MSC Grand Voyages from Genoa (Portofino)

The MSC Grand Voyages from Genoa (Portofino) is a 16-night South America cruise aboard MSC Musica, operated by MSC Cruises. Departing Genoa, Italy on October 27, 2026, the voyage visits 8 ports.

Length: 16 nights
Departs: Oct 27, 2026
Returns: Nov 12, 2026
Ports of call: 8
Days at sea: 9

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Itinerary

Day 1 Oct 27, 2026 Genoa, Italy Departs 17:00 Genoa is marvellously eclectic, vibrant and full of rough-edged style; it’s a great cruise excursion. Indeed “La Superba” (The Superb), as it was known at the height of its authority as a Mediterranean superpower, boasts more zest and intrigue than all the surrounding coastal resorts put together. During a holiday to Genoa you can explore its old town: a dense and fascinating warren of medieval alleyways home to large palazzi built in the sixteenth and seventeenth centuries by Genoa’s wealthy mercantile families and now transformed into museums and art galleries. You should seek out the Cattedrale di San Lorenzo, the Palazzo Ducale, and the Renaissance palaces of Via Garibaldi which contain the cream of Genoa’s art collections, as well as furniture and decor from the grandest days of the city’s past, when its ships sailed to all corners of the Mediterranean Sea. The Acquario di Genova is the city’s pride and joy, parked like a giant ocean liner on the waterfront, with seventy tanks housing sea creatures from all the world’s major habitats, including the world’s biggest reconstruction of a Caribbean coral reef. It’s a great aquarium by any standards, the second largest in Europe by capacity, and boasts a fashionably ecology-conscious slant and excellent background information in Italian and English. Just 35 km south of Genoa, there’s no denying the appeal of Portofino, tucked into a protected inlet surrounded by lush cypress- and olive-clad slopes. It’s an A-list resort that has been attracting high-flying bankers, celebs and their hangers-on for years, as evidenced by the flotillas of giant yachts usually anchored just outside. It’s a tiny place that is attractive yet somehow off-putting at the same time, with a quota of fancy shops, bars and restaurants for a place twice its size. Genoa, Italy port guide Search cruises visiting Genoa, Italy

Genoa, Italy photo — Day 1 Oct 27, 2026 Genoa, Italy Departs 17:00 Genoa is marvellously eclectic, vibrant and full of rough-edged style; it’s a great cruise excursion. Indeed “La Superba” (The Superb), as it was known at the height of its authority as a Mediterranean superpower, boasts more zest and intrigue than all the surrounding coastal resorts put together. During a holiday to Genoa you can explore its old town: a dense and fascinating warren of medieval alleyways home to large palazzi built in the sixteenth and seventeenth centuries by Genoa’s wealthy mercantile families and now transformed into museums and art galleries. You should seek out the Cattedrale di San Lorenzo, the Palazzo Ducale, and the Renaissance palaces of Via Garibaldi which contain the cream of Genoa’s art collections, as well as furniture and decor from the grandest days of the city’s past, when its ships sailed to all corners of the Mediterranean Sea. The Acquario di Genova is the city’s pride and joy, parked like a giant ocean liner on the waterfront, with seventy tanks housing sea creatures from all the world’s major habitats, including the world’s biggest reconstruction of a Caribbean coral reef. It’s a great aquarium by any standards, the second largest in Europe by capacity, and boasts a fashionably ecology-conscious slant and excellent background information in Italian and English. Just 35 km south of Genoa, there’s no denying the appeal of Portofino, tucked into a protected inlet surrounded by lush cypress- and olive-clad slopes. It’s an A-list resort that has been attracting high-flying bankers, celebs and their hangers-on for years, as evidenced by the flotillas of giant yachts usually anchored just outside. It’s a tiny place that is attractive yet somehow off-putting at the same time, with a quota of fancy shops, bars and restaurants for a place twice its size. Genoa, Italy port guide Search cruises visiting Genoa, Italy

