21-night Western Mediterranean cruise: Santos, Brazil to Naples on MSC Virtuosa

The 21 nights South America from Santos (Sao Paulo) is a 21-night Western Mediterranean cruise aboard MSC Virtuosa, operated by MSC Cruises. Departing Sao Paulo on April 3, 2027 and arriving in Naples on April 24, 2027, the voyage visits 11 ports including Rio de Janeiro, Buzios, Salvador. CruiseCaptain has fare history for this sailing.

Length: 21 nights
Departs: Apr 3, 2027
Returns: Apr 24, 2027
Ports of call: 11
Days at sea: 11

Voyage code VI20270403SSZNAP

21 nights · Western Mediterranean

Call for price

per person

Book

via CruiseDirect Direct on MSC Cruises Affiliate link

Call for price

via CruiseDirect

Book

Book direct with MSC Cruises we may earn a commission

Why this route stands out

A closer look at the journey

Santos, Brazil

One of the places included in this itinerary.

Rio de Janeiro

One of the places included in this itinerary.

Buzios

One of the places included in this itinerary.

Price tracking

Today’s fare, in context

Price history

Cheaper than 76%

30 days

Fare details

Price history by cabin type
Cabin	Last recorded	Lowest	Highest
Inside	$1,861 · Aug 22	$1,265 on Aug 6	$1,861 on Jul 8
Oceanview	$2,211 · Aug 9	$1,615 on Jul 25	$2,709 on Jul 3
Balcony	$2,655 · Oct 8	$2,321 on Mar 25	$5,652 on Aug 27
Suite	$10,551 · Sep 4	$10,551 on Sep 4	$19,900 on Sep 3

○ = last seen (sold out or delisted).

Lowest fares with no residency, age, or service requirement — verify eligibility at booking. How our pricing works

Get fare alerts

Cabin grades

Lines step when the price changed; a gap means sold out or no public fare that day. Plot up to 6 at once.

Current prices

Per person · 2 guests

Tax and fee inclusion varies by fare source. Confirm the total, including any additional charges, before booking.

Price information is not available.

This sailing

Catch the next fare drop

We’ll email you when this sailing’s fare drops or returns.

The journey

21 nights, in order

Day 1 Apr 3, 2027

Santos, Brazil
Explore Santos, Brazil

Day by day

The full itinerary

22 scheduled calls

Your ship

MSC Virtuosa

MSC Virtuosa’s namesake comes from the word virtuoso, meaning someone highly skilled in any field of activity, and so MSC Virtuosa was named to pay homage to the skill and expertise of the MSC Cruises architects and shipyard partners at Les Chantiers de l’Atlantique who designed and built this innovative class of ships. This new cruise ship is one of the two largest in MSC Cruises’ fleet, along with her sister ship MSC Grandiosa, boasting an impressive array of guest features all coming together in perfect harmony to deliver the ultimate cruise holiday experience.

5★ 181,541 GT 6,334 Passengers Built 2019

MSC Virtuosa