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10-night Europe cruise: Istanbul to Civitavecchia, Rome on Sirena

The Istanbul to Rome is a 10-night Europe cruise aboard Sirena, operated by Oceania Cruises. Departing Istanbul on July 9, 2027 and arriving in Civitavecchia, Rome on July 19, 2027, the voyage visits 11 ports including Mitilini (Lesvos), Kavala, Greece, Thessaloniki. Fares start from $2,250 per person.

Length
10 nights
Departs
Jul 9, 2027
Returns
Jul 19, 2027
Ports of call
11

Voyage code SIR270709

Istanbul

10 nights · Europe

from $2,250 pp

via CruiseDirect

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Why this route stands out

A closer look at the journey

Istanbul

A shore excursion on your MSC Mediterranean cruise can be the opportunity to discover İstanbul which stands astride two continents, Europe and Asia. As if its spectacular geographical location were not enough, it can also boast of being the only city to have played capital to consecutive Christian and Islamic empires, a role that has shaped the region’s history for more than 2500 years and bequeathed to İstanbul a staggering wealth of attractions. Most cruise visitors spend all their holiday time in Sultanahmet, home to İstanbul’s main sightseeing attractions: the church of Aya Sofya, the greatest legacy of the Byzantine Empire; the Topkapı Palace, heart of the Ottoman Empire; and the massive Sultanahmet Camii (Blue Mosque). Here also are the ancient Hippodrome, the Museum of Turkish and Islamic Art (housed in the former Palace of İbrahim Paşa), the eerily lit Yerebatan Sarnıcı, a fascinating Byzantine underground cistern, and the Grand Bazaar (Kapalı Çarşı), the largest covered bazaar in the world. The monumental architecture, attractive parks and gardens, street-side cafés, and the benefits of a relatively traffic-free main road combine to make this area pleasant for both sightseeing and staying on an MSC Mediterranean cruise excursion. İstanbul’s Ottoman-era Grand Bazaar gets more than its fair share of souvenir-hungry visitors. The area around it, however, is relatively little explored, which is a shame as it holds some very worthwhile attractions, from the historic Cembirlitaş Hamamı, one of the best Turkish baths in the country, to the city’s very best mosque, the hilltop Süleymaniye Camii. The best single reason to head across to the Asian shore of the city is to experience a Bosphorus cruise. The views from the Bosphorus are superb, with domes and minarets dominating the skyline of the Old City, and skyscrapers the business districts beyond Beyoğlu.

Kavala, Greece

Wind into lively alleys once known as the mecca of tobacco. Climb cobbled streets to Kavala’s old town and the Byzantine walled fortress. Wander the scenic walls to the whitewashed lighthouse for a chance to spot Mount Athos. Watch the amphitheatre put on a show at the top of Panagia, then descend into the Imaret complex of domes. Amble the taverna and bar-filled pedestrianised streets around Agios Nikolaos church and visit the atmospheric old hammam and mosaic memorial before routing to the ancient UNESCO city of Philippi. Refresh in waterfalls at the foot of Mount Pangaion, stroll to village watermills, neo-classical mansions, a celebrated winery and stockpile home-made honey. Float to leafy Thasos for coveted snow-white mined marble, archaeological sites and quaint old stone houses in Kastro. Then relax for Turkish coffee with a side of Greek schnapps in this quietly forgotten corner of Greece.

Thessaloniki

Breeze into a beguiling mix of vintage and modern, awash with a thriving art, culture and history scene. Crowded with museums dedicated to the past plus an extraordinary 15 UNESCO sites – there’s much to learn. Admire ramparts built to last; the impressive Galerius Palace, the beautiful domed multi-serving Rotunda, a bevy of Byzantine churches and the curious 15th century White Tower. Dig deeper into the past to trace pre-historic times at the Archaeological Museum. Rove around Ladadika narrow streets and charming squares that emit a Parisian air, absorb Greek produce in the Market’s holy halls and soak up modern art on the lively waterfront. Raise hairs at Heptapyrgion, take coffee in Aristotelous Square or head out of town to peer at Alexander the Great’s birthplace in Pella and Vergina’s royal tombs. Perfectly poised on the placid Thermaic Gulf, Thessaloniki brings past and present together in remarkable harmony.

