruises on Viking Viking Mississippi Viking Mississippi ship guide Search cruises on Viking Mississippi	Jul 27, 2027	14	from $8,999 $642 / night
Viking Viking line guide Search Cape Girardeau, MO cruises on Viking	Viking Viking line guide Search Cape Girardeau, MO cruises on Viking Viking Mississippi Viking Mississippi ship guide Search cruises on Viking Mississippi	Oct 19, 2027	7	from $6,999 $999 / night
Viking Viking line guide Search Cape Girardeau, MO cruises on Viking	Viking Viking line guide Search Cape Girardeau, MO cruises on Viking Viking Mississippi Viking Mississippi ship guide Search cruises on Viking Mississippi	Oct 26, 2027	7	from $6,999 $999 / night
Viking Viking line guide Search Cape Girardeau, MO cruises on Viking	Viking Viking line guide Search Cape Girardeau, MO cruises on Viking Viking Mississippi Viking Mississippi ship guide Search cruises on Viking Mississippi	Nov 2, 2027	7	from $6,499 $928 / night
Viking Viking line guide Search Cape Girardeau, MO cruises on Viking	Viking Viking line guide Search Cape Girardeau, MO cruises on Viking Viking Mississippi Viking Mississippi ship guide Search cruises on Viking Mississippi	Nov 9, 2027	7	from $5,999 $857 / night
Viking Viking line guide Search Cape Girardeau, MO cruises on Viking	Viking Viking line guide Search Cape Girardeau, MO cruises on Viking Viking Mississippi Viking Mississippi ship guide Search cruises on Viking Mississippi	Jul 6, 2027	21	from $15,498 $738 / night
Viking Viking line guide Search Cape Girardeau, MO cruises on Viking	Viking Viking line guide Search Cape Girardeau, MO cruises on Viking Viking Mississippi Viking Mississippi ship guide Search cruises on Viking Mississippi	Aug 10, 2027	21	from $15,998 $761 / night
Viking Viking line guide Search Cape Girardeau, MO cruises on Viking	Viking Viking line guide Search Cape Girardeau, MO cruises on Viking Viking Mississippi Viking Mississippi ship guide Search cruises on Viking Mississippi	Aug 15, 2028	21	from $15,998 $761 / night
Viking Viking line guide Search Cape Girardeau, MO cruises on Viking	Viking Viking line guide Search Cape Girardeau, MO cruises on Viking Viking Mississippi Viking Mississippi ship guide Search cruises on Viking Mississippi	Jul 11, 2028	21	from $15,998 $761 / night
Viking Viking line guide Search Cape Girardeau, MO cruises on Viking	Viking Viking line guide Search Cape Girardeau, MO cruises on Viking Viking Mississippi Viking Mississippi ship guide Search cruises on Viking Mississippi	Jul 11, 2028	14	from $9,499 $678 / night
Viking Viking line guide Search Cape Girardeau, MO cruises on Viking	Viking Viking line guide Search Cape Girardeau, MO cruises on Viking Viking Mississippi Viking Mississippi ship guide Search cruises on Viking Mississippi	Aug 15, 2028	14	from $9,499 $678 / night