Day 2 Oct 28, 2026 Marseille, France 08:00 – 18:00 10.0 hrs ashore Marseille is the second largest city in France after Paris. It is also one of the oldest continuously inhabited cities in the Mediterranean. Cave paintings in the nearby Calanques are estimated to be 30,000 years old, and remains of brick habitations date from 6,000 BCE. The more recent history begins with a Hellenic port in about 600 BCE, some remains of which are on view at the city’s History Museum. It has been one of the world’s major seaports almost from its founding, and served as the main European terminus of the French colonial empire in Africa and the Far East. It is located in the Provence-Alpes-Cote d’Azur region and is the capital of the Bouches-du-Rhone department. On an island in the expansive bay of Marseille stands the prison of Chateau d’If made famous by the Alexandre Dumas novel “The Count of Monte Cristo.” The Vieux-Port with its atmospheric buildings and wharves is the area where visitors can search for the perfect example of the local specialty bouillabaisse, a rich fish stew containing at least three, and often more varieties of local fishes. Marseille’s newly renovated port at the venerable Joliette Docks is situated very close to the striking Cathédrale de la Major and the fascinating collections at the Museum of African, Oceanic and American Indian Arts. Marseille, France port guide Search cruises visiting Marseille, France

Marseille, France photo — Day 2 Oct 28, 2026 Marseille, France 08:00 – 18:00 10.0 hrs ashore Marseille is the second largest city in France after Paris. It is also one of the oldest continuously inhabited cities in the Mediterranean. Cave paintings in the nearby Calanques are estimated to be 30,000 years old, and remains of brick habitations date from 6,000 BCE. The more recent history begins with a Hellenic port in about 600 BCE, some remains of which are on view at the city’s History Museum. It has been one of the world’s major seaports almost from its founding, and served as the main European terminus of the French colonial empire in Africa and the Far East. It is located in the Provence-Alpes-Cote d’Azur region and is the capital of the Bouches-du-Rhone department. On an island in the expansive bay of Marseille stands the prison of Chateau d’If made famous by the Alexandre Dumas novel “The Count of Monte Cristo.” The Vieux-Port with its atmospheric buildings and wharves is the area where visitors can search for the perfect example of the local specialty bouillabaisse, a rich fish stew containing at least three, and often more varieties of local fishes. Marseille’s newly renovated port at the venerable Joliette Docks is situated very close to the striking Cathédrale de la Major and the fascinating collections at the Museum of African, Oceanic and American Indian Arts. Marseille, France port guide Search cruises visiting Marseille, France

Day 3 Oct 29, 2026 Tarragona 08:00 – 18:00 10.0 hrs ashore Tarragona, port city of Spain, is located less than 100 km from Barcelona from the top of its walls, here you can admire one of the most important Gothic cathedrals in Catalonia and the immense amphitheatre, stage for gladiatorial combat in Roman times. During your Mediterranean cruise, you will visit the Port of Tarragona; a true gem, with Roman ruins that are the pride of its residents and historical traditions that are part of the local folklore. The Roman heritage is still part of the urban context in Tarragona. Here, you can watch the reenactments of the centurion parades and gladiatorial combat. During the stop in the port of Tarragona, proceed to the Praetorian Tower. On the first floor there is a model of the medieval town and its glory that was lost during a war that is still commemorated with solemn candles on the steps of the cathedral. If you have the time, watch the races of human pyramids that are organised in various districts of the city. Tarragona port guide Search cruises visiting Tarragona

Tarragona photo — Day 3 Oct 29, 2026 Tarragona 08:00 – 18:00 10.0 hrs ashore Tarragona, port city of Spain, is located less than 100 km from Barcelona from the top of its walls, here you can admire one of the most important Gothic cathedrals in Catalonia and the immense amphitheatre, stage for gladiatorial combat in Roman times. During your Mediterranean cruise, you will visit the Port of Tarragona; a true gem, with Roman ruins that are the pride of its residents and historical traditions that are part of the local folklore. The Roman heritage is still part of the urban context in Tarragona. Here, you can watch the reenactments of the centurion parades and gladiatorial combat. During the stop in the port of Tarragona, proceed to the Praetorian Tower. On the first floor there is a model of the medieval town and its glory that was lost during a war that is still commemorated with solemn candles on the steps of the cathedral. If you have the time, watch the races of human pyramids that are organised in various districts of the city. Tarragona port guide Search cruises visiting Tarragona

