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13-night South America cruise: Lima, Peru to Guayaquil on MS Santa Cruz II

The Galápagos Islands – In Darwin’s Footsteps Plus Machu Picchu is a 13-night South America cruise aboard MS Santa Cruz II, operated by HX Expeditions. Departing Lima, Peru on March 3, 2028 and arriving in Guayaquil on March 16, 2028, the voyage visits 9 ports including Cusco/Lima, Machu Picchu, Quito. Fares start from $13,251 per person.

Length
13 nights
Departs
Mar 3, 2028
Returns
Mar 16, 2028
Ports of call
9

Voyage code _@SCGALEMACEU-280303

Lima, Peru

13 nights · South America

from $13,251 pp

via CruiseDirect

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Why this route stands out

A closer look at the journey

Lima, Peru

Splashing colour and culture into the arid Peruvian landscape, Lima is a city bedecked with grand colonial splendour. Founded in 1535, this sprawling capital enjoys a breezy oceanfront location and forms one of the world's largest desert cities. A place of sharp contrasts, almost 10 million people are packed into the city, occupying vastly different living conditions. Visit for an unfiltered experience of this richly layered place of ancient history, colonial relics and dazzling flavours. View less Rising from the misty blanket of the garua - a persistent fog that cloaks Lima during winter - you'll find one of South America's most culturally vibrant cities. The former capital of the Spanish colonists - head to Plaza de Armas to immerse yourself in the heart of the old city. The Basilica Cathedral of Lima watches over Plaza Mayor - listen out for the stomps of boots outside, as the pomp and ceremony of the Changing of the Guards draws crowds to the Government Palace. The history of this area runs much deeper, however, and pre-Colombian cities and temples emerge from the dusty earth nearby. Grand museums showcase unearthed treasures from the extraordinary civilisations who built vast mud adobe cities across Peru's coastline, and incredible settlements in the country's valleys and mountains. The Barranco district is Lima's artsy area, and you can walk from modern art galleries to see the local muse, the Bridge of Sighs. This wooden bridge is an artist's favourite, and one of the city's most romantic spots. Afterwards, sample some of Lima's cuisine, and the zingy flavours of spicy, lime-marinated fish ceviche. So revered in these parts, ceviche even has its own national day on June 28th. Sipping a Pisco Sour is the perfect way to round off your visit to this engrossing, multi-layered city.

Cusco/Lima

Cusco, a city in the Peruvian Andes, was once capital of the Inca Empire, and is now known for its archaeological remains and Spanish colonial architecture. Plaza de Armas is the central square in the old city, with arcades, carved wooden balconies and Incan wall ruins. The baroque Santo Domingo Convent was built on top of the Incan Temple of the Sun (Qoricancha), and has archaeological remains of Inca stonework.

Quito

Quito, Ecuador's capital, sits high in the Andean foothills at an altitude of 2,850m. Constructed on the foundations of an ancient Incan city, it’s known for its well-preserved colonial center, rich with 16th- and 17th-century churches and other structures blending European, Moorish and indigenous styles. These include the cathedral, in the Plaza Grande square, and ultra-ornate Compañia de Jesús Jesuit church.

Price tracking

Today’s fare, in context

Price history

Cheaper than 44%
30 days
Fare details

Fare details

Per person · taxes & fees included
Current fares
Verified 14 hours ago
Oceanview
$13,251
Suite
$15,977
Tracked range
69 days
Price history by cabin type
CabinCurrentLowestHighest
Oceanview $13,251 $13,250 on Jun 25 $13,251 on Jul 24
Suite $15,977 $15,976 on Jun 25 $15,977 on Jul 24
Cabin grades
6 total
Explorer CabinOceanview · EE
Explorer CabinOceanview · EH
Explorer CabinOceanview · EP
Explorer Family CabinOceanview · FH
Voyager Single CabinOceanview · VH
Darwin SuiteSuite · DS

○ = last seen (sold out or delisted). · Verified 14 hours ago.

Lowest fares with no residency, age, or service requirement — verify eligibility at booking. How our pricing works

Current prices

Per person · 2 guests · incl. taxes & fees

Inside

Not available

Oceanview

from $13,251

$1,019 / night

Fare rows

Explorer Cabin

Cabin grade

Available

from $13,251

$1,019 / night

per person · incl. taxes & fees

Explorer Cabin

Cabin grade

Available

from $13,685

$1,052 / night

per person · incl. taxes & fees

Explorer Cabin

Cabin grade

Available

from $14,118

$1,086 / night

per person · incl. taxes & fees

Explorer Family Cabin

Cabin grade

Available

from $14,118

$1,086 / night

per person · incl. taxes & fees

Voyager Single Cabin

Cabin grade

Available

from $14,769

$1,136 / night

per person · incl. taxes & fees

Balcony

Not available

Suite

from $15,977

$1,229 / night

Fare rows

Darwin Suite

Cabin grade

Available

from $15,977

$1,229 / night

per person · incl. taxes & fees

Prices verified Sep 1, 2026

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The journey

13 nights, in order

Lima, Peru

Day 1 Mar 3, 2028

Lima, Peru

Splashing colour and culture into the arid Peruvian landscape, Lima is a city bedecked with grand colonial splendour.

Explore Lima, Peru

Day by day

The full itinerary

14 scheduled calls
MS Santa Cruz II

Your ship

MS Santa Cruz II

With carbon-neutral operations, MS Santa Cruz II is environmentally-sustainable and socially conscious with the local community. This sleek, spacious ship has a layout that allows you to enjoy your cruise from start to finish. Enjoy delicious food in the elegant restaurant, increase your knowledge of the Galápagos Islands with your fellow travellers in the Science Center or maybe mingle out on the multiple decks. While exploring the Galápagos, you'll have the ability to actively engage in activities and encounters. After a day in Darwin's footsteps, you will enjoy coming home to a casual atmosphere with the best service there is. MS Santa Cruz II's amenities easily appeal to all world explorers.

4★ 2,664 GT 90 Passengers Built 2021
MS Santa Cruz II ship guide Search cruises on MS Santa Cruz II

Deck plans

Deck plan for Deck 1

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from $13,251 pp

via CruiseDirect

Book with CruiseDirect

Book direct with HX Expeditions we may earn a commission