16-night Mediterranean cruise: Genoa, Italy to Santos, Brazil on MSC Divina
The 16 nights South America from Genoa (Portofino) is a 16-night Mediterranean cruise aboard MSC Divina, operated by MSC Cruises. Departing Genoa, Italy on October 31, 2026 and arriving in Sao Paulo on November 16, 2026, the voyage visits 6 ports including Tarragona, Santa Cruz de Tenerife, Salvador. Fares start from $1,098 per person.
Fixed editorial images from the places on this itinerary. They stay stable each time you return to this sailing.
Genoa, Italy
Genoa is marvellously eclectic, vibrant and full of rough-edged style; it’s a great cruise excursion.
Indeed “La Superba” (The Superb), as it was known at the height of its authority as a Mediterranean superpower, boasts more zest and intrigue than all the surrounding coastal resorts put together.
During a holiday to Genoa you can explore its old town: a dense and fascinating warren of medieval alleyways home to large palazzi built in the sixteenth and seventeenth centuries by Genoa’s wealthy mercantile families and now transformed into museums and art galleries. You should seek out the Cattedrale di San Lorenzo, the Palazzo Ducale, and the Renaissance palaces of Via Garibaldi which contain the cream of Genoa’s art collections, as well as furniture and decor from the grandest days of the city’s past, when its ships sailed to all corners of the Mediterranean Sea.
The Acquario di Genova is the city’s pride and joy, parked like a giant ocean liner on the waterfront, with seventy tanks housing sea creatures from all the world’s major habitats, including the world’s biggest reconstruction of a Caribbean coral reef. It’s a great aquarium by any standards, the second largest in Europe by capacity, and boasts a fashionably ecology-conscious slant and excellent background information in Italian and English.
Just 35 km south of Genoa, there’s no denying the appeal of Portofino, tucked into a protected inlet surrounded by lush cypress- and olive-clad slopes. It’s an A-list resort that has been attracting high-flying bankers, celebs and their hangers-on for years, as evidenced by the flotillas of giant yachts usually anchored just outside. It’s a tiny place that is attractive yet somehow off-putting at the same time, with a quota of fancy shops, bars and restaurants for a place twice its size.
Tarragona
Tarragona, port city of Spain, is located less than 100 km from Barcelona from the top of its walls, here you can admire one of the most important Gothic cathedrals in Catalonia and the immense amphitheatre, stage for gladiatorial combat in Roman times.
During your Mediterranean cruise, you will visit the Port of Tarragona; a true gem, with Roman ruins that are the pride of its residents and historical traditions that are part of the local folklore.
The Roman heritage is still part of the urban context in Tarragona. Here, you can watch the reenactments of the centurion parades and gladiatorial combat. During the stop in the port of Tarragona, proceed to the Praetorian Tower. On the first floor there is a model of the medieval town and its glory that was lost during a war that is still commemorated with solemn candles on the steps of the cathedral. If you have the time, watch the races of human pyramids that are organised in various districts of the city.
Santa Cruz de Tenerife
The old town is a treasury of 16th and 17th century buildings, and not just churches. Do go inside the fortified-looking Iglesia del Salvador, however, to see its ornate, Islamic-style Mudejar ceiling, one of the best in the islands. A short way outside town is the Sanctuary of the Virgin of the Snows, one of the most important sites on the island. The waterfront is a good place to find ancient houses with elaborate iron balconies, many now converted to restaurants and shops. Many visitors tour the island’s dormant volcanoes, or the odd, erosion caldera called La Cumbrecita, a UNESCO Biosphere Site. An excursion to the village of Mazo rewards with a fine island museum containing examples of local handicrafts and especially the fabulous indigenous embroidery. Just beyond the museum is a handicrafts school, an excellent place to acquire a handcrafted souvenir of your Canary Islands adventure.
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MSC Divina is home to a variety of sports, leisure facilities and world-class entertainment, including Kids and Teen Clubs to ensure that everyone makes the most of their time on board. Inspired by Sophia Loren, the ship is stylish, luxurious and elegant, bringing you all the glitz and glamour of the golden age of cruise.
MSC Divina boasts a real stone piazza, a Casino Veneziano and Broadway-style Pantheon Theatre. From the elegant Swarovski crystal staircases to the breathtaking Infinity Pool at the back of the ship, the ship is undeniably glamorous.
Discover the exclusive ship-within-a-ship on board MSC Divina that is MSC Yacht Club with its 24-hour Butler service and Concierge. There is even a Sophia Loren Royal Suite on deck 16, designed with the help of the screen siren herself. The suite includes stunning photographs of Ms Loren’s most memorable roles and even a replica of her dressing table so that guests can prepare themselves in style.
A wealth of wellness treatments await in the relaxing atmosphere of the MSC Aurea Spa. Or why not relax outside on the sun-drenched, adult-only Top 18 sun-deck with stunning sea views, a dedicated spa service and a bar menu with complimentary fruit skewers.
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