14-night Southeast Asia cruise on Mekong Serenity

The Vietnam and Cambodia Highlights - Siem Reap is a 14-night Southeast Asia cruise aboard Mekong Serenity, operated by APT Cruising. Departing Siem Reap on October 30, 2026, the voyage visits 9 ports.

Length: 14 nights
Departs: Oct 30, 2026
Returns: Nov 13, 2026
Ports of call: 9

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Itinerary

Day 1 Oct 30, 2026 Board in Siem Reap

Siem Reap photo — Day 2 Oct 31, 2026 Siem Reap Siem Reap, a resort town in northwestern Cambodia, is the gateway to the ruins of Angkor, the seat of the Khmer kingdom from the 9th–15th centuries. Angkor’s vast complex of intricate stone buildings includes preserved Angkor Wat, the main temple, which is pictured on Cambodia’s flag. Giant, mysterious faces are carved into the Bayon Temple at Angkor Thom. Siem Reap port guide Search cruises visiting Siem Reap

Day 6 Nov 4, 2026 Angkor Angkor was the capital city of the Khmer Empire. The city and empire flourished from approximately the 9th to the 15th centuries. The city houses the magnificent Angkor Wat, one of Cambodia's most popular tourist attractions. The word Angkor is derived from the Sanskrit nagara, meaning "city". Angkor port guide Search cruises visiting Angkor

Angkor photo — Day 6 Nov 4, 2026 Angkor Angkor was the capital city of the Khmer Empire. The city and empire flourished from approximately the 9th to the 15th centuries. The city houses the magnificent Angkor Wat, one of Cambodia's most popular tourist attractions. The word Angkor is derived from the Sanskrit nagara, meaning "city". Angkor port guide Search cruises visiting Angkor

Day 7 Nov 5, 2026 Phnom Penh Phnom Penh, Cambodia’s busy capital, sits at the junction of the Mekong and Tonlé Sap rivers. It was a hub for both the Khmer Empire and French colonialists. On its walkable riverfront, lined with parks, restaurants and bars, are the ornate Royal Palace, Silver Pagoda and the National Museum, displaying artifacts from around the country. At the city’s heart is the massive, art deco Central Market. Phnom Penh port guide Search cruises visiting Phnom Penh

Phnom Penh photo — Day 7 Nov 5, 2026 Phnom Penh Phnom Penh, Cambodia’s busy capital, sits at the junction of the Mekong and Tonlé Sap rivers. It was a hub for both the Khmer Empire and French colonialists. On its walkable riverfront, lined with parks, restaurants and bars, are the ornate Royal Palace, Silver Pagoda and the National Museum, displaying artifacts from around the country. At the city’s heart is the massive, art deco Central Market. Phnom Penh port guide Search cruises visiting Phnom Penh

Day 7 Nov 5, 2026 Oudong Oudong is a town in Cambodia, at the base of Phnom Udong Mountain, northwest of Phnom Penh. It was the site of the royal capital from the 17th to the 19th centuries. The mountain’s 2 mounds are connected by a ridge and dotted with stupas and shrines dedicated to former kings. Chedi Mouk Pruhm is the burial site of King Monivong. The ruins of Arthross Temple house a large golden Buddha. Oudong port guide Search cruises visiting Oudong

Oudong photo — Day 7 Nov 5, 2026 Oudong Oudong is a town in Cambodia, at the base of Phnom Udong Mountain, northwest of Phnom Penh. It was the site of the royal capital from the 17th to the 19th centuries. The mountain’s 2 mounds are connected by a ridge and dotted with stupas and shrines dedicated to former kings. Chedi Mouk Pruhm is the burial site of King Monivong. The ruins of Arthross Temple house a large golden Buddha. Oudong port guide Search cruises visiting Oudong

Day 10 Nov 8, 2026 Tan Chau Tân Châu is a town of An Giang Province in the Mekong Delta region of Vietnam. As of 2009 the town had a population of 184,129. The town covers an area of 175.68 km². It is famous for Tân Châu silk with the famous product Lãnh Mỹ A, whose black colour comes from the Diospyros mollis's fruit. Tan Chau port guide Search cruises visiting Tan Chau

