The 21-Day Panama Canal & Southern Caribbean Holiday is a 21-night South America cruise aboard Nieuw Amsterdam, operated by Holland America Line. Departing Fort Lauderdale on December 27, 2026, the voyage visits 10 ports including Half Moon Cay, Oranjestad, Aruba, Cartagena, Colombia. Fares start from $4,204 per person.
Voyage code I687A
21 nights · South America
Why this route stands out
Price tracking
○ = last seen (sold out or delisted). · Verified 12 hours ago.
Lowest fares with no residency, age, or service requirement — verify eligibility at booking. How our pricing works
Per person · 2 guests · incl. taxes & fees
from $4,204
$200 / night
Standard Interior Stateroom
Cabin grade
from $4,204
$200 / night
per person · incl. taxes & fees
Standard Interior Stateroom
Cabin grade
from $4,304
$204 / night
per person · incl. taxes & fees
Standard Interior Stateroom
Cabin grade
from $4,364
$207 / night
per person · incl. taxes & fees
Standard Interior Stateroom
Cabin grade
from $4,424
$210 / night
per person · incl. taxes & fees
Large/Standard Inside Stateroom
Cabin grade
from $4,484
$213 / night
per person · incl. taxes & fees
from $4,294
$204 / night
Large Ocean view Stateroom (Fully Obstructed View)
Cabin grade
from $4,294
$204 / night
per person · incl. taxes & fees
Large Ocean view Stateroom
Cabin grade
from $4,384
$208 / night
per person · incl. taxes & fees
Large Ocean view Stateroom (Fully Obstructed View)
Cabin grade
from $4,424
$210 / night
per person · incl. taxes & fees
Large Ocean view Stateroom
Cabin grade
from $4,484
$213 / night
per person · incl. taxes & fees
Large Ocean view Stateroom (Partial Sea View)
Cabin grade
from $4,524
$215 / night
per person · incl. taxes & fees
Large Ocean view Stateroom
Cabin grade
from $4,584
$218 / night
per person · incl. taxes & fees
Large Ocean view Stateroom
Cabin grade
from $4,684
$223 / night
per person · incl. taxes & fees
Large Ocean view Stateroom
Cabin grade
from $4,784
$227 / night
per person · incl. taxes & fees
Not available
Not available
Prices verified Sep 9, 2026
This sailing
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The journey
Day by day
Your ship
The second of Holland America’s Signature Class ships, Nieuw Amsterdam, celebrates historic New York City with an inspired design and art collection. While on board, rejuvenate in the tranquil Spa & Salon, play pickleball at sea, or enjoy a tantalizing meal at fine dining restaurants. When you’re in the mood for music, Billboard Onboard fills the room with chart-topping hits.
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The Captain
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