Skip to main content
Miami, Florida

16 nights · Caribbean

16-night Caribbean cruise: Miami, Florida to Los Angeles, CA on Seven Seas Grandeur

The Panama Canal & Pacific Gems - Miami to Los Angeles is a 16-night Caribbean cruise aboard Seven Seas Grandeur, operated by Regent Seven Seas Cruises. Departing Miami, Florida on December 29, 2026 and arriving in Los Angeles, CA on January 14, 2027, the voyage visits 10 ports including George Town, Cayman Islands, Cartagena, Colombia, Panama Canal. Fares start from $14,349 per person.

Length
16 nights
Departs
Dec 29, 2026
Returns
Jan 14, 2027
Ports of call
10
Days at sea
7

Voyage code GRA261229

from $14,349 pp

via CruiseDirect

Book with CruiseDirect

Book direct with Regent Seven Seas Cruises we may earn a commission

Why this route stands out

A closer look at the journey

Fixed editorial images from the places on this itinerary. They stay stable each time you return to this sailing.

Miami, Florida

Miami is called the gateway to the Americas, and it’s indeed a very glamourous global city to explore at the start or end of an MSC Caribbean and Antilles cruise. Home to many cultures, the city of Miami sizzles with flavours from the Americas, beginning with Cuba and the Little Havana neighbourhood - one of the most historically significant places, while Wynwood is famous for its wall art and Puerto Rican history. Across Biscayne Bay lies the city of Miami Beach, home to the world-famous South Beach. An MSC-arranged guided private tour opens up a world of possibilities for you: enjoy the beach, take in the city’s Art Deco architecture and enjoy a drink on legendary Ocean Drive, where you can people watch, and perhaps spot a celebrity. If time permits, take a stroll on artsy Lincoln Road packed with street side cafes and shops. Facing the MSC Cruises port in downtown Miami is Bayside Marketplace - a lively commercial centre that is a staging area for boat tours of Miami. Seeing the city from the water, with its impressive skyline and waterfront mansions, is an experience in itself. The downtown area also boasts the dazzling Performing Arts Centre, the Museum of Science, the Pérez Art Museum Miami (known as the PAMM), scenic Bayfront Park and the arena where the 3-time NBA champion Miami Heat basketball team plays. Miami is renowned for its shopping. Hop on a tour to see the major city sights followed by retail therapy at one of Miami's largest and newest shopping malls: Dolphin Mall. With more than 240 retail outlets, you’re bound to need a bit of room in your luggage for your purchases. Luckily, there are several luggage stores at the mall to fill that need. Head west past the city into untamed wilderness on an MSC excursion into the Everglades. At this national park where water is the central feature, unlike any other in North America, nature enthusiasts can hop on an airboat tour through the swampland and waterways to spot alligators and a variety of birds.

George Town, Cayman Islands

Christopher Columbus called the Cayman Islands, with their tranquil blue waters, "Las Tortugas" for its abundance of turtles. Located between Cuba and Jamaica, the Cayman Islands are comprised of three Caribbean islands: Grand Cayman, Little Cayman and Cayman Brac. Beautiful landscapes, bountiful wildlife and colourful streets embody this British Overseas Territory, with George Town, its capital, located on Grand Cayman, the largest and most populous island. When you arrive in George Town on an MSC Caribbean and Antilles cruise, you’ll discover that wildlife conservation is at the core of Grand Cayman’s offerings. For the chance of a lifetime to swim, feed and interact with stingrays, book an MSC excursion to Stingray City, where you’ll get an up-close experience with Cayman’s most graceful marine creatures. On yet another MSC excursion to the Cayman Turtle Centre, encounter the green turtles that return each and every year to lay their eggs on one of the beaches, visit the turtle hatchery, snorkel alongside yearlings in the Turtle Lagoon and meet the island’s endangered blue iguanas. For a special experience, ride horses bareback into the Caribbean Sea at Barker’s National Park on an exclusive Martha Stewart excursion curated just for MSC Cruises, followed by lunch at Vivo café, a spot beloved for its mostly vegan cuisine, with organic ingredients sourced straight from local farms. To learn about Cayman’s past and culture, explore Cayman Heritage House and visit the sumptuous Government House, the governor's residence built in 1964 located in front of Seven Mile Beach, one of the most prestigious beaches of Grand Cayman, in the heart of West Bay. Shopaholics will also delight in this destination. The Cayman Islands are entirely duty free. You just have to choose what catches your fancy among the myriad of watches, liqueurs, jewellery and porcelain on offer.