Day 5 Oct 31, 2026 Casablanca 08:00 – 23:00 15.0 hrs ashore Immortal lines from the silver screen may have imprinted a warm, fuzzy visage of old Casablanca into our minds, but this thriving city is a curious example of what Morocco’s modernity looks like. Glistening white art deco buildings line the wide pathways that sweep through Casablanca, as the sea sparkles like a thin mirage on the horizon. There’s an aura of creativity amid Casablanca’s culture and chaos, helping to make the city one of Morocco’s most curious and compelling. The Hassan II Mosque took a staggering seven years and 10,000 artists to craft its legacy as the country's largest mosque, and to bring the world's tallest minaret to sky-high reality. A vision of cool to the touch marble, cavernous prayer rooms and intricate inlays, the mosque is extraordinary in scale and ambition. Retractable roofs let the sun flood in, while dizzying glass floors dazzle, and the blue Atlantic waves surge below your feet. After that humbling visit, stroll along La Corniche - where surfers glide across rough and tumble waves, and chic cafes offer front-row seats for sweet peppermint teas with a side of people-watching. Casablanca is a diner's city - boulevards laced with French-fusion restaurants, buzzy beachfront joints, and raw seafood bars provide gem-like offerings fresh from the boat. Those seeking a slice of that golden-age Hollywood romance can wander through the medina, with its unabashed ramshackle feel, and maze of alleyways punctuated with busy barber shops and butchers. Casablanca port guide Search cruises visiting Casablanca

Casablanca photo — Day 5 Oct 31, 2026 Casablanca 08:00 – 23:00 15.0 hrs ashore Immortal lines from the silver screen may have imprinted a warm, fuzzy visage of old Casablanca into our minds, but this thriving city is a curious example of what Morocco’s modernity looks like. Glistening white art deco buildings line the wide pathways that sweep through Casablanca, as the sea sparkles like a thin mirage on the horizon. There’s an aura of creativity amid Casablanca’s culture and chaos, helping to make the city one of Morocco’s most curious and compelling. The Hassan II Mosque took a staggering seven years and 10,000 artists to craft its legacy as the country's largest mosque, and to bring the world's tallest minaret to sky-high reality. A vision of cool to the touch marble, cavernous prayer rooms and intricate inlays, the mosque is extraordinary in scale and ambition. Retractable roofs let the sun flood in, while dizzying glass floors dazzle, and the blue Atlantic waves surge below your feet. After that humbling visit, stroll along La Corniche - where surfers glide across rough and tumble waves, and chic cafes offer front-row seats for sweet peppermint teas with a side of people-watching. Casablanca is a diner's city - boulevards laced with French-fusion restaurants, buzzy beachfront joints, and raw seafood bars provide gem-like offerings fresh from the boat. Those seeking a slice of that golden-age Hollywood romance can wander through the medina, with its unabashed ramshackle feel, and maze of alleyways punctuated with busy barber shops and butchers. Casablanca port guide Search cruises visiting Casablanca

Day 7 Nov 2, 2026 Santa Cruz de Tenerife 09:00 – 18:00 9.0 hrs ashore The old town is a treasury of 16th and 17th century buildings, and not just churches. Do go inside the fortified-looking Iglesia del Salvador, however, to see its ornate, Islamic-style Mudejar ceiling, one of the best in the islands. A short way outside town is the Sanctuary of the Virgin of the Snows, one of the most important sites on the island. The waterfront is a good place to find ancient houses with elaborate iron balconies, many now converted to restaurants and shops. Many visitors tour the island’s dormant volcanoes, or the odd, erosion caldera called La Cumbrecita, a UNESCO Biosphere Site. An excursion to the village of Mazo rewards with a fine island museum containing examples of local handicrafts and especially the fabulous indigenous embroidery. Just beyond the museum is a handicrafts school, an excellent place to acquire a handcrafted souvenir of your Canary Islands adventure. Santa Cruz de Tenerife port guide Search cruises visiting Santa Cruz de Tenerife

