Puerto Vallarta, Mexico
One of the places included in this itinerary.
The 15 Night Panama Canal Eastward Cruise is a 15-night Caribbean cruise aboard Serenade of the Seas, operated by Royal Caribbean. Departing San Diego, California on October 7, 2027 and arriving in Tampa on October 22, 2027, the voyage visits 8 ports including Puerto Vallarta, Mexico, Puerto Quetzal, Puntarenas, Costa Rica. Fares start from $2,156 per person.
Voyage code SR15T253
15 nights · Caribbean
Why this route stands out
Price tracking
○ = last seen (sold out or delisted). · Verified 9 minutes ago.
Lowest fares with no residency, age, or service requirement — verify eligibility at booking. How our pricing works
Per person · 2 guests · incl. taxes & fees
from $2,156
$143 / night
Interior Stateroom - Guaranteed
Cabin grade
from $2,156
$143 / night
per person · incl. taxes & fees
Interior
Cabin grade
from $2,345
$156 / night
per person · incl. taxes & fees
Interior
Cabin grade
from $2,385
$159 / night
per person · incl. taxes & fees
from $2,385
$159 / night
Ocean View - Guaranteed
Cabin grade
from $2,385
$159 / night
per person · incl. taxes & fees
Ocean View
Cabin grade
from $2,506
$167 / night
per person · incl. taxes & fees
Ocean View
Cabin grade
from $2,525
$168 / night
per person · incl. taxes & fees
Ocean View
Cabin grade
from $2,555
$170 / night
per person · incl. taxes & fees
Oceanview
Cabin grade
from $2,555
$170 / night
per person · incl. taxes & fees
Not available
Not available
Prices verified Sep 10, 2026
This sailing
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The journey
Day by day
Your ship
Dive into new discoveries as you sail onboard Serenade of the Seas. Wherever in the world you’re sailing, Serenade of the Seas keeps you close to all the natural splendour. Once onboard, panoramic views and acres of glass ensure that you’ll never miss a moment of the surrounding scenery. In between adventures onshore, you can soak up the sun poolside, tee off on the mini golf green and dig into world-class flavours that will take you from Tuscany to Tokyo.
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