Cartagena, Colombia

Cobbled streets, balconies overflowing with blooming bougainvillea and pastel-coloured buildings lining elegant plazas make Cartagena in Colombia one of the Caribbean's most photogenic cities, and a memorable stop on an MSC Caribbean and Antilles cruise. Founded in 1533, this Spanish colonial city, a UNESCO World Heritage Site, is steeped in history. Its location made it a popular target for plunderers and English pirates, and arguably features the most impressive collection of forts in the Caribbean. Today the city is eager to share its treasures with modern visitors. Magnificent colonial structures such as the 16th-century Santa Catalina Cathedral, with its striking stuccoes and dome tower, and the three-arch clock gate, the Torre del Reloj, are just two of the many landmarks of this enchanting city dotted with many squares and sidewalk cafés. A wonderful photo stop on our Cartagena City MSC excursion is the San Felipe de Barajas fortress, a marvel of colonial Spanish military engineering. Its construction began in 1536. Slaves la-boured for more than 120 years to erect this fortress - built on high ground with dominating ap-proaches to the city by land and sea to fend off pirates - and its network of tunnels. On yet another MSC excursion, enrich your palate as you learn about the rich aromas and flavours of Colombian coffee. Introduced by the Jesuits in 1723, coffee quickly became a key crop in Colombia, which is now one of the top producers of Arabica coffee in the world. Colombia is also the world’s top producer of emeralds. If jewellery and gems fascinate you, learn all about these green precious stones and make your own emerald-studded jewellery in sterling silver during a hands-on MSC excursion that guides you step-by-step. And you don’t need to go far to explore nature. An MSC excursion takes you by canoe through mangrove tunnels to Ciénaga de la Virgen, where you can witness a diversity of birds from king-fishers and white herons to pelicans and pink-feathered roseate spoonbills.

Price tracking

Today’s fare, in context

Price history

Cheaper than 45%
30 days
Fare details

Fare details

Per person · taxes & fees included
Current fares
Verified 1 day ago
Suite
$14,349
Tracked range
160 days
Price history by cabin type
CabinCurrentLowestHighest
Suite $14,349 $13,299 on Mar 25 $14,699 on Jun 13
Cabin grades
15 total
Penthouse SuiteSuite · A
Penthouse SuiteSuite · B
Penthouse SuiteSuite · C
Concierge SuiteSuite · D
Concierge SuiteSuite · E
Serenity SuiteSuite · F1
Serenity SuiteSuite · F2
Deluxe Veranda SuiteSuite · G1
Deluxe Veranda SuiteSuite · G2
Grandeur SuiteSuite · GN
Grand SuiteSuite · GS
Veranda SuiteSuite · H
Regent SuiteSuite · RS
Signature SuiteSuite · SG
Seven Seas SuiteSuite · SS

○ = last seen (sold out or delisted). · Verified 1 day ago.

Lowest fares with no residency, age, or service requirement — verify eligibility at booking. How our pricing works

Want to know when this fare changes?

Get price alerts

Current prices

Per person · 2 guests · incl. taxes & fees

Inside

Not available

Oceanview

Not available

Balcony

Not available

Suite

from $14,349

$896 / night

Fare rows

Veranda Suite

Cabin grade

Available

from $14,349

$896 / night

per person · incl. taxes & fees

Deluxe Veranda Suite

Cabin grade

Available

from $14,699

$918 / night

per person · incl. taxes & fees

Deluxe Veranda Suite

Cabin grade

Available

from $14,749

$921 / night

per person · incl. taxes & fees

Serenity Suite

Cabin grade

Available

from $15,349

$959 / night

per person · incl. taxes & fees

Serenity Suite

Cabin grade

Available

from $16,099

$1,006 / night

per person · incl. taxes & fees

Concierge Suite

Cabin grade

Available

from $16,259

$1,016 / night

per person · incl. taxes & fees

Veranda Suite

Cabin grade

Available

from $16,949

$1,059 / night

per person · incl. taxes & fees

Deluxe Veranda Suite

Cabin grade

Available

from $17,299

$1,081 / night

per person · incl. taxes & fees

Deluxe Veranda Suite

Cabin grade

Available

from $17,349

$1,084 / night

per person · incl. taxes & fees

Serenity Suite

Cabin grade

Available

from $17,949

$1,121 / night

per person · incl. taxes & fees

Serenity Suite

Cabin grade

Available

from $18,699

$1,168 / night

per person · incl. taxes & fees

Concierge Suite

Cabin grade

Available

from $19,049

$1,190 / night

per person · incl. taxes & fees

Prices verified Aug 29, 2026

Prices come from third-party data feeds via Regent Seven Seas Cruises and may differ from the cruise line's current fare. Confirm the final price before booking. How our pricing works

Lowest fares with no residency, age, or service requirement — verify eligibility at booking. How our pricing works

Not ready to book?

Get price alerts

We’ll email you when fares drop or return.

Free. Confirm by email. Unsubscribe anytime.

Advanced options Cabins & price targets

Choose a cabin, then select any price drop, a percentage, or a target price.

at or below $

The journey

16 nights, in order

Follow the entire sailing from its first day to its last, with the route and schedule in one view.

Miami, Florida

Day 1 Dec 29, 2026

Miami, Florida

Miami is called the gateway to the Americas, and it’s indeed a very glamourous global city to explore at the start or end of an MSC Caribbean and Antilles cruise.