Santa Cruz de Tenerife photo — Day 7 Nov 2, 2026 Santa Cruz de Tenerife 09:00 – 18:00 9.0 hrs ashore The old town is a treasury of 16th and 17th century buildings, and not just churches. Do go inside the fortified-looking Iglesia del Salvador, however, to see its ornate, Islamic-style Mudejar ceiling, one of the best in the islands. A short way outside town is the Sanctuary of the Virgin of the Snows, one of the most important sites on the island. The waterfront is a good place to find ancient houses with elaborate iron balconies, many now converted to restaurants and shops. Many visitors tour the island’s dormant volcanoes, or the odd, erosion caldera called La Cumbrecita, a UNESCO Biosphere Site. An excursion to the village of Mazo rewards with a fine island museum containing examples of local handicrafts and especially the fabulous indigenous embroidery. Just beyond the museum is a handicrafts school, an excellent place to acquire a handcrafted souvenir of your Canary Islands adventure. Santa Cruz de Tenerife port guide Search cruises visiting Santa Cruz de Tenerife

Day 14 Nov 9, 2026 Salvador 11:00 – 18:00 7.0 hrs ashore High above the enormous bay of Todos os Santos (All Saints), where your MSC cruise ship awaits your return, Salvador de Bahia has an electric feel from the moment you arrive. This is the great cultural and historical centre of Brazil, where Afro-Brazilian heritage is strongest and where capoeira, candomblé and samba de roda were created. MSC South America cruises offer excursions to the centro histórico of this magical place, a melange of narrow cobbled streets, peeling purple walls, grand Baroque churches, kids kicking footballs, rastas, locals sipping bottled beer on plastic chairs, the wafting aroma of herbs and the almost constant beating of drums, especially as the sun sets. Beyond the old town Salvador is a vast, sprawling city, with a vibrant beach life, modern skyscrapers and plenty of favelas. The centro histórico is the traditional heart of Salvador; it’s built around the craggy, 70m-high bluff that dominates the eastern side of the bay, and is split into upper and lower sections. Cidade Alta (or simply “Centro”) is strung along its top, linked to the less interesting Cidade Baixa (the old commercial centre, aka “Comércio”) by precipitous streets and the towering Art Deco lift-shaft of the Elevador Lacerda. Cidade Alta is the cultural centre of the city, and the section known as the Pelourinho is the groovy old district with colourful and hilly winding streets, its most vibrant and beguiling neighbourhood. The best spot to begin a walking tour of the city is at the Praça Municipal, the square dominated by the impressive Palácio do Rio Branco, the old governor’s palace which was in use until 1979. The fine interior is a blend of Rococo plasterwork, polished wooden floors and painted walls and ceilings. Salvador port guide Search cruises visiting Salvador

Salvador photo — Day 14 Nov 9, 2026 Salvador 11:00 – 18:00 7.0 hrs ashore High above the enormous bay of Todos os Santos (All Saints), where your MSC cruise ship awaits your return, Salvador de Bahia has an electric feel from the moment you arrive. This is the great cultural and historical centre of Brazil, where Afro-Brazilian heritage is strongest and where capoeira, candomblé and samba de roda were created. MSC South America cruises offer excursions to the centro histórico of this magical place, a melange of narrow cobbled streets, peeling purple walls, grand Baroque churches, kids kicking footballs, rastas, locals sipping bottled beer on plastic chairs, the wafting aroma of herbs and the almost constant beating of drums, especially as the sun sets. Beyond the old town Salvador is a vast, sprawling city, with a vibrant beach life, modern skyscrapers and plenty of favelas. The centro histórico is the traditional heart of Salvador; it’s built around the craggy, 70m-high bluff that dominates the eastern side of the bay, and is split into upper and lower sections. Cidade Alta (or simply “Centro”) is strung along its top, linked to the less interesting Cidade Baixa (the old commercial centre, aka “Comércio”) by precipitous streets and the towering Art Deco lift-shaft of the Elevador Lacerda. Cidade Alta is the cultural centre of the city, and the section known as the Pelourinho is the groovy old district with colourful and hilly winding streets, its most vibrant and beguiling neighbourhood. The best spot to begin a walking tour of the city is at the Praça Municipal, the square dominated by the impressive Palácio do Rio Branco, the old governor’s palace which was in use until 1979. The fine interior is a blend of Rococo plasterwork, polished wooden floors and painted walls and ceilings. Salvador port guide Search cruises visiting Salvador