Price tracking

Today’s fare, in context

Price history

30 days
Fare details

Fare details

Per person · taxes & fees included
Current fares
Verified 9 hours ago
Inside
$2,250
Oceanview
$2,625
Balcony
$3,825
Suite
$5,025
Tracked range
168 days
Price history by cabin type
CabinCurrentLowestHighest
Inside $2,250 $2,250 on Sep 1 $3,299 on Mar 25
Oceanview $2,625 $2,625 on Sep 1 $3,749 on Mar 25
Balcony $3,825 $3,825 on Sep 1 $5,399 on Mar 25
Suite $5,025 $5,025 on Sep 1 $7,499 on Mar 25
Cabin grades
16 total
Concierge VerandaBalcony · A1
Concierge VerandaBalcony · A2
Concierge VerandaBalcony · A3
Veranda StateroomBalcony · B1
Veranda StateroomBalcony · B2
Inside StateroomInside · F
Inside StateroomInside · G
Deluxe Ocean View StateroomOceanview · C1
Deluxe Ocean View StateroomOceanview · C2
Ocean View StateroomOceanview · D
Solo Oceanview StateroomOceanview · S
Owner's SuiteSuite · OS
Penthouse SuiteSuite · PH1
Penthouse SuiteSuite · PH2
Penthouse SuiteSuite · PH3
Vista SuiteSuite · VS

○ = last seen (sold out or delisted). · Verified 9 hours ago.

Lowest fares with no residency, age, or service requirement — verify eligibility at booking. How our pricing works