Explore Miami, Florida

Day by day

The full itinerary

17 scheduled calls
Seven Seas Grandeur

Your ship

Seven Seas Grandeur

For more than thirty years, we have delivered unrivaled experiences throughout the world. All the while, we have been listening to our guests, evolving our services and continually refining each element of the Regent experience. Embrace the freedom enjoyed through the most all-inclusive luxury experience on the Seven Seas aboard a ship that elevates the pinnacle of ocean cruising to new heights. Inspired by the past and stunningly reimagined for the future, Seven Seas Grandeur™ will exemplify our heritage of perfection with unrivaled space, unparalleled service, exceptional cuisine and transformative experiences that will begin the moment you step aboard.

6★ 55,498 GT 746 Passengers Built 2021
Seven Seas Grandeur ship guide Search cruises on Seven Seas Grandeur

Deck plans

Deck plan for Deck 4

Scroll to explore · Double-tap to zoom

Keep exploring

More ways to take this journey

Fly-cruise options

Fly-cruise package options
Airport Price pp Included
ABQ $16,999.00 Extra
ALB $17,069.00 Extra
ATL $16,929.00 Extra
AUS $17,099.00 Extra
AVL $16,949.00 Extra
BDL $17,069.00 Extra
BFL $16,979.00 Extra
BHM $17,079.00 Extra
BIL $16,939.00 Extra
BNA $17,079.00 Extra
BOI $16,999.00 Extra
BOS $16,869.00 Extra
BUF $17,069.00 Extra
BWI $16,959.00 Extra
CHA $16,939.00 Extra
CHS $17,079.00 Extra
CID $17,099.00 Extra
CLE $17,079.00 Extra
CLT $17,049.00 Extra
CMH $17,079.00 Extra
COS $16,939.00 Extra
CVG $17,079.00 Extra
DCA $16,929.00 Extra
DEN $16,879.00 Extra
DFW $16,879.00 Extra
DSM $17,099.00 Extra
DTW $17,009.00 Extra
ELP $16,999.00 Extra
EUG $16,979.00 Extra
EWR $16,869.00 Extra
FAR $17,099.00 Extra
FAT $16,999.00 Extra
FSD $16,939.00 Extra
GEG $16,979.00 Extra
GRR $17,079.00 Extra
GSO $16,999.00 Extra
GSP $17,079.00 Extra
GTF $16,999.00 Extra
HNL $16,999.00 Extra
HSV $17,079.00 Extra
IAD $16,929.00 Extra
IAH $16,879.00 Extra
ICT $17,099.00 Extra
ILM $16,949.00 Extra
IND $17,079.00 Extra
JAN $17,099.00 Extra
JAX $17,059.00 Extra
JFK $16,869.00 Extra
LAS $16,999.00 Extra
LAX $16,479.00 Extra
LBB $17,099.00 Extra
LEX $16,939.00 Extra
LGA $16,869.00 Extra
LIT $17,099.00 Extra
MAF $16,939.00 Extra
MCI $17,099.00 Extra
MCO $16,869.00 Extra
MDW $16,909.00 Extra
MEM $17,079.00 Extra
MIA $16,409.00 Extra
MKE $17,099.00 Extra
MOB $17,079.00 Extra
MSN $17,099.00 Extra
MSP $16,949.00 Extra
MSY $17,099.00 Extra
MYR $16,949.00 Extra
OKC $17,099.00 Extra
OMA $17,099.00 Extra
ORD $16,909.00 Extra
ORF $17,079.00 Extra
PDX $16,999.00 Extra
PHL $17,049.00 Extra
PHX $16,899.00 Extra
PIA $16,939.00 Extra
PIT $17,079.00 Extra
PSP $16,999.00 Extra
PVD $17,069.00 Extra
PWM $17,069.00 Extra
RDU $17,079.00 Extra
RIC $17,079.00 Extra
RNO $16,999.00 Extra
ROC $17,069.00 Extra
SAN $16,899.00 Extra
SAT $17,079.00 Extra
SAV $16,959.00 Extra
SBA $16,999.00 Extra
SDF $17,079.00 Extra
SEA $16,929.00 Extra
SFO $16,989.00 Extra
SGF $16,939.00 Extra
SHV $17,099.00 Extra
SLC $16,999.00 Extra
SMF $16,999.00 Extra
SNA $16,559.00 Extra
STL $17,099.00 Extra
SYR $17,069.00 Extra
TPA $16,909.00 Extra
TUL $17,099.00 Extra
TUS $16,999.00 Extra
TYS $17,079.00 Extra
XNA $16,939.00 Extra
YEG $16,999.00 Extra
YOW $17,069.00 Extra
YUL $16,949.00 Extra
YVR $16,969.00 Extra
YYC $16,999.00 Extra
YYJ $16,979.00 Extra
YYZ $16,889.00 Extra

Ready when you are

Book now or get price alerts

Book this cruise

from $14,349 pp

Book with CruiseDirect

via CruiseDirect Cruise line site Affiliate disclosure

Get price alerts

We’ll email you when fares drop or return.

Free. Confirm by email. Unsubscribe anytime.

Advanced options Cabins & price targets

Choose a cabin, then select any price drop, a percentage, or a target price.

at or below $

from $14,349 pp

via CruiseDirect

Book with CruiseDirect

Book direct with Regent Seven Seas Cruises we may earn a commission