Tan Chau photo — Day 10 Nov 8, 2026 Tan Chau Tân Châu is a town of An Giang Province in the Mekong Delta region of Vietnam. As of 2009 the town had a population of 184,129. The town covers an area of 175.68 km². It is famous for Tân Châu silk with the famous product Lãnh Mỹ A, whose black colour comes from the Diospyros mollis's fruit. Tan Chau port guide Search cruises visiting Tan Chau

Day 12 Nov 10, 2026 Ho Chi Minh City Ho Chi Minh City is a vibrant port of call for MSC cruise liners on MSC Grand Voyages cruise itineraries. It’s a fury of sights and sounds, and the crucible in which Vietnam’s rallying fortunes are boiling. Few corners of the city afford respite from the cacophony of construction work casting up new office blocks and hotels with logic-defying speed. An increasing number of cars and minibuses jostle with an organic mass of state-of-the-art Honda SUVs, choking the tree-lined streets and boulevards. Amid this melee, the local people go about their daily life: smartly dressed schoolkids wander past streetside baguette-sellers; women shoppers ride motorbikes clad in gangster-style bandanas to protect their skin from the sun and dust; while teenagers in designer jeans chirrup into mobile phones. MSC Cruises shore excursions can be a clever option to see much of Ho Chi Minh City’s fun that derives from the simple pleasure of absorbing its flurry of activity – something best done from the seat of a cyclo or a roadside café. To blink is to miss some new and singular sight, be it a motorbike stacked high with piglets bound for the market, or a boy on a bicycle rapping out a staccato tattoo on pieces of bamboo to advertise noodles for sale. For some visitors, the American war is their primary frame of reference and such historical hot spots as the Reunification Palace rank highly on their itineraries. In addition, ostentatious reminders of French rule abound, among them such memorable buildings as Notre Dame Cathedral and the grandiose Hotel de Ville – but even these look spanking-new when compared to gloriously musty edifices like Quan Am Pagoda and the Jade Emperor Pagoda, just a couple of the many captivating places of worship across the city. And don’t miss Ben Thanh Market, the teeming Vietnamese market par excellence, check the city’s pulse here on an early morning stroll. Ho Chi Minh City port guide Search cruises visiting Ho Chi Minh City

Ho Chi Minh City photo — Day 12 Nov 10, 2026 Ho Chi Minh City Ho Chi Minh City is a vibrant port of call for MSC cruise liners on MSC Grand Voyages cruise itineraries. It’s a fury of sights and sounds, and the crucible in which Vietnam’s rallying fortunes are boiling. Few corners of the city afford respite from the cacophony of construction work casting up new office blocks and hotels with logic-defying speed. An increasing number of cars and minibuses jostle with an organic mass of state-of-the-art Honda SUVs, choking the tree-lined streets and boulevards. Amid this melee, the local people go about their daily life: smartly dressed schoolkids wander past streetside baguette-sellers; women shoppers ride motorbikes clad in gangster-style bandanas to protect their skin from the sun and dust; while teenagers in designer jeans chirrup into mobile phones. MSC Cruises shore excursions can be a clever option to see much of Ho Chi Minh City’s fun that derives from the simple pleasure of absorbing its flurry of activity – something best done from the seat of a cyclo or a roadside café. To blink is to miss some new and singular sight, be it a motorbike stacked high with piglets bound for the market, or a boy on a bicycle rapping out a staccato tattoo on pieces of bamboo to advertise noodles for sale. For some visitors, the American war is their primary frame of reference and such historical hot spots as the Reunification Palace rank highly on their itineraries. In addition, ostentatious reminders of French rule abound, among them such memorable buildings as Notre Dame Cathedral and the grandiose Hotel de Ville – but even these look spanking-new when compared to gloriously musty edifices like Quan Am Pagoda and the Jade Emperor Pagoda, just a couple of the many captivating places of worship across the city. And don’t miss Ben Thanh Market, the teeming Vietnamese market par excellence, check the city’s pulse here on an early morning stroll. Ho Chi Minh City port guide Search cruises visiting Ho Chi Minh City

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Show all 8 cabin grades

Cabin grades and pricing
Name	Supplier code	Type
Deluxe Twin Balcony Suite	A	Suite
Angkor Suite	ANG	Suite
Deluxe Twin Balcony Suite	B	Suite
Bayon Suites	BAY	Suite
Deluxe Twin Balcony Suite	C	Suite
Deluxe Twin Balcony Suite	D	Suite
Deluxe Twin Balcony Suite	E	Suite
Deluxe Twin Balcony Suite	EE	Suite