Day 16 Nov 11, 2026 Rio de Janeiro 09:00 – 18:00 9.0 hrs ashore As you’ll be able to appreciate when you cruise the Atlantic Ocean with MSC Cruises, in its position on the southern shore of the magnificent Guanabara Bay, Rio de Janeiro has, without a shadow of a doubt, one of the most stunning settings in the world. Extending for 20km along an alluvial strip, between an azure sea and forest-clad mountains, the city’s streets and buildings have been moulded around the foothills of the mountain range that provides its backdrop, while out in the bay there are many rocky islands fringed with white sand. The aerial views over Rio are breathtaking, and even the concrete skyscrapers that dominate the city’s skyline add to the attraction. As the former capital of Brazil and now its second-largest city, Rio has a remarkable architectural heritage, some of the country’s best museums and galleries, superb restaurants and a vibrant nightlife – in addition to its legendary beaches. A shore excursion on your MSC South America cruise can be the opportunity to visit the Pão de Açúcar. The Sugar Loaf Mountain rises where Guanabara Bay meets the Atlantic Ocean. Its name may simply reflect a resemblance to the moulded loaves in which sugar was once commonly sold. Alternatively, it may be a corruption of the indigenous Tamoya word Pau-nh-Açuquá, meaning “high, pointed or isolated hill”. On the top of Corcoavado Mountain instead the Art Deco statue of Cristo Redentor (Christ the Redeemer), arms outstretched in welcome, stands 30m high and weighs over 1000 tonnes. It was supposed to be completed for Brazil’s centenary independence celebrations in 1922, but wasn’t actually finished until 1931. In clear weather, fear no anticlimax: climbing to the statue is a stunning experience, with the whole of Rio and Guanabara Bay laid out before you. Rio de Janeiro port guide Search cruises visiting Rio de Janeiro

Rio de Janeiro photo — Day 16 Nov 11, 2026 Rio de Janeiro 09:00 – 18:00 9.0 hrs ashore As you’ll be able to appreciate when you cruise the Atlantic Ocean with MSC Cruises, in its position on the southern shore of the magnificent Guanabara Bay, Rio de Janeiro has, without a shadow of a doubt, one of the most stunning settings in the world. Extending for 20km along an alluvial strip, between an azure sea and forest-clad mountains, the city’s streets and buildings have been moulded around the foothills of the mountain range that provides its backdrop, while out in the bay there are many rocky islands fringed with white sand. The aerial views over Rio are breathtaking, and even the concrete skyscrapers that dominate the city’s skyline add to the attraction. As the former capital of Brazil and now its second-largest city, Rio has a remarkable architectural heritage, some of the country’s best museums and galleries, superb restaurants and a vibrant nightlife – in addition to its legendary beaches. A shore excursion on your MSC South America cruise can be the opportunity to visit the Pão de Açúcar. The Sugar Loaf Mountain rises where Guanabara Bay meets the Atlantic Ocean. Its name may simply reflect a resemblance to the moulded loaves in which sugar was once commonly sold. Alternatively, it may be a corruption of the indigenous Tamoya word Pau-nh-Açuquá, meaning “high, pointed or isolated hill”. On the top of Corcoavado Mountain instead the Art Deco statue of Cristo Redentor (Christ the Redeemer), arms outstretched in welcome, stands 30m high and weighs over 1000 tonnes. It was supposed to be completed for Brazil’s centenary independence celebrations in 1922, but wasn’t actually finished until 1931. In clear weather, fear no anticlimax: climbing to the statue is a stunning experience, with the whole of Rio and Guanabara Bay laid out before you. Rio de Janeiro port guide Search cruises visiting Rio de Janeiro