Current prices

Per person · 2 guests · incl. taxes & fees

Inside

from $2,250

$225 / night

Fare rows

Inside Stateroom

Cabin grade

Available

from $2,250

$225 / night

per person · incl. taxes & fees

Inside Stateroom

Cabin grade

Available

from $2,999

$299 / night

per person · incl. taxes & fees

Inside Stateroom

Cabin grade

Available

from $2,999

$299 / night

per person · incl. taxes & fees

Oceanview

from $2,625

$262 / night

Fare rows

Ocean View Stateroom

Cabin grade

Available

from $2,625

$262 / night

per person · incl. taxes & fees

Deluxe Ocean View Stateroom

Cabin grade

Available

from $2,850

$285 / night

per person · incl. taxes & fees

Deluxe Ocean View Stateroom

Cabin grade

Available

from $2,887

$288 / night

per person · incl. taxes & fees

Ocean View Stateroom

Cabin grade

Available

from $3,499

$349 / night

per person · incl. taxes & fees

Ocean View Stateroom

Cabin grade

Available

from $3,499

$349 / night

per person · incl. taxes & fees

Deluxe Ocean View Stateroom

Cabin grade

Available

from $3,799

$379 / night

per person · incl. taxes & fees

Deluxe Ocean View Stateroom

Cabin grade

Available

from $3,799

$379 / night

per person · incl. taxes & fees

Deluxe Ocean View Stateroom

Cabin grade

Available

from $3,849

$384 / night

per person · incl. taxes & fees

Deluxe Ocean View Stateroom

Cabin grade

Available

from $3,849

$384 / night

per person · incl. taxes & fees

Solo Oceanview Stateroom

Cabin grade

Available

from $6,399

$639 / night

per person · incl. taxes & fees

Solo Oceanview Stateroom

Cabin grade

Available

from $6,399

$639 / night

per person · incl. taxes & fees

Balcony

from $3,825

$382 / night

Fare rows

Veranda Stateroom

Cabin grade

Available

from $3,825

$382 / night

per person · incl. taxes & fees

Veranda Stateroom

Cabin grade

Available

from $3,900

$390 / night

per person · incl. taxes & fees

Concierge Veranda

Cabin grade

Available

from $3,975

$397 / night

per person · incl. taxes & fees

Concierge Veranda

Cabin grade

Available

from $4,050

$405 / night

per person · incl. taxes & fees

Concierge Veranda

Cabin grade

Available

from $4,200

$420 / night

per person · incl. taxes & fees

Veranda Stateroom

Cabin grade

Available

from $5,099

$509 / night

per person · incl. taxes & fees

Veranda Stateroom

Cabin grade

Available

from $5,099

$509 / night

per person · incl. taxes & fees

Veranda Stateroom

Cabin grade

Available

from $5,199

$519 / night

per person · incl. taxes & fees

Veranda Stateroom

Cabin grade

Available

from $5,199

$519 / night

per person · incl. taxes & fees

Concierge Veranda

Cabin grade

Available

from $5,299

$529 / night

per person · incl. taxes & fees

Concierge Veranda

Cabin grade

Available

from $5,299

$529 / night

per person · incl. taxes & fees

Concierge Veranda

Cabin grade

Available

from $5,399

$539 / night

per person · incl. taxes & fees

Concierge Veranda

Cabin grade

Available

from $5,399

$539 / night

per person · incl. taxes & fees

Concierge Veranda

Cabin grade

Available

from $5,599

$559 / night

per person · incl. taxes & fees

Concierge Veranda

Cabin grade

Available

from $5,599

$559 / night

per person · incl. taxes & fees

Suite

from $5,025

$502 / night

Fare rows

Penthouse Suite

Cabin grade

Available

from $5,025

$502 / night

per person · incl. taxes & fees

Penthouse Suite

Cabin grade

Available

from $5,100

$510 / night

per person · incl. taxes & fees

Penthouse Suite

Cabin grade

Available

from $5,175

$517 / night

per person · incl. taxes & fees

Penthouse Suite

Cabin grade

Available

from $6,699

$669 / night

per person · incl. taxes & fees

Penthouse Suite

Cabin grade

Available

from $6,699

$669 / night

per person · incl. taxes & fees

Penthouse Suite

Cabin grade

Available

from $6,799

$679 / night

per person · incl. taxes & fees

Penthouse Suite

Cabin grade

Available

from $6,799

$679 / night

per person · incl. taxes & fees

Penthouse Suite

Cabin grade

Available

from $6,899

$689 / night

per person · incl. taxes & fees

Penthouse Suite

Cabin grade

Available

from $6,899

$689 / night

per person · incl. taxes & fees

Vista Suite

Cabin grade

Available

from $12,149

$1,214 / night

per person · incl. taxes & fees

Vista Suite

Cabin grade

Available

from $12,149

$1,214 / night

per person · incl. taxes & fees

Owner's Suite

Cabin grade

Available

from $14,749

$1,474 / night

per person · incl. taxes & fees

Owner's Suite

Cabin grade

Available

from $14,749

$1,474 / night

per person · incl. taxes & fees

Prices verified Sep 7, 2026

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The journey

10 nights, in order

Istanbul

Day 1 Jul 9, 2027

Istanbul

A shore excursion on your MSC Mediterranean cruise can be the opportunity to discover İstanbul which stands astride two continents, Europe and Asia.

Explore Istanbul

Day by day

The full itinerary

11 scheduled calls
Sirena

Your ship

Sirena

Elegant sister ship to charming Regatta, Insignia and Nautica, Oceania Cruises’ newest addition, Sirena embodies the most treasured elements of our celebrated fleet, and features a few highlights all her own. With the introduction of two culinary experiences, Sirena offers even more ways to savor The Finest Cuisine at Sea. Tuscan Steak, a new specialty restaurant, serves Italian favorites, succulent steaks and fresh seafood inspired by Toscana and Polo Grill. The Grand Dining Room offers a surprise transformation into The Bistro during lunch, which serves classic French fare as well as regional specialties and lunchtime favorites. Also featuring the beloved restaurant Red Ginger, Sirena invites you to enjoy bold Asian cuisine in a fresh new way.

5★ 30,277 GT 670 Passengers Adults Only
Sirena ship guide Search cruises on Sirena

Deck plans

Deck plan for Deck 3

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from $2,250 pp

via CruiseDirect

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Book direct with Oceania Cruises we may earn a commission