Day 17 Nov 12, 2026 Santos, Brazil Arrives 08:00 Santos, one of Portugal’s first New World settlements, was founded in 1535. Today your MSC ship will be docking in Latin America’s largest port, through which passes a large proportion of the world’s coffee, sugar and oranges. The city stands partly on São Vicente island, its docking facilities and old town facing landwards, with ships approaching by a narrow, but deep, channel. Its compact centre retains a certain charm that’s massively popular with local tourists, and there is a good deal of historical and maritime interest around the city. On an MSC South America cruise excursion to the city centre you’ll find the ruins of some of Santos’s most distinguished buildings along Rua do Comércio. Although sometimes only the facades remain, some of the nineteenth-century former merchants’ houses that line the street are gradually being restored, the elaborate tiling and wrought-iron balconies offering a hint of the old town’s lost grandeur. MSC South America cruises also offer excursions to the local Santos Futebol Clube. It’s best known as the club for which the great Pelé played for most of his professional life (from 1956 to 1974); their stadium, the Vila Belmiro, is open to the public when there’s no game on. In addition to honouring Pelé at the club’s small museum, you can take an hour-long guided tour including the players’ bar and dressing rooms. Santos’s beaches are across town from Centro on the south side of the island. The beaches are huge, stretching around the Atlantic-facing Baía de Santos, and popular in summer. Santos, Brazil port guide Search cruises visiting Santos, Brazil

Santos, Brazil photo — Day 17 Nov 12, 2026 Santos, Brazil Arrives 08:00 Santos, one of Portugal’s first New World settlements, was founded in 1535. Today your MSC ship will be docking in Latin America’s largest port, through which passes a large proportion of the world’s coffee, sugar and oranges. The city stands partly on São Vicente island, its docking facilities and old town facing landwards, with ships approaching by a narrow, but deep, channel. Its compact centre retains a certain charm that’s massively popular with local tourists, and there is a good deal of historical and maritime interest around the city. On an MSC South America cruise excursion to the city centre you’ll find the ruins of some of Santos’s most distinguished buildings along Rua do Comércio. Although sometimes only the facades remain, some of the nineteenth-century former merchants’ houses that line the street are gradually being restored, the elaborate tiling and wrought-iron balconies offering a hint of the old town’s lost grandeur. MSC South America cruises also offer excursions to the local Santos Futebol Clube. It’s best known as the club for which the great Pelé played for most of his professional life (from 1956 to 1974); their stadium, the Vila Belmiro, is open to the public when there’s no game on. In addition to honouring Pelé at the club’s small museum, you can take an hour-long guided tour including the players’ bar and dressing rooms. Santos’s beaches are across town from Centro on the south side of the island. The beaches are huge, stretching around the Atlantic-facing Baía de Santos, and popular in summer. Santos, Brazil port guide Search cruises visiting Santos, Brazil

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Show all 16 cabin grades

Cabin grades and pricing
Name	Supplier code	Type
BALCONY AUREA	BA	Balcony
BALCONY BELLA GUARANTEED	BB	Balcony
PREMIUM BALCONY FANTASTICA	BL1	Balcony
PREMIUM BALCONY FANTASTICA	BL2	Balcony
DELUXE BALCONY WITH PARTIAL VIEW FANTASTICA	BP	Balcony
DELUXE BALCONY FANTASTICA	BR1	Balcony
DELUXE BALCONY FANTASTICA	BR2	Balcony
INTERIOR BELLA GUARANTEED	IB	Inside
DELUXE INTERIOR FANTASTICA	IR1	Inside
DELUXE INTERIOR FANTASTICA	IR2	Inside
Inside Cabin	SPL	Inside
OCEAN VIEW BELLA GUARANTEED	OB	Oceanview
DELUXE OCEAN VIEW WITH OBSTRUCTED VIEW FANTASTICA	OO	Oceanview
DELUXE OCEAN VIEW FANTASTICA	OR1	Oceanview
DELUXE OCEAN VIEW FANTASTICA	OR2	Oceanview
PREMIUM SUITE AUREA	SL